Drag force in a string model dual to large-N QCD

We compute the drag force exerted on a quark and a di-quark systems in a background dual to large-N QCD at finite temperature. We find that appears a drag force in the former setup with flow of energy proportional to the mass of the quark while in the latter there is no dragging as in other studies. We also review the screening length.Comment: 15 pages, typos removed, error corrected, refs adde

The stress tensor of a quark moving through N=4 thermal plasma

We develop the linear equations that describe graviton perturbations of AdS_5-Schwarzschild generated by a string trailing behind an external quark moving with constant velocity. Solving these equations allows us to evaluate the stress tensor in the boundary gauge theory. Components of the stress tensor exhibit directional structures in Fourier space at both large and small momentum. We comment on the possible relevance of our results to relativistic heavy ion collisions.Comment: 33 pages, 5 figures. v2: improved low K discussion; other minor improvement

Cancer cachexia

In recent years many efforts of researchers and clinicians were made to improve our knowledge of cachexia syndrome. Not only cancer, but also many chronic or end-stage diseases such as AIDS, chronic obstructive pulmonary disease (COPD), rheumatoid arthritis, tuberculosis and Crohn's disease are associated with cachexia, a condition of abnormally low weight, weakness, and general bodily decline which deteriorates quality of life and reduces the prognosis of the patients who suffer from it. In the present editorial we will focus cachexia related on cancer and provide some insight into this prognosis-limiting syndrome

No-Drag String Configurations for Steadily Moving Quark-Antiquark Pairs in a Thermal Bath

We investigate the behavior of stationary string configurations on a five-dimensional AdS black hole background which correspond to quark-antiquark pairs steadily moving in an N=4 super Yang-Mills thermal bath. There are many branches of solutions, depending on the quark velocity and separation as well as on whether Euclidean or Lorentzian configurations are examined.Comment: references added; statements corrected; eliminated computation of jet quenching parameter from Wilson loop of [Liu, Rajagopal, Wiedemann, hep-th/0605178] using Euclidean string configurations since those authors advocate [hep-th/0607062, footnote 14] the use of spacelike Lorentzian string configurations instea

Міжнародна наукова конференція «Шляхи розвитку науково-технічного співробітництва Росії, України і Білорусі»

7 жовтня 2011 року у Москві, у приміщенні Президії РАН на Ленінському проспекті 32А, відбулася міжнародна наукова конференція «Шляхи розвитку науково-технічного співробітництва Росії, України і Білорусі». Конференція була організована Інститутом проблем розвитку науки РАН (ІПРАН РАН) за підтримки Президії РАН. У ролі партнерської організації1виступив Російський гуманітарний науковий фонд

Dissipation from a heavy quark moving through N=4 super-Yang-Mills plasma

Using AdS/CFT, we compute the Fourier space profile of generated by a heavy quark moving through a thermal plasma of strongly coupled N=4 super-Yang-Mills theory. We find evidence of a wake whose description includes gauge fields with large momenta. We comment on the possible relevance of our results to relativistic heavy ion collisions.Comment: 17 pages, 2 figures. v2: reference added, other minor improvements. v3: improved the phrasing describing directional structure

Drag Force in a Charged N=4 SYM Plasma

Following recent developments, we employ the AdS/CFT correspondence to determine the drag force exerted on an external quark that moves through an N=4 super-Yang-Mills plasma with a non-zero R-charge density (or, equivalently, a non-zero chemical potential). We find that the drag force is larger than in the case where the plasma is neutral, but the dependence on the charge is non-monotonic.Comment: 16 pages, 1 eps figure; v2: references added, typos fixed; v3: more general ansatz, new nontrivial solution obtained, nonmonotonicity of the drag force made explicit in new figure, version to appear in JHE

Behavioral Deficits and Axonal Injury Persistence after Rotational Head Injury Are Direction Dependent

Pigs continue to grow in importance as a tool in neuroscience. However, behavioral tests that have been validated in the rodent model do not translate well to pigs because of their very different responses to behavioral stimuli. We refined metrics for assessing porcine open field behavior to detect a wide spectrum of clinically relevant behaviors in the piglet post-traumatic brain injury (TBI). Female neonatal piglets underwent a rapid non-impact head rotation in the sagittal plane (n=8 evaluable) or were instrumented shams (n=7 evaluable). Open field testing was conducted 1 day prior to injury (day −1) in order to establish an individual baseline for analysis, and at days +1 and +4 after injury. Animals were then killed on day +6 after injury for neuropathological assessment of axonal injury. Injured piglets were less interested in interacting with environmental stimuli and had a lower activity level than did shams. These data were compared with previously published data for axial rotational injuries in neonatal piglets. Acute behavioral outcomes post-TBI showed a dependence on the rotational plane of the brain injury, with animals with sagittal injuries demonstrating a greater level of inactivity and less random usage of the open field space than those with axial injuries. The persistence of axonal injury is also dependent on the rotational plane, with sagittal rotations causing more prolonged injuries than axial rotations. These results are consistent with animal studies, finite element models, and studies of concussions in football, which have all demonstrated differences in injury severity depending upon the direction of head impact rotation

The Role of PPARγ Receptors and Leukotriene B4 Receptors in Mediating the Effects of LY293111 in Pancreatic Cancer

Pancreatic cancer is a devastating disease in which current therapies are inadequate. Separate lines of research have identified the 5-lipoxygenase/leukotriene B4 receptor pathway and the PPARγ pathway as potential targets for prevention or treatment of this disease. LY293111 was originally designed as a potent leukotriene B4 receptor antagonist for treatment of inflammatory conditions. LY293111 was also known to have inhibitory effects on 5-lipoxygenase, which is upstream of the production of leukotrienes. LY293111 was shown to have potent anticancer effects in pancreatic cancer and several other solid malignancies, where it caused cell cycle arrest and marked apoptosis. Subsequently, it came to light that LY293111 exhibited PPARγ agonist activity in addition to its effects on the 5-lipoxygenase pathway. This raises the question of which of the two targets is of greatest importance with regard to the anticancer effects of this agent. The evidence to date is not conclusive, but suggests that the effects of LY293111 may be mediated by both LTB4 receptors and PPARγ

A proposal for a new clinical classification of chronic pancreatitis

<p>Abstract</p> <p>Background</p> <p>The clinical course of chronic pancreatitis is still unpredictable, which relates to the lack of the availability of a clinical classification. Therefore, patient populations cannot be compared, the course and the outcome of the disease remain undetermined in the individual patient, and treatment is not standardized.</p> <p>Aim</p> <p>To establish a clinical classification for chronic pancreatitis which is user friendly, transparent, relevant, prognosis- as well as treatment-related and offers a frame for future disease evaluation.</p> <p>Methods</p> <p>Diagnostic requirements will include one clinical criterion, in combination with well defined imaging or functional abnormalities.</p> <p>Results</p> <p>A classification system consisting of three stages (A, B and C) is presented, which fulfils the above-mentioned criteria. Clinical criteria are: pain, recurrent attacks of pancreatitis, complications of chronic pancreatitis (e.g. bile duct stenosis), steatorrhea, and diabetes mellitus. Imaging criteria consist of ductal or parenchymal changes observed by ultrasonography, ERCP, CT, MRI, and/or endosonography.</p> <p>Conclusion</p> <p>A new classification of chronic pancreatitis, based on combination of clinical signs, morphology and function, is presented. It is easy to handle and an instrument to study and to compare the natural course, the prognosis and treatment of patients with chronic pancreatitis.</p