The Metallicity of Pre-Galactic Globular Clusters: Observational consequences of the first stars

We explore a scenario where metal-poor globular clusters (GCs) are enriched by the first supernovae in the Universe. If the first stars in a 10^7 Msun dark halo were very massive (>180 Msun), then a pair instability supernova from a single massive star can produce sufficient iron to enrich 10^6 Msun of pristine, primordial gas to [Fe/H] ~ -2. In such a scenario, where a single massive star acts as a seed for halo GCs, the accurate abundance analysis of GC stars would allow a direct measurement of the Population III initial mass. Using the latest theoretical yields for zero metallicity stars in the mass range 140-260 Msun, we find that the metals expelled from a ~230 Msun star are consistent with [Si/Fe] and [Ca/Fe] observed in GC stars. However, no single star in this mass range can simultaneously explain all halo GC heavy-element abundance ratios, such as [V/Fe], [Ti/Fe] and [Ni/Fe]. These require a combination masses for the Population III stellar progenitors. The various observational consequences of this scenario are discussed.Comment: 5 pages, 2 figures, accepted for publication in ApJ Lette

Building Classroom and Organizational Structure Around Positive Cultural Values

The Compass Project is a self-formed group of graduate and undergraduate students in the physical sciences at UC Berkeley. Our goals are to improve undergraduate physics education, provide opportunities for professional development, and increase retention of students-especially those from populations typically underrepresented in the physical sciences. Compass fosters a diverse, collaborative student community by providing a wide range of services, including a summer program and fall/spring seminar courses. We describe Compass's cultural values, discuss how community members are introduced to and help shape those values, and demonstrate how a single set of values informs the structure of both our classroom and organization.We emphasize that all members of the Compass community participate in, and benefit from, our cultural values, regardless of status as student, teacher, or otherwise.Comment: 4 pages, to be submitted to PERC 2012 proceeding

A Comprehensive Radio and Optical Study of Abell 2256: Activity from an Infalling Group

Abell 2256 is a nearby (z~0.06), rich cluster of galaxies with fascinating observed properties across a range of wavelengths. Long believed to represent a cluster merger, recent X-ray and optical results have suggested that in addition to the primary cluster and subcluster there is evidence for a third, poorer system. We present wide-field, high sensitivity 1.4 GHz VLA radio observations of Abell 2256 in conjunction with optical imaging and additional spectroscopy. Over 40 cluster radio galaxies are identified, with optical spectroscopy indicating the emission source (star formation or AGN) for most of them. While the overall fraction of galaxies exhibiting radio emission is consistent with a large sample of other nearby clusters, we find an increase in the activity level of galaxies belonging to the third system (hereafter, the ``Group''). Specifically, the Group has relatively more star formation than both the primary cluster and main subcluster. The position of the Group is also coincident with the observed cluster radio relic. We suggest that the Group recently (~0.3 Gyr) merged with the primary cluster and that this merger, not the ongoing merger of the primary and the main subcluster, might be responsible for many of the unusual radio properties of Abell 2256. Furthermore, the greater star formation activity of the Group suggests that the infall of groups is an important driver of galaxy evolution in clusters.Comment: 21 pages plus 13 JPEG figures; to appear in the Astronomical Journa

The X-ray Luminosity Function of Nearby Rich and Poor Clusters of Galaxies: A Cosmological Probe

In this letter, we present a new determination of the local (z<0.09) X-ray luminosity function (XLF) using a large, statistical sample of 294 Abell clusters and the ROSAT All-Sky-Survey. Given our large sample size, we have reduced errors by a factor of two for L(X)(0.5-2keV)>10^43 ergs/sec. We combine our data with previous work in order to explore possible constraints imposed by the shape of the XLF on cosmological models. A set of currently viable cosmologies is used to construct theoretical XLFs assuming Lx is proportional to M^p and a sigma_8-Omega_0 constraint (from Viana & Liddle 1996) based on the local X-ray temperature function. We fit these models to our observed XLF and verify that the simplest adiabatic, analytic scaling relation (e.g. Kaiser 1986) disagrees strongly with observations. If we assume that clusters can be described by the pre-heated, constant core-entropy models of Evrard & Henry (1991) then the observed XLF is consistent only with 0.1 < Omega_0 < 0.4 if the energy per unit mass in galaxies is roughly equal to the gas energy (ie if beta=1). (abridged)Comment: 4 pages, 2 figures, accepted for publication in ApJ Letters. uses emulateapj.st

A dynamical model for correlated two-pion-exchange in the pion-nucleon interaction

