Self-learning through the PhysioExTM 9.0 simulator as a teaching tool in Veterinary Physiology. The opinion of the students

[EN] Self-learning has been proposed as an active and plausible methodology to promote the capability of students to reach assigned objectives. During the academic year of 2016-2017, the course of Veterinary Physiology (included in the degree of Veterinary Medicine, University of Murcia, Murcia, Spain) was given using a self-learning method through the computer simulator PhysioExTM 9.0. The practice consisted in  solving 6 exercises, performing simulated laboratory actions, knowing the consequences of each of their actions and answering a series of questions that were discussed afterwards with their classmates. The objective of this learning methodology was to teach students to work independently as well as a team member, promoting their skills to solve problems that might appear later in their professional life. After the practice, the students completed a voluntary survey whose results showed a satisfying opinion about using this self-learning methodology, reaching an average score on the proposed statements (a total of 7) between 4.01 and 4.71 on a Likert scale from 1 to 5. Additionally, the students associated the practice with concepts as ‘classmates’, ‘doubts’, ‘dynamic’, ‘better’, ‘help’ and ‘knowledge’. In conclusion, this activity increased the collaborative learning process of students and enhanced dynamism in class.http://ocs.editorial.upv.es/index.php/HEAD/HEAD18Soriano Úbeda, C.; García Vázquez, F. (2018). Self-learning through the PhysioExTM 9.0 simulator as a teaching tool in Veterinary Physiology. The opinion of the students. Editorial Universitat Politècnica de València. 407-414. https://doi.org/10.4995/HEAD18.2018.8005OCS40741

Curvature and velocity of methane-air Bunsen flame tips

PIV and photographic recording are used to measure the velocity of the fresh gas and the shape of the reaction layer in a region around the tip of a methane- air Bunsen flame attached to a cylindrical burner. The results compare well with numerical simulations carried out with an infinite activation energy reaction model. The experimental and numerical results confirm that the well-known linear relation between flame velocity and flame stretch derived from asymptotic theory for weakly curved and strained flames is valid for small and moderate values of the flame stretch if the modified definition of stretch introduced by Echekki and Mungal (Proc Combust Inst 23:455–461,1990) and Poinsot et al. (Combust Sci Technol 81:45–73,1992) is used. However, the relation between flame velocity and modified stretch ceases to be linear and approaches a square root law for large values of the stretch, when the curvature of the flame tip becomes large compared to the inverse of the thickness of a planar flam

Measurement of the burning velocity of strongly curved methane-air flames

An experimental and numerical study has been carried out of the region around the tip of a methane-air premixed flame attached to a circular laminar jet burner. On the experimental side, photographic records and PIV have been used to measure the shape of the reaction layer and the velocity of the gas around the tip of the flame. The numerical part of the study includes simulations of stationary axisymmetric flames with infinitely high activation energy reactions. The experimental and numerical results compare well with each other and allow to determine the curvature of the reaction layer at the tip and the velocity and strain rate of the fresh gas flow along the axis of the burner. These data, together with the planar flame velocity determined by extrapolating the velocity of the flame at the tip to the limit of zero stretch, are used to assess the well-known linear flame-velocity/flame-stretch relationship originally proposed by Markstein and later derived in the asymptotic limit of weakly curved and strained flames [1, 2], as well as the phenomenological modification proposed more recently by Mungal and coworker

Curvature and burning velocity of Bunsen Flame tips.

