Space shuttle plume/simulation application

An analysis of pressure and strain-gage data from space shuttle wind tunnel test IA119 and IA138 was performed to define the influence on aerodynamic characteristics resulting from the main propulsion system and solid rocket booster plumes. Aerodynamic characteristics of each of the elements, the components and total vehicle of the space shuttle vehicle during ascent flight was considered. Pressure data were obtained over the aft portions of the space shuttle wind tunnel model in addition to wing and elevon gage data

The IRAS 1-Jy Survey of Ultraluminous Infrared Galaxies: I. The sample and Luminosity Function

A complete flux-limited sample of 118 ultraluminous infrared galaxies (ULIGs) has been identified from the IRAS Faint Source Catalog (FSC). The selection criteria were a 60 micron flux density greater than 1 Jy in a region of the sky delta > -40 deg, |b| > 30 deg. All sources were subsequently reprocessed using coadded IRAS maps in order to obtain the best available flux estimates in all four IRAS wavelength bands. The maximum observed infrared luminosity is L_ir = 10^{12.90} L_{sun}, and the maximum redshift is z = 0.268. The luminosity function for ULIGs over the decade luminosity range L_ir = 10^{12} - 10^{13} L_{sun} can be approximated by a power law Phi (L) ~= L^{-2.35} Mpc^{-3} mag^{-1}. In the local Universe z < 0.1, the space density of ULIGs appears to be comparable to or slightly larger than that of optically selected QSOs at comparable bolometric luminosities. A maximum likelihood test suggests strong evolution for our sample; assuming density evolution proportional to (1+z)^{alpha} we find alpha = 7.6+/-3.2. Examination of the two-point correlation function shows a barely significant level of clustering, xi (r) = 1.6 +/- 1.2, on size scales r ~= 22 h^{-1} Mpc.Comment: 18 pages of text, 10 pages of figures 1 to 6, 6 pages of tables 1 to 3, ApJS accepte

Gravitational Lensing of the X-Ray Background by Clusters of Galaxies

Gravitational lensing by clusters of galaxies affects the cosmic X-ray background (XRB) by altering the observed density and flux distribution of background X-ray sources. At faint detection flux thresholds, the resolved X-ray sources appear brighter and diluted, while the unresolved component of the XRB appears dimmer and more anisotropic, due to lensing. The diffuse X-ray intensity in the outer halos of clusters might be lower than the sky-averaged XRB, after the subtraction of resolved sources. Detection of the lensing signal with a wide-field X-ray telescope could probe the mass distribution of a cluster out to its virialization boundary. In particular, we show that the lensing signature imprinted on the resolved component of the XRB by the cluster A1689, should be difficult but possible to detect out to 8' at the 2-4 sigma level, after 10^6 seconds of observation with the forthcoming AXAF satellite. The lensing signal is fairly insensitive to the lens redshift in the range 0.1<z<0.6. The amplitude of the lensing signal is however sensitive to the faint end slope of the number-flux relation for unresolved X-ray sources, and can thus help constrain models of the XRB. A search for X-ray arcs or arclets could identify the fraction of all faint sources which originate from extended emission of distant galaxies. The probability for a 3 sigma detection of an arclet which is stretched by a factor of about 3 after a 10^6 seconds observation of A1689 with AXAF, is roughly comparable to the fraction of all background X-ray sources that have an intrinsic size of order 1''.Comment: 41 LaTeX pages, 11 postscript figures, 1 table, in AASTeX v4.0 format. To appear in ApJ, April 1, 1997, Vol. 47

Conjugatable water-soluble Pt(ii) and Pd(ii) porphyrin complexes: Novel nano- and molecular probes for optical oxygen tension measurement in tissue engineering

Measurement of oxygen tension in compressed collagen sheets was performed using matrix-embedded optical oxygen sensors based on platinum(II) and palladium(II) porphyrins supported on polyacrylamide nanoparticles. Bespoke, fully water-soluble, mono-functionalised Pt(II) and Pd(II) porphyrin complexes designed for conjugation under mild conditions were obtained using microwave-assisted metallation. The new sensors display a linear response (1/τ vs. O₂) to varying oxygen tension over a biologically relevant range (7.0 × 10⁻⁴ to 2.7 × 10⁻¹ mM) in aqueous solutions; a behaviour that is maintained following conjugation to polyacrylamide nanoparticles, and following embedding of the nanosensors in compressed collagen sheets, paving the way to innovative approaches for real-time resolution of oxygen gradients throughout 3D matrices useful for tissue regeneration

Intra-session and inter-day reliability of the Myon 320 electromyography system during sub-maximal contractions

Electromyography systems are widely used within the field of scientific and clinical practices. The reliability of these systems are paramount when conducting research. The reliability of Myon 320 Surface Electromyography System is yet to be determined. This study aims to determine the intra-session and inter-day reliability of the Myon 320 Surface Electromyography System. Muscle activity from fifteen participants was measured at the anterior deltoid muscle during a bilateral front raise exercise, the vastus lateralis muscle during a squat exercise and the extensor carpi radialis brevis (ECRB) muscle during an isometric handgrip task. Intra-session and inter-day reliability was calculated by intraclass correlation coefficient, standard error of measurement and coefficient of variation (CV). The normalized root mean squared (RMS) surface electromyographic signals produced good intra-session and inter-day testing intraclass correlation coefficient values (range: 0.63-0.97) together with low standard error of measurement (range: 1.49-2.32) and CV (range: 95% Confidence Interval = 0.36-12.71) measures for the dynamic-and-isometric contractions. The findings indicate that the Myon 320 Surface Electromyography System produces good to fair reliability when examining intra-session and inter-day reliability. Findings of the study provide evidence of the reliability of electromyography between trials which is essential during clinical testing.</p

