72 research outputs found
Mirari Brass Quintet, Renewed, Reused, Recycled
Performing a wide wariety of works from Renaissance music to Charles Mingus, the Mirari Brass Quintet delight and inspire with their engaging and eclectic style of performance and bring a spirit of joyful collaboration and innovation to music spanning many centuries and genres. The commissioners of multiple new works for brass, the group performs a spectacular tight-rope act balancing intensity with levity and refined virtuosity with pure fun.https://digitalcommons.kennesaw.edu/musicprograms/1966/thumbnail.jp
Mechanisms of Odor-Tracking: Multiple Sensors for Enhanced Perception and Behavior
Early in evolution, the ability to sense and respond to changing environments must have provided a critical survival advantage to living organisms. From bacteria and worms to flies and vertebrates, sophisticated mechanisms have evolved to enhance odor detection and localization. Here, we review several modes of chemotaxis. We further consider the relevance of a striking and recurrent motif in the organization of invertebrate and vertebrate sensory systems, namely the existence of two symmetrical olfactory sensors. By combining our current knowledge about the olfactory circuits of larval and adult Drosophila, we examine the molecular and neural mechanisms underlying robust olfactory perception and extend these analyses to recent behavioral studies addressing the relevance and function of bilateral olfactory input for gradient detection. Finally, using a comparative theoretical approach based on Braitenberg's vehicles, we speculate about the relationships between anatomy, circuit architecture and stereotypical orientation behaviors
Learning to Noise: Application-Agnostic Data Sharing with Local Differential Privacy
The collection and sharing of individuals' data has become commonplace in
many industries. Local differential privacy (LDP) is a rigorous approach to
preserving data privacy even from a database administrator, unlike the more
standard central differential privacy. To achieve LDP, one traditionally adds
noise directly to each data dimension, but for high-dimensional data the level
of noise required for sufficient anonymization all but entirely destroys the
data's utility. In this paper, we introduce a novel LDP mechanism that
leverages representation learning to overcome the prohibitive noise
requirements of direct methods. We demonstrate that, rather than simply
estimating aggregate statistics of the privatized data as is the norm in LDP
applications, our method enables the training of performant machine learning
models. Unique applications of our approach include private novel-class
classification and the augmentation of clean datasets with additional
privatized features. Methods that rely on central differential privacy are not
applicable to such tasks. Our approach achieves significant performance gains
on these tasks relative to state-of-the-art LDP benchmarks that noise data
directly
MUSE spectroscopy and deep observations of a unique compact JWST target, lensing cluster CLIO
We present the results of a VLT MUSE/FORS2 and Spitzer survey of a unique compact lensing cluster CLIO at z = 0.42, discovered through the GAMA survey using spectroscopic redshifts. Compact and massive clusters such as this are understudied, but provide a unique prospective on dark matter distributions and for finding background lensed high-z galaxies. The CLIO cluster was identified for follow-up observations due to its almost unique combination of high-mass and dark matter halo concentration, as well as having observed lensing arcs from ground-based images. Using dual band optical and infra-red imaging from FORS2 and Spitzer, in combination with MUSE optical spectroscopy we identify 89 cluster members and find background sources out to z = 6.49. We describe the physical state of this cluster, finding a strong correlation between environment and galaxy spectral type. Under the assumption of an NFW profile, we measure the total mass of CLIO to be M200 = (4.49 ± 0.25) × 1014 M⊙. We build and present an initial strong-lensing model for this cluster, and measure a relatively low intracluster light (ICL) fraction of 7.21 ± 1.53 per cent through galaxy profile fitting. Due to its strong potential for lensing background galaxies and its low ICL, the CLIO cluster will be a target for our 110 h James Webb Space Telescope ‘Webb Medium-Deep Field’ (WMDF) GTO program.Publisher PDFPeer reviewe
