Modeling dust emission in PN IC 418

We investigated the infrared (IR) dust emission from PN IC 418, using a detailed model controlled by a previous determination of the stellar properties and the characteristics of the photoionized nebula, keeping as free parameters the dust types, amounts and distributions relative to the distance of the central star. The model includes the ionized region and the neutral region beyond the recombination front (Photodissociation region, or PDR), where the [OI] and [CII] IR lines are formed. We succeeded in reproducing the observed infrared emission from 2 to 200~\mm. The global energy budget is fitted by summing up contributions from big grains of amorphous carbon located in the neutral region and small graphite grains located in the ionized region (closer to the central star). Two emission features seen at 11.5 and 30~\mm are also reproduced by assuming them to be due to silicon carbide (SiC) and magnesium and iron sulfides (Mg$_x$Fe$_{1-x}$S), respectively. For this, we needed to consider ellipsoidal shapes for the grains to reproduce the wavelength distribution of the features. Some elements are depleted in the gaseous phase: Mg, Si, and S have sub-solar abundances (-0.5 dex below solar by mass), while the abundance of C+N+O+Ne by mass is close to solar. Adding the abundances of the elements present in the dusty and gaseous forms leads to values closer to but not higher than solar, confirming that the identification of the feature carriers is plausible. Iron is strongly depleted (3 dex below solar) and the small amount present in dust in our model is far from being enough to recover the solar value. A remaining feature is found as a residue of the fitting process, between 12 and 25~\mm, for which we do not have identification.Comment: Accepted for publication in Astronomy & Astrophysics. V2: adding reference

Density biases and temperature relations for DESIRED HII regions

We present a first study based on the analysis of the DEep Spectra of Ionized REgions Database (DESIRED). This is a compilation of 190 high signal-to-noise ratio optical spectra of HII regions and other photoionized nebulae, mostly observed with 8-10m telescopes and containing $\sim$29380 emission lines. We find that the electron density --$n_{\rm e}$-- of the objects is underestimated when [SII] $\lambda6731/\lambda6716$ and/or [OII] $\lambda3726/\lambda3729$ are the only density indicators available. This is produced by the non-linear density dependence of the indicators in the presence of density inhomogeneities. The average underestimate is $\sim 300$ cm$^{-3}$ in extragalactic HII regions, introducing systematic overestimates of $T_{\rm e}$([OII]) and $T_{\rm e}$([SII]) compared to $T_{\rm e}$([NII]). The high-sensitivity of [OII] $\lambda\lambda7319+20+30+31/\lambda\lambda3726+29$ and [SII] $\lambda\lambda4069+76/\lambda\lambda6716+31$ to density makes them more suitable for the diagnosis of the presence of high-density clumps. If $T_{\rm e}$([NII]) is adopted, the density underestimate has a small impact in the ionic abundances derived from optical spectra, being limited to up to $\sim$0.1 dex when auroral [SII] and/or [OII] lines are used. However, these density effects are critical for the analysis of infrared fine structure lines, such as those observed by the JWST in local star forming regions, implying strong underestimates of the ionic abundances. We present temperature relations between $T_{\rm e}$([OIII]), $T_{\rm e}$([ArIII]), $T_{\rm e}$([SIII]) and $T_{\rm e}$([NII]) for the extragalactic HII regions. We confirm a non-linear dependence between $T_{\rm e}$([OIII])-$T_{\rm e}$([NII]) due to a more rapid increase of $T_{\rm e}$([OIII]) at lower metallicities.Comment: Accepted for publication in MNRA

Signals: I. Survey description

SIGNALS, the Star formation, Ionized Gas, and Nebular Abundances Legacy Survey, is a large observing programme designed to investigate massive star formation and H II regions in a sample of local extended galaxies. The programme will use the imaging Fourier transform spectrograph SITELLE at the Canada–France–Hawaii Telescope. Over 355 h (54.7 nights) have been allocated beginning in fall 2018 for eight consecutive semesters. Once completed, SIGNALS will provide a statistically reliable laboratory to investigate massive star formation, including over 50 000 resolved H II regions: the largest, most complete, and homogeneous data base of spectroscopically and spatially resolved extragalactic H II regions ever assembled. For each field observed, three datacubes covering the spectral bands of the filters SN1 (363–386 nm), SN2 (482–513 nm), and SN3 (647–685 nm) are gathered. The spectral resolution selected for each spectral band is 1000, 1000, and 5000, respectively. As defined, the project sample will facilitate the study of small-scale nebular physics and many other phenomena linked to star formation at a mean spatial resolution of ∼20 pc. This survey also has considerable legacy value for additional topics, including planetary nebulae, diffuse ionized gas, and supernova remnants. The purpose of this paper is to present a general outlook of the survey, notably the observing strategy, galaxy sample, and science requirements

