4,515 research outputs found

    Analysis of cubic permutation polynomials for turbo codes

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    Quadratic permutation polynomials (QPPs) have been widely studied and used as interleavers in turbo codes. However, less attention has been given to cubic permutation polynomials (CPPs). This paper proves a theorem which states sufficient and necessary conditions for a cubic permutation polynomial to be a null permutation polynomial. The result is used to reduce the search complexity of CPP interleavers for short lengths (multiples of 8, between 40 and 352), by improving the distance spectrum over the set of polynomials with the largest spreading factor. The comparison with QPP interleavers is made in terms of search complexity and upper bounds of the bit error rate (BER) and frame error rate (FER) for AWGN and for independent fading Rayleigh channels. Cubic permutation polynomials leading to better performance than quadratic permutation polynomials are found for some lengths.Comment: accepted for publication to Wireless Personal Communications (19 pages, 4 figures, 5 tables). The final publication is available at springerlink.co

    Higher order approximation of isochrons

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    Phase reduction is a commonly used techinque for analyzing stable oscillators, particularly in studies concerning synchronization and phase lock of a network of oscillators. In a widely used numerical approach for obtaining phase reduction of a single oscillator, one needs to obtain the gradient of the phase function, which essentially provides a linear approximation of isochrons. In this paper, we extend the method for obtaining partial derivatives of the phase function to arbitrary order, providing higher order approximations of isochrons. In particular, our method in order 2 can be applied to the study of dynamics of a stable oscillator subjected to stochastic perturbations, a topic that will be discussed in a future paper. We use the Stuart-Landau oscillator to illustrate the method in order 2

    Pressure-induced enhancement of superconductivity and superconducting-superconducting transition in CaC_6\_6

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    We measured the electrical resistivity, ϱ(T)\varrho(T), of superconducting CaC_6\_6 at ambient and high pressure up to 16 GPa. For P≤P \leq8 GPa, we found a large increase of T_cT\_c with pressure from 11.5 up to 15.1 K. At 8 GPa, T_cT\_c drops and levels off at 5 K above 10 GPa. Correspondingly, the residual ϱ\varrho increases by ≈\approx 200 times and the ϱ(T)\varrho(T) behavior becomes flat. The recovery of the pristine behavior after depressurization is suggestive of a phase transition at 8 GPa between two superconducting phases with good and bad metallic properties, the latter with a lower T_cT\_c and more static disorder

    Dynamics of actin cables in polarized growth of the filamentous fungus Aspergillus nidulans

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    Highly polarized growth of filamentous fungi requires a continuous supply of proteins and lipids to the hyphal tip. This transport is managed by vesicle trafficking via the actin and microtubule cytoskeletons and their associated motor proteins. Particularly, actin cables originating from the hyphal tip are essential for hyphal growth. Although, specific marker proteins have been developed to visualize actin cables in filamentous fungi, the exact organization and dynamics of actin cables has remained elusive. Here, we observed actin cables using tropomyosin (TpmA) and Lifeact fused to fluorescent proteins in living Aspergillus nidulans hyphae and studied the dynamics and regulation. GFP tagged TpmA visualized dynamic actin cables formed from the hyphal tip with cycles of elongation and shrinkage. The elongation and shrinkage rates of actin cables were similar and approximately 0.6 μm/s. Comparison of actin markers revealed that high concentrations of Lifeact reduced actin dynamics. Simultaneous visualization of actin cables and microtubules suggests temporally and spatially coordinated polymerization and depolymerization between the two cytoskeletons. Our results provide new insights into the molecular mechanism of ordered polarized growth regulated by actin cables and microtubules

    Comparison of manual and semi-automated delineation of regions of interest for radioligand PET imaging analysis

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    BACKGROUND As imaging centers produce higher resolution research scans, the number of man-hours required to process regional data has become a major concern. Comparison of automated vs. manual methodology has not been reported for functional imaging. We explored validation of using automation to delineate regions of interest on positron emission tomography (PET) scans. The purpose of this study was to ascertain improvements in image processing time and reproducibility of a semi-automated brain region extraction (SABRE) method over manual delineation of regions of interest (ROIs). METHODS We compared 2 sets of partial volume corrected serotonin 1a receptor binding potentials (BPs) resulting from manual vs. semi-automated methods. BPs were obtained from subjects meeting consensus criteria for frontotemporal degeneration and from age- and gender-matched healthy controls. Two trained raters provided each set of data to conduct comparisons of inter-rater mean image processing time, rank order of BPs for 9 PET scans, intra- and inter-rater intraclass correlation coefficients (ICC), repeatability coefficients (RC), percentages of the average parameter value (RM%), and effect sizes of either method. RESULTS SABRE saved approximately 3 hours of processing time per PET subject over manual delineation (p 0.8) for both methods. RC and RM% were lower for the manual method across all ROIs, indicating less intra-rater variance across PET subjects' BPs. CONCLUSION SABRE demonstrated significant time savings and no significant difference in reproducibility over manual methods, justifying the use of SABRE in serotonin 1a receptor radioligand PET imaging analysis. This implies that semi-automated ROI delineation is a valid methodology for future PET imaging analysis

