Simple Sensor Application: Determination of Electrochemical Properties of Carvedilol in CPE Based on Zinc Oxide Nanoparticles and Development of the Method for its Determination in Pharmaceutical Samples

In the study, the electrochemical characteristics of carvedilol were determined by cyclic voltammetry and square wave voltammetry on carbon paste electrode with zinc oxide nanoparticles at pH 8.0 in Britton Robinson buffer. The adsorption characteristics of the molecule on the modified electrode and the electron number accompanying the electrode reaction were calculated. In addition, a new square wave anodic adsorptive stripping voltammetry process was suggested for the determination of carvedilol drug samples. The linear concentration range and detection limit of the process were found to be 0.07 µM–2.61 µM and 0.09 µM, respectively. Recovery studies of CAR in the pharmaceutical sample were performed to check the accuracy of the developed process. With the developed process, results with high reliability, reproduceability, accuracy and precision were obtained for the determination of CAR in pharmaceutical samples

An Exploratory Analysis of the Neural Correlates of Human-Robot Interactions With Functional Near Infrared Spectroscopy

Functional near infrared spectroscopy (fNIRS) has been gaining increasing interest as a practical mobile functional brain imaging technology for understanding the neural correlates of social cognition and emotional processing in the human prefrontal cortex (PFC). Considering the cognitive complexity of human-robot interactions, the aim of this study was to explore the neural correlates of emotional processing of congruent and incongruent pairs of human and robot audio-visual stimuli in the human PFC with fNIRS methodology. Hemodynamic responses from the PFC region of 29 subjects were recorded with fNIRS during an experimental paradigm which consisted of auditory and visual presentation of human and robot stimuli. Distinct neural responses to human and robot stimuli were detected at the dorsolateral prefrontal cortex (DLPFC) and orbitofrontal cortex (OFC) regions. Presentation of robot voice elicited significantly less hemodynamic response than presentation of human voice in a left OFC channel. Meanwhile, processing of human faces elicited significantly higher hemodynamic activity when compared to processing of robot faces in two left DLPFC channels and a left OFC channel. Significant correlation between the hemodynamic and behavioral responses for the face-voice mismatch effect was found in the left OFC. Our results highlight the potential of fNIRS for unraveling the neural processing of human and robot audio-visual stimuli, which might enable optimization of social robot designs and contribute to elucidation of the neural processing of human and robot stimuli in the PFC in naturalistic conditions