First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR)

Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therapeutic guidelines are developed. The objective of the study is to develop clinical practice guidelines for Latin American patients with lupus. Two independent teams (rheumatologists with experience in lupus management and methodologists) had an initial meeting in Panama City, Panama, in April 2016. They selected a list of questions for the clinical problems most commonly seen in Latin American patients with SLE. These were addressed with the best available evidence and summarised in a standardised format following the Grading of Recommendations Assessment, Development and Evaluation approach. All preliminary findings were discussed in a second face-to-face meeting in Washington, DC, in November 2016. As a result, nine organ/system sections are presented with the main findings; an 'overarching' treatment approach was added. Special emphasis was made on regional implementation issues. Best pharmacologic options were examined for musculoskeletal, mucocutaneous, kidney, cardiac, pulmonary, neuropsychiatric, haematological manifestations and the antiphospholipid syndrome. The roles of main therapeutic options (ie, glucocorticoids, antimalarials, immunosuppressant agents, therapeutic plasma exchange, belimumab, rituximab, abatacept, low-dose aspirin and anticoagulants) were summarised in each section. In all cases, benefits and harms, certainty of the evidence, values and preferences, feasibility, acceptability and equity issues were considered to produce a recommendation with special focus on ethnic and socioeconomic aspects. Guidelines for Latin American patients with lupus have been developed and could be used in similar settings.Fil: Pons Estel, Bernardo A.. Centro Regional de Enfermedades Autoinmunes y Reumáticas; ArgentinaFil: Bonfa, Eloisa. Universidade de Sao Paulo; BrasilFil: Soriano, Enrique R.. Instituto Universitario Hospital Italiano de Buenos Aires. Rectorado.; ArgentinaFil: Cardiel, Mario H.. Centro de Investigación Clínica de Morelia; MéxicoFil: Izcovich, Ariel. Hospital Alemán; ArgentinaFil: Popoff, Federico. Hospital Aleman; ArgentinaFil: Criniti, Juan M.. Hospital Alemán; ArgentinaFil: Vásquez, Gloria. Universidad de Antioquia; ColombiaFil: Massardo, Loreto. Universidad San Sebastián; ChileFil: Duarte, Margarita. Hospital de Clínicas; ParaguayFil: Barile Fabris, Leonor A.. Hospital Angeles del Pedregal; MéxicoFil: García, Mercedes A.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Amigo, Mary Carmen. Centro Médico Abc; MéxicoFil: Espada, Graciela. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; ArgentinaFil: Catoggio, Luis J.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: Sato, Emilia Inoue. Universidade Federal de Sao Paulo; BrasilFil: Levy, Roger A.. Universidade do Estado de Rio do Janeiro; BrasilFil: Acevedo Vásquez, Eduardo M.. Universidad Nacional Mayor de San Marcos; PerúFil: Chacón Díaz, Rosa. Policlínica Méndez Gimón; VenezuelaFil: Galarza Maldonado, Claudio M.. Corporación Médica Monte Sinaí; EcuadorFil: Iglesias Gamarra, Antonio J.. Universidad Nacional de Colombia; ColombiaFil: Molina, José Fernando. Centro Integral de Reumatología; ColombiaFil: Neira, Oscar. Universidad de Chile; ChileFil: Silva, Clóvis A.. Universidade de Sao Paulo; BrasilFil: Vargas Peña, Andrea. Hospital Pasteur Montevideo; UruguayFil: Gómez Puerta, José A.. Hospital Clinic Barcelona; EspañaFil: Scolnik, Marina. Instituto Universitario Hospital Italiano de Buenos Aires. Rectorado.; ArgentinaFil: Pons Estel, Guillermo J.. Centro Regional de Enfermedades Autoinmunes y Reumáticas; Argentina. Hospital Provincial de Rosario; ArgentinaFil: Ugolini Lopes, Michelle R.. Universidade de Sao Paulo; BrasilFil: Savio, Verónica. Instituto Universitario Hospital Italiano de Buenos Aires. Rectorado.; ArgentinaFil: Drenkard, Cristina. University of Emory; Estados UnidosFil: Alvarellos, Alejandro J.. Hospital Privado Universitario de Córdoba; ArgentinaFil: Ugarte Gil, Manuel F.. Universidad Cientifica del Sur; Perú. Hospital Nacional Guillermo Almenara Irigoyen; PerúFil: Babini, Alejandra. Instituto Universitario Hospital Italiano de Buenos Aires. Rectorado.; ArgentinaFil: Cavalcanti, André. Universidade Federal de Pernambuco; BrasilFil: Cardoso Linhares, Fernanda Athayde. Hospital Pasteur Montevideo; UruguayFil: Haye Salinas, Maria Jezabel. Hospital Privado Universitario de Córdoba; ArgentinaFil: Fuentes Silva, Yurilis J.. Universidad de Oriente - Núcleo Bolívar; VenezuelaFil: Montandon De Oliveira E Silva, Ana Carolina. Universidade Federal de Goiás; BrasilFil: Eraso Garnica, Ruth M.. Universidad de Antioquia; ColombiaFil: Herrera Uribe, Sebastián. Hospital General de Medellin Luz Castro de Gutiérrez; ColombiaFil: Gómez Martín, DIana. