Alginate electrodeposition onto three-dimensional porous Co-Ni films as drug delivery platforms

Three-dimensional porous Co–Ni films/alginate hybrid materials have been successfully prepared by electrodeposition to be used as a steerable magnetic device for drug delivery. Firstly, 3D porous Co–Ni films were prepared as substrates for the subsequent electrodeposition of the alginate biopolymer. Cyclic voltammetry, galvanostatic and potentiostatic studies were performed to establish the best conditions to obtain porous Co–Ni films. The electrochemical experiments were carried out in an electrolyte containing the metal salts and ammonium chloride at low pHs. In a second stage, the electrochemical deposition of alginate as a biocompatible polymer drug delivery carrier was performed. The characteristics of the alginate matrix were investigated in terms of electrochemical properties, morphology and drug release. The hybrid material obtained showed soft-magnetic behavior and drug release indicating its suitability to be used as a steerable magnetic drug delivery device.Postprint (author's final draft

Análisis de la cobertura mediática del caso de contagio por ébola de Teresa Romero en España, a través de las portadas de ABC y El País

Treball Final de Grau en Periodisme. Codi: PE0932. Curs acadèmic 2014-2015Este trabajo analiza el tratamiento informativo que se hizo del caso de contagio de Teresa Romero por ébola en España, a través del seguimiento de las portadas de dos de los principales medios generalistas españoles (ABC y El País) desde el 7 de agosto al 2 de noviembre de 2014. El objetivo es detectar la diferencia de tratamiento informativo en la comunicación de una crisis sanitaria y para comprobar dónde están los límites de la ética y la deontología profesional. Este trabajo pretende obtener como resultado ejemplos de la degradación de la ética informativa en este país en una profunda crisis de valores. Se demuestra que hay una manipulación a través de las portadas del ABC.This work analizes the informative treatment that has become the landmark case of transmission of ebola to Teresa Romero in Spain, through the front cover of two of the main Spanish mainstream media (ABC and El País) since August the 7th, 2014 until November the 2nd, 2014. The objective is point out the difference in informative treatment in the communication of a sanitarian crisis and check where the boundaries of ethics and professional conduct are. This research aims to obtain examples of the degradation of information ethics in this country into a deep crisis of values. At the end it shows there is a manipulation through the ABC's front covers

Test Case Generation for Object-Oriented Imperative Languages in CLP

Testing is a vital part of the software development process. Test Case Generation (TCG) is the process of automatically generating a collection of test cases which are applied to a system under test. White-box TCG is usually performed by means of symbolic execution, i.e., instead of executing the program on normal values (e.g., numbers), the program is executed on symbolic values representing arbitrary values. When dealing with an object-oriented (OO) imperative language, symbolic execution becomes challenging as, among other things, it must be able to backtrack, complex heap-allocated data structures should be created during the TCG process and features like inheritance, virtual invocations and exceptions have to be taken into account. Due to its inherent symbolic execution mechanism, we pursue in this paper that Constraint Logic Programming (CLP) has a promising unexploited application field in TCG. We will support our claim by developing a fully CLP-based framework to TCG of an OO imperative language, and by assessing it on a corresponding implementation on a set of challenging Java programs. A unique characteristic of our approach is that it handles all language features using only CLP and without the need of developing specific constraint operators (e.g., to model the heap)

Platinum Electrodeposition in an Ionic Liquid Analogue. Solvent Stability Monitoring

The use of ionic liquid analogues as solvents has increased in order to substitute the aqueous solvents in some applications in which the side reactions are undesirable. However these solvents prepared from the mixture in the eutectic proportion of species establishing hydrogen bonds are susceptible of electrochemical reactions. The study of platinum deposition on vitreous carbon in an ionic liquid analogue (2 urea: choli ne chloride) is presented; the electrochemical study has permitted to interpret the sequence of the metal deposition process and simultaneously to analyze the behavior of the ionic liquid analogue along the process. Reduction reactions of the solvent relat ed both to the electronation of choline and hydrogen formation have been detected. Different substrata have been used in order to test the possibility and the extent of these reactions depending on the nature of material. The results indicate that the feas ible electrochemical window of the substrate/solvent is highly dependent of the kind of substrate; the negative limit is tied by the massive hydrogen reaction, reaction enhanced by the electrocatalytic character of the substrate

Analysis and Simulation of the Leg of an Hexapod Robot for Remote Exploration

The locomotion system is determined by the terrain conditions. The aim of this paper is to introduce the characteristics and simulation of a hexapod legged robot that can be easily used for exploration of abrupt and harsh terrains, Jike the Rio Tinto environment. A walking robot seems like the best option for this kind of terrain. Some of the advantages are that they do not need continuous terrain, they have less problems with sliding and they also have greater capacity to overcome obstacles as they produce Jess harm to the environment that the scientist wants to explore on the contrary when faced with mechanical design they present a design challenge, also in the static and dynamic analysis problem of a legged robot, there is a high complexity that has to be taken into account. This paper shows how to easily cope with the analysis of hexapod robot movement based on a design developed by the Center of Astrobiology INTA-CSIC for operation in RioTinto (Huelva - Spain)