LOCALIZATION AND MORPHOMETRY OF MANDIBULAR FORAMEN

Foramen mandibulae, ramus mandibulae'nın orta kısmının arkasında bulunur, içinden nervus alveolaris inferior ve damarlar geçer. Amaç: Bu çalışmanın amacı, foramen mandibulae'nın morfometrik ölçümlerinin ve lokalizasyonunun belirlenmesidir. Gereç ve Yöntem: Bu çalışma 102 kuru mandibula'da yapıldı (204 taraf). Foramen mandibulae'larda altı ayrı morfometrik ölçüm yapıldı. Foramen mandibulae ile caput mandibulae, ramus mandibulae'nın arka kenarı, ramus mandibulae'nın ön kenarı, corpus mandibulae'nın alt kenarı, incisura mandibulae ve angulus mandibulae arası uzaklıklar ölçüldü. Bulgular: Foramen mandibulae ile caput mandibulae, ramus mandibulae'nın arka kenarı, ramus mandibulae'nın ön kenarı, corpus mandibulae'nın alt kenarı, incisura mandibulae'nın en derin noktası ve angulus mandibulae'nın en çıkıntılı noktası arası ortalama uzaklıklar sırasıyla, sağda 41,73 ± 3,97 mm; 14,32 ± 2,09 mm; 12,86 ± 2,46 mm; 29,51 ± 3,93 mm; 23,65 ± 3,38 mm; 22,80 ± 4,32 mm ve solda 41,36 ± 4,37 mm; 14,59 ± 2,13 mm; 12,77 ± 1,90 mm; 26,39 ± 4,05 mm; 24,18 ± 3,02 mm; 22,18 ± 3,90 mm olarak ölçüldü. Sağ ve sol taraf karşılaştırmasında foramen mandibulae ile incisura mandibulae'nın en derin noktası ve foramen mandibulae ile angulus mandibulae'nın en çıkıntılı noktası arası uzaklıkların ortalama değerleri anlamlı bir fark gösterdi. Sonuç: Foramen mandibulae'nın lokalizasyonu, mandibular anestezide, ağız içi girişimlerde, dentofasyal deformitelerin restorasyonunda ve maksillofasyal cerrahide önemlidir. Mandibular sinirin hasarından kaçınmak için bu bölge anatomisinin iyi bilinmesi gerekmektedir. Bu çalışmada, foramen mandibulae'nın morfometrik anatomisini ve lokalizasyonunu tanımlamaya çalıştık. Bu bilgilerden diş hekimliğinde, ağız içi, maksillofasyal cerrahide yararlanılabilir. Mandibular foramen is located just posterior to the middle of the ramus of mandible which transmits the inferior alveolar nerve and vessels. Objective of this study is to determine the localization and morphometric measurements of mandibular foramen. Material and methods: This study was conducted on 102 dry mandibles (204 sides). Six morphometric measurements were taken from mandibular foramen. The tances between mandibular foramen and head of mandible, posterior margin of ramus of mandible, anterior margin of ramus of mandible, inferior margin of mandibular body, the deepest point of mandibular notch and the most prominent point of mandibular angle were measured. Results: The average distances between mandibular foramen and head of mandible, mandibular foramen and posterior margin of ramus of mandible, mandibular foramen and anterior margin of ramus of mandible, mandibular foramen and inferior margin of mandibular body, mandibular foramen and the deepest point of mandibular notch and mandibular foramen and the most prominent point of mandibular angle were 41.73 ± 3.97 mm; 14.32 ± 2.09 mm; 12.86 ± 2.46 mm; 29.51 ± 3.93 mm; 23.65 ± 3.38 mm; 22.80 ± 4.32 mm on the right side and 41.36 ± 4.37 mm; 14.59 ± 2.13 mm; 12.77 ± 1.90 mm; 26.39 ± 4.05 mm; 24.18 ± 3.02 mm; 22.18 ± 3.90 mm on the left side, respectively. The correlation between distance of mandibular foramen - the deepest point of mandibular notch and mandibular foramen- the most prominent point of mandibular angle on the left and right side were showed significant difference. Conclusion: The localization of mandibular foramen is important in mandibular anesthesia, oral procedures, restoration of dentofacial deformities and maxillofacial surgery. It is necessary to know this anatomic area for avoiding to damage mandibular nerve. In this study, we tried to determine the localization and morphometric anatomy of mandibular foramen. These information may be helpful for oral procedures, maxillofacial surgery and dentistry

FEN BİLİMLERİ ENSTİTÜSÜ/LİSANSÜSTÜ TEZ PROJESİ

AMFİBİ İNSANSIZ HAVA ARACI TASARIMI VE ÜRETİM

Parametric investigation of hull shaped fuselage for an amphibious UAV

Performance of amphibious UAV’s (Unmanned Aerial Vehicles) that take off from and land on water, like seaplanes, greatly depend on hydrodynamic effects as well as aerodynamic effects, therefore their geometries need to be optimized. This study mainly investigates the effect of geometric parameters of a generic, hull-shaped fuselage that are constrained by hydrodynamic drivers, such as the step height needed to reduce hydrodynamic drag, and deadrise and sternpost angles needed for safe landing, on aerodynamic drag of the fuselage under cruise conditions by means of the commercial CFD code ANSYS Fluent. Study includes a comparison of the experimental [1] and numerical results obtained at angles of attack varying between 8° to 16° and with Spalart-Allmaras, k-ω and k-ε turbulence models.Amphibious UA

Synthesis, structure, and antimicrobial properties of mixed-metal organometallic polyoxometalates [Cp*2M5VO17](-) (M = Mo, W)

A series of Lindqvist-type polyoxometalate (POM) compounds [Cat][Cp*2M5VO17] (M = Mo (1), W (2)) were obtained from Cp*2M2O5 and NaVO3 in a 1:10 molar ratio in an acidic aqueous-methanol medium ([Cat]: Bu4P+ (1a, 2a), Bu4N+ (1b, 2b), Ph4P+ (1c, 2c), and BuNC5H5+ (1d, 2d)). They have been structurally characterized by H-1 and P-31 NMR, FT-IR, TGA, ESI, and elemental analysis techniques which support the proposed structures. In antibacterial studies, Ph4P[Cp*2Mo5VO17] (1c) is the compound that shows the highest antimicrobial activity against both gram-positive and gram-negativebacteria.This study has been granted by the Manisa Celal Bayar University Research Projects Coordination Office through Project Grant Number (2017-168).Manisa Celal Bayar University Research Projects Coordination Office [2017-168