454 research outputs found

    Journal of African Christian Biography: v. 2, no. 4

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    A publication of the Dictionary of African Christian Biography with U.S. offices located at the Center for Global Christianity and Mission at Boston University. This issue focuses on: 1. The Martyrdom of Bernard Mizeki. 2. Bernard Mizeki. 3. Manche Masemola and Albert Luthuli: Iconic Figures of South African Christianity. 4. Manche Masemola. 5. Albert John Mvumbi Luthuli. 6. Multi-Talented Peacebuilder: Ambassador Dr. Bethuel A. Kiplagat. 7. Recent Print and Digital Resources Related to Christianity in Afric

    Air Traffic Simulation Technology for High-Population Metroplexes

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    IAI's MetroSim optimizes air traffic by simulating departures, arrivals, and activity in air and onthe ground in busy metroplexes, where flights impact each other at a single airport and among traffic at nearby airports. MetroSim evolved out of several NASA SBIR/STTR Awards and has since been used by NASA for flight simulation analysis. MetroSim has also been integrated with FAA and DOT technology, has produced studies for the Port Authority of New York and New Jersey, and is under development to support the Nav

    Archiva: Volume 4, Issue 2

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    https://digitalcommons.imsa.edu/archiva/1001/thumbnail.jp

    Cumulus: NASA Archives in the Cloud

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    How does iron interact with sporopollenin exine capsules? An X-ray absorption study including microfocus XANES and XRF imaging

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    Sporopollenin exine capsules (SECs) derived from plant spores and pollen grains have been proposed as adsorption, remediation and drug delivery agents. Despite many studies there is scant structural data available. This X-ray absorption investigation represents the first direct structural data on the interaction of metals with SECs and allows elucidation of their structure–property relationships. Fe K-edge XANES and EXAFS data have shown that the iron local environment in SECs (derived from Lycopodium clavatum) reacted with aqueous ferric chloride solutions is similar to that of ferrihydrite (FeOOH) and by implication ferritin. Fe Kα XRF micro-focus experiments show that there is a poor correlation between the iron distribution and the underlying SEC structure indicating that the SEC is coated in the FeOOH material. In contrast, the Fe Kα XRF micro-focus experiments on SECs reacted with aqueous ferrous chloride solutions show that there is a very high correlation between the iron distribution and the SEC structure, indicating a much more specific form of interaction of the iron with the SEC surface functional groups. Fe K-edge XANES and EXAFS data show that the FeII can be easily oxidised to give a structure similar to, but not identical to that in the FeIII case, and that even if anaerobic conditions are used there is still partial oxidation to FeIII

    Early marine survival of steelhead smolts in Puget Sound

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    Smolt-to adult survival rates for Puget Sound steelhead populations have declined substantially over the last 25 years and remain at or near historic lows. From 2006-2009, nearly 1,400 steelhead smolts from 9 watersheds within Puget Sound were tracked from river mouth to the Pacific Ocean using acoustic telemetry to: (1) estimate early marine survival through Puget Sound, (2) identify common areas of abnormally high mortality along the migration route, and (3) to identify factors that may influence survival. Cormac-Jolly-Seber mark-recapture models were used to jointly estimate survival and detection rate at telemetry arrays. Estimated survival rates from river mouths to near the Pacific Ocean ranged from 1.5% (Skokomish River hatchery smolts in 2009) to 34.0% (Big Beef Creek wild smolts in 2006), and averaged 14.9% for all populations. Factors influencing survival included population, migration segment, migration year, and rearing type (i.e., hatchery or wild), while geographic region, body length, and tag type (i.e., 7mm or 9mm) showed lesser effects. Comparison of survival rates between migration segments implicated central Puget Sound and Admiralty Inlet as potential areas of heightened mortality. Early marine survival rates estimated here are very low considering that steelhead smolts spend only about two to three weeks in Puget Sound before entering the Pacific Ocean. Mortality in Puget Sound may be a major driver behind low observed smolt-to adult survival rates. This study addresses a major gap in steelhead marine life history knowledge and can help to inform future Puget Sound steelhead recovery planning efforts

    Meta-Mass Shift Chemical (MeMSChem) profiling of metabolomes from coral reefs

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    Untargeted metabolomics of environmental samples routinely detects thousands of small molecules, the vast majority of which cannot be identified. Meta-mass shift chemical (MeMSChem) profiling was developed to identify mass differences between related molecules using molecular networks. This approach illuminates metabolome-wide relationships between molecules and the putative chemical groups that differentiate them (e.g., H2, CH2, COCH2). MeMSChem profiling was used to analyze a publicly available metabolomic dataset of coral, algal, and fungal mat holobionts (i.e., the host and its associated microbes and viruses) sampled from some of Earth's most remote and pristine coral reefs. Each type of holobiont had distinct mass shift profiles, even when the analysis was restricted to molecules found in all samples. This result suggests that holobionts modify the same molecules in different ways and offers insights into the generation of molecular diversity. Three genera of stony corals had distinct patterns of molecular relatedness despite their high degree of taxonomic relatedness. MeMSChem profiles also partially differentiated between individuals, suggesting that every coral reef holobiont is a potential source of novel chemical diversity

    Reduced neutrophil granular proteins and post-treatment modulation in tuberculous lymphadenitis

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    BACKGROUND: Neutrophils are important for host innate immune defense and mediate inflammatory responses. Pulmonary tuberculosis (PTB) is associated with increased neutrophil granular protein (NGP) levels in the circulation. However, the systemic levels of neutrophil granular proteins were not examined in tuberculous lymphadenitis (TBL) disease. METHODS: We measured the systemic levels of NGP (myeloperoxidase [MPO], elastase and proteinase 3 [PRTN3]) in TBL and compared them to latent tuberculosis (LTB) and healthy control (HC) individuals. We also measured the pre-treatment (Pre-T) and post-treatment (Post-T) systemic levels of neutrophil granular proteins in TBL individuals upon anti-tuberculosis treatment (ATT) completion. In addition, we studied the correlation and discriminatory ability of NGPs using receiver operating characteristic (ROC) analysis. RESULTS: Our data suggests that systemic levels of NGPs (MPO, PRTN3, elastase) were significantly reduced in TBL individuals compared to LTB and HC individuals. Similarly, after ATT, the plasma levels of MPO and elastase but not PRTN3 were significantly elevated compared to pre-treatment levels. NGPs (except PRTN3) were positively correlated with absolute neutrophil count of TBL, LTB and HC individuals. Further, NGPs were able to significantly discriminate TBL from LTB and HC individuals. CONCLUSION: Hence, we conclude reduced neutrophil granular protein levels might be associated with disease pathogenesis in TBL
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