MAPPING LOCAL CLIMATE ZONES WITH A VECTOR-BASED GIS METHOD

In this study we determined Local Climate Zones in a South-Hungarian city, using vector-based and raster-based databases. We calculated seven of the originally proposed ten physical (geometric, surface cover and radiative) properties for areas which are based on the mobile temperature measurement campaigns earlier carried out in this city.As input data we applied 3D building database (earlier created with photogrammetric methods), 2D road database, topographic map, aerial photographs, remotely sensed reflectance information from RapidEye satellite image and our local knowledge about the area. The values of the properties were calculated by GIS methods developed for this purpose.We derived for the examined areas and applied for classification sky view factor, mean building height, terrain roughness class, building surface fraction, pervious surface fraction, impervious surface fraction and albedo.Six built and one land cover LCZ classes could be detected with this method on our study area. From each class one circle area was selected, which is representative for that class. Their thermal reactions were examined with the application of mobile temperature measurement dataset. The comparison was made in cases, when the weather was clear and calm and the surface was dry. We found that compact built-in types have more temperature surplus than open ones, and midrise types also have more than lowrise ones. According to our primary results, these categories provide a useful opportunity for intra- and inter-urban comparisons

Distribution of transposons in Botrytis cinerea isolates collected from the wine regions of Eger and Tokaj, Hungary

Botryotinia fuckeliana (de Bary ex de Bary) Whetzel (anamorph: Botrytis cinerea Pers.:Fr.) is a cosmopolitan ascomycetous fungus that causes grey mould on a great number of plants in the temperate zone worldwide by infecting various tissues (Jarvis, 1980). In grapevine, the frequent occurrence of B. cinerea prior harvesting results in serious losses of fruits and deterioration of wine quality. This is also the case in Eger, a major Hungarian wine region in the North-Eastern part of the country, where B. cinerea is considered to the third most important grapevine pathogen after downy mildew (Plasmopara viticola /Berk. and Curt ex de Bary/ Berl. and de Toni) and powdery mildew [Erysiphe necator Schwein. var. necator (syn.: Uncinula necator /Schwein./ Burrill var. necator)], with an estimated annual loss of up to 15-20 %. In contrast, some 100 km eastwards in the Tokaj wine region, B. cinerea is also responsible for the phenomenon called ‘pourriture noble’ (noble rot). Under certain unique environmental conditions, mycelia growing on the surface of the uninjured, healthy berry drains water (but no substrates) via the fine infection hyphae. As a consequence, the concentration of all the soluble compounds within the berry significantly increase (Jarvis, 1980). Such berries yield the sweet, special quality wine called „aszu”

Mucosal Immunity and the Intestinal Microbiome in the Development of Critical Illness

The intestinal community, including the commensal microbial flora as well as the host tissues, represents a functional whole in vivo. Under physiological circumstances, this symbiosis brings great benefit for the host; however, critical illness induces profound disturbances in the intestinal ecosystem affecting both procaryotic and eucaryotic members. Today, 25 years after the gut was first described as a motor of multiple organ dysfunction syndrome, the role of the injured splanchnic compartment in the pathomechanism and development of critical illness is still in the first line of research. Multiple mechanisms have been identified by which the stressed gut may affect host homeostasis, and how external intervention might help to rebalance physiology. This paper provides a brief overview of the present of this field.</jats:p

Medieval and Ottoman period (14th–17th c.) Archaeology in the Drava River region, Hungary

The paper is a short summary of the main archaeological outcomes of an interdisciplinary project in a section of the Drava river crossing the territory of Somogy county, in Hungary. One of the study areas is the vicinity of Berzence where medieval settlement patterns, land use and economy have been reconstructed on the basis of historical sources and an archaeological field survey. A comprehensive review of architectural history and material culture of the Ottoman Period stronghold in Barcs was the other area under investigation. Research there was based on written sources and the archaeological assemblage recovered from the palisaded fort. Zooarchaeological research at this site revealed some significant culture historical aspects of this stronghold. Underwater archaeological investigations carried out in the Drava river itself and aerial exploration of the study areas also supplied valuable archaeological results

