1,353 research outputs found

    Hybrid carcinoma of the salivary gland: salivary duct adenocarcinoma adenoid cystic carcinoma

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73933/1/j.1365-2559.1999.00761.x.pd

    On monotonicity of dispute trees as explanations for case-based reasoning with abstract argumentation

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    Recent work on explainability raises the question of what different types of explanations actually mean. One idea is that explanations can reveal information about the behaviour of the model on a subset of the input space. When this way of interpreting explanations is thought as an interactive process, inferences from explanations can be seen as a form of reasoning. In the case of case-based reasoning with abstract argumentation (AA-CBR), previous work has used arbitrated dispute trees as a methodology for explanation. Those are dispute trees where nodes are seen as losing or winning depending on the outcome for the new case under consideration. In this work we show how arbitrated dispute trees can be readapted for different inputs, which allows a broader interpretation of them, capturing more of the input-output behaviour of the model. We show this readaptation is correct by construction, and thus the resulting reasoning based on this reuse is monotonic and thus necessarily a faithful explanation

    New simple digital self-calibration technique for pipeline ADCs using the internal thermal noise

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    IEEE International Symposium on Circuits and Systems, pp. 232 – 235, Seattle, EUAThis paper describes a new digital-domain selfcalibration technique for high-speed pipeline A/D converters using the internal thermal noise as input stimulus. This lowamplitude noise is amplified and recycled by the ADC itself and, due to the successive foldings, it is naturally converted into uniform noise. This noise is then used to calculate the required calibrating-codes. As an example, the calibration of a 13-bit pipeline ADC shows that the overall linearity can be significantly improved using this technique

    Detection of growth-related QTLs in turbot (Scophtalmus maximux)

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    Background The turbot (Scophthalmus maximus) is a highly appreciated European aquaculture species. Growth related traits constitute the main goal of the ongoing genetic breeding programs of this species. The recent construction of a consensus linkage map in this species has allowed the selection of a panel of 100 homogeneously distributed markers covering the 26 linkage groups (LG) suitable for QTL search. In this study we addressed the detection of QTL with effect on body weight, length and Fulton's condition factor. Results Eight families from two genetic breeding programs comprising 814 individuals were used to search for growth related QTL using the panel of microsatellites available for QTL screening. Two different approaches, maximum likelihood and regression interval mapping, were used in order to search for QTL. Up to eleven significant QTL were detected with both methods in at least one family: four for weight on LGs 5, 14, 15 and 16; five for length on LGs 5, 6, 12, 14 and 15; and two for Fulton's condition factor on LGs 3 and 16. In these LGs an association analysis was performed to ascertain the microsatellite marker with the highest apparent effect on the trait, in order to test the possibility of using them for marker assisted selection. Conclusions The use of regression interval mapping and maximum likelihood methods for QTL detection provided consistent results in many cases, although the high variation observed for traits mean among families made it difficult to evaluate QTL effects. Finer mapping of detected QTL, looking for tightly linked markers to the causative mutation, and comparative genomics are suggested to deepen in the analysis of QTL in turbot so they can be applied in marker assisted selection programs

    On the stability of nucleic acid feedback control systems

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    Recent work has shown how chemical reaction network theory may be used to design dynamical systems that can be implemented biologically in nucleic acid-based chemistry. While this has allowed the construction of advanced open-loop circuitry based on cascaded DNA strand displacement (DSD) reactions, little progress has so far been made in developing the requisite theoretical machinery to inform the systematic design of feedback controllers in this context. Here, we develop a number of foundational theoretical results on the equilibria, stability, and dynamics of nucleic acid controllers. In particular, we show that the implementation of feedback controllers using DSD reactions introduces additional nonlinear dynamics, even in the case of purely linear designs, e.g. PI controllers. By decomposing the effects of these non-observable nonlinear dynamics, we show that, in general, the stability of the linear system design does not necessarily imply the stability of the underlying chemical reaction network, which can be lost under experimental variability when feedback interconnections are introduced. We provide an in-depth theoretical analysis, and present an example to illustrate when the linear design does not capture the instability of the full nonlinear system implemented as a DSD reaction network, and we further confirm these results using Visual DSD, a bespoke software tool for simulating nucleic acid-based circuits. Our analysis highlights the many interesting and unique characteristics of this important new class of feedback control systems. (C) 2020 Elsevier Ltd. All rights reserved.11Nsciescopu

    Verifying compliance with ballast water standards : a decision-theoretic approach

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    We construct credible intervals to estimate the mean organism (zooplankton and phytoplankton) concentration in ballast water via a decision-theoretic approach. To obtain the required optimal sample size, we use a total cost minimization criterion defined as the sum of the sampling cost and the Bayes risk either under a Poisson or a negative binomial model for organism counts, both with a gamma prior distribution. Such credible intervals may be employed to verify whether the ballast water discharged from a ship is in compliance with international standards. We also conduct a simulation study to evaluate the credible interval lengths associated with the proposed optimal sample sizes

    Efficient digital self-calibration of video-rate pipeline ADCs using white gaussian noise

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    Proceedings of IEEE, ISCAS 2003, Vol.I, pp. 877-880A digital-domain self-calibration technique for video-rate pipeline A/D converters based on a white Gaussian noise input signal is presented. The implementation of the proposed algorithm requires simple digital circuitv. An application design example of the self-calibration of a IZb. 40 MUS CMOSpipeline ADC is shown to illustrate that the overall linearity of the ADC can be highly improved using this technique

    Estoque e produção de serapilheira sobre o solo em sistema agroflorestal sob influência de árvores de ingá (Ingá edulis) e cacau (Theobroma cacao) no município de Tomé-Açu (PA).

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    O objetivo do trabalho foi quantificar e comparar a variação temporal ao longo de quatro meses quanto ao acúmulo e produção de serapilheira de árvores de ingá e cacau em um sistema agroflorestal, situado no município de Tomé Açu - PA. A quantidade de serapilheira do solo foi estimada através de quadrantes de 0,5m X 0,5m. A produção de serapilheira foi estimada através da instalação de coletores com 1m2, suspenso a 15 cm do solo. O material foi coletado em sacos de papel, identificados e separados em frações (material lenhoso, não lenhoso e total) e em seguida secas em estufa de 65ºC por 48 horas e pesadas em balança digital com precisão de 0,01 g. O estoque e a produção de serapilheira se diferenciaram entre espécie, tempo e frações. Maiores resultados puderam ser observados na espécie de Ingá em relação à espécie de Cacau, em meses secos e com maior contribuição da fração não lenhosa
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