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Robaina Sevrini, Ricardo. Universidad de la República; UruguayFil: Quintana, Rosana M.. Hospital Provincial de Rosario; Argentina. Centro Regional de Enfermedades Autoinmunes y Reumáticas; ArgentinaFil: Gordon, Sergio. Hospital Interzonal General de Agudos Dr Oscar Alende. Unidad de Reumatología y Enfermedades Autoinmunes Sistémicas; ArgentinaFil: Fragoso Loyo, Hilda. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Rosario, Violeta. Hospital Docente Padre Billini; República DominicanaFil: Saurit, Verónica. Hospital Privado Universitario de Córdoba; ArgentinaFil: Appenzeller, Simone. Universidade Estadual de Campinas; BrasilFil: Dos Reis Neto, Edgard Torres. Universidade Federal de Sao Paulo; BrasilFil: Cieza, Jorge. Hospital Nacional Edgardo Rebagliati Martins; PerúFil: González Naranjo, Luis A.. Universidad de Antioquia; ColombiaFil: González Bello, Yelitza C.. Ceibac; MéxicoFil: Collado, María Victoria. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Sarano, Judith. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Retamozo, Maria Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Sattler, María E.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Gamboa Cárdenas, Rocio V.. Hospital Nacional Guillermo Almenara Irigoyen; PerúFil: Cairoli, Ernesto. Universidad de la República; UruguayFil: Conti, Silvana M.. Hospital Provincial de Rosario; ArgentinaFil: Amezcua Guerra, Luis M.. Instituto Nacional de Cardiologia Ignacio Chavez; MéxicoFil: Silveira, Luis H.. Instituto Nacional de Cardiologia Ignacio Chavez; MéxicoFil: Borba, Eduardo F.. Universidade de Sao Paulo; BrasilFil: Pera, Mariana A.. Hospital Interzonal General de Agudos General San Martín; ArgentinaFil: Alba Moreyra, Paula B.. Universidad Nacional de Córdoba. Facultad de Medicina; ArgentinaFil: Arturi, Valeria. Hospital Interzonal General de Agudos General San Martín; ArgentinaFil: Berbotto, Guillermo A.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Gerling, Cristian. Hospital Interzonal General de Agudos Dr Oscar Alende. Unidad de Reumatología y Enfermedades Autoinmunes Sistémicas; ArgentinaFil: Gobbi, Carla Andrea. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gervasoni, Viviana L.. Hospital Provincial de Rosario; ArgentinaFil: Scherbarth, Hugo R.. Hospital Interzonal General de Agudos Dr Oscar Alende. Unidad de Reumatología y Enfermedades Autoinmunes Sistémicas; ArgentinaFil: Brenol, João C. Tavares. Hospital de Clinicas de Porto Alegre; BrasilFil: Cavalcanti, Fernando. Universidade Federal de Pernambuco; BrasilFil: Costallat, Lilian T. Lavras. Universidade Estadual de Campinas; BrasilFil: Da Silva, Nilzio A.. Universidade Federal de Goiás; BrasilFil: Monticielo, Odirlei A.. Hospital de Clinicas de Porto Alegre; BrasilFil: Seguro, Luciana Parente Costa. Universidade de Sao Paulo; BrasilFil: Xavier, Ricardo M.. Hospital de Clinicas de Porto Alegre; BrasilFil: Llanos, Carolina. Universidad Católica de Chile; ChileFil: Montúfar Guardado, Rubén A.. Instituto Salvadoreño de la Seguridad Social; El SalvadorFil: Garcia De La Torre, Ignacio. Hospital General de Occidente; MéxicoFil: Pineda, Carlos. Instituto Nacional de Rehabilitación; MéxicoFil: Portela Hernández, Margarita. Umae Hospital de Especialidades Centro Medico Nacional Siglo Xxi; MéxicoFil: Danza, Alvaro. Hospital Pasteur Montevideo; UruguayFil: Guibert Toledano, Marlene. Medical-surgical Research Center; CubaFil: Reyes, Gil Llerena. Medical-surgical Research Center; CubaFil: Acosta Colman, Maria Isabel. Hospital de Clínicas; ParaguayFil: Aquino, Alicia M.. Hospital de Clínicas; ParaguayFil: Mora Trujillo, Claudia S.. Hospital Nacional Edgardo Rebagliati Martins; PerúFil: Muñoz Louis, Roberto. Hospital Docente Padre Billini; República DominicanaFil: García Valladares, Ignacio. Centro de Estudios de Investigación Básica y Clínica; MéxicoFil: Orozco, María Celeste. Instituto de Rehabilitación Psicofísica; ArgentinaFil: Burgos, Paula I.. Pontificia Universidad Católica de Chile; ChileFil: Betancur, Graciela V.. Instituto de Rehabilitación Psicofísica; ArgentinaFil: Alarcón, Graciela S.. Universidad Peruana Cayetano Heredia; Perú. University of Alabama at Birmingahm; Estados Unido