On the Communication Complexity of Secure Computation

Information theoretically secure multi-party computation (MPC) is a central primitive of modern cryptography. However, relatively little is known about the communication complexity of this primitive. In this work, we develop powerful information theoretic tools to prove lower bounds on the communication complexity of MPC. We restrict ourselves to a 3-party setting in order to bring out the power of these tools without introducing too many complications. Our techniques include the use of a data processing inequality for residual information - i.e., the gap between mutual information and G\'acs-K\"orner common information, a new information inequality for 3-party protocols, and the idea of distribution switching by which lower bounds computed under certain worst-case scenarios can be shown to apply for the general case. Using these techniques we obtain tight bounds on communication complexity by MPC protocols for various interesting functions. In particular, we show concrete functions that have "communication-ideal" protocols, which achieve the minimum communication simultaneously on all links in the network. Also, we obtain the first explicit example of a function that incurs a higher communication cost than the input length in the secure computation model of Feige, Kilian and Naor (1994), who had shown that such functions exist. We also show that our communication bounds imply tight lower bounds on the amount of randomness required by MPC protocols for many interesting functions.Comment: 37 page

Exclusive neuronal expression of SUCLA2 in the human brain

SUCLA2 encodes the ATP-forming subunit (A-SUCL-) of succinyl-CoA ligase, an enzyme of the citric acid cycle. Mutations in SUCLA2 lead to a mitochondrial disorder manifesting as encephalomyopathy with dystonia, deafness and lesions in the basal ganglia. Despite the distinct brain pathology associated with SUCLA2 mutations, the precise localization of SUCLA2 protein has never been investigated. Here we show that immunoreactivity of A-SUCL- in surgical human cortical tissue samples was present exclusively in neurons, identified by their morphology and visualized by double labeling with a fluorescent Nissl dye. A-SUCL- immunoreactivity co-localized >99% with that of the d subunit of the mitochondrial F0-F1 ATP synthase. Specificity of the anti-A-SUCL- antiserum was verified by the absence of labeling in fibroblasts from a patient with a complete deletion of SUCLA2. A-SUCL- immunoreactivity was absent in glial cells, identified by antibodies directed against the glial markers GFAP and S100. Furthermore, in situ hybridization histochemistry demonstrated that SUCLA2 mRNA was present in Nissl-labeled neurons but not glial cells labeled with S100. Immunoreactivity of the GTP-forming subunit (G-SUCL-) encoded by SUCLG2, or in situ hybridization histochemistry for SUCLG2 mRNA could not be demonstrated in either neurons or astrocytes. Western blotting of post mortem brain samples revealed minor G-SUCL- immunoreactivity that was however, not upregulated in samples obtained from diabetic versus non-diabetic patients, as has been described for murine brain. Our work establishes that SUCLA2 is expressed exclusively in neurons in the human cerebral cortex

Prevention of Bone Bridge Formation Using Transplantation of the Autogenous Mesenchymal Stem Cells to Physeal Defects: An Experimental Study in Rabbits

Physeal cartilage is known to have poor self-repair capacity after injury. Evaluation of the ability of cultured mesenchymal stem cells to repair damaged physis is the topic of current research. In 10 immature New Zealand white rabbits autogenous mesenchymal stem cells were transplanted into a iatrogenic physeal defect in a lateral portion of the distal growth plate of the right femur. The same defect without stem cells transplantation in the left femoral distal physis served as a control. In our study, we used our own technique of implantation of MSCs with a newly modified gel scaffold (New Composite Hyaluronate/Collagen Type I/Fibrin Scaffold). The rabbits were euthanized 4 months after transplantation. Bone length discrepancy and valgus deformity were measured from femoral radiographs. Healing of the defect was investigated histologically. The ability of mesenchymal stem cells to survive and promote cartilage healing in the physeal defect was assessed by immunofluorescence. Average difference in femur length measured from surgery to euthanasia (4 months) was 0.61 ± 0.19 cm after preventive transplantation of MSCs in the right femur, but only 0.11 ± 0.07 cm in the left femur. Average angular (valgus) deformity of the right femur with MSCs preventively transplanted to iatrogenically damaged distal femoral physis was 1.2 ± 0.72 °. Valgus deformity in the left femur was 5.4 ± 2.5 °. Prophylactic transplantation of autogenous mesenchymal stem cells to iatrogenically damaged distal growth plate of the rabbit femur prevented a bone bridge formation and resulted in healing of the physeal defect with hyaline cartilage. Immunofluorescence examination showed that the chondrocytes newly formed in growth zone are the result of implanted MSCs differentiation. Femur growth in traumatized physis was maintained even after transplantation of autogenous MSCs. As compared with the opposite femur (with physeal defect but without transplanted MSCs), the bone showed no significant shortening or valgus deformity (p = 0.018)