Muonium hyperfine structure and hadronic effects

A new result for the hadronic vacuum polarization correction to the muonium hyperfine splitting (HFS) is presented: Delta nu(had - vp) = (0.233 +- 0.003) kHz. Compared with previous calculations, the accuracy is improved by using the latest data on e+e- -> hadrons. The status of the QED prediction for HFS is discussed

Self-generated Self-similar Traffic

Self-similarity in the network traffic has been studied from several aspects: both at the user side and at the network side there are many sources of the long range dependence. Recently some dynamical origins are also identified: the TCP adaptive congestion avoidance algorithm itself can produce chaotic and long range dependent throughput behavior, if the loss rate is very high. In this paper we show that there is a close connection between the static and dynamic origins of self-similarity: parallel TCPs can generate the self-similarity themselves, they can introduce heavily fluctuations into the background traffic and produce high effective loss rate causing a long range dependent TCP flow, however, the dropped packet ratio is low.Comment: 8 pages, 12 Postscript figures, accepted in Nonlinear Phenomena in Complex System

Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation.

Atherosclerosis impacts arteries where disturbed blood flow renders the endothelium susceptible to inflammation. Cytokine activation of endothelial cells (EC) upregulates VCAM-1 receptors that target monocyte recruitment to atherosusceptible regions. Endoplasmic reticulum (ER) stress elicits EC dysregulation in metabolic syndrome. We hypothesized that ER plays a central role in mechanosensing of atherosusceptible shear stress (SS) by signaling enhanced inflammation. Aortic EC were stimulated with low-dose TNFα (0.3 ng/ml) in a microfluidic channel that produced a linear SS gradient over a 20mm field ranging from 0-16 dynes/cm2. High-resolution imaging of immunofluorescence along the monolayer provided a continuous spatial metric of EC orientation, markers of ER stress, VCAM-1 and ICAM-1 expression, and monocyte recruitment. VCAM-1 peaked at 2 dynes/cm2 and decreased to below static TNFα-stimulated levels at atheroprotective-SS of 12 dynes/cm2, whereas ICAM-1 rose to a maximum in parallel with SS. ER expansion and activation of the unfolded protein response also peaked at 2 dynes/cm2, where IRF-1-regulated VCAM-1 expression and monocyte recruitment also rose to a maximum. Silencing of PECAM-1 or key ER stress genes abrogated SS regulation of VCAM-1 transcription and monocyte recruitment. We report a novel role for ER stress in mechanoregulation at arterial regions of atherosusceptible-SS inflamed by low-dose TNFα

Electronic spin precession and interferometry from spin-orbital entanglement in a double quantum dot

A double quantum dot inserted in parallel between two metallic leads allows to entangle the electron spin with the orbital (dot index) degree of freedom. An Aharonov-Bohm orbital phase can then be transferred to the spinor wavefunction, providing a geometrical control of the spin precession around a fixed magnetic field. A fully coherent behaviour is obtained in a mixed orbital/spin Kondo regime. Evidence for the spin precession can be obtained, either using spin-polarized metallic leads or by placing the double dot in one branch of a metallic loop.Comment: Final versio

Transport properties of a molecule embedded in an Aharonov-Bohm interferometer

We theoretically investigate the transport properties of a molecule embedded in one arm of a mesoscopic Aharonov-Bohm interferometer. Due to the presence of phonons the molecule level position ($\epsilon_d$) and the electron-electron interaction ($U$) undergo a \emph{polaronic shift} which affects dramatically the electronic transport through the molecular junction. When the electron-phonon interaction is weak the linear conductance presents Fano-line shapes as long as the direct channel between the electrodes is opened. The observed Fano resonances in the linear conductance are originated from the interference between the spin Kondo state and the direct path. For strong enough electron-phonon interaction, the electron-electron interaction is renormalized towards negative values, {\it i.e.} becomes effectively attractive. This scenario favors fluctuations between the empty and doubly occupied charge states and therefore promotes a charge Kondo effect. However, the direct path between the contacts breaks the electron-hole symmetry which can efficiently suppress this charge Kondo effect. Nevertheless, we show that a proper tuning of the gate voltage is able to revive the Kondo resonance. Our results are obtained by using the Numerical Renormalization approximation to compute the electronic spectral function and the linear conductance.Comment: 17 pages, 12 figure

