546 research outputs found
Online VNF Scaling in Datacenters
Network Function Virtualization (NFV) is a promising technology that promises
to significantly reduce the operational costs of network services by deploying
virtualized network functions (VNFs) to commodity servers in place of dedicated
hardware middleboxes. The VNFs are typically running on virtual machine
instances in a cloud infrastructure, where the virtualization technology
enables dynamic provisioning of VNF instances, to process the fluctuating
traffic that needs to go through the network functions in a network service. In
this paper, we target dynamic provisioning of enterprise network services -
expressed as one or multiple service chains - in cloud datacenters, and design
efficient online algorithms without requiring any information on future traffic
rates. The key is to decide the number of instances of each VNF type to
provision at each time, taking into consideration the server resource
capacities and traffic rates between adjacent VNFs in a service chain. In the
case of a single service chain, we discover an elegant structure of the problem
and design an efficient randomized algorithm achieving a e/(e-1) competitive
ratio. For multiple concurrent service chains, an online heuristic algorithm is
proposed, which is O(1)-competitive. We demonstrate the effectiveness of our
algorithms using solid theoretical analysis and trace-driven simulations.Comment: 9 pages, 4 figure
MOEMS deformable mirror testing in cryo for future optical instrumentation
MOEMS Deformable Mirrors (DM) are key components for next generation
instruments with innovative adaptive optics systems, in existing telescopes and
in the future ELTs. These DMs must perform at room temperature as well as in
cryogenic and vacuum environment. Ideally, the MOEMS-DMs must be designed to
operate in such environment. We present some major rules for designing /
operating DMs in cryo and vacuum. We chose to use interferometry for the full
characterization of these devices, including surface quality measurement in
static and dynamical modes, at ambient and in vacuum/cryo. Thanks to our
previous set-up developments, we placed a compact cryo-vacuum chamber designed
for reaching 10-6 mbar and 160K, in front of our custom Michelson
interferometer, able to measure performances of the DM at actuator/segment
level as well as whole mirror level, with a lateral resolution of 2{\mu}m and a
sub-nanometric z-resolution. Using this interferometric bench, we tested the
Iris AO PTT111 DM: this unique and robust design uses an array of single
crystalline silicon hexagonal mirrors with a pitch of 606{\mu}m, able to move
in tip, tilt and piston with strokes from 5 to 7{\mu}m, and tilt angle in the
range of +/-5mrad. They exhibit typically an open-loop flat surface figure as
good as <20nm rms. A specific mount including electronic and opto-mechanical
interfaces has been designed for fitting in the test chamber. Segment
deformation, mirror shaping, open-loop operation are tested at room and cryo
temperature and results are compared. The device could be operated successfully
at 160K. An additional, mainly focus-like, 500 nm deformation is measured at
160K; we were able to recover the best flat in cryo by correcting the focus and
local tip-tilts on some segments. Tests on DM with different mirror thicknesses
(25{\mu}m and 50{\mu}m) and different coatings (silver and gold) are currently
under way.Comment: 11 pages, 12 Figure
Fluid Power Vehicle Challenge - The Incompressibles - Final Design Report
This report provides a comprehensive description of the research, analysis and design work that The Incompressibles have completed thus far in the senior project process. This document includes all the work that The Incompressibles have completed for the team’s Preliminary Design Review (PDR), Critical Design Review (CDR), the work leading up to the 2019 FPVC competiton and the competition results. This report includes the initial research that the team completed for the fluid power competition, first iterations of designs, final iterations of designs, manufacturing results and processes, and finally testing and results from competition. With a new design for the bike frame, drivetrain, mechatronics, power decoupling and hydraulics, The Incompressibles dramatically changed Cal Poly’s fluid power bike platform in the Fluid Power Vehicle Challenge. This bike was built with the direct intention of getting first place at this year’s fluid powered bike challenge competition
Santo-Pietro-di-Tenda – Monte Revincu
Le complexe mégalithique du Monte Revincu a été signalé par A. de Mortillet dès 1893, mais son étude n’avait pas été réactualisée. L’ensemble est situé à l’ouest du golfe de Saint-Florent. La densité et la diversité des monuments dans cette microrégion, à la limite du Nebbio et des Agriate permet une bonne approche de l’ensemble des questions d’analyse spatiale. L’occupation préhistorique de la région est essentiellement constituée par des sépultures mégalithiques et des statues-menhirs. Les ..
