2,466 research outputs found

    Particle Dispersion on Rapidly Folding Random Hetero-Polymers

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    We investigate the dynamics of a particle moving randomly along a disordered hetero-polymer subjected to rapid conformational changes which induce superdiffusive motion in chemical coordinates. We study the antagonistic interplay between the enhanced diffusion and the quenched disorder. The dispersion speed exhibits universal behavior independent of the folding statistics. On the other hand it is strongly affected by the structure of the disordered potential. The results may serve as a reference point for a number of translocation phenomena observed in biological cells, such as protein dynamics on DNA strands.Comment: 4 pages, 4 figure

    Shannon entropy of brain functional complex networks under the influence of the psychedelic Ayahuasca

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    The entropic brain hypothesis holds that the key facts concerning psychedelics are partially explained in terms of increased entropy of the brain's functional connectivity. Ayahuasca is a psychedelic beverage of Amazonian indigenous origin with legal status in Brazil in religious and scientific settings. In this context, we use tools and concepts from the theory of complex networks to analyze resting state fMRI data of the brains of human subjects under two distinct conditions: (i) under ordinary waking state and (ii) in an altered state of consciousness induced by ingestion of Ayahuasca. We report an increase in the Shannon entropy of the degree distribution of the networks subsequent to Ayahuasca ingestion. We also find increased local and decreased global network integration. Our results are broadly consistent with the entropic brain hypothesis. Finally, we discuss our findings in the context of descriptions of "mind-expansion" frequently seen in self-reports of users of psychedelic drugs.Comment: 27 pages, 6 figure

    Characterization of the Noise in Secondary Ion Mass Spectrometry Depth Profiles

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    The noise in the depth profiles of secondary ion mass spectrometry (SIMS) is studied using different samples under various experimental conditions. Despite the noise contributions from various parts of the dynamic SIMS process, its overall character agrees very well with the Poissonian rather than the Gaussian distribution in all circumstances. The Poissonian relation between the measured mean-square error (MSE) and mean can be used to describe our data in the range of four orders. The departure from this relation at high counts is analyzed and found to be due to the saturation of the channeltron used. Once saturated, the detector was found to exhibit hysteresis between rising and falling input flux and output counts.Comment: 14 pages, 4 postscript figures, to appear on J. Appl. Phy

    School screening program: update of the prevalence of overweight and obesity between 1996 and 2017

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    Within the School Screening Program, around 16 school nurses measure selected health indicators every year, including weight, height and selected other lifestyles variables in all ~5800 students in the C2, P4, S1 and S4 grades in all schools. • Overweight and obesity are defined along standard age and sex specific criteria by the International Obesity Task Force (IOTF). • In 2017, weight and height were measured in 3351 students from 5760 eligible students, a participation rate of only 58%. The disappointingly low participation rate in 2017, and in recent years in general, seems to be partially related to the fact that school nurses often cannot run the school program because of concurrent duties in health centers. This issue should be addressed urgently if the screening program is to be sustained in 2018. • The prevalence of overweight or obesity in children aged 9-16 years (P4, S1 and S4) increased by more than two times, between 1998 and 2017, from 9.3% to 26.4% in boys and from 12.9% in 1998 to 28.5% in girls. The current levels are extremely high by international comparison. The steep linear increase over time, including in recent years, underlies a major public health problem

    Long-Range Navigation on Complex Networks using L\'evy Random Walks

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    We introduce a strategy of navigation in undirected networks, including regular, random, and complex networks, that is inspired by L\'evy random walks, generalizing previous navigation rules. We obtained exact expressions for the stationary probability distribution, the occupation probability, the mean first passage time, and the average time to reach a node on the network. We found that the long-range navigation using the L\'evy random walk strategy, compared with the normal random walk strategy, is more efficient at reducing the time to cover the network. The dynamical effect of using the L\'evy walk strategy is to transform a large-world network into a small world. Our exact results provide a general framework that connects two important fields: L\'evy navigation strategies and dynamics on complex networks.Comment: 6 pages, 3 figure

    First passages in bounded domains: When is the mean first passage time meaningful?