Erratum to: Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue
This study provides a parallel characterization of the cytokine and chemokine response to stroke in the human and mouse brain at different stages of infarct resolution. The study goal was to address the hypothesis that chronic inflammation may contribute to stroke-related dementia. We used C57BL/6 and BALB/c mice to control for strain related differences in the mouse immune response. Our data indicate that in both mouse strains, and humans, there is increased granulocyte macrophage colony-stimulating factor (GM-CSF), interleukin-6 (IL-6), interleukin-12 p70 (IL-12p70), interferon gamma-induced protein-10 (IP-10), keratinocyte chemoattractant/interleukin-8 (KC/IL-8), monocyte chemoattractant protein-1 (MCP-1), macrophage inflammatory protein-1 alpha (MIP-1 alpha), macrophage inflammatory protein-1 beta (MIP-1 beta), regulated on activation, normal T cell expressed and secreted (RANTES), and Tumor necrosis factor-alpha (TNF-alpha) in the infarct core during the acute time period. Nevertheless, correlation and two-way ANOVA analyses reveal that despite this substantial overlap between species, there are still significant differences, particularly in the regulation of granulocyte colony-stimulating factor (G-CSF), which is increased in mice but not in humans. In the weeks after stroke, during the stage of liquefactive necrosis, there is significant resolution of the inflammatory response to stroke within the infarct. However, CD68+ macrophages remain present, and levels of IL-6 and MCP-1 remain chronically elevated in infarcts from both mice and humans. Furthermore, there is a chronic T cell response within the infarct in both species. This response is differentially polarized towards a T helper 1 (Th1) response in C57BL/6 mice, and a T helper 2 (Th2) response in BALB/c mice, suggesting that the chronic inflammatory response to stroke may follow a different trajectory in different patients. To control for the fact that the average age of the patients used in this study was 80 years, they were of both sexes, and many had suffered from multiple strokes, we also present findings that reveal how the chronic inflammatory response to stroke is impacted by age, sex, and multiple strokes in mice. Our data indicate that the chronic cytokine and chemokine response to stroke is not substantially altered in 18-month old compared to 3-month old C57BL/6 mice, although T cell infiltration is attenuated. We found a significant correlation in the chronic cytokine response to stroke in males and females. However, the chronic cytokine response to stroke was mildly exacerbated by a recurrent stroke in both C57BL/6 and BALB/c mice.NIA NIH HHS [P30 AG019610]; NINDS NIH HHS [U24 NS072026]; NINR NIH HHS [K99 NR013593]This item from the UA Faculty Publications collection is made available by the University of Arizona with support from the University of Arizona Libraries. If you have questions, please contact us at [email protected]
Recommended from our members
Inflation and Dark Energy from spectroscopy at z > 2
The expansion of the Universe is understood to have accelerated during two
epochs: in its very first moments during a period of Inflation and much more
recently, at z < 1, when Dark Energy is hypothesized to drive cosmic
acceleration. The undiscovered mechanisms behind these two epochs represent
some of the most important open problems in fundamental physics. The large
cosmological volume at 2 < z < 5, together with the ability to efficiently
target high- galaxies with known techniques, enables large gains in the
study of Inflation and Dark Energy. A future spectroscopic survey can test the
Gaussianity of the initial conditions up to a factor of ~50 better than our
current bounds, crossing the crucial theoretical threshold of
of order unity that separates single field and
multi-field models. Simultaneously, it can measure the fraction of Dark Energy
at the percent level up to , thus serving as an unprecedented test of
the standard model and opening up a tremendous discovery space
A Strong-Lensing Model for the WMDF JWST/GTO Very Rich Cluster Abell 1489
We present a first strong-lensing model for the galaxy cluster RM
J121218.5+273255.1 (; hereafter RMJ1212; also known as Abell 1489).
