Genesis 2–3 and Alcibiades’s speech in Plato’s Symposium: A cultural critical reading

The purpose of this article is to discuss some basic problems and methodological steps concerning the encounter between Hebrews and Greeks in the Classical period and its impact on the Hellenistic era. The relationship between the Old Testament and Ancient Greek literature will be examined on the basis of Genesis 2–3 and Alcibiades’s speech in Plato’s Symposium (212c–223d). The following considerations and models of interpretation can arise from the analysis of Alcibiades’s speech compared to M- and LXX-Genesis 2–3: (1) Ancient Greek writers were familiar with Old Testament oral or written traditions through improvised translations. They prepared the way for the LXX and, in their compositions, were in dispute with them although they do not make specific references to the Hebrews and their literature; (2) Hebrew authors knew the works of Ancient Greek authors and used Greek philosophical terminology which they creatively adapted to Semitic models; (3) Both models are possible. One should not rush to any decisions but examine each case individually, in the original language

Chapter Unraveling Stakeholders’ Discourses Regarding Sustainable Development and Biodiversity Conservation in Greece

Pharmacolog

Euripides’s Helena and Pentateuch traditions: The Septuagint from the perspective of Ancient Greek Tragedies

In some cases discussed below, the present form of the Septuagint is not representative of how Ancient Greek Tragedies were received by the LXX translators, but of how Old Testament traditions in Greek form were received by the tragedians

Investigating the barriers to adopting a 'human-in-nature' view in Greek biodiversity conservation

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The role of CaMKII regulation of phospholamban activity in heart disease

Phospholamban (PLN) is a phosphoprotein in cardiac sarcoplasmic reticulum (SR) that is a reversible regulator of the Ca(2)(+)-ATPase (SERCA2a) activity and cardiac contractility. Dephosphorylated PLN inhibits SERCA2a and PLN phosphorylation, at either Ser(16) by PKA or Thr(17) by Ca(2)(+)-calmodulin-dependent protein kinase (CaMKII), reverses this inhibition. Through this mechanism, PLN is a key modulator of SR Ca(2)(+) uptake, Ca(2)(+) load, contractility, and relaxation. PLN phosphorylation is also the main determinant of β1-adrenergic responses in the heart. Although phosphorylation of Thr(17) by CaMKII contributes to this effect, its role is subordinate to the PKA-dependent increase in cytosolic Ca(2)(+), necessary to activate CaMKII. Furthermore, the effects of PLN and its phosphorylation on cardiac function are subject to additional regulation by its interacting partners, the anti-apoptotic HAX-1 protein and Gm or the anchoring unit of protein phosphatase 1. Regulation of PLN activity by this multimeric complex becomes even more important in pathological conditions, characterized by aberrant Ca(2)(+)-cycling. In this scenario, CaMKII-dependent PLN phosphorylation has been associated with protective effects in both acidosis and ischemia/reperfusion. However, the beneficial effects of increasing SR Ca(2)(+) uptake through PLN phosphorylation may be lost or even become deleterious, when these occur in association with alterations in SR Ca(2)(+) leak. Moreover, a major characteristic in human and experimental heart failure (HF) is depressed SR Ca(2)(+) uptake, associated with decreased SERCA2a levels and dephosphorylation of PLN, leading to decreased SR Ca(2)(+) load and impaired contractility. Thus, the strategy of altering SERCA2a and/or PLN levels or activity to restore perturbed SR Ca(2)(+) uptake is a potential therapeutic tool for HF treatment. We will review here the role of CaMKII-dependent phosphorylation of PLN at Thr(17) on cardiac function under physiological and pathological conditions

“Not in their right mind”: the relation of psychopathology to the quantity and quality of creative thought

This is the published version. Copyright 2014 FrontierThe empirical link between psychopathology and creativity is often correlational and fraught with suspiciously causal interpretations. In this paper, we review research in favor of the position that certain forms of psychopathology that profoundly affect the neural substrates for rule-based thought (e.g., schizophrenia, bipolar disorder) can significantly influence the quantity of creative production. Because highly productive individuals, irrespective of psychopathology, often produce work of greater quality, it seems that such an increase in the quantity of one’s output positively affects the likelihood of generating those statistically rare acts and achievements identified and celebrated as creative. We consider evidence that offers support for such a claim. In addition, we explore findings from neuroscience that can address how a neural mechanism, the flexibility of which relies on tradeoffs between rule-based (e.g., prefrontal cortex) and stimulus-based (e.g., sensorimotor cortex) brain regions, is influenced by psychopathology in ways that can alter dramatically the quantity and quality of creative output

Emotion Regulation Flexibility: Gender Differences in Context Sensitivity and Repertoire

This work is licensed under a Creative Commons Attribution 4.0 International License.Emotion regulation (ER) has been conceptualized as processes through which individuals modulate their emotions consciously and non-consciously to respond appropriately to environmental demands. Emotions can be regulated in many ways and specific strategies may have differing efficacy across situations and individuals. The importance of flexibility in implementing ER strategies has been highlighted in many current models. In this study, we investigated gender differences in two regulatory processes, context sensitivity and repertoire using a novel coding system for ER strategy classification. The results revealed that women consistently used more strategies than men and were more flexible in the implementation of those strategies. These findings validate our novel coding system for ER strategy classification. They further highlight the importance of a comprehensive examination of gender differences in ER processes for understanding the nuances of ER and developing effective treatments for psychopathologies characterized by ER deficits.National Science Foundation Graduate Research Fellowship (1451148)Brain and Behavior Research Foundation Young Investigator Award (23980

COMMUNICATION AND PUBLICITY: THE LAST HOPE FOR ADDRESSING INTERNAL VIOLENCE AGAINST REFUGEE AND IMMIGRANT WOMEN'S STAYING IN CAMPS

With no doubt, all refugees and immigrants staying in camps are suffering for many reasons. Every individual who lives in camps under poverty and stressful situation everywhere on earth is suffering. This is something that happens in Greek camps as well. Among individuals who stay at camps women experience the greatest danger. They are at great risk as they may be victims of rapes, as they stay for hours alone at containers looking after the "housekeeping" and children nurturing, as they live in fear and danger for many reasons. Within this framework, communication and publicity of hazard situation that exists in the camps is considered the last hope for addressing internal violence against refugee and immigrant women’s staying there. Communication and publicity of the particular problem may wake up those who are responsible for this situation and the defense of human rights. They have to do all necessary for the sooner and best resolution of this mess.  Article visualizations