248 research outputs found

    Study of the Collective Dynamics of Liquid Ni Using Pseudo-Potential Theory

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    The Phonon dispersion curves of liquid Ni near its melting temperature have been investigated using two different models: Takeno-Goda and Hubbard-Beeby. Bretonnet-Silbert (BS) pseudo-potential has been used for the interatomic potential calculation. The pair distribution function g(r) obtained by Variational Modified Hypernatted Chain (VMHNC) method. The phonon dispersion data thus obtained is in good agreement with those of Gopala et al. Also the first minimum in (k) for longitudinal phonon modes and the first maximum in the static factor S(k) occur nearly at the same value of k according to the framework of Ziman’s Formalism. In addition, stiffness constants (C11 and C44) and compressibility have been calculated and compared with the available experimental data

    Design of a dedicated circular coil for Magnetic Resonance Spectroscopy studies in small phantoms and animal acquisition with a 3 Tesla Magnetic Resonance clinical scanner

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    Abstract Introduction: Magnetic Resonance Spectroscopy (MRS) is a very powerful tool to explore the tissue components, by allowing a selective identification of molecules and molecular distribution mapping. Due to intrinsic Signal-to-Noise Ratio limitations (SNR), MRS in small phantoms and animals with a clinical scanner requires the design and development of dedicated radiofrequency (RF) coils, a task of fundamental importance. In this article, the authors describe the simulation, design, and application of a 1H transmit/receive circular coil suitable for MRS studies in small phantoms and small animal models with a clinical 3T scanner. In particular, the circular coil could be an improvement in animal experiments for tumor studies in which the lesions are localized in specific areas. Material and methods: The magnetic field pattern was calculated using the Biot–Savart law and the inductance was evaluated with analytical calculations. Finally, the coil sensitivity was measured with the perturbing sphere method. Successively, a prototype of the coil was built and tested on the workbench and by the acquisition of MRS data. Results: In this work, we demonstrate the design trade-offs for successfully developing a dedicated coil for MRS experiments in small phantoms and animals with a clinical scanner. The coil designed in the study offers the potential for obtaining MRS data with a high SNR and good spectral resolution. Conclusions: The paper provides details of the design, modelling, and construction of a dedicated circular coil, which represents a low cost and easy to build answer for MRS experiments in small samples with a clinical scanner

    A Practical Guide to Estimating Coil Inductance for Magnetic Resonance Applications

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    Radiofrequency (RF) coils are employed to transmit and/or receive signals in Magnetic Resonance (MR) systems. The design of home-made, organ-specific RF coils with optimized homogeneity and/or Signal-to-Noise Ratio (SNR) can be a plus in many research projects. The first step requires accurate inductance calculation, this depending on the conductor's geometry, to later define the tuning capacitor necessary to obtain the desired resonance frequency. To fulfil such a need it is very useful to perform a priori inductance estimation rather than relying on the time-consuming trial-and-error approach. This paper describes and compares two different procedures for coil inductance estimation to allow for a fast coil-prototyping process. The first method, based on calculations in the quasi-static approximation, permits an investigation on how the cross-sectional geometry of the RF coil conductors affects the total inductance and can be easily computed for a wide variety of coil geometries. The second approach uses a numerical full-wave method based on the Finite-Difference Time-Domain (FDTD) algorithm, and permits the simulation of RF coils with any complex geometry, including the case of multi-element phased array. Comparison with workbench measurements validates both the analytical and numerical results for RF coils operating within a wide field range (0.18–7 T)

    Paleoecology and proliferation of the bivalve Chondrodonta joannae (Choffat) in the upper Cenomanian (Upper Cretaceous) Adriatic Carbonate Platform of Istria (Croatia)

