4 research outputs found
Simultaneous accessory pathway and AV node mechanical block
We report a clinical case of a 22-year-old female referred to our institution due to palpitations
and preexcitation. Her ECG suggested a right superior paraseptal accessory pathway (AP),
which was localised during the electrophysiological study at the superior paraseptal region in
close proximity to the His recordings. Reproducible orthodromic reciprocating tachycardia
was induced by atrial pacing with extrastimuli. Cryo-mapping performed in the area of earliest
atrial activation was not able to terminate the tachycardia. A second attempt, slightly more
posterior, caused mechanical block of the AP, which rendered the tachycardia non-inducible.
More pressure with the ablation catheter determined a Wenckebach type supra-hisian AV
block, which was transient but reproducible. Given this finding no ablation was done.
Simultaneous block to the AP and the atrioventricular node has rarely been reported using
radiofrequency energy. However, to our knowledge this phenomenon has not been previously
reported in large series using cryo-thermal energ
Polyunsaturated fatty acids in atrial fibrillation: Looking for the proper candidates
This Document is Protected by copyright and was first published by Frontiers. All rights reserved. it is reproduced with permissionAtrial fibrillation (AF) is the most common sustained arrhythmia encountered in clinical practice
with growing prevalence in developed countries. Several medical and interventional
therapies, such as atrial specific drugs and pulmonary vein isolation, have demonstrated
prevention of recurrences. However, their suboptimal long-term success and significant
rate of secondary effects have led to intensive research in the last decade focused on
novel alternative and supplemental therapies. One such candidate is polyunsaturated fatty
acids (PUFAs). Because of their biological properties, safety, simplicity, and relatively cheap
cost, there is a special clinical interest in omega-3 PUFAs as a possible antiarrhythmic agent.
Obtained from diets rich in fish, they represent one of the current supplemental therapies.
At the cellular level, an increasing body of evidence has shown that n-3 PUFAs exert a
variety of effects on cardiac ion channels, membrane dynamic properties, inflammatory
cascade, and other targets related to AF prevention. In this article, we review the current
basic and clinical evidence pertinent to n-3 PUFAs in AF treatment and prevention.We also
discuss controversial outcomes among clinical studies and propose specific subsets of AF
patients who will benefit most from n-3 PUFAsNHLBI Grant K99-HL105574 to SFN and the Alfonso Martín Escudero Foundation Grant to DF
Cardiac tamponade during catheter-based ablation of cardiac arrhythmias: experience matters
The CNIC is supported by the Ministry of Economy, Industry and Competitiveness (MINECO) and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (MINECO award SEV-2015-0505). ISCIIIFEDER (European Funding for Regional Development), CB16/11/00486 (CJ Calvo, J Millet), CB16/11/00458 (D Filgueiras-Rama)