Electronic position indicator for latching solenoid valves

Electronic circuit connected to solenoid valve coils visually indicates the position of the valve stem. Transient suppression is provided to prevent damaging voltage spikes

Preliminary design study of a quiet, high flow fan (QHF) stage

Concepts selected to reduce fan generated noise in a turbofan are presented. Near-sonic flow at the fan inlet to reduce upstream propagated noise and the use of long-chord vanes to reduce downstream noise is discussed. The near-sonic condition at the rotor inlet plane was achieved by designing for high specific mass flow and by maintaining the high flow at reduced power by variable stators and variable fan exhaust nozzle. The long-chord vanes reduce response to unsteady flow. The acoustic design showed that long-chord stators would significantly reduce turbofan source noise and that other stator design parameters have no appreciable effect on noise for the spacing and chord length of the turbofan design. Four rig flow paths studied in the aerodynamic preliminary design are discussed. Noise prediction results indicate that a turbofan powered aircraft would be under federal air regulations levels without any acoustic treatment

Improving Water Quality Through BMPs For Crop Production Systems Whole Farm Soil and Water Management

The major objective of this demonstration project was to assess the usefulness of Global Positioning Systems/Geographic Information Systems (GPS/GIS), water testing, soil testing and yield monitoring in a whole farm water and soil management plan. An important part of this objective was to make recommendations to increase crop productivity and decrease the potential for surface water degradation through erosion and runoff at the farm. The farm was located on 2400 acres in the Bayou de View watershed in Monroe County, Arkansas. The farm lies approximately five miles southwest of the town of Brinkley straddling Highway 17 just south of its intersection with County Road 302 and with U. S. Highway 70. Slightly over 2200 acres were under cultivation and this was generally in a 1 :2 ratio of rice to soybeans, with approximately half of the soybean fields double-cropped with winter wheat each year

The Nature of Blue Cores in Spheroids: a Possible Connection with AGN and Star Formation

We investigate the physical nature of blue cores in early-type galaxies through the first multi-wavelength analysis of a serendipitously discovered field blue-nucleated spheroid in the background of the deep ACS/WFC griz multicolor observations of the cluster Abell 1689. The resolved g-r, r-i and i-z color maps reveal a prominent blue core identifying this galaxy as a ``typical'' case study, exhibiting variations of 0.5-1.0 mag in color between the center and the outer regions, opposite to the expectations of reddened metallicity induced gradients in passively evolved ellipticals. From a Magellan-Clay spectrum we secure the galaxy redshift at $z=0.624$. We find a strong X-ray source coincident with the spheroid galaxy. Spectral features and a high X-ray luminosity indicate the presence of an AGN in the galaxy. However, a comparison of the X-ray luminosity to a sample derived from the Chandra Deep Field South displays Lx to be comparable to Type I/QSO galaxies while the optical flux is consistent with a normal star-forming galaxy. We conclude that the galaxy's non-thermal component dominates at high-energy wavelengths while we associate the spheroid blue light with the stellar spectrum of normal star-forming galaxies. We argue about a probable association between the presence of blue cores in spheroids and AGN activity.Comment: Accepted for publication in the Astrophysical Journal. 6 pages, 3 figures. Full resolution images available at http://acs.pha.jhu.edu/~felipe/e-print

Nurses\u27 Alumnae Association Bulletin - Volume 4 Number 7

Welcome Home Jefferson Unit Honored by Army Sincere Thanks Treasurer Report Calendar of Events Graduate Nurses\u27 Chorus Lest You Forget Attention Hi-Light of the Alumnae Association Meetings Ambitions for Alumnae Association Notice! Items to Remember Baccalaureate Service Graduating Class Private Duty News Central Dressing Room and Transfusion Unit Card Party Held The Clara Melville Scholarship Fund Staff News Notes on Urologic Nursing Capping Exercises The Poet\u27s Corner Pylephlebitis Student Nurse\u27s View Point The Transfusion Unit Improvements in the Nurses\u27 Home Jefferson Medical College Hospital School of Nursing Faculty Nurses Taking Advanced Courses Nurses in Anesthesia The Student Nurses\u27 Loan Fund A New and Improved Department for Diseases of the Chest Miscellaneous Items Jefferson\u27s Main Kitchen Activities Medical College News Purchasing Procedures Pinky Patter Flash! Class of 1932 Condolences Positions Thirty-Eighth General Hospital Nurses\u27 Reunion Engagements Marriages New Arrivals Deaths The Bulletin Committee Attention Alumnae New Addresse

