1,531 research outputs found

    Getting Past the “Entrepreneurial Growth Ceiling”: A Longitudinal Study of IPO Firm Growth Through Solution Driven Strategies

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    In this paper we introduce a concept that we call the Entrepreneurial Growth Ceiling (EGC). We develop arguments that new venture IPOs hit the EGC prior to their IPO, and the ceiling is part of the impetus for going public. The EGC represents a set of problems, and we hypothesize that a firm’s ability to break through the ceiling quickly (within a year following the IPO) is critical for long-term performance. We argue that proceeds from the IPO will aid firms in breaking through the ceiling if the proceeds are strategically allocated. Results indicate firms that allocate proceeds to human resources and research and development (R&D) resources are more likely to break through the EGC quickly and enhance long-term stock performance

    Inhibition of gap junction and adherens junction assembly by connexin and A-CAM antibodies

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    We examined the roles of the extracellular domains of a gap junction protein and a cell adhesion molecule in gap junction and adherens junction formation by altering cell interactions with antibody Fab fragments. Using immunoblotting and immunocytochemistry we demonstrated that Novikoff cells contained the gap junction protein, connexin43 (Cx43), and the cell adhesion molecule, A-CAM (N-cadherin). Cells were dissociated in EDTA, allowed to recover, and reaggregated for 60 min in media containing Fab fragments prepared from a number of antibodies. We observed no cell-cell dye transfer 4 min after microinjection in 90% of the cell pairs treated with Fab fragments of antibodies for the first or second extracellular domain of Cx43, the second extracellular domain of connexin32 (Cx32) or A-CAM. Cell-cell dye transfer was detected within 30 s in cell pairs treated with control Fab fragments (pre-immune serum, antibodies to the rat major histocompatibility complex or the amino or carboxyl termii of Cx43). We observed no gap junctions by freeze-fracture EM and no adherens junctions by thin section EM between cells treated with the Fab fragments that blocked cell-cell dye transfer. Gap junctions were found on approximately 50% of the cells in control samples using freeze-fracture EM. We demonstrated with reaggregated Novikoff cells that: (a) functional interactions of the extracellular domains of the connexins were necessary for the formation of gap junction channels; (b) cell interactions mediated by A-CAM were required for gap junction assembly; and (c) Fab fragments of antibodies for A-CAM or connexin extracellular domains blocked adherens junction formation

    Buffalo National River Ecosystems - Part II

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    The priorities were established for the Buffalo National River Ecosystem Studies through meetings and correspondence with Mr. Roland Wauer and other personnel of the Office of Natural Sciences, Southwest Region of the National Park Service. These priorities were set forth in the appendix of contract no. CX 700050443 dated May 21, 1975

    Modeling Dust and Starlight in Galaxies Observed by Spitzer and Herschel: NGC 628 and NGC 6946

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    We characterize the dust in NGC628 and NGC6946, two nearby spiral galaxies in the KINGFISH sample. With data from 3.6um to 500um, dust models are strongly constrained. Using the Draine & Li (2007) dust model, (amorphous silicate and carbonaceous grains), for each pixel in each galaxy we estimate (1) dust mass surface density, (2) dust mass fraction contributed by polycyclic aromatic hydrocarbons (PAH)s, (3) distribution of starlight intensities heating the dust, (4) total infrared (IR) luminosity emitted by the dust, and (5) IR luminosity originating in regions with high starlight intensity. We obtain maps for the dust properties, which trace the spiral structure of the galaxies. The dust models successfully reproduce the observed global and resolved spectral energy distributions (SEDs). The overall dust/H mass ratio is estimated to be 0.0082+/-0.0017 for NGC628, and 0.0063+/-0.0009 for NGC6946, consistent with what is expected for galaxies of near-solar metallicity. Our derived dust masses are larger (by up to a factor 3) than estimates based on single-temperature modified blackbody fits. We show that the SED fits are significantly improved if the starlight intensity distribution includes a (single intensity) "delta function" component. We find no evidence for significant masses of cold dust T<12K. Discrepancies between PACS and MIPS photometry in both low and high surface brightness areas result in large uncertainties when the modeling is done at PACS resolutions, in which case SPIRE, MIPS70 and MIPS160 data cannot be used. We recommend against attempting to model dust at the angular resolution of PACS.Comment: To be published in Apj, September 2012. See the full version at http://www.astro.princeton.edu/~ganiano/Papers

    Final Report Buffalo National River Ecosystems Part IV

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    Sampling point locations and analytical procedures remained unchanged from those outlined in previous Buffalo National River Ecosystem reports. The only significant change in analytical procedures was a reversion to the glass fiber filter method for collection and extraction of samples for chlorophyll analysis. This change was neeessitated by a need for filtering a larger volume to obtain enough chlorophyll for an accurate measurement. Samples were collected monthly from April 9 through December 30. No samples were taken in January or February due to the extremely uncertain traveling conditions caused by the frequent snows. Prior research indicates that the December 30 sample is sufficiently reflective of stable winter conditions to obviate the need for more winter samples (see previous reports)

    Buffalo National River Ecosystem - Part III

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    Samples for water quality analyses and phycological studies were taken from the nine standard sampling locations on the Buffalo River nine times during the period from March 1976 through February 1977. The April-June 1976 samples represent nearly identical conditions throughout the spring period; therefore, emphasis was placed on taxonomic research. As the early January sample was considered sufficient~y reflective of stable winter conditions, the December and February periods were. used for detailed microscopic examination of the rich and diverse diatom flora that was found in the river this year. A total of 273 taxa of diatoms were identified from the 75 samples collected, including 123 new additions to the diatom flora of the Buffalo River. Details of this study, including the breakdown of many species into varieties, will be presented in a separate paper. A list of the new species found and a general discussion are included in this report

