Frontostriatal deficit in Motor Neuron Disease/Amyotrophic Lateral Sclerosis (MND/ALS)

So far, cognitive derangements in MND/ALS have not been widely studied. Nevertheless, it seems that in subgroups of patients cognitive functions are impaired in different degree, so that often at least two sub-types of the syndrome are reported: Motor Neuron Disease/Amyotrophic Lateral Sclerosis/Dementia Syndrome (MND/ALS/DS) and Motor Neuron Disease/Amyotrophic Lateral Sclerosis/ Aphasia Syndrome (MND/ALS/AS. A third subtype showing both symptoms of cognitive impairment may be identified in subgroups of patients and denominated Motor Neuron Disease/Amyotrophic Lateral Sclerosis/Dementia-Aphasia Syndrome (MND/ALS/DAS). Frontostriatal system is reported as a network heavily damaged in MND/ALS/DS, MND/ALS/AS, MND/ALS/DAS. The system is plausibly responsible of motor skills and verbs production, hence to become aware of a possible frontostriatal deficit in subgroup of MND/ALS patients might consent us to link at the brain level (motor) action and verbs and possibly ideomotor praxia and verbs. We have used Goal-Oriented Perception Task (GOPT) and Action Fluency Task (AFT) in order to detect with some accuracy impairments related to gestaltic analysis directed toward a goal, and verb retrieval deficits possibly underlying executive system dysfunction that destabilizes the ability to mentally coordinate the information associated with a verb. These tests should consent to detect possible frontostriatal derangements. We have tested 10 MND/ALS patients and 10 healthy subjects matched fore age, sex and laterality. AFT showed that 3 out of 6 patients are heavily impaired in this test (6.3 (mean) verbs generated vs 13.3 of the control group). GOPT detected a remarkable impairment in all patients: p=0.0021 (grammatical side), p=0.0002 (perceptual side). Reported frontostriatal deficit in MND/ALS seems confirmed by this study, and probably it is more easily detected by GOPT than by AFT

Classification of Acute Leukemia using Fuzzy Neural Networks

Accurate classification of cancers based on microarray gene expressions is very important for doctors to choose a proper treatment. In this paper, we compared ten filter based gene selection methods in order to differentiate acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) in leukemia dataset. Dimensionality reduction methods, such as Spearman Correlation Coefficient and Wilcoxon Rank Sum Statistics are used for gene selection. The experimental results showed that the proposed gene selection methods are efficient, effective, and robust in identifying differentially expressed genes. Adopting the existing SVM-based and KNN-based classifiers, the selected genes by filter based methods in general give more accurate classification results, typically when the sample class sizes in the training dataset are unbalanced

A Study on Information Seeking Behavior of the Medical and Allied College Students in Goa State

This paper attempts to explore the information seeking behavior of medical, dental, nursing, pharmacy and homeopathic colleges in goa state. The purpose of the study is to know the awareness and use of reference sources available in the library and to know the preference of media as a source of information for their requirement. Results found that, still 95 percent respondents refer/depend upon printed books for their information needs. Only 49 percent students are happy with the internet and online resources available in their college libraries. Further researcher suggested that, the library orientation has to be conducted regularly to convert another 30 percent students to make use of their college library by giving more importance to electronic sources and services

A STUDY ON USE OF FACEBOOK BY PG STUDENTS OF SELECTED DEPARTMENTS IN SRI RAMAKRISNA COLLEGE OF ARTS AND SCIENCE, COIMBATORE

The study on use of face book by students is a paper that represents a evaluation of more than one hundred studies on the social networking website face book. The paper focuses on face book use, which is currently the most researched theme the main studies for each group are presented, with an emphasis on the most influential ones in the field. The focus of this fictional examination is on the commonalities and difference that start from the results. As a result, one could notice that face book is mainly used to keep in touch with other people, but not in a conventional way as uses tend to spy on other users profiles this phenomenon leads to a growing exhibitionism, which is in turn related to individuals personality teats .use of face book is also influenced by peers and experience with the website

Research Contributions of SAARC Countries in Social Science: A Bibliometric Study

SCI mago is the Journal and Country Ranking database available freely on the internet. We have accessed the required data from 2008 to 2017 from this database and evaluated the research productivity of SAARC countries and citations in the field of social science subject. This article studied SAARC countries publications, citations, citations per document, self-citations and degree of self – citations. The study revealed that on an average 6054 articles are published during the study period. India is the only country to publish more than the average citations publications during the ten years of study. India received 78% of citations and stood 1st rank in the study, whereas Pakistan and Bangladesh got 8% and 6% citations and stood 2nd and 3rd rank. Nepal got highest 76% of citations per document and stood 1st rank among the SAARC countries in the last ten years from 2008 to 2017. Further, it is found that the degree of self-citation is 0.24, which is very lowest. Since all the SAARC countries are underdeveloped so it is suggested that the government of SAARC countries has to encourage more and more publications, then only their socio-economic level may increase. Individuals, as well as organisations, should take more interest to publish their research articles in high impact journals both at national and international level