GABAergic Modulation of Inferior Colliculus Excitability: Role in the Ethanol Withdrawal Audiogenic Seizures

The role of the inferior colliculus and GABAeric transmission within this structure in the development of susceptibility to sound-induced seizures in ethanol-dependent rats was examined. Ethanol-dependent rats with bilateral electrolytic lesions which destroyed approximately 50.0 ± 6.4% of the inferior colliculus failed to exhibit susceptibility to sound-induced seizures. However, comparable medial geniculate body lesions (82.7 ± 2.7% complete) did not alter wild running, slightly reduced tonus and actually increased clonus susceptibility in rats treated similarly with ethanol. As reported previously, bilateral injection of either muscimol (43–263 pmol/site) or racemic baclofen (520–1580 pmol/site) into the inferior colliculus also suppressed seizure susceptibility. Other studies in ethanol-naive animals found that bilateral microinfusion of(+)-bicuculline methoiodide (2 or 20 pmol/min for up to 5 min) into the inferior colliculus induced wild running and clonus closely resembling sound-induced seizure responses in ethanol-dependent rats. Although similar microinjections of (+)-bicuculline methiodide (0.4 pmol/min for 5 min) into the inferior colliculus did not induce seizure activity directly, an increased susceptibility to sound-induced seizures was observed. Electrolytic lesions of the medial geniculate body did not block wild running responses induced by (+)-bicuculline methiodide, but slightly reduced clonus. Five-minute infusions of picrotoxin (200 pmol/min), Ro5-3663 (2000 pmol/min), kainic acid (20 or 200 pmol/min), strychnine (2000 pmol/min) or carbachol 2000 pmol/min) into the inferior colliculus of ethanol-naive rats all induced bicuculline-like seizures. Seizures induced by bicuculline methiodide, picrotoxin or Ro5-3663 occurred within 5 min after the start of infusions. Seizures induced by non-GABAergic drugs were delayed 10 to 15 min after beginning the infusions. Finally, muscimol (263 pmol/site) administered into the inferior colliculus blocked sound-induced seizures in Uaz:AGS (S.D.) epilepsy prone rats and prevented seizures induced by bicuculline or kainic acid infused into this brain site. However, seizure responses after i.v. bicuculline infusion or maximal electroshock were not diminished by injection of this dose of muscimol into the inferior colliculus. These results suggest that adaptation in GABAergic inhibitory mechanisms in the inferior colliculus could play an important role in the genesis of sound-induced seizures in ethanol-dependent rats, although additional mechanisms involving excitatory processes may also be important

Isolation of a SIR-like gene, SIR-T8, that is overexpressed in thyroid carcinoma cell lines and tissues

We used subtractive library screening to identify the changes that occur in gene expression during thyroid cell neoplastic transformation. Complementary DNA from normal thyroid cells (HTC 2) was subtracted from a complementary DNA library constructed from a human thyroid papillary carcinoma cell line. The library was screened for genes upregulated in human thyroid papillary carcinoma cell line cells, and several cDNA clones were isolated. One of these clones has a sirtuin core and high homology with the human silent information regulator protein family. This clone, designated ‘SIR-T8’, was overexpressed in human thyroid carcinoma cell lines and tissues, but not in adenomas. The human SIR-T8 protein has a molecular weight of 39 kDa and is primarily located in the cytoplasm under the nuclear membrane. The SIR-T8 gene is located on chromosome 17q25-1

Hominids adapted to metabolize ethanol long before human-directed fermentation

Paleogenetics is an emerging field that resurrects ancestral proteins from now-extinct organisms to test, in the laboratory, models of protein function based on natural history and Darwinian evolution. Here, we resurrect digestive alcohol dehydrogenases (ADH4) from our primate ancestors to explore the history of primate-ethanol interactions. The evolving catalytic properties of these resurrected enzymes show that our ape ancestors gained a digestive dehydrogenase enzyme capable of metabolizing ethanol near the time that they began using the forest floor, about 10 million y ago. The ADH4 enzyme in our more ancient and arboreal ancestors did not efficiently oxidize ethanol. This change suggests that exposure to dietary sources of ethanol increased in hominids during the early stages of our adaptation to a terrestrial lifestyle. Because fruit collected from the forest floor is expected to contain higher concentrations of fermenting yeast and ethanol than similar fruits hanging on trees, this transition may also be the first time our ancestors were exposed to (and adapted to) substantial amounts of dietary ethanol