This cluster is amongst the top 0.1\% richest clusters in the redMaPPer
catalog; it is significantly detected in X-ray and through the
Sunyaev-Zel'dovich effect in ROSAT and \emph{Planck} data, respectively; and
its optical luminosity distribution implies a very large lens, following
mass-to-light scaling relations. Based on these properties it was chosen for
the Webb Medium Deep Fields (WMDF) JWST/GTO program. In preparation for this
program, RMJ1212 was recently imaged with GMOS on Gemini North and in seven
optical and near-infrared bands with the \emph{Hubble Space Telescope}. We use
these data to map the inner mass distribution of the cluster, uncovering
various sets of multiple images. We also search for high-redshift candidates in
the data, as well as for transient sources. We find over a dozen high-redshift
() candidates based on both photometric redshift and the dropout
technique. No prominent () transients were found in the data
between the two HST visits. Our lensing analysis reveals a relatively large
lens with an effective Einstein radius of
(), in broad agreement with the scaling-relation expectations. RMJ1212
demonstrates that powerful lensing clusters can be selected in a robust and
automated way following the light-traces-mass assumption.Comment: 17 pages, 6 figures, 2 tables; To be submitte
PEARLS: Low Stellar Density Galaxies in the El Gordo Cluster Observed with JWST
A full understanding of how unusually large "Ultra Diffuse Galaxies" (UDGs)
fit into our conventional understanding of dwarf galaxies remains elusive,
despite the large number of objects identified locally. A natural extension of
UDG research is the study of similar galaxies at higher redshift to establish
how their properties may evolve over time. However, this has been a challenging
task given how severely systematic effects and cosmological surface brightness
dimming inhibit our ability to study low-surface brightness galaxies at
high-. Here, we present an identification of low stellar surface density
galaxies (LDGs), likely the progenitors of local UDGs, at moderate redshift
with deep near-IR observations of the El Gordo cluster at with JWST.
By stacking 8 NIRCAM filters, we are able to achieve an apparent surface
brightness sensitivity of mag arcsec, faint enough to be
complete to the bright end of the LDG population. Our analysis identifies
significant differences between this population and local UDGs, such as their
color and size distributions, which suggest that UDG progenitors are bluer and
more extended at high- than at . This suggests that multiple
mechanisms are responsible for UDG formation and that prolonged transformation
of cluster dwarfs is not a primary UDG formation mechanism at high-.
Furthermore, we find a slight overabundance of LDGs in El Gordo, and, in
contrast to findings in local clusters, our analysis does not show a deficit of
LDGs in the center of El Gordo, implying that tidal destruction of LDGs is
significant between and .Comment: Resubmitted to ApJ after minor revision
Magellanic System Stars Identified in the SMACS J0723.3-7327 JWST ERO Images
We identify 68 distant stars in JWST/NIRCam ERO images of the field of galaxy
cluster SMACS J0723.3-7327 (SMACS 0723). Given the relatively small
() angular separation between SMACS 0723 and the Large
Magellanic Cloud, it is likely that these stars are associated with the LMC
outskirts or Leading Arm. This is further bolstered by a spectral energy
distribution analysis, which suggests an excess of stars at a physical distance
of kpc, consistent with being associated with or located behind the
Magellanic system. In particular, we find that the overall surface density of
stars brighter than 27.0 mag in the field of SMACS 0723 is 2.3 times that
of stars in a blank field with similar galactic latitude (the North Ecliptic
Pole Time Domain Field), and that the density of stars in the SMACS 0723 field
with SED-derived distances consistent with the Magellanic system is 7.3
times larger than that of the blank field. The candidate stars at these
distances are consistent with a stellar population at the same distance modulus
with [Fe/H] and an age of Gyr. On the assumption that all
of the 68 stars are associated with the LMC, then the stellar density of the
LMC at the location of the SMACS 0723 field is stars kpc,
which helps trace the density of stars in the LMC outskirts.Comment: Submitted to ApJ, comments welcom
EC85-219 1985 Nebraska Swine Report
This 1985 Nebraska Swine Report was prepared by the staff in Animal Science and cooperating departments for use in the Extension and Teaching programs at the University of Nebraska-Lincoln. Authors from the following areas contributed to this publication: Swine Nutrition, swine diseases, pathology, economics, engineering, swine breeding, meats, agronomy, and diagnostic laboratory. It covers the following areas: breeding, disease control, feeding, nutrition, economics, housing and meats
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