The burning velocity of a premixed flame propagating in a given flammable mixture is known to depend on the difference between the curvature of the flame and the so-called curvature of the flow, which is the strain rate of the flow of fresh gas along the normal to the flame divided by the burning velocity of the planar flame. The difference between the local burning velocity and the burning velocity of a planar flame in a gas at rest is proportional to the difference of the flame and flow curvatures. The proportionality factor is the product of the burning velocity of the planar flame and the Markstein length, which is an intrinsic property of the flame that characterizes its dynamics. The Markstein length can be determined experimentally by simultaneously measuring the curvature of the flame and the strain rate of the flow. To achieve this goal, we have set up a laminar jet burner and used two PIV systems to measure the gas flow velocity in two perpendicular planes normal to the flame. Each PIV system is composed by two Q-switched Nd: YAG pulse lasers (New Wave, maximum 120 mJ/pulse at 532 nm wavelength), a double-shuttered cross-correlation camera (PCO, 1392 × 1040 pixels) and a pulse generator (ILA GmbH) to synchronize all the components as well as the two PIV systems. Oil droplets are used for tracking the flow and the flame. They are formed by condensation after oil evaporation in a seeding chamber placed in the air line. Seeded air and fuel gas (CO,H2, CH4) are mixed in a settling chamber upstream of the burner and burned in a stationary Bunsen flame. The oil droplets evaporate in the flame preheating region, thereby allowing a dual tomography of the front

Local burning velocity in a Bunsen jet flame

A PIV-based system has been set-up for the simultaneous measurement of the local burning velocity of premixed flames and the flame stretch due to the flame front curvature and the incoming flow strain rate. For moderately short jet flames, these measurements allow an indirect determination of the Markstein length, according to Clavin and Joulin (C–J) theory. For tall flames, the flame curvature becomes relatively large in a region around the tip where the C–J theory breaks down. However, our experiments confirm the appearance of a new linear relation between burning velocity and curvature at the flame tip. This relation defines a new proportionality factor which is probably associated to the evolution from rounded tips to slender tips when the jet velocity is increased

Desarrollo de electrodos para baterías de litio-azufre

Tesis (Lic. en Física)--Universidad Nacional de Córdoba, Facultad de Matemática, Astronomía, Física y Computación, 2018.Este trabajo de investigación se basó en el desarrollo de materiales activos para baterı́as litio-azufre. Se hizo principal énfasis en la modificación del separador para mejorar el desempeño electroquı́mico de la baterı́a. Para ello, se sintetizaron nano fibras de carbono usando como precursor una arcilla natural denominada sepiolita. La caracterización fisicoquı́mica indicó un alto grado de grafitización del carbono, y se determinó que posee una estructura desordenada con dimensiones nanométricas. En cuanto a las propiedades electroquı́micas se encontró un sustancial aumento en la capacidad y la ciclabilidad de la baterı́a respecto del estado del arte que puede encontrarse en la bibliografı́a actual de sistemas similares. Ası́, se obtuvo una capacidad especı́fica de alrededor de 1000 mAh g −1 y una excelente ciclabilidad de más de 150 ciclos con una elevada eficiencia coulómbica.This research was based on the development of active materials for lithium-sulfur batteries. Emphasis was placed on coating the separator to improve de electrochemical performance of the battery. To this aim, carbon nano fibers were synthesized using as precursor a natural clay named sepiolite. The physical-chemical characterization showed a high degree of carbon graphitization, and a disordered structure with nanometric dimension was determined. As regards the electrochemical properties, a substantial improvment was found in the capacity and the cyclability of the battery compared with those found in the actual literature for similar systems. Thus, a specific capacity of 1000 mAh g−1 was obtained, an excellent cyclability of more than 150 cycles with a high coulombic efficiency.2020-06-18García Soriano, Francisco Javier. Universidad Nacional de Córdoba. Facultad de Matemática, Astronomía, Física y Computación; Argentina

Implantación en Mallorca de un programa de Tratamiento multimodal de la Carcinomatosis Peritoneal mediante Quimioterapia Sistémica, Cirugía Citorreductora y Quimioterapia Intraperitoneal Hipertérmica (HIPEC)