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    We study the first passage statistics to adsorbing boundaries of a Brownian motion in bounded two-dimensional domains of different shapes and configurations of the adsorbing and reflecting boundaries. From extensive numerical analysis we obtain the probability P(\omega) distribution of the random variable \omega=\tau_1/(\tau_1+\tau_2), which is a measure for how similar the first passage times \tau_1 and \tau_2 are of two independent realisations of a Brownian walk starting at the same location. We construct a chart for each domain, determining whether P(\omega) represents a unimodal, bell-shaped form, or a bimodal, M-shaped behaviour. While in the former case the mean first passage time (MFPT) is a valid characteristic of the first passage behaviour, in the latter case it is an insufficient measure for the process. Strikingly we find a distinct turnover between the two modes of P(\omega), characteristic for the domain shape and the respective location of absorbing and reflective boundaries. Our results demonstrate that large fluctuations of the first passage times may occur frequently in two-dimensional domains, rendering quite vague the general use of the MFPT as a robust measure of the actual behaviour even in bounded domains, in which all moments of the first passage distribution exist.Comment: 9 pages, 6 figure

    Spontaneous symmetry breaking in amnestically induced persistence

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    We investigate a recently proposed non-Markovian random walk model characterized by loss of memories of the recent past and amnestically induced persistence. We report numerical and analytical results showing the complete phase diagram, consisting of 4 phases, for this system: (i) classical nonpersistence, (ii) classical persistence (iii) log-periodic nonpersistence and (iv) log-periodic persistence driven by negative feedback. The first two phases possess continuous scale invariance symmetry, however log-periodicity breaks this symmetry. Instead, log-periodic motion satisfies discrete scale invariance symmetry, with complex rather than real fractal dimensions. We find for log-periodic persistence evidence not only of statistical but also of geometric self-similarity.Comment: 4 pages, 2 color fig

    Amnestically induced persistence in random walks

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    We study how the Hurst exponent α\alpha depends on the fraction ff of the total time tt remembered by non-Markovian random walkers that recall only the distant past. We find that otherwise nonpersistent random walkers switch to persistent behavior when inflicted with significant memory loss. Such memory losses induce the probability density function of the walker's position to undergo a transition from Gaussian to non-Gaussian. We interpret these findings of persistence in terms of a breakdown of self-regulation mechanisms and discuss their possible relevance to some of the burdensome behavioral and psychological symptoms of Alzheimer's disease and other dementias.Comment: 4 pages, 3 figs, subm. to Phys. Rev. Let

    Analyzing the House Fly's Exploratory Behavior with Autoregression Methods

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    This paper presents a detailed characterization of the trajectory of a single housefly with free range of a square cage. The trajectory of the fly was recorded and transformed into a time series, which was fully analyzed using an autoregressive model, which describes a stationary time series by a linear regression of prior state values with the white noise. The main discovery was that the fly switched styles of motion from a low dimensional regular pattern to a higher dimensional disordered pattern. This discovered exploratory behavior is, irrespective of the presence of food, characterized by anomalous diffusion.Comment: 20 pages, 9 figures, 1 table, full pape

    QCD Strings as Constrained Grassmannian Sigma Model:

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    We present calculations for the effective action of string world sheet in R3 and R4 utilizing its correspondence with the constrained Grassmannian sigma model. Minimal surfaces describe the dynamics of open strings while harmonic surfaces describe that of closed strings. The one-loop effective action for these are calculated with instanton and anti-instanton background, reprsenting N-string interactions at the tree level. The effective action is found to be the partition function of a classical modified Coulomb gas in the confining phase, with a dynamically generated mass gap.Comment: 22 pages, Preprint: SFU HEP-116-9
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