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    Chondrodonta joannae (Choffat) is a morphologically variable oyster-like bivalve with a predominately calcitic shell. An exceptional exposure of C. joannae-bearing strata of late Cenomanian age crops out along the seaside in northern Istria (Croatia) and permits a taphonomical and functional analysis in order to define the life habit and growth strategies of this bivalve. The C. joannae population from the studied succession is characterized by highly-elongated, large and curved shells, reaching about 50 cm in height and 5 cm in length. This shell shape is typical of the club-like bivalve morphotype, which was adapted to soft-bottom substrates with high sediment accumulation. The shell is slightly inequivalve and characterized by a reduced body cavity, a few centimetres high, and a dorsal region up to 10 times longer. The shell opening mechanism was mostly based on the resilium located between the chondrophores which protrude in the body cavity. The abandoned dorsal cavity is filled by a calcite hinge plate, the ventral edge of which acted as fulcrum for the valve flexibility. In the hinge plate, the function of chondrophores changed. They acted as a hinge to keep tightly interlocked the valves, which considerably emerged above the sediment-water interface. The individuals were arranged in low shrub-type congregations, which produced low-relief mounds. The functional morphology and taphonomic signature suggest that C. joannae individuals collected food at a greater distance from the bottom with respect to the co-occurring rudists. We speculate that the C. joannae proliferation could be related to a late Cenomanian phase of environmental instability predating the OAE2 with fluctuating climatic conditions and ocean fertility

    Strontium isotope stratigraphy of late Cenozoic fossiliferous marine deposits in North Borneo (Brunei, and Sarawak, Malaysia)

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    Neogene marine deposits of North Borneo are locally very rich in fossils that provide glimpses into the past biodiversity. However, dating these onshore sediments with biostratigraphy is often hampered by the lack and/or the poor preservation state of index fossils. Therefore, the fossiliferous sites were targeted with strontium isotope stratigraphy (SIS) to obtain higher precision relative dating. Well-preserved macrofossils were screened using a multidisciplinary approach, and 87Sr/86Sr ratios of the most pristine remains were used to date the embedding sediments. Most of the measured ages fall in the expected chronostratigraphic framework established by large scale studies for the region. The oldest, Burdigalian (early Miocene) ages were measured for the Sibuti Formation in Sarawak (17.71 \ub1 0.2My and 16.7 \ub1 0.2My) followed by a Serravallian (middle Miocene) age within the Belait Fm in Brunei (12.1 +1.4/-1.2My). Eight localities from the younger units, the Miri and Seria formations in Brunei, gave a range in age from 10.5 \ub1 1 to 7.0 +0.9/-0.5My (Tortonian-Messinian). Reworked fossil assemblages from Tutong beach were also investigated and the SIS ages of Late Miocene support an origin from the younger part of the Seria Fm. One locality, in Lumapas where limestone crops out in Brunei, gave an unexpected younger age (Tortonian, late Miocene, 10.6 \ub1 1My) compared to estimates projected for its assumed stratigraphic position in the lower Belait Formation (late Burdigalian). These challenging data require more research, yet if the young age is accepted, the stratigraphic situation of the limestone needs further revision

    Towards cot-side mapping of the sensorimotor cortex in preterm and term infants with wearable high-density diffuse optical tomography

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    We are translating wearable HD-DOT to the neonatal clinic to investigate healthy and brain-injured infants and establish a model of the developmental trajectory of the infant sensorimotor system

    The degeneration of locus coeruleus occurring during Alzheimer’s disease clinical progression: a neuroimaging follow-up investigation

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    \ua9 The Author(s) 2024.The noradrenergic nucleus Locus Coeruleus (LC) is precociously involved in Alzheimer’s Disease (AD) pathology, and its degeneration progresses during the course of the disease. Using Magnetic Resonance Imaging (MRI), researchers showed also in vivo in patients the disruption of LC, which can be observed both in Mild Cognitively Impaired individuals and AD demented patients. In this study, we report the results of a follow-up neuroradiological assessment, in which we evaluated the LC degeneration overtime in a group of cognitively impaired patients, submitted to MRI both at baseline and at the end of a 2.5-year follow-up. We found that a progressive LC disruption can be observed also in vivo, involving the entire nucleus and associated with clinical diagnosis. Our findings parallel neuropathological ones, which showed a continuous increase of neuronal death and volumetric atrophy within the LC with the progression of Braak’s stages for neurofibrillary pathology. This supports the reliability of MRI as a tool for exploring the integrity of the central noradrenergic system in neurodegenerative disorders

    Chronostratigraphy of the Barremian-Early Albian of the Maestrat Basin (E Iberian Peninsula): integrating strontium-isotope stratigraphy and ammonoid biostratigraphy