A Compartive Clinical Study of therapeautic effect of Rambana Rasa with and without Eranda Sneha in Amavata w.s.r. Rheumatoid Arthritis

Amavata is the most challenging disease for the medical science, as it causes severe intolerable pain and severe deformities making the patient disable and bed ridden. As it is the disease of Rasavaha Srotas and having several features similar to Rheumatoid Arthrtis, Amavata can be co-related with Rheumatoid Arthritis (RA). Ama and vitiated Vata play dominant role, though all Dosha take part in the causation of the disease, Amavata is the outcome of Agnidushti, Amotpatti and Sandhivikruti, with the passage of the time most of the dietary habits, changing lifestyle and environment have been contributing to the disease, the risk factor include age, gender, genetics and environmental exposure. Worldwide, the annual incidence of RA is approximately 1%, increasing with age and peaking between the age of 35 and 50 years. So, patients are continuously looking for the treatment from Ayurveda to overcome this challenge. Ramban Rasa is unique formulation which is favorable in the management of the Amavata, as mentioned by Yogratnakar, Bhaishajya Ratnawali, Bhav Prakash and other classical text

Mahasweta Devi’s Bitter Soil: An Ecocritical Perspective

This research article critically examines Mahasweta Devi as an Environmental crusader with special reference to Bitter Soil. It is a set of four short stories that is, “Little Ones”, “Seeds”, “Witch”, and “Salt”. These stories focus on the injustice done to the environment and to its environs. The first story “Little Ones” revolves around how the mainstream people exploit the environment and the Aghariya tribes in Lohri. The second story “Seed” set around Kuruda village. It deals with two themes; one is the exploitation of field labourers by not giving them a proper wage and the second is the exploitation by offering uncultivable land to the tribes in the name of ‘Budhanodyamam’. The third story “Witch” delineates the concept of daini in the villages of Hesadi and Murhai and the ecological imbalance in those villages. The fourth story in the collection is “Salt”. As the title suggests, the story revolves around the importance of salt

Cultural Diversity among the Employees and its Effect in Organizational Climate

Cultural diversity is a group of diverse individuals from different cultures or societies. The study is conducted to explore how manage workforce diversity and its consequences to the company’s existence as well as examine how companies’ deal with challenges that comes with employees from diverse cultural backgrounds. The study describe diversity challenges that can affect the working climate and conflict between the employees through the diversity .The result shows that cultural diversity plays an effective role in some companies however inadequate mentoring and guidance could cause a company low productivity. For this reason there is must be regular improvement in ways to effectively manage a cultural diverse in workforce as the world keeps advancing

Handwritten Script Recognition using DCT, Gabor Filter and Wavelet Features at Line Level

In a country like India where more number of scripts are in use, automatic identification of printed and handwritten script facilitates many important applications including sorting of document images and searching online archives of document images. In this paper, a multiple feature based approach is presented to identify the script type of the collection of handwritten documents. Eight popular Indian scripts are considered here. Features are extracted using Gabor filters, Discrete Cosine Transform, and Wavelets of Daubechies family. Experiments are performed to test the recognition accuracy of the proposed system at line level for bilingual scripts and later extended to trilingual scripts. We have obtained 100% recognition accuracy for bi-scripts at line level. The classification is done using k-nearest neighbour classifier

Clinical evaluation of the effect of Khanda Kushmanda Avaleha in Rakta Pradara (Abnormal uterine bleeding)

Background: Raktapradara manifesting as excessive bleeding per vagina is seen to be an age old disease known to mankind since the era of Veda and Purana. Excessive and irregular menstrual bleeding condition is similar to Raktapradara a gynaecological condition mentioned in Ayurvedic classics. Rakta Pradara is one among the Rakta Pradoshaja Vikara and characterized by Artava Ati Pravrutti, Deerga Kala Pravrutti, Anruta Kala Pravrutti, Daha in Adho Vankshana Pradesha, Sroni, Prushta and Kukshi, Shoola in Garbhashaya, Angamardha etc. Objectives: To clinically evaluate the effect of Khanda Kushmanda Avaleha in Raktapradara. Materials and Methods: The patients attending the O.P.D. and I.P.D. of S.V.M Ayurvedic Medical College and PG Centre, Ilkal, were randomly divided into 2 groups, Group A was treated with Khanda Kusmanda Avaleha and Group B was treated with Placebo Capsule. Results: Khanda Kushmanda Avaleha cured 12 patients i.e. 85.71% followed by markedly improvement in 2 patients i.e. 14.28%. Placebo capsule mildly improved 61.54% i.e. 8 patients followed by no improvement to 38.46% i.e. 5 patients. Discussion: The effect of therapy on chief complaints in Group A is better than Group B. Percentage wise Khanda Kusmanda Avaleha gave 86.3% relief on duration of blood loss, 85.7% on Interval between two cycles and 58.3% on Amount of total blood loss during one period while Placebo capsule gave 27.2% relief on Duration of blood loss, 20% on Interval between cycle, and 21.05% relief on Amount of blood loss. So, more relief was observed on chief complaints in Group - A i.e. Khanda Kusmanda Avaleha