Statistics of the fractional polarisation of compact radio sources in Planck maps

In this work we apply the stacking technique to estimate the average fractional polarisation from 30 to 353 GHz of a primary sample of 1560 compact sources - essentially all radio sources - detected in the 30 GHz Planck all-sky map and listed in the second version of the Planck Catalogue of Compact Sources (PCCS2). We divide our primary sample in two subsamples according to whether the sources lay (679 sources) or not (881 sources) inside the sky region defined by the Planck Galactic mask (fsky ~ 60 per cent) and the area around the Magellanic Clouds. We find that the average fractional polarisation of compact sources is approximately constant (with frequency) in both samples (with a weighted mean over all the channels of 3.08 per cent outside and 3.54 per cent inside the Planck mask). In the sky region outside the adopted mask, we also estimate the {\mu} and {\sigma} parameters for the log-normal distribution of the fractional polarisation, finding a weighted mean value over all the Planck frequency range of 1.0 for {\sigma} and 0.7 for {\mu} (that would imply a weighted mean value for the median fractional polarisation of 1.9 per cent).Comment: 12 pages, 7 figures, 2 tables, MNRAS in pres

The Effectiveness of Advanced Practice Nurses with Respect to Complex Chronic Wounds in the Management of Venous Ulcers

This study aims to evaluate the effectiveness of advanced practice nurses with respect to complex chronic wounds (APN-CCWs) in the care of patients with venous ulcers. A multicentric, quasi-experimental pre-post study was conducted without a control group in the sanitary management areas where the APN-CCW program is being piloted. The intervention consisted of a mass training of clinical nurses from the participating districts on the proper management of injuries and the use of compression therapy. The data were collected through a specifically constructed questionnaire with questions regarding descriptive variables of injuries and their treatment. A total of 643 professionals responded (response rate of 89.1%), attending to a total population of 707,814 inhabitants. An increase in multilayer bandage use by 15.67%, an increase in elastic bandage use by 13.24%, and a significant decrease in the referral of patients to consultation with hospital specialists was achieved, from 21.08% to 12.34%. The number of patients referred to the APNs was 13.25%, which implied a resolution rate of 94.08% of their injuries. In conclusion, the coordination by the APN-CCWs in patients with venous ulcers was effective in improving the continuity of care, in the optimization of resources, and in their care role

Estudio sobre las motivaciones para la práctica de la escalada en roca

El presente artículo estudia las razones que llevan a los escaladores en roca al aire libre a practicar este deporte, analizando las relaciones existentes entre estas motivaciones y el género. Para ello se empleó un cuestionario autoadministrado a una muestra de 146 escaladores (89 hombres y 57 mujeres) de 18 a 54 años de edad (media = 31,24 ± 6,96 años). Los resultados pusieron de manifiesto que las principales razones elegidas por los escaladores eran intrínsecas, destacando entre ellas el contacto con la naturaleza, la búsqueda de aventura, el reto personal y la diversión. Entre los motivos menos señalados encontramos la mejora de la imagen, la competición y el reconocimiento social. Por género, las escaladoras eligieron en mayor medida la diversión y la mejora de la imagen como motivos para escalar

Estudi sobre les motivacions per a la pràctica de l’escalada en roca

Aquest article estudia les raons que porten els escaladors en roca a l’aire lliure a practicar aquest esport, analitzant les relacions existents entre aquestes motivacions i el gènere. Per a això es va emprar un qüestionari autoadministrat en una mostra de 146 escaladors (89 homes i 57 dones) de 18 a 54 anys (mitjana = 31,24 ± 6,96 anys). Els resultats van posar de manifest que les principals raons elegides pels escaladors eren intrínseques, destacant entre aquestes el contacte amb la natura, la recerca d’aventura, el repte personal i la diversió. Entre els motius menys assenyalats hi trobem la millora de la imatge, la competició i el reconeixement social. Per gènere, les escaladores van elegir en major grau la diversió i la millora de la imatge com a motius per escalar

Celestial open strings at one-loop

We study celestial amplitudes in string theory at one-loop. Celestial amplitudes describe scattering processes of boost eigenstates and relate to amplitudes in the more standard basis of momentum eigenstates through a Mellin transform. They are thus sensitive to both the ultraviolet and the infrared, which raises the question of how to appropriately take the field theory limit of string amplitudes in the celestial basis. We address this problem in the context of four-dimensional genus-one scattering processes of gluons in open string theory which reach the two-dimensional celestial sphere at null infinity. We show that the Mellin transform commutes with the adequate limit in the worldsheet moduli space and reproduces the celestial one-loop field theory amplitude expressed in the worldline formalism. The dependence on $\alpha'$ continues to be a simple overall factor in one-loop celestial amplitudes albeit with a power that is shifted by three units with respect to tree-level, thus making manifest that the dimensionless parameter $g_{10}^2/\alpha'^3$ organizes the loop expansion in the celestial basis.Comment: 23 pages, 1 figur

The Pursuit of External Knowledge in Eco-Innovation. Analysis of the Agri-Food Sector in Spain

The research about the search for opportunities through open cooperation strategies points to an exchange of knowledge among a certain number of sources, aimed at sustaining competitive advantage. From this new vision emerges the paradigm of open innovation, which has prompted a change in the organization of resources, information filtering, and rapid absorptive capacity. Awareness of climate problems and external societal pressures can motivate companies to create new technologies and new forms of cooperation to avoid environmental problems. Based on a survey of Spanish agri-food firms, we find that the depth of external sources of innovation increases environmental improvement in a U-shaped relationship

Changes in expression of hypothalamic releasing hormone receptors in individual rat anterior pituitary cells during maturation, puberty and senescence