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    A revised chronostratigraphy of the Barremian - Early Albian sedimentary record of the Maestrat Basin (E Iberian Peninsula) is provided based on a comprehensive synthesis of previous biostratigrahic data, a new ammonoid finding and numerical ages derived from 87Sr/86Sr values measured on shells of rudists, oysters and brachiopods. The succession, which comprises eight lithostratigraphic formations, is arranged into six major transgressive-regressive sequences and plotted against numerical ages, geomagnetic polarity chrons, ammonoid zones and the stratigraphic distribution of age-diagnostic ammonoids, orbitolinid fora- minifera and rudist bivalves. The oldest lithostratigraphic unit sampled, the marine Artoles Formation, is Early to Late Barremian. Above, the dinosaur-bearing deposits of the Morella Formation and its coastal to shallow-marine equivalent, the Cervera del Maestrat Formation, are of Late Barremian age and span at least part of the Imerites giraudi ammonoid zone. 87Sr/ 86Sr ratios from oyster shells in the upper part of the overlying marine Xert Formation are consistent with a latest Barremian-earliest Aptian age, while an ammonite belonging to the Late Barremian Martelites sarasini Zone was collected within the lowermost part of this lat- ter formation. The Barremian-Aptian boundary is tentatively placed close above the base of the succeeding transgressive marls of the Forcall Formation by analogy with nearby Tethyan basins, where major transgres- sive records contain latest Barremian ammonoids in their basal parts. The rest of the Forcall Formation and the platform carbonates of the Villarroya de los Pinares Formation are of Early Aptian age. The transition from the Barremian into the Aptian occurred in the course of a wide transgression, which was accompanied by the proliferation of Palorbitolina lenticularis. This transgressive event drowned Late Barremian carbonate platforms (Xert Formation) throughout the basin. Extensive carbonate platforms (Villarroya de los Pinares Formation) recovered coevally with a post-OAE 1a late Early Aptian major regression of relative sea level. The last lithostratigraphic unit analyzed, the marine Benassal Formation, spans the terminal Early Aptian- Late Aptian interval. Based on ammonite distributions, the lower part of the overlying coastal to continental coal-bearing Escucha Formation is Early Albian in age. This improved chronostratigraphic knowledge allows a more precise correlation of the sedimentary record studied with other coeval successions worldwide

    Atherfieldastacus rapax (Harbort, 1905) (Glypheidae, Mecochiridae) from the Lower Cretaceous of the Maestrat Basin (NE Spain)

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    Three specimens of the lobster 'Meyeria rapax', which represent the first record of this species in Spain, were collected in the Artoles Formation cropping out in the surroundings of the town of Ares del Maestrat in the Maestrat Basin. Microfacies and paleontological analyses of the sedimentary succession containing the fossil lobsters allow us to infer a near-coastal depositional setting. Numerical ages derived from Sr-isotope analyses combined with previous chronostratigraphic studies of the Artoles Formation suggest an early Barremian age for the stratigraphic interval, which is located around the middle part of the formation, with lobsters studied. The study of the morphological features observed in the record of the 'Meyeria rapax' specimens from Spain supports the ascription of the species to the new genus Atherfieldastacus proposed recently for the Mecochiridae family

    Simulation, design, and test of an elliptical surface coil for magnetic resonance imaging and spectroscopy

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    AbstractThe simplest design of surface coils for magnetic resonance imaging (MRI) applications is circular and square loops, both producing a magnetic field perpendicular to the coil plane in the central region‐of‐interest (ROI), with an amplitude that decreases along the coil axis. However, a surface coil constituted by a loop with different geometry could be necessary when particular field‐of‐views (FOVs) are desired, especially for performing imaging in an elongated region. This can be achieved by using an elliptical loop, which can guarantee a wide longitudinal FOV and a good penetration in deep sample regions. This work proposes the application of a method for elliptical coil Signal‐to‐Noise Ratio (SNR) estimation previously developed for circular and square loop design, in which coil inductance and resistance are analytically calculated and the magnetic field pattern is estimated using the magnetostatic approach, while the sample‐induced resistance is calculated with the vector potential calculation method. In the second part of the paper, we propose the simulation and the design of a transmit/receive elliptical coil for MRI in mice with a 3T clinical scanner. We also evaluated the coil performance in a preliminary magnetic resonance spectroscopy (MRS) study in phantom
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