Baseline characteristics of patients in the reduction of events with darbepoetin alfa in heart failure trial (RED-HF)

<p>Aims: This report describes the baseline characteristics of patients in the Reduction of Events with Darbepoetin alfa in Heart Failure trial (RED-HF) which is testing the hypothesis that anaemia correction with darbepoetin alfa will reduce the composite endpoint of death from any cause or hospital admission for worsening heart failure, and improve other outcomes.</p> <p>Methods and results: Key demographic, clinical, and laboratory findings, along with baseline treatment, are reported and compared with those of patients in other recent clinical trials in heart failure. Compared with other recent trials, RED-HF enrolled more elderly [mean age 70 (SD 11.4) years], female (41%), and black (9%) patients. RED-HF patients more often had diabetes (46%) and renal impairment (72% had an estimated glomerular filtration rate <60 mL/min/1.73 m2). Patients in RED-HF had heart failure of longer duration [5.3 (5.4) years], worse NYHA class (35% II, 63% III, and 2% IV), and more signs of congestion. Mean EF was 30% (6.8%). RED-HF patients were well treated at randomization, and pharmacological therapy at baseline was broadly similar to that of other recent trials, taking account of study-specific inclusion/exclusion criteria. Median (interquartile range) haemoglobin at baseline was 112 (106–117) g/L.</p> <p>Conclusion: The anaemic patients enrolled in RED-HF were older, moderately to markedly symptomatic, and had extensive co-morbidity.</p&gt

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Author Correction: The messy death of a multiple star system and the resulting planetary nebula as observed by JWST

Stars and planetary system

Nutrición parenteral domiciliaria en España 2018. Informe del Grupo de Nutrición Artificial Domiciliaria y Ambulatoria NADYA