Producción CientíficaAnterior pituitary (AP) is formed by five different cell types, each one producing a different AP hormone whose secretion is regulated by a specific hypothalamic-releasing hormone (HRH). On the other hand, a significant number of AP cells express multiple HRH receptors (multiresponsive cells). Plastic changes in expression of HRH receptors in individual AP cells are involved in critical endocrine events. Here we have characterized the changes in functional responses to CRH, LHRH, TRH, and GHRH in individual AP cells throughout the whole life span of the rat. To this end, calcium responses to the HRHs were followed by single-cell imaging in freshly dispersed AP cells prepared from rats of different ages (0–540 postnatal days). Three different cell pools were identified: 1) monoresponsive cells, holding a single class of HRH receptor; 2) multiresponsive cells; and 3) nonresponsive cells. The relative abundance of each pool changed with age. Nonresponsive cells were abundant at birth, multiresponsive cells were abundant at puberty, and monoresponsive cells dominated at senescence. The relative abundance of each HRH receptor changed largely with age but not gender. In addition, the contribution of monoresponsive and multiresponsive cells to responses to each HRH changed very much with age. Thus, the anterior pituitary shows large changes in cell populations typed by functional responses to HRHs during maturation, puberty, and senescence.Fondo de Investigaciones Sanitarias (grant FIS 03/1231)Ministerio de Ciencia, Innovación y Universidades (grants BFI 2001-2073 and BFU-2004-02765/BFI

Using the Social-Local-Mobile App for Smoking Cessation in the SmokeFreeBrain Project: Protocol for a Randomized Controlled Trial

Background: Smoking is considered the main cause of preventable illness and early deaths worldwide. The treatment usually prescribed to people who wish to quit smoking is a multidisciplinary intervention, combining both psychological advice and pharmacological therapy, since the application of both strategies significantly increases the chance of success in a quit attempt. Objective: We present a study protocol of a 12-month randomized open-label parallel-group trial whose primary objective is to analyze the efficacy and efficiency of usual psychopharmacological therapy plus the Social-Local-Mobile app (intervention group) applied to the smoking cessation process compared with usual psychopharmacological therapy alone (control group). Methods: The target population consists of adult smokers (both male and female) attending the Smoking Cessation Unit at Virgen del Rocío University Hospital, Seville, Spain. Social-Local-Mobile is an innovative intervention based on mobile technologies and their capacity to trigger behavioral changes. The app is a complement to pharmacological therapies to quit smoking by providing personalized motivational messages, physical activity monitoring, lifestyle advice, and distractions (minigames) to help overcome cravings. Usual pharmacological therapy consists of bupropion (Zyntabac 150 mg) or varenicline (Champix 0.5 mg or 1 mg). The main outcomes will be (1) the smoking abstinence rate at 1 year measured by means of exhaled carbon monoxide and urinary cotinine tests, and (2) the result of the cost-effectiveness analysis, which will be expressed in terms of an incremental cost-effectiveness ratio. Secondary outcome measures will be (1) analysis of the safety of pharmacological therapy, (2) analysis of the health-related quality of life of patients, and (3) monitoring of healthy lifestyle and physical exercise habits. Results: Of 548 patients identified using the hospital’s electronic records system, we excluded 308 patients: 188 declined to participate and 120 did not meet the inclusion criteria. A total of 240 patients were enrolled: the control group (n=120) will receive usual psychopharmacological therapy, while the intervention group (n=120) will receive usual psychopharmacological therapy plus the So-Lo-Mo app. The project was approved for funding in June 2015. Enrollment started in October 2016 and was completed in October 2017. Data gathering was completed in November 2018, and data analysis is under way. The first results are expected to be submitted for publication in early 2019. Conclusions: Social networks and mobile technologies influence our daily lives and, therefore, may influence our smoking habits as well. As part of the SmokeFreeBrain H2020 European Commission project, this study aims at elucidating the potential role of these technologies when used as an extra aid to quit smoking

Turning carbon dots into selenium bearing nanoplatforms with in vitro GPx-like activity and pro-oxidant activity

Selenium (Se) has been defined as the “Janus element”, with one face showing antioxidant activity and the other pro-oxidant activity. The biological effect of Se depends on both dose and speciation. Se nanoparticles are attracting major interest, although their large-scale preparation for biomedical applications is not trivial. We hypothesize that acid anhydride-coated carbon dots (AACD) are an attractive platform for preparing nanoparticles containing chemically defined Se. The reaction of AA-CD with 3- selenocyanatopropan-1-amine yields carbon dots bearing selenocyanate and carboxylate groups (CD-SeCN) that allow for tuning the hydrosolubility. CD-SeCN has a Se content of 0.36 μmol per mg of nanoparticles, and they show the typical photoluminescence of carbon dots. The selenocyanate groups (SeCN) exhibited glutathione peroxidase-like activity and cytotoxicity. Data show that antioxidant behavior differs between normal and tumor cells, and the evaluation on HEK293 and A549 cells reveals that the toxicity of CD-SeCN depends on dose, time, and intracellular glutathione (GSH) content. The toxicity of CD-SeCN decreases with the time of incubation and the cell death mechanism switches from necrosis to apoptosis, indicating that CD-SeCN is neutralized. Additionally, high levels of intracellular GSH exert a protective effect. These results support a pharmacological potential in cancers with low levels of intracellular GSH. The use of AA-CD as nanoplatforms is a general strategy that paves the way for the engineering of advanced nanosystemsSpanish institution Ministerio de Ciencia, Innovacion y Universidades (No. CTQ2017- 86125-P)Unit of Excellence in Chemistry Applied to Biomedicine and the EnvironmentCentro de Instrumentacion Cientifica (Universidad de Granada)Universidad de Granada/CBUASpringer Natur