ISO SWS Observations of H II Regions in NGC 6822 and I ZW 36: Sulfur Abundances and Temperature Fluctuations

We report ISO SWS infrared spectroscopy of the H II region Hubble V in NGC 6822 and the blue compact dwarf galaxy I Zw 36. Observations of Br alpha, [S III] at 18.7 and 33.5 microns, and [S IV] at 10.5 microns are used to determine ionic sulfur abundances in these H II regions. There is relatively good agreement between our observations and predictions of S^+3 abundances based on photoionization calculations, although there is an offset in the sense that the models overpredict the S^+3 abundances. We emphasize a need for more observations of this type in order to place nebular sulfur abundance determinations on firmer ground. The S/O ratios derived using the ISO observations in combination with optical data are consistent with values of S/O, derived from optical measurements of other metal-poor galaxies. We present a new formalism for the simultaneous determination of the temperature, temperature fluctuations, and abundances in a nebula, given a mix of optical and infrared observed line ratios. The uncertainties in our ISO measurements and the lack of observations of [S III] lambda 9532 or lambda 9069 do not allow an accurate determination of the amplitude of temperature fluctuations for Hubble V and I Zw 36. Finally, using synthetic data, we illustrate the diagnostic power and limitations of our new method.Comment: 32 Pages total, including 6 encapsulated postscript figures (one with two parts). Accepted for Publication in the 20 Dec 2002 Ap

On the Metallicity of Star-forming Dwarf Galaxies

We construct three extreme different scenarios of the star formation histories applicable to a sample of dwarf galaxies, based either on their present metallicity or their luminosity. The three possible scenarios imply different mechanical energy input rates and these we compare with the theoretical lower limits established for the ejection of processed matter out of dwarf galaxies. The comparison strongly points at the existence of extended gaseous haloes in these galaxies, acting as the barrier that allows galaxies to retain their metals and enhance their abundance. At the same time our findings strongly point at a continuous star-forming process, rather than to coeval bursts, as the main contributors to the overall metallicity in our galaxy sample.Comment: 8 pages, 3 figures, 2 table, Accepted for publication in Ap

The Changing Landscape for Stroke\ua0Prevention in AF: Findings From the GLORIA-AF Registry Phase 2

Background GLORIA-AF (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation) is a prospective, global registry program describing antithrombotic treatment patterns in patients with newly diagnosed nonvalvular atrial fibrillation at risk of stroke. Phase 2 began when dabigatran, the first non\u2013vitamin K antagonist oral anticoagulant (NOAC), became available. Objectives This study sought to describe phase 2 baseline data and compare these with the pre-NOAC era collected during phase 1. Methods During phase 2, 15,641 consenting patients were enrolled (November 2011 to December 2014); 15,092 were eligible. This pre-specified cross-sectional analysis describes eligible patients\u2019 baseline characteristics. Atrial fibrillation disease characteristics, medical outcomes, and concomitant diseases and medications were collected. Data were analyzed using descriptive statistics. Results Of the total patients, 45.5% were female; median age was 71 (interquartile range: 64, 78) years. Patients were from Europe (47.1%), North America (22.5%), Asia (20.3%), Latin America (6.0%), and the Middle East/Africa (4.0%). Most had high stroke risk (CHA2DS2-VASc [Congestive heart failure, Hypertension, Age  6575 years, Diabetes mellitus, previous Stroke, Vascular disease, Age 65 to 74 years, Sex category] score  652; 86.1%); 13.9% had moderate risk (CHA2DS2-VASc = 1). Overall, 79.9% received oral anticoagulants, of whom 47.6% received NOAC and 32.3% vitamin K antagonists (VKA); 12.1% received antiplatelet agents; 7.8% received no antithrombotic treatment. For comparison, the proportion of phase 1 patients (of N = 1,063 all eligible) prescribed VKA was 32.8%, acetylsalicylic acid 41.7%, and no therapy 20.2%. In Europe in phase 2, treatment with NOAC was more common than VKA (52.3% and 37.8%, respectively); 6.0% of patients received antiplatelet treatment; and 3.8% received no antithrombotic treatment. In North America, 52.1%, 26.2%, and 14.0% of patients received NOAC, VKA, and antiplatelet drugs, respectively; 7.5% received no antithrombotic treatment. NOAC use was less common in Asia (27.7%), where 27.5% of patients received VKA, 25.0% antiplatelet drugs, and 19.8% no antithrombotic treatment. Conclusions The baseline data from GLORIA-AF phase 2 demonstrate that in newly diagnosed nonvalvular atrial fibrillation patients, NOAC have been highly adopted into practice, becoming more frequently prescribed than VKA in Europe and North America. Worldwide, however, a large proportion of patients remain undertreated, particularly in Asia and North America. (Global Registry on Long-Term Oral Antithrombotic Treatment in Patients With Atrial Fibrillation [GLORIA-AF]; NCT01468701

Quelques instabilites elastiques locales dans les cholesteriques

SIGLECNRS T Bordereau / INIST-CNRS - Institut de l'Information Scientifique et TechniqueFRFranc

Subdiffusion and dynamical heterogeneities in a lattice glass model

4 pages, 4 figuresInternational audienceWe study a kinetically constrained lattice glass model in which continuous local densities are randomly redistributed on neighbouring sites with a kinetic constraint that inhibits the process at high densities, and a random bias accounting for attractive or repulsive interactions. The full steady-state distribution can be computed exactly in any space dimension d. Dynamical heterogeneities are characterized by a length scale that diverges when approaching the critical density. The glassy dynamics of the model can be described as a reaction-diffusion process for the mobile regions. The motion of mobile regions is found to be subdiffusive, for a large range of parameters, due to a self-induced trapping mechanism