Objetivo: comunicar los datos de nutrición parenteral domiciliaria (NPD) obtenidos del registro del grupo NADYA-SENPE (www.nadya-senpe.com) del año 2018. Material y métodos: análisis descriptivo de los datos recogidos de pacientes adultos y pediátricos con NPD en el registro NADYA-SENPE del 1 de enero al 31 de diciembre de 2018. Resultados: se registraron 278 pacientes (54, 7% mujeres), 23 niños y 255 adultos, procedentes de 45 hospitales españoles, lo que representa una tasa de prevalencia de 5, 95 pacientes/millón de habitantes/año 2018. El diagnóstico más frecuente en adultos fue “oncológico paliativo” (22, 0%), seguido de “otros”. En niños fue la enfermedad de Hirschsprung junto con la enterocolitis necrotizante, con cuatro casos (17, 4%). El primer motivo de indicación fue síndrome de intestino corto tanto en niños (60, 9%) como en adultos (35, 7%). El tipo de catéter más utilizado fue el tunelizado tanto en niños (81, 0%) como en adultos (41, 1%). Finalizaron 75 episodios, la causa más frecuente fue el fallecimiento (52, 0%) y el paso a vía oral (33, 3%). Conclusiones: el número de centros y profesionales colaboradores en el registro de pacientes que reciben NPD se mantiene estable, así como las principales indicaciones y los motivos de finalización de la NPD. Aim: To communicate home parenteral nutrition (HPN) data obtained from the HPN registry of the NADYA-SENPE group (www.nadya-senpe.  com) for the year 2018. Material and methods: Descriptive analysis of the data collected from adult and pediatric patients with HPN in the NADYA-SENPE group registry from January 1st, 2018 to December 31st, 2018.  Results: There were 278 patients from 45 Spanish hospitals (54.7% women), 23 children and 255 adults, which represent a prevalence rate of 5.95 patients/million inhabitants/year 2018. The most frequent diagnosis in adults was “palliative cancer” (22.0%), followed by “others”. In children it was Hirschsprung’s disease together with necrotizing enterocolitis, with four cases (17.4%). The first indication was short bowel syndrome in both children (60.9%) and adults (35.7%). The most frequently used type of catheter was tunneled in both children (81.0%) and adults (41.1%). Ending 75 episodes, the most frequent cause was death (52.0%) and change to oral feeding (33.3%). Conclusions: The number of centers and collaborating professionals in the registry of patients receiving HPN remains stable, as well as the main indications and reasons for termination of HPN

Catching a grown-up starfish planetary nebula – II. Plasma analysis and central star properties of PC 22

After performing the morpho-kinematic analysis of the planetary nebula (PN) PC 22, we now present its nebular and stellar analysis. The plasma investigation relies on the novel use of a Monte Carlo analysis associated with the PYNEB code for the uncertainty propagation. The innermost region of the nebula shows electronic temperatures Te ≈ 10 800 K using [N II] and ≈13 000 K using [O III] and electronic densities ne ≈ 600 cm−3. We also used for the first time a machine learning algorithm to calculate ionization correction factors (ICFs) specifically adapted to PC 22. This has allowed us to have pioneer ICFs for (S+ + S++)/O++, Cl++/O++, and Ar3+ + Ar4+, as well as a possible new determination for the total abundance of neon. The study of the stellar spectrum revealed the presence of broad emission lines consistent with a Wolf–Rayet-type [WR] classification and more precisely a [WO1] subtype based on different qualitative and quantitative criteria. This classification is also coherent with the high stellar temperature derived from the reproduction of the ionization state of the gas with the Mexican Million Models data base (3MdB) and the best-fitting model obtained with the NLTE model atmosphere code PoWR. PC 22 is therefore a new addition to the [WO1]-subtype PNe. © 2021 The Author(s) Published by Oxford University Press on behalf of Royal Astronomical Society.LS acknowledges support from PAPIIT grant IN101819 (Mexico). VGL and CM acknowledge grants CONACYT/CB2015 – 254132 and UNAM/PAPIIT – IN101220. VMAGG acknowledges support from the Programa de Becas posdoctorales funded by Dirección General de Asuntos del Personal Académico of the Universidad Nacional Autónoma de México (DGAPA, UNAM). MAG acknowledges support of the grant PGC2018-102184-B-I00 of the Spanish Ministerio de Ciencias, Innovación y Universidades. Also, we want to thank the OAN-SPM staff and the CATT for time allocation. This study is based on observations made with the 2.1 m telescope of the Observatorio Astronómico Nacional at the Sierra de San Pedro Mártir (OAN-SPM), which is a national facility operated by the Instituto de Astronomía of the Universidad Nacional Autónoma de México. This research has made use of the NASA/IPAC Infrared Science Archive, which is operated by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration. We have also used archival observations made with the NASA/ESA Hubble Space Telescope, and obtained from the Hubble Legacy Archive, which is a collaboration between the Space Telescope Science Institute (STScI/NASA), the Space Telescope European Coordinating Facility (ST-ECF/ESA), and the Canadian Astronomy Data Centre (CADC/NRC/CSA). This paper has been edited using the Overleaf facility.With funding from the Spanish government through the Severo Ochoa Centre of Excellence accreditation SEV-2017-0709.Peer reviewe