    The opaque nascent starburst in NGC 1377: Spitzer SINGS observations

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    We analyze extensive data on NGC 1377 from the Spitzer Infrared Nearby Galaxies Survey (SINGS). Within the category of nascent starbursts that we previously selected as having infrared-to-radio continuum ratios in large excess of the average and containing hot dust, NGC 1377 has the largest infrared excess yet measured. Optical imaging reveals a morphological distortion suggestive of a recent accretion event. Infrared spectroscopy reveals a compact and opaque source dominated by a hot, self-absorbed continuum (Ď„~ 20 in the 10ÎĽm silicate band). We provide physical evidence against nonstellar activity being the heating source. H II regions are detected through the single [Ne II] line, probing 85% of ionizing photons are suppressed by dust. The only other detected emission features are molecular hydrogen lines, arguably excited mainly by shocks, besides photodissociation regions, and weak aromatic bands. The new observations support our interpretation in terms of an extremely young starburst (<1 Myr). More generally, galaxies deficient in radio synchrotron emission are likely observed within a few Myr of the onset of a starburst and after a long quiescence, prior to the replenishment of the interstellar medium with cosmic rays. The similar infrared-radio properties of NGC 1377 and some infrared-luminous galaxies suggest that NGC 1377 constitutes an archetype that will be useful to better understand starburst evolution. Although rare locally because observed in a brief evolutionary stage, nascent starbursts may represent a nonnegligible fraction of merger-induced starbursts that dominate deep infrared counts. Since they differ dramatically from usual starburst templates, they have important consequences for the interpretation of deep surveys

    Preliminary Reconnaissance Water Quality Survey of the Buffalo National River

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    In accordance with Contract No. CX 700030105, dated 12 February 1973, the University of Arkansas , Water Resources Resear ch Center is submitting a Preliminary Reconnaissance Water Quality Survey of the Buffalo National River. The Water Resources Research Center of Arkansas has supplied the necessary personnel and facil ities to perform a preliminary reconnaissance survey of the Buffalo National River of Arkansas with special emphasis placed on the establishment of both permanent and temporary benchmarks for water quality sampling. Preliminary water quality samples have been collected to make those chemical, physical, and biological analyses as defined by Mr . Roland H. Wauer and other Park Service personnel on 3 May 1973

    A Study of Heating and Cooling of the ISM in NGC 1097 with Herschel-PACS and Spitzer-IRS

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    NGC 1097 is a nearby Seyfert 1 galaxy with a bright circumnuclear starburst ring, a strong large-scale bar and an active nucleus. We present a detailed study of the spatial variation of the far infrared (FIR) [CII]158um and [OI]63um lines and mid-infrared H2 emission lines as tracers of gas cooling, and of the polycyclic aromatic hydrocarbon (PAH) bands as tracers of the photoelectric heating, using Herschel-PACS, and Spitzer-IRS infrared spectral maps. We focus on the nucleus and the ring, and two star forming regions (Enuc N and Enuc S). We estimated a photoelectric gas heating efficiency ([CII]158um+[OI]63um)/PAH in the ring about 50% lower than in Enuc N and S. The average 11.3/7.7um PAH ratio is also lower in the ring, which may suggest a larger fraction of ionized PAHs, but no clear correlation with [CII]158{\mu}m/PAH(5.5 - 14um) is found. PAHs in the ring are responsible for a factor of two more [CII]158um and [OI]63um emission per unit mass than PAHs in the Enuc S. SED modeling indicates that at most 25% of the FIR power in the ring and Enuc S can come from high intensity photodissociation regions (PDRs), in which case G0 ~ 10^2.3 and nH ~ 10^3.5 cm^-3 in the ring. For these values of G0 and nH PDR models cannot reproduce the observed H2 emission. Much of the the H2 emission in the starburst ring could come from warm regions in the diffuse ISM that are heated by turbulent dissipation or shocks.Comment: 17 pages, 14 figures, 5 tables; accepted for publication in Ap

    The Calibration of Mid-Infrared Star Formation Rate Indicators

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    With the goal of investigating the degree to which the mid-infrared emission traces the star formation rate (SFR), we analyze Spitzer 8 um and 24 um data of star-forming regions in a sample of 33 nearby galaxies with available HST/NICMOS images in the Paschen-alpha (1.8756 um) emission line. The galaxies are drawn from the Spitzer Infrared Nearby Galaxies Survey (SINGS) sample, and cover a range of morphologies and a factor ~10 in oxygen abundance. Published data on local low-metallicity starburst galaxies and Luminous Infrared Galaxies are also included in the analysis. Both the stellar-continuum-subtracted 8 um emission and the 24 um emission correlate with the extinction-corrected Pa-alpha line emission, although neither relationship is linear. Simple models of stellar populations and dust extinction and emission are able to reproduce the observed non-linear trend of the 24 um emission versus number of ionizing photons, including the modest deficiency of 24 um emission in the low metallicity regions, which results from a combination of decreasing dust opacity and dust temperature at low luminosities. Conversely, the trend of the 8 um emission as a function of the number of ionizing photons is not well reproduced by the same models. The 8 um emission is contributed, in larger measure than the 24 um emission, by dust heated by non-ionizing stellar populations, in agreement with previous findings. Two SFR calibrations, one using the 24 um emission and the other using a combination of the 24 um and H-alpha luminosities (Kennicutt et al. 2007), are presented. No calibration is presented for the 8 um emission, because of its significant dependence on both metallicity and environment. The calibrations presented here should be directly applicable to systems dominated by on-going star formation.Comment: 67 pages, 15 figures, accepted for publication on the Astrophysical Journal; replacement contains: correction to equation 8; important tweaks to equation 9; various typos correcte
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