187 research outputs found

    Frequency Locking for Combustion Synthesis in Periodic Medium

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    Solutions of a 1-D free-interface problem modeling solid combustion front propagating in combustible mixture with periodically varying concentration of reactant exhibit classical phenomenon of mode locking. Numerical simulation shows a variety of locked periodic, quasi-periodic and chaotic solutions.Comment: 11 pages, 6 figure

    The Business Cycle Peak of March 2001

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    A Mammalian Conserved Element Derived from SINE Displays Enhancer Properties Recapitulating Satb2 Expression in Early-Born Callosal Projection Neurons

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    Short interspersed repetitive elements (SINEs) are highly repeated sequences that account for a significant proportion of many eukaryotic genomes and are usually considered “junk DNA”. However, we previously discovered that many AmnSINE1 loci are evolutionarily conserved across mammalian genomes, suggesting that they may have acquired significant functions involved in controlling mammalian-specific traits. Notably, we identified the AS021 SINE locus, located 390 kbp upstream of Satb2. Using transgenic mice, we showed that this SINE displays specific enhancer activity in the developing cerebral cortex. The transcription factor Satb2 is expressed by cortical neurons extending axons through the corpus callosum and is a determinant of callosal versus subcortical projection. Mouse mutants reveal a crucial function for Sabt2 in corpus callosum formation. In this study, we compared the enhancer activity of the AS021 locus with Satb2 expression during telencephalic development in the mouse. First, we showed that the AS021 enhancer is specifically activated in early-born Satb2+ neurons. Second, we demonstrated that the activity of the AS021 enhancer recapitulates the expression of Satb2 at later embryonic and postnatal stages in deep-layer but not superficial-layer neurons, suggesting the possibility that the expression of Satb2 in these two subpopulations of cortical neurons is under genetically distinct transcriptional control. Third, we showed that the AS021 enhancer is activated in neurons projecting through the corpus callosum, as described for Satb2+ neurons. Notably, AS021 drives specific expression in axons crossing through the ventral (TAG1−/NPY+) portion of the corpus callosum, confirming that it is active in a subpopulation of callosal neurons. These data suggest that exaptation of the AS021 SINE locus might be involved in enhancement of Satb2 expression, leading to the establishment of interhemispheric communication via the corpus callosum, a eutherian-specific brain structure

    Interactions Between Climate and Trade Policies: A Survey

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    Media use, anti-Americanism and international support for the Iraq War

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    This study investigates the impact of pre-war news coverage on international support for President Bush's decision to invade Iraq in 2003. The study is based on a survey conducted one week prior to the start of the Iraq War among 1787 university students from six countries in Europe, Asia and the Middle East. The findings indicate that exposure to pre-war news coverage was associated with more positive attitudes toward Iraq and higher levels of fear related to the possible consequences of a war. Stronger international support for a US invasion correlated with more positive attitudes toward Iraq, less fear about a possible war and lower levels of anti-Americanism. Copyright © 2006 Sage Publications

    The Stability of the Adjusted and Unadjusted Environmental Kuznets Curve

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