Santo-Pietro-di-Tenda – Monte Revincu
Le complexe mégalithique du Monte Revincu a été signalé par A. de Mortillet dès 1893, mais son étude n’avait pas été réactualisée. L’ensemble est situé à l’ouest du golfe de Saint-Florent. La densité et la diversité des monuments dans cette microrégion, à la limite du Nebbio et des Agriate permet une bonne approche de l’ensemble des questions d’analyse spatiale. L’occupation préhistorique de la région est essentiellement constituée par des sépultures mégalithiques et des statues-menhirs. Les ..
Corte – Citadelle
Le choix des zones retenues pour les opérations de terrain a été déterminé dans un premier temps par la stricte emprise au sol des bâtiments du futur musée de la Corse. Elles couvraient la totalité du bastion VII, la partie orientale du bastion I et les terrasses jouxtant la caserne Serrurier à l’ouest. Une décision modificative survenue en cours d’intervention a eu pour effet d’élargir les travaux de terrassement à une grande partie du bastion I entraînant de ce fait une extension des fouill..
Children Attending Day Care Centers are a Year-round Reservoir of Gastrointestinal Viruses
Abstract Viral gastroenteritis causes high morbidity worldwide. In this study, stool samples from 179 children aged 0–6 years attending Danish day care centers were investigated for gastrointestinal viruses. Each child was observed for one year with submission of samples and questionnaires every two months. Adenovirus, norovirus, rotavirus, and sapovirus were detected in samples using real-time PCR. A total of 229 (33%) of the 688 samples collected tested positive for at least one virus. At the first sampling point, adenovirus was shed by 6%, norovirus genotype I by 3% and genotype II by 12%, rotavirus A by 9%, and sapovirus by 21% of the 142 children included in the risk factor analyses. Increasing age was identified as a protective factor against testing positive for gastrointestinal virus, whereas nausea during the previous two months was positively associated with testing positive. Odds of shedding adenovirus were 9.6 times higher among children treated with antibiotics within the previous two months than among children who were not. Gastrointestinal viruses were shed year-round and high viral loads were observed in samples from both symptomatic and asymptomatic children, suggesting children in day care as a reservoir and a possible source of spreading of viruses into the community
Imprinting at the PLAGL1 domain is contained within a 70-kb CTCF/cohesin-mediated non-allelic chromatin loop
Paternal duplications of chromosome 6q24, a region that contains the imprinted PLAGL1 and HYMAI transcripts, are associated with transient neonatal diabetes mellitus. A common feature of imprinted genes is that they tend to cluster together, presumably as a result of sharing common cis-acting regulatory elements. To determine the extent of this imprinted cluster in human and mouse, we have undertaken a systematic analysis of allelic expression and DNA methylation of the genes mapping within an similar to 1.4-Mb region flanking PLAGL1/Plagl1. We confirm that all nine neighbouring genes are biallelically expressed in both species. In human we identify two novel paternally expressed PLAGL1 coding transcripts that originate from unique promoter regions. Chromatin immunoprecipitation for CTCF and the cohesin subunits RAD21 and SMC3 reveals evolutionarily conserved binding sites within unmethylated regions similar to 5 kb downstream of the PLAGL1 differentially methylated region and within the PLAGL1 3' untranslated region (UTR). Higher-order chromatin looping occurs between these regions in both expressing and non-expressing tissues, forming a non-allelic chromatin loop around the PLAGL1/Plagl1 gene. In placenta and brain tissues, we identify an additional interaction between the PLAGL1 P3/P4 promoters and the unmethylated element downstream of the PLAGL1 differentially methylated region that we propose facilitates imprinted expression of these alternative isoforms
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