Introducción: Las investigaciones de Sugarbaker et al demostraron desde principios de los 90 que muchos tumores de origen colorrectal y apendicular con extensión peritoneal pueden permanecer limitados al abdomen durante períodos relativamente largos antes de desarrollar metástasis a distancia. Con ello, la carcinomatosis peritoneal pasó de considerarse desde una perspectiva sistémica y prácticamente terminal a concebirse como una enfermedad loco-regional, susceptible de rescate quirúrgico y oncológico, con un aumento de la supervivencia. Los estudios experimentales de la cirugía citorreductora radical asociada a la quimioterapia intraperitoneal hipertérmica ofrecen mejores resultados en términos de supervivencia a largo plazo y de calidad de vida que los tratamientos convencionales. El tratamiento actual de la carcinomatosis peritoneal es multimodal, con tres líneas de acción: 1. Quimioterapia intravenosa preoperatoria de inducción; 2. Cirugía citorreductora y peritonectomía, y 3. Quimioterapia intraperitoneal hipertérmica. Su base científica se fundamenta en el sinergismo entre la hipertermia y varios quimioterápicos (Mitomicina-C, Cisplatino, Oxaliplatino, etc), en la citotoxicidad directa del calor sobre las células tumorales y en las ventajas farmacocinéticas de la quimioterapia administrada por vía intraperitoneal. Metodología: Objetivos del Programa: 1. Desarrollo del Protocolo de tratamiento multimodal oncológico y quirúrgico. 2. Formación continuada del grupo de trabajo multidisciplinario. 3. Formación continuada en el manejo de la técnica de perfusión de quimioterapia intraperitoneal hipertérmica. 4. Aplicación de un protocolo de seguridad laboral. 5. Definición de indicadores de resultados. 6. Diseño de base de datos informatizada para explotación de resultados. 7. Seguimiento y registro de morbilidad y mortalidad. 8. Seguimiento y análisis de supervivencia a medio y largo plazo. Evaluación clínica preoperatoria y estudio de extensión tumoral. 1. Indicaciones clínicas. Tipos de tumores. 2. Selección de pacientes. Criterios de inclusión y de exclusión. 3. Evaluación oncológica preoperatoria. 4. Evaluación radiológica preoperatoria. 5. Algoritmo de actuación. 6. Seguimiento de pacientes. 7. Seguridad laboral. Resultados: Hace cinco años se puso en marcha en el Hospital Son Llàtzer el programa completo de cirugía citorreductora con quimioterapia intraperitoneal hipertérmica para el tratamiento de la carcinomatosis peritoneal. Se han intervenido 46 pacientes (40 mujeres y 6 hombres), con una edad media de 58.3 años (47-73 años). De los 46 pacientes, 30 lo eran con cáncer de ovario, y en ellos se realizó cirugía citorreductora seguida de quimioterapia sistémica sin aplicación de quimioterapia intraperitoneal. El programa de cirugía citorreductora y quimioterapia intraperitoneal se compone de 17 pacientes en los que se realizaron un total de 20 procedimientos. El origen del tumor fue colorrectal en 11 casos, apendicular en 4 casos, gástrico en un caso y un mesotelioma peritoneal multiquísitico difuso. En 9 casos se realizó quimioterapia intraperitoneal normotérmica y en 11 casos quimioterapia intraperitoneal hipertérmica (HIPEC). La mortaliad perioperatoria fue de un 4.3% (tres pacientes). El índice de resecabildad tumoral fue de un 90.9%. En 17 casos (85%), se pudo conseguir una resección completa (CC-0). La morbilidad global fue de un 40%, siendo la complicación más frecuente la infección de catéter central. Fueron reintervenidos tres pacientes (hemorragia, fístula duodenal e isquemia mesentérica segmentaria). La duración media de la intervención fue de 6.5 horas y la estancia media de 18.2 días. La supervivencia media de los pacientes con diseminación peritoneal de origen colorrectal y apendicular ha sido de 27 y 31 meses respectivamente. La supervivencia global de los pacientes con carcinomatosis peritoneal de origen colorrectal al año, dos y tres años fue del 71%, 60% y 50% respectivamente. Conclusiones: a) La