Effective Design And Use Of Computer Decision Models.

This is the published version. Copyright 1980 MIS Quarterly.Computer decision models often provide useful results as management planning tools. However, these tools are frequently limited to firms with staffs of specialists who can assimilate the technical nature of the models. For other firms, the success of decision models such as simulation have not been demonstrated. This paper looks at recent literature regarding decision model deficiencies, evaluates selected financial simulation model packages, and suggests design needs for expanding the use of decision models to a broader range of firms. [ABSTRACT FROM AUTHOR] Copyright of MIS Quarterly is the property of MIS Quarterly & The Society for Information Management and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.

Information Technology and Sustained Competitive Advantage: A Resource-Based Analysis

This is the published version. Copyright 1995 MIS Quarterly.The concept of IT as a powerful competitive weapon has been strongly emphasized in the literature, yet the sustainability of the competitive advantage provided by IT applications is not well-explained. This work discusses the resource-based theory as a means of analyzing sustainability and develops a model founded on this resource-based view of the firm. This model is then applied to four attributes of IT -- capital requirements, proprietary technology, technical IT skills, and managerial IT skills -- which might be sources of sustained competitive advantage. From this resource-based analysis, we conclude that managerial IT skills is the only one of these attributes that can provide sustainability

Modulational instability of solitary waves in non-degenerate three-wave mixing: The role of phase symmetries

We show how the analytical approach of Zakharov and Rubenchik [Sov. Phys. JETP {\bf 38}, 494 (1974)] to modulational instability (MI) of solitary waves in the nonlinear Schr\"oedinger equation (NLS) can be generalised for models with two phase symmetries. MI of three-wave parametric spatial solitons due to group velocity dispersion (GVD) is investigated as a typical example of such models. We reveal a new branch of neck instability, which dominates the usual snake type MI found for normal GVD. The resultant nonlinear evolution is thereby qualitatively different from cases with only a single phase symmetry.Comment: 4 pages with figure

A Spontaneous Mutation in Contactin 1 in the Mouse

Mutations in the gene encoding the immunoglobulin-superfamily member cell adhesion molecule contactin1 (CNTN1) cause lethal congenital myopathy in human patients and neurodevelopmental phenotypes in knockout mice. Whether the mutant mice provide an accurate model of the human disease is unclear; resolving this will require additional functional tests of the neuromuscular system and examination of Cntn1 mutations on different genetic backgrounds that may influence the phenotype. Toward these ends, we have analyzed a new, spontaneous mutation in the mouse Cntn1 gene that arose in a BALB/c genetic background. The overt phenotype is very similar to the knockout of Cntn1, with affected animals having reduced body weight, a failure to thrive, locomotor abnormalities, and a lifespan of 2–3 weeks. Mice homozygous for the new allele have CNTN1 protein undetectable by western blotting, suggesting that it is a null or very severe hypomorph. In an analysis of neuromuscular function, neuromuscular junctions had normal morphology, consistent with previous studies in knockout mice, and the muscles were able to generate appropriate force when normalized for their reduced size in late stage animals. Therefore, the Cntn1 mutant mice do not show evidence for a myopathy, but instead the phenotype is likely to be caused by dysfunction in the nervous system. Given the similarity of CNTN1 to other Ig-superfamily proteins such as DSCAMs, we also characterized the expression and localization of Cntn1 in the retinas of mutant mice for developmental defects. Despite widespread expression, no anomalies in retinal anatomy were detected histologically or using a battery of cell-type specific antibodies. We therefore conclude that the phenotype of the Cntn1 mice arises from dysfunction in the brain, spinal cord or peripheral nervous system, and is similar in either a BALB/c or B6;129;Black Swiss background, raising a possible discordance between the mouse and human phenotypes resulting from Cntn1 mutations

NuSTAR SPECTROSCOPY OF GRS 1915+105: DISK REFLECTION, SPIN, AND CONNECTIONS TO JETS

We report on the results of spectral fits made to a NuSTAR observation of the black hole GRS 1915+105 in a "plateau" state. This state is of special interest because it is similar to the "low/hard" state seen in other black holes, especially in that compact, steady jets are launched in this phase. The 3-79 keV bandpass of NuSTAR, and its ability to obtain moderate-resolution spectra free from distortions such as photon pile-up, are extremely well suited to studies of disk reflection in X-ray binaries. In only 15 ks of net exposure, an extraordinarily sensitive spectrum of GRS 1915+105 was measured across the full bandpass. Ionized reflection from a disk around a rapidly spinning black hole is clearly required to fit the spectra; even hybrid Comptonization models including ionized reflection from a disk around a Schwarzschild black hole proved inadequate. A spin parameter of a = 0.98 ± 0.01 (1σ statistical error) is measured via the best-fit model; low spins are ruled out at a high level of confidence. This result suggests that jets can be launched from a disk extending to the innermost stable circular orbit. A very steep inner disk emissivity profile is also measured, consistent with models of compact coronae above Kerr black holes. These results support an emerging association between the hard X-ray corona and the base of the relativistic jet.United States. National Aeronautics and Space Administration (Contract NNG08FD06C

The Reflection Component from Cygnus X-1 in the Soft State Measured by NuSTAR and Suzaku

The black hole binary Cygnus X-1 was observed in late 2012 with the Nuclear Spectroscopic Telescope Array (NuSTAR) and Suzaku, providing spectral coverage over the ~1-300 keV range. The source was in the soft state with a multi-temperature blackbody, power law, and reflection components along with absorption from highly ionized material in the system. The high throughput of NuSTAR allows for a very high quality measurement of the complex iron line region as well as the rest of the reflection component. The iron line is clearly broadened and is well described by a relativistic blurring model, providing an opportunity to constrain the black hole spin. Although the spin constraint depends somewhat on which continuum model is used, we obtain ɑ_* > 0.83 for all models that provide a good description of the spectrum. However, none of our spectral fits give a disk inclination that is consistent with the most recently reported binary values for Cyg X-1. This may indicate that there is a >13° misalignment between the orbital plane and the inner accretion disk (i.e., a warped accretion disk) or that there is missing physics in the spectral models

