160 research outputs found
Fermi surface and quasiparticle dynamics of Na(x)CoO2 {x=0.7} investigated by Angle-Resolved Photoemission Spectroscopy
We present an angle-resolved photoemission study of Na0.7CoO2, the host
cobaltate of the NaxCoO2.yH2O series. Our results show a large hexagonal-like
hole-type Fermi surface, an extremely narrow strongly renormalized
quasiparticle band and a small Fermi velocity. Along the Gamma to M high
symmetry line, the quasiparticle band crosses the Fermi level from M toward
Gamma consistent with a negative sign of effective single-particle hopping (t
): t is estimated to be about 8 meV which is on the order of exchange coupling
J in this system. This suggests that t ~ J ~ 10 meV is an important energy
scale in the system. Quasiparticles are well defined only in the T-linear
resistivity regime. Small single particle hopping and unconventional
quasiparticle dynamics may have implications for understanding the unusual
behavior of this new class of compounds.Comment: Revised text, Added Figs, Submitted to PR
Role of deep levels and interface states in the capacitance characteristics of allâsputtered CuInSe2/CdS solar cell heterojunctions
Allâsputtered CuInSe2/CdS solar cellheterojunctions have been analyzed by means of capacitanceâfrequency (CâF) and capacitanceâbias voltage (CâV) measurements. Depending on the CuInSe2 layer composition, two kinds of heterojunctions were analyzed: type 1 heterojunctions (based on stoichiometric or slightly Inârich CuInSe2 layers) and type 2 heterojunctions (based on Cuârich CuInSe2 layers). In type 1 heterojunctions, a 80âmeV donor level has been found. Densities of interface states in the range 101 0â101 1 cm2âeVâ 1 (type 1) and in the range 101 2â101 3 cmâ 2âeVâ 1 (type 2) have been deduced. On the other hand, doping concentrations of 1.6Ă101 6 cmâ 3 for stoichiometric CuInSe2 (type 1 heterojunction) and 8Ă101 7 cmâ 3 for the CdS (type 2 heterojunction) have been deduced from CâVmeasurements
Rifampin pharmacokinetics in children, with and without human immunodeficiency virus infection, hospitalized for the management of severe forms of tuberculosis
<p>Abstract</p> <p>Background</p> <p>Rifampin is a key drug in antituberculosis chemotherapy because it rapidly kills the majority of bacilli in tuberculosis lesions, prevents relapse and thus enables 6-month short-course chemotherapy. Little is known about the pharmacokinetics of rifampin in children. The objective of this study was to evaluate the pharmacokinetics of rifampin in children with tuberculosis, both human immunodeficiency virus type-1-infected and human immunodeficiency virus-uninfected.</p> <p>Methods</p> <p>Fifty-four children, 21 human immunodeficiency virus-infected and 33 human immunodeficiency virus-uninfected, mean ages 3.73 and 4.05 years (<it>P </it>= 0.68), respectively, admitted to a tuberculosis hospital in Cape Town, South Africa with severe forms of tuberculosis were studied approximately 1 month and 4 months after commencing antituberculosis treatment. Blood specimens for analysis were drawn in the morning, 45 minutes, 1.5, 3.0, 4.0 and 6.0 hours after dosing. Rifampin concentrations were determined by liquid chromatography tandem mass spectrometry. For two sample comparisons of means, the Welch version of the t-test was used; associations between variables were examined by Pearson correlation and by multiple linear regression.</p> <p>Results</p> <p>The children received a mean rifampin dosage of 9.61 mg/kg (6.47 to 15.58) body weight at 1 month and 9.63 mg/kg (4.63 to 17.8) at 4 months after commencing treatment administered as part of a fixed-dose formulation designed for paediatric use. The mean rifampin area under the curve 0 to 6 hours after dosing was 14.9 and 18.1 ÎŒg/hour/ml (<it>P </it>= 0.25) 1 month after starting treatment in human immunodeficiency virus-infected and human immunodeficiency virus-uninfected children, respectively, and 16.52 and 17.94 ÎŒg/hour/ml (<it>P </it>= 0.59) after 4 months of treatment. The mean calculated 2-hour rifampin concentrations in these human immunodeficiency virus-infected and human immunodeficiency virus-uninfected children were 3.9 and 4.8 ÎŒg/ml (<it>P </it>= 0.20) at 1 month after the start of treatment and 4.0 and 4.6 ÎŒg/ml (<it>P </it>= 0.33) after 4 months of treatment. These values are considerably less than the suggested lower limit for 2-hour rifampin concentrations in adults of 8.0 ÎŒg/ml and even 4 ÎŒg/ml</p> <p>Conclusion</p> <p>Both human immunodeficiency virus-infected and human immunodeficiency virus-uninfected children with tuberculosis have very low rifampin serum concentrations after receiving standard rifampin dosages similar to those used in adults. Pharmacokinetic studies of higher dosages of rifampin are urgently needed in children to assist in placing the dosage of rifampin used in childhood on a more scientific foundation.</p
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Foreign policy and globalization theory: The case of Israel
Since the early 1990s, international relations has witnessed a stimulating debate on globalization. This debate laid the foundations for globalization theory (GT), providing the tools for an empirical examination of the globalization of multiple activities: from politics and organized violence, to finance, trade and production, through culture and environmental degradation. However, examination of what appear to be the best-known works on globalization reveals that foreign policy has been virtually excluded from GT. In this context, based on what is described here as a synergistic transformationalist approach (STA) to globalization, I provide a critique of GT. The critique is geared towards examining why foreign policy hitherto has been overlooked by contemporary GT. I expose the problems this generates and address them by exploring how STA enables GT to incorporate foreign policy. I use the case of Israel heuristically to elicit how incorporating foreign policy into GT may provide a better understanding of the relationship between foreign policy and globalization. Three themes are highlighted: the role of foreign policy in inducing and reproducing globalization; determining the mutually constitutive relationship between globalization and the state; and shaping the interfacing between international politics and globalization
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