The GL 569 Multiple System

We report the results of high spectral and angular resolution infrared observations of the multiple system GL 569 A and B that were intended to measure the dynamical masses of the brown dwarf binary believed to comprise GL 569 B. Our analysis did not yield this result but, instead, revealed two surprises. First, at age ~100 Myr, the system is younger than had been reported earlier. Second, our spectroscopic and photometric results provide support for earlier indications that GL 569 B is actually a hierarchical brown dwarf triple rather than a binary. Our results suggest that the three components of GL 569 B have roughly equal mass, ~0.04 Msun.Comment: 29 pages, 10 figures, accepted for publication in the Astrophysical Journal; minor corrections to Section 5.1; changed typo in 6.

Spinful Composite Fermions in a Negative Effective Field

In this paper we study fractional quantum Hall composite fermion wavefunctions at filling fractions \nu = 2/3, 3/5, and 4/7. At each of these filling fractions, there are several possible wavefunctions with different spin polarizations, depending on how many spin-up or spin-down composite fermion Landau levels are occupied. We calculate the energy of the possible composite fermion wavefunctions and we predict transitions between ground states of different spin polarizations as the ratio of Zeeman energy to Coulomb energy is varied. Previously, several experiments have observed such transitions between states of differing spin polarization and we make direct comparison of our predictions to these experiments. For more detailed comparison between theory and experiment, we also include finite-thickness effects in our calculations. We find reasonable qualitative agreement between the experiments and composite fermion theory. Finally, we consider composite fermion states at filling factors \nu = 2+2/3, 2+3/5, and 2+4/7. The latter two cases we predict to be spin polarized even at zero Zeeman energy.Comment: 17 pages, 5 figures, 4 tables. (revision: incorporated referee suggestions, note added, updated references

Gz, a guanine nucleotide-binding protein with unique biochemical properties

Cloning of a complementary DNA (cDNA) for Gz alpha, a newly appreciated member of the family of guanine nucleotide-binding regulatory proteins (G proteins), has allowed preparation of specific antisera to identify the protein in tissues and to assay it during purification from bovine brain. Additionally, expression of the cDNA in Escherichia coli has resulted in the production and purification of the recombinant protein. Purification of Gz from bovine brain is tedious, and only small quantities of protein have been obtained. The protein copurifies with the beta gamma subunit complex common to other G proteins; another 26- kDa GTP-binding protein is also present in these preparations. The purified protein could not serve as a substrate for NAD-dependent ADP- ribosylation catalyzed by either pertussis toxin or cholera toxin. Purification of recombinant Gz alpha (rGz alpha) from E. coli is simple, and quantities of homogeneous protein sufficient for biochemical analysis are obtained. Purified rGz alpha has several properties that distinguish it from other G protein alpha subunit polypeptides. These include a very slow rate of guanine nucleotide exchange (k = 0.02 min^-1), which is reduced greater than 20-fold in the presence of mM concentrations of Mg2+. In addition, the rate of the intrinsic GTPase activity of Gz alpha is extremely slow. The hydrolysis rate (kcat) for rGz alpha at 30 degrees C is 0.05 min^-1, or 200-fold slower than that determined for other G protein alpha subunits. rGz alpha can interact with bovine brain beta gamma but does not serve as a substrate for ADP-ribosylation catalyzed by either pertussis toxin or cholera toxin. These studies suggest that Gz may play a role in signal transduction pathways that are mechanistically distinct from those controlled by the other members of the G protein family