CONSTRAINTS ON THE NEUTRON STAR AND INNER ACCRETION FLOW IN SERPENS X-1 USING

We report on an observation of the neutron star low-mass X-ray binary Serpens X-1, made with NuSTAR. The extraordinary sensitivity afforded by NuSTAR facilitated the detection of a clear, robust, relativistic Fe K emission line from the inner disk. A relativistic profile is required over a single Gaussian line from any charge state of Fe at the 5σ level of confidence, and any two Gaussians of equal width at the same confidence. The Compton back-scattering "hump" peaking in the 10-20 keV band is detected for the first time in a neutron star X-ray binary. Fits with relativistically blurred disk reflection models suggest that the disk likely extends close to the innermost stable circular orbit (ISCO) or stellar surface. The best-fit blurred reflection models constrain the gravitational redshift from the stellar surface to be z [subscript NS] ≥ 0.16. The data are broadly compatible with the disk extending to the ISCO; in that case, z [subscript NS] ≥ 0.22 and R [subscript NS] ≤ 12.6 km (assuming M [subscript NS] = 1.4 M [subscript ☉] and a = 0, where a = cJ/GM [superscript 2]). If the star is as large or larger than its ISCO, or if the effective reflecting disk leaks across the ISCO to the surface, the redshift constraints become measurements. We discuss our results in the context of efforts to measure fundamental properties of neutron stars, and models for accretion onto compact objects.United States. National Aeronautics and Space Administration (NASA Contract No. NNG08FD60C

Phytotoxicity of silver nanoparticles on Vicia faba: evaluation of particle size effects on photosynthetic performance and leaf gas exchange

Nanotechnology is an emerging field in science and engineering, which presents significant impacts on the economy, society and the environment. The nanomaterials’ (NMs) production, use, and disposal is inevitably leading to their release into the environment where there are uncertainties about its fate, behaviour, and toxicity. Recent works have demonstrated that NMs can penetrate, translocate, and accumulate in plants. However, studies about the effects of the NMs on plants are still limited because most investigations are carried out in the initial stage of plant development. The present study aimed to evaluate and characterize the photochemical efficiency of photosystem II (PSII) of broad bean (Vicia faba) leaves when subjected to silver nanoparticles (AgNPs) with diameters of 20, 51, and 73 nm as well as to micrometer-size Ag particles (AgBulk). The AgNPs were characterized by transmission electron microscopy and dynamic light scattering. The analyses were performed by injecting the leaves with 100 mg L-1 aqueous solution of Ag and measuring the chlorophyll fluorescence imaging, gas exchange, thermal imaging, and reactive oxygen species (ROS) production. In addition, silver ion (Ag+) release from Ag particles was determined by dialysis. The results revealed that AgNPs induce a decrease in the photochemical efficiency of photosystem II (PSII) and an increase in the non-photochemical quenching. The data also revealed that AgNPs affected the stomatal conductance (gs) and CO2 assimilation. Further, AgNPs induced an overproduction of ROS in Vicia faba leaves. Finally, all observed effects were particle diameter-dependent, increasing with the reduction of AgNPs diameter and revealing that AgBulk caused only a small or no changes on plants. In summary, the results point out that AgNPs may negatively affect the photosynthesis process when accumulated in the leaves, and that the NPs themselves were mainly responsible since negligible Ag+ release was detected

The Nuclear Spectroscopic Telescope Array (NuSTAR) High-Energy X-Ray Mission

The Nuclear Spectroscopic Telescope Array (NuSTAR) mission, launched on 2012 June 13, is the first focusing high-energy X-ray telescope in orbit. NuSTAR operates in the band from 3 to 79 keV, extending the sensitivity of focusing far beyond the ~10 keV high-energy cutoff achieved by all previous X-ray satellites. The inherently low background associated with concentrating the X-ray light enables NuSTAR to probe the hard X-ray sky with a more than 100-fold improvement in sensitivity over the collimated or coded mask instruments that have operated in this bandpass. Using its unprecedented combination of sensitivity and spatial and spectral resolution, NuSTAR will pursue five primary scientific objectives: (1) probe obscured active galactic nucleus (AGN) activity out to the peak epoch of galaxy assembly in the universe (at z lsim 2) by surveying selected regions of the sky; (2) study the population of hard X-ray-emitting compact objects in the Galaxy by mapping the central regions of the Milky Way; (3) study the non-thermal radiation in young supernova remnants, both the hard X-ray continuum and the emission from the radioactive element 44Ti; (4) observe blazars contemporaneously with ground-based radio, optical, and TeV telescopes, as well as with Fermi and Swift, to constrain the structure of AGN jets; and (5) observe line and continuum emission from core-collapse supernovae in the Local Group, and from nearby Type Ia events, to constrain explosion models. During its baseline two-year mission, NuSTAR will also undertake a broad program of targeted observations. The observatory consists of two co-aligned grazing-incidence X-ray telescopes pointed at celestial targets by a three-axis stabilized spacecraft. Deployed into a 600 km, near-circular, 6° inclination orbit, the observatory has now completed commissioning, and is performing consistent with pre-launch expectations. NuSTAR is now executing its primary science mission, and with an expected orbit lifetime of 10 yr, we anticipate proposing a guest investigator program, to begin in late 2014.Astronom