    Two dimensionality in quasi one-dimensional cobalt oxides

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    By means of muon spin rotation and relaxation (μ+\mu^+SR) techniques, we have investigated the magnetism of quasi one-dimensional (1D) cobalt oxides AEn+2AE_{n+2}Con+1_{n+1}O3n+3_{3n+3} (AEAE=Ca, Sr and Ba, nn=1, 2, 3, 5 and ∞\infty), in which the 1D CoO3_3 chain is surrounded by six equally spaced chains forming a triangular lattice in the abab-plane, using polycrystalline samples, from room temperature down to 1.8 K. For the compounds with nn=1 - 5, transverse field μ+\mu^+SR experiments showed the existence of a magnetic transition below ∼\sim100 K. The onset temperature of the transition (TconT_{\rm c}^{\rm on}) was found to decrease with nn; from 100 K for nn=1 to 60 K for nn=5. A damped muon spin oscillation was observed only in the sample with nn=1 (Ca3_3Co2_2O6_6), whereas only a fast relaxation obtained even at 1.8 K in the other three samples. In combination with the results of susceptibility measurements, this indicates that a two-dimensional short-range antiferromagnetic (AF) order appears below TconT_{\rm c}^{\rm on} for all compounds with nn=1 - 5; but quasi-static long-range AF order formed only in Ca3_3Co2_2O6_6, below 25 K. For BaCoO3_3 (nn=∞\infty), as TT decreased from 300 K, 1D ferromagnetic (F) order appeared below 53 K, and a sharp 2D AF transition occurred at 15 K.Comment: 12 pages, 14 figures, and 2 table

    Multicritical end-point of the first-order ferromagnetic transition in colossal magnetoresistive manganites

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    We have studied the bandwidth-temperature-magnetic field phase diagram of RE(0.55)Sr(0.45)MnO(3) colossal magnetoresistance manganites with ferromagnetic metallic (FM) ground state. The bandwidth (or equivalently the double exchange interaction) was controlled both via chemical substitution and hydrostatic pressure with a focus on the vicinity of the critical pressure p* where the character of the zero-field FM transition changes from first to second order. Below p* the first-order FM transition extends up to a critical magnetic field, H_cr. It is suppressed by pressure and approaches zero on the larger bandwidth side where the surface of the first-order FM phase boundary is terminated by a multicritical end-point (p*~32 kbar, T*~188 K, H*=0). The change in the character of the transition and the decrease of the CMR effect is attributed to the reduced CO/OO fluctuations.Comment: 4 pages, 4 figure

    Range-Separated Stochastic Resolution of Identity: Formulation and Application to Second Order Green's Function Theory

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    We develop a range-separated stochastic resolution of identity approach for the 44-index electron repulsion integrals, where the larger terms (above a predefined threshold) are treated using a deterministic resolution of identity and the remaining terms are treated using a stochastic resolution of identity. The approach is implemented within a second-order Greens function formalism with an improved O(N3)O(N^3) scaling with the size of the basis set, NN. Moreover, the range-separated approach greatly reduces the statistical error compared to the full stochastic version ({\it J. Chem. Phys.} {\bf 151}, 044144 (2019)), resulting in computational speedups of ground and excited state energies of nearly two orders of magnitude, as demonstrated for hydrogen dimer chains

    Superresolution microscopy reveals a dynamic picture of cell polarity maintenance during directional growth

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    Polar (directional) cell growth, a key cellular mechanism shared among a wide range of species, relies on targeted insertion of new material at specific locations of the plasma membrane. How these cell polarity sites are stably maintained during massive membrane insertion has remained elusive. Conventional live-cell optical microscopy fails to visualize polarity site formation in the crowded cell membrane environment because of its limited resolution. We have used advanced live-cell imaging techniques to directly observe the localization, assembly, and disassembly processes of cell polarity sites with high spatiotemporal resolution in a rapidly growing filamentous fungus, Aspergillus nidulans. We show that the membrane-associated polarity site marker TeaR is transported on microtubules along with secretory vesicles and forms a protein cluster at that point of the apical membrane where the plus end of the microtubule touches. There, a small patch of membrane is added through exocytosis, and the TeaR cluster gets quickly dispersed over the membrane. There is an incessant disassembly and reassembly of polarity sites at the growth zone, and each new polarity site locus is slightly offset from preceding ones. On the basis of our imaging results and computational modeling, we propose a transient polarity model that explains how cell polarity is stably maintained during highly active directional growth

    Superresolution and pulse-chase imaging reveal the role of vesicle transport in polar growth of fungal cells

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    Polarized growth of filamentous fungi requires continuous transport of biomolecules to the hyphal tip. To this end, construction materials are packaged in vesicles and transported by motor proteins along microtubules and actin filaments. We have studied these processes with quantitative superresolution localization microscopy of live Aspergillus nidulans cells expressing the photoconvertible protein mEosFPthermo fused to the chitin synthase ChsB. ChsB is mainly located at the Spitzenkörper near the hyphal tip and produces chitin, a key component of the cell wall. We have visualized the pulsatory dynamics of the Spitzenkörper, reflecting vesicle accumulation before exocytosis and their subsequent fusion with the apical plasma membrane. Furthermore, high-speed pulse-chase imaging after photoconversion of mEosFPthermo in a tightly focused spot revealed that ChsB is transported with two different speeds from the cell body to the hyphal tip and vice versa. Comparative analysis using motor protein deletion mutants allowed us to assign the fast movements (7 to 10 μm s−1) to transport of secretory vesicles by kinesin-1, and the slower ones (2 to 7 μm s−1) to transport by kinesin-3 on early endosomes. Our results show how motor proteins ensure the supply of vesicles to the hyphal tip, where temporally regulated exocytosis results in stepwise tip extension
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