1,744 research outputs found
Tropospheric limitations on the accuracy of phase measurement of coordinates in astronomy
The effect of tropospheric fluctuation on the accuracy of phase measurements of coordinates is discussed. The nature of the averaging of the tropospheric effects, if N coordinate measurements of duration T with period mu are made, is investigated. Various averaging modes depending on the relation of the various time parameters are investigated. Equations taking into account the correlations between individual observations are presented. It is shown that the correlation interval between the individual observations is always greater than the fluctuation period of tropospheric inhomogeneities typical for a given baseline
Versioning of Digital Objects in a Fedora-based Repository
This presentation gives an overview on the complex versioning re-quirements for digital objects in the scope of the project eSciDoc and discusses our solution based on the flexible repository architecture Fedora. It describes the conceptual background of how the eSciDoc infrastructure handles versioning of digital objects. Versioning and object identification are strongly interwoven concepts. Therefore, the unique identification of objects and their versions are discussed as well
Metastatic Melanomas Express Inhibitory Low Affinity Fc Gamma Receptor and Escape Humoral Immunity
Our research, inspired by the pioneering works of Isaac Witz in the 1980s, established that 40% of human metastatic melanomas express ectopically inhibitory Fc gamma receptors (FcγRIIB), while they are detected on less than 5% of primary cutaneous melanoma and not on melanocytes. We demonstrated that these tumoral FcγRIIB act as decoy receptors that bind the Fc portion of antimelanoma IgG, which may prevent Fc recognition by the effector cells of the immune system and allow the metastatic melanoma to escape the humoral/natural immune response. The FcγRIIB is able to inhibit the ADCC (antibody dependent cell cytotoxicity) in vitro. Interestingly, the percentage of melanoma expressing the FcγRIIB is high (70%) in organs like the liver, which is rich in patrolling NK (natural killer) cells that exercise their antitumoral activity by ADCC. We found that this tumoral FcγRIIB is fully functional and that its inhibitory potential can be triggered depending on the specificity of the anti-tumor antibody with which it interacts.
Together these observations elucidate how metastatic melanomas interact with and potentially evade humoral immunity and provide direction for the improvement of anti-melanoma monoclonal antibody therapy
Stability of quantized time-delay nonlinear systems: A Lyapunov-Krasowskii-functional approach
Lyapunov-Krasowskii functionals are used to design quantized control laws for
nonlinear continuous-time systems in the presence of constant delays in the
input. The quantized control law is implemented via hysteresis to prevent
chattering. Under appropriate conditions, our analysis applies to stabilizable
nonlinear systems for any value of the quantization density. The resulting
quantized feedback is parametrized with respect to the quantization density.
Moreover, the maximal allowable delay tolerated by the system is characterized
as a function of the quantization density.Comment: 31 pages, 3 figures, to appear in Mathematics of Control, Signals,
and System
Owl and Lizard: Patterns of Head Pose and Eye Pose in Driver Gaze Classification
Accurate, robust, inexpensive gaze tracking in the car can help keep a driver
safe by facilitating the more effective study of how to improve (1) vehicle
interfaces and (2) the design of future Advanced Driver Assistance Systems. In
this paper, we estimate head pose and eye pose from monocular video using
methods developed extensively in prior work and ask two new interesting
questions. First, how much better can we classify driver gaze using head and
eye pose versus just using head pose? Second, are there individual-specific
gaze strategies that strongly correlate with how much gaze classification
improves with the addition of eye pose information? We answer these questions
by evaluating data drawn from an on-road study of 40 drivers. The main insight
of the paper is conveyed through the analogy of an "owl" and "lizard" which
describes the degree to which the eyes and the head move when shifting gaze.
When the head moves a lot ("owl"), not much classification improvement is
attained by estimating eye pose on top of head pose. On the other hand, when
the head stays still and only the eyes move ("lizard"), classification accuracy
increases significantly from adding in eye pose. We characterize how that
accuracy varies between people, gaze strategies, and gaze regions.Comment: Accepted for Publication in IET Computer Vision. arXiv admin note:
text overlap with arXiv:1507.0476
Stability of axial orbits in galactic potentials
We investigate the dynamics in a galactic potential with two reflection
symmetries. The phase-space structure of the real system is approximated with a
resonant detuned normal form constructed with the method based on the Lie
transform. Attention is focused on the stability properties of the axial
periodic orbits that play an important role in galactic models. Using energy
and ellipticity as parameters, we find analytical expressions of bifurcations
and compare them with numerical results available in the literature.Comment: 20 pages, accepted for publication on Celestial Mechanics and
Dynamical Astronom
Elliptical motions of stars in close binary systems
Motions of stars in close binary systems with a conservative mass exchange
are examined. It is shown that Paczynski-Huang model widely used now for
obtaining the semi-major axis variation of a relative stars orbit is incorrect,
because it brings about large mistakes. A new model suitable for elliptical
orbits of stars is proposed. Both of reactive and attractive forces between
stars and a substance of the flowing jet are taken into account. A possibility
of a mass exchange at presence of accretion disk is considere
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