626 research outputs found
Exploring Peracetic Acid and Acidic pH Tolerance of Antibiotic Resistant Non-typhoidal Salmonella and Enterococcus faecium from Diverse Epidemiological and Genetic Backgrounds
Acid stress poses a common challenge for bacteria in diverse environments by the presence of inorganic (e.g., mammals stomach) or organic acids (e.g., feed additives; acid-based disinfectants). Limited knowledge exists regarding acid-tolerant strains of specific serotypes, clonal lineages, or sources in human/animal pathogens, namely non-typhoidal Salmonella enterica (NTS) and Enterococcus faecium (Efm). This study evaluated acidic pH and peracetic acid (PAA) susceptibility of Efm (n=72) and NTS (n=60) from diverse epidemiological/genetic backgrounds, and with multiple antibiotic resistance profiles. Efm minimum growth/survival-pH was 4,5-5/3-4 and for NTS 4,0-4,5/3,5-4,0. Among Efm, only those of clade-non-A1 (non-hospital associated) or food chain demonstrated greater tolerance to acidic pH compared to clade-A1 (hospital-associated clones) or clinical isolates (P<0.05). MDR (multidrug-resistant) NTS survived better to acidic pH (P<0.05). The MICPAA/MBCPAA was 70-120/80-150mg/L for Efm and 50-70/60-100mg/L for NTS. Efm-clade-A1 or MDR strains exhibited higher PAA tolerance than clade-non-A1 or non-MDR ones (P<0.05). Higher tolerance was found in non-MDR and clinical NTS than in food chain isolates (P<0.05), but not between different serogroups. This unique study identifies specific NTS or Efm populations more tolerant to acidic pH or PAA, emphasizing the need for further research to tailor control measures of public health and food safety within a One Health framework.</jats:p
Identification of a conserved operon in chlorhexidine tolerant Enterococcus faecium from different clades and origins
Uncovering the effects of copper feed supplementation on the selection of copper-tolerant and antibiotic-resistant Enterococcus in poultry production for sustainable environmental practices
Identification of 2CS-CHXT operon signature of chlorhexidine tolerance among Enterococcus faecium
Widespread of ampicillin-multidrug-resistant Enterococcus faecium in raw chicken meat, Portugal
High rates of ampicillin-multidrug-resistant Enterococcus faecium in chicken meat from Portugal
Sargassum muticum and Osmundea pinnatifida food-grade extracts with antioxidant activity for novel functional foods
Object-oriented Programming Laws for Annotated Java Programs
Object-oriented programming laws have been proposed in the context of
languages that are not combined with a behavioral interface specification
language (BISL). The strong dependence between source-code and interface
specifications may cause a number of difficulties when transforming programs.
In this paper we introduce a set of programming laws for object-oriented
languages like Java combined with the Java Modeling Language (JML). The set of
laws deals with object-oriented features taking into account their
specifications. Some laws deal only with features of the specification
language. These laws constitute a set of small transformations for the
development of more elaborate ones like refactorings
Combate intensivo aos triatomíneos de hábitos domiciliários. Resultados obtidos em área restrita (Cássia dos Coqueiros, Município de Cajuru) do Estado de São Paulo, Brasil
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