A microscopic model for the $N\bar N\to\pi\pi$ process is presented in the meson exchange framework, which in the pseudophysical region agrees with available quasiempirical information. The scalar ($\sigma$) and vector ($\rho$) piece of correlated two--pion exchange in the pion--nucleon interaction is then derived via dispersion integrals over the unitarity cut. Inherent ambiguities in the method and implications for the description of pion--nucleon scattering data are discussed.Comment: 20 pages, 11 postscript figure

Moments of the Virtual Photon Structure Function

The photon structure function is a useful testing ground for QCD. It is perturbatively computable apart from a contribution from what is usually called the hadronic component of the photon. There have been many proposals for this nonperturbative part of the real photon structure function. By studying moments of the virtual photon structure function, we explore the extent to which these proposed nonperturbative contributions can be identified experimentally.Comment: LaTeX, 16 pages + 14 compressed and uuencoded postscript figures, UMN-TH-1111/9

Simple models of the chemical field around swimming plankton

Background. Cervical cancer is the fourth most common cancer in women, and we recently reported human leukocyte antigen (HLA) alleles showing strong associations with cervical neoplasia risk and protection. HLA ligands are recognized by killer immunoglobulin-like receptors (KIRs) expressed on a range of immune cell subsets, governing their proinflammatory activity. We hypothesized that the inheritance of particular HLA-KIR combinations would increase cervical neoplasia risk. Methods. Here, we used HLA and KIR dosages imputed from single-nucleotide polymorphism genotype data from 2143 cervical neoplasia cases and 13 858 healthy controls of European decent. Results. The following 4 novel HLA alleles were identified in association with cervical neoplasia, owing to their linkage disequilibrium with known cervical neoplasia-associated HLA-DRB1 alleles: HLA-DRB3*9901 (odds ratio [OR], 1.24; P = 2.49 × 10−9), HLA-DRB5*0101 (OR, 1.29; P = 2.26 × 10−8), HLA-DRB5*9901 (OR, 0.77; P = 1.90 × 10−9), and HLA-DRB3*0301 (OR, 0.63; P = 4.06 × 10−5). We also found that homozygosity of HLA-C1 group alleles is a protective factor for human papillomavirus type 16 (HPV16)-related cervical neoplasia (C1/C1; OR, 0.79; P = .005). This protective association was restricted to carriers of either KIR2DL2 (OR, 0.67; P = .00045) or KIR2DS2 (OR, 0.69; P = .0006). Conclusions. Our findings suggest that HLA-C1 group alleles play a role in protecting against HPV16-related cervical neoplasia, mainly through a KIR-mediated mechanism

Microprojection arrays applied to skin generate mechanical stress, induce an inflammatory transcriptome and cell death, and improve vaccine-induced immune responses

Abstract: Chemical adjuvants are typically used to improve immune responses induced by immunisation with protein antigens. Here we demonstrate an approach to enhance immune responses that does not require chemical adjuvants. We applied microprojection arrays to the skin, producing a range of controlled mechanical energy to invoke localised inflammation, while administering influenza split virus protein antigen. We used validated computational modelling methods to identify links between mechanical stress and energy generated within the skin strata and resultant cell death. We compared induced immune responses to those induced by needle-based intradermal antigen delivery and used a systems biology approach to examine the nature of the induced inflammatory response, and correlated this with markers of cell stress and death. Increasing the microprojection array application energy and the addition of QS-21 adjuvant were each associated with enhanced antibody response to delivered antigen and with induction of gene transcriptions associated with TNF and NF-κB signalling pathways. We concluded that microprojection intradermal antigen delivery inducing controlled local cell death could potentially replace chemical adjuvants to enhance the immune response to protein antigen

Does shade improve light interception efficiency? A comparison among seedlings from shade-tolerant and -intolerant temperate deciduous tree species

• Here, we tested two hypotheses: shading increases light interception efficiency (LIE) of broadleaved tree seedlings, and shade-tolerant species exhibit larger LIEs than do shade-intolerant ones. The impact of seedling size was taken into account to detect potential size-independent effects on LIE. LIE was defined as the ratio of mean light intercepted by leaves to light intercepted by a horizontal surface of equal area. • Seedlings from five species differing in shade tolerance (Acer saccharum, Betula alleghaniensis, A. pseudoplatanus, B. pendula, Fagus sylvatica) were grown under neutral shading nets providing 36, 16 and 4% of external irradiance. Seedlings (1- and 2-year-old) were three-dimensionally digitized, allowing calculation of LIE. • Shading induced dramatic reduction in total leaf area, which was lowest in shade-tolerant species in all irradiance regimes. Irradiance reduced LIE through increasing leaf overlap with increasing leaf area. There was very little evidence of significant size-independent plasticity of LIE. • No relationship was found between the known shade tolerance of species and LIE at equivalent size and irradiance