Compact Nuclei in Galaxies at Moderate Redshift:II. Their Nature and Implications for the AGN Luminosity Function

This study explores the space density and properties of active galaxies to z=0.8. We have investigated the frequency and nature of unresolved nuclei in galaxies at moderate redshift as indicators of nuclear activity such as Active Galactic Nuclei (AGN) or starbursts. Candidates are selected by fitting imaged galaxies with multi-component models using maximum likelihood estimate techniques to determine the best model fit. We select those galaxies requiring an unresolved point-source component in the galaxy nucleus, in addition to a disk and/or bulge component, to adequately model the galaxy light. We have searched 70 WFPC2 images primarily from the Medium Deep Survey for galaxies containing compact nuclei. In our survey of 1033 galaxies, the fraction containing an unresolved nuclear component greater than 5% of the total galaxy light is 9+/-1% corrected for incompleteness. In this second of two papers in this series, we discuss the nature of the compact nuclei and their hosts. We present the upper limit luminosity function (LF) for low-luminosity AGN (LLAGN) in two redshift bins to z=0.8. Mild number density evolution is detected for nuclei at -18 -16 and this flatness, combined with the increase in number density, is inconsistent with pure luminosity evolution. Based on the amount of density evolution observed for these objects, we find that almost all present-day spiral galaxies could have hosted a LLAGN at some point in their lives. We also comment on the likely contribution of these compact nuclei to the soft X-ray background.Comment: 50 pages, 14 figures, to appear in ApJ, April 199

The anti-emetic potential of the 5-hydroxytryptamine3 receptor antagonist BRL 43694.

In ferrets, the selective 5-hydroxytryptamine (5-HT) 5-HT3 receptor antagonist BRL 43694 given as a single injection (0.05-0.5 mg kg-1 i.v.) before cisplatin, or by divided dose (2 x 0.005-2 x 0.5 mg kg-1 i.v.) before and after cisplatin dramatically reduced or abolished the severe cisplatin-induced vomiting. BRL 43694 also substantially reduced the vomiting induced by cyclophosphamide:doxorubicin, and prevented the trimelamol-induced emesis. The severe emesis caused by whole body exposure to X-irradiation was prevented by intravenous or oral BRL 43694. A single i.v. dose of BRL 43694 given during an emetic episode or within the peak emetic period, abolished the vomiting induced by the cytotoxic drugs and by X-irradiation, usually within 30 s. Where the induction of emesis was prevented or subsequently abolished by BRL 43694, the associated behaviour (subjectively assessed as nausea) was also absent or greatly attenuated. BRL 43694 (0.1 mg kg-1 i.v.) did not affect the emesis evoked in dogs by the dopamine agonist apomorphine. The potent anti-emetic activity of BRL 43694 is discussed in terms of potential clinical use, and of the fundamental role that 5-HT3 receptors may play in the mechanisms of nausea and vomiting

The Luminosity Function of X-ray Selected Active Galactic Nuclei: Evolution of Supermassive Black Holes at High Redshift

We present a measure of the hard (2-8 keV) X-ray luminosity function (XLF) of Active Galactic Nuclei up to z~5. At high redshifts, the wide area coverage of the Chandra Multiwavength Project is crucial to detect rare and luminous (Lx > 10^44 erg s^-1) AGN. The inclusion of samples from deeper published surveys, such as the Chandra Deep Fields, allows us to span the lower Lx range of the XLF. Our sample is selected from both the hard (z 6.3x10^-16 erg cm^-2 s^-1) and soft (z > 3; f(0.5-2.0 keV) > 1.0x10^-16 erg cm^-2 s^-1) energy band detections. Within our optical magnitude limits (r',i' < 24), we achieve an adequate level of completeness (>50%) regarding X-ray source identification (i.e., redshift). We find that the luminosity function is similar to that found in previous X-ray surveys up to z~3 with an evolution dependent upon both luminosity and redshift. At z > 3, there is a significant decline in the numbers of AGN with an evolution rate similar to that found by studies of optically-selected QSOs. Based on our XLF, we assess the resolved fraction of the Cosmic X-ray Background, the cumulative mass density of Supermassive Black Holes (SMBHs), and the comparison of the mean accretion rate onto SMBHs and the star formation history of galaxies as a function of redshift. A coevolution scenario up to z~2 is plausible though at higher redshifts the accretion rate onto SMBHs drops more rapidly. Finally, we highlight the need for better statistics of high redshift AGN at z > 3, which is achievable with the upcoming Chandra surveys.Comment: Accepted for publication in ApJ; 25 pages, 18 figure

Periodic Bursts of Coherent Radio Emission from an Ultracool Dwarf

We report the detection of periodic (p = 1.96 hours) bursts of extremely bright, 100% circularly polarized, coherent radio emission from the M9 dwarf TVLM 513-46546. Simultaneous photometric monitoring observations have established this periodicity to be the rotation period of the dwarf. These bursts, which were not present in previous observations of this target, confirm that ultracool dwarfs can generate persistent levels of broadband, coherent radio emission, associated with the presence of kG magnetic fields in a large-scale, stable configuration. Compact sources located at the magnetic polar regions produce highly beamed emission generated by the electron cyclotron maser instability, the same mechanism known to generate planetary coherent radio emission in our solar system. The narrow beams of radiation pass our line of sight as the dwarf rotates, producing the associated periodic bursts. The resulting radio light curves are analogous to the periodic light curves associated with pulsar radio emission highlighting TVLM 513-46546 as the prototype of a new class of transient radio source.Comment: 12 pages, 3 figures, accepted for publication in ApJ Letter