Detailed studies of IPHAS sources - I. The disrupted late bipolar IPHASX J193718.6+202102

We present a detailed analysis of the new planetary nebula (PN) IPHASX J193718.6+202102 using deep imaging and intermediate- and high-resolution spectroscopy that are interpreted through morpho-kinematic and photoionization modelling. The physical structure of the nebula consists of a fragmented torus and an extremely faint orthogonal bipolar outflow, contrary to the pinched waist PN morphology suggested by its optical image. Our kinematic analysis indicates that the torus is expanding at 25 ± 5 km s-1 and is gradually breaking up. At an estimated distance of 7.1-0.3+0.8 kpc, the corresponding kinematic age of ∼26 000 yr is consistent with a faint and disintegrating PN. The intermediate-resolution spectra reveal an excited PN with chemical abundances typical of Type II PNe. Based on the latter, we also estimate an initial mass for the progenitor in the range 2-3 M⊙ and a central star (CSPN) mass MCSPN ∼0.61 M⊙. The Spitzer MIPS 24 μm emission that closely follows the fragmented torus could be attributed to the emission of [O iv] at 25.9 μm rather than to dust emission. All the results coherently point towards an evolved moderately massive bipolar Type II PN on the brink of dissolving into the interstellar medium. © 2020 The Author(s).The authors are thankful to the referees for their comments that improved this paper. LS acknowledges support from UNAM DGAPA PAPIIT project IN101819 (Mexico). MAG acknowledges support from grant AYA PGC2018-102184-B-I00 co-funded with FEDER funds. SZ works under the collaboration agreement ‘UNAM-TecNM 43310-3020-30-IX-15’. JAT and MAG are funded by UNAM DGAPA PAPIIT project IA100720. GRL acknowledges support from CONACYT (grant 263373) and PRODEP (Mexico). This work is partially based on observations collected at the Observatorio Astronómico Nacional at San Pedro Mártir, B.C., Mexico and we thank the daytime and night support staff at the OAN-SPM for facilitating and helping obtain our observations. Based on observations made with the Nordic Optical Telescope, operated by the Nordic Optical Telescope Scientific Association, and the Gran Telescopio Canarias (GTC), both installed in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofísica de Canarias in La Palma, Spain. This paper makes use of data obtained as part of the INT Photometric H α Survey of the Northern Galactic Plane (IPHAS, www.iphas.org) carried out at the Isaac Newton Telescope (INT). The INT is operated on the island of La Palma by the Isaac Newton Group in the Spanish Observatorio del Roque de los Muchachos of the Instituto de Astrofisica de Canarias. All IPHAS data are processed by the Cambridge Astronomical Survey Unit, at the Institute of Astronomy in Cambridge. The bandmerged DR2 catalogue was assembled at the Centre for Astrophysics Research, University of Hertfordshire, supported by STFC grant ST/J001333/1. The OSN director is acknowledged for awarding observations through a DDT programme and the telescope operator Alfredo Sota for conducting the observations. This work is based in part on observations made with the Spitzer Space Telescope, which is operated by the Jet Propulsion Laboratory, California Institute of Technology under a contract with NASA. In memoriam of Johannes Andersen, director of the NOT from 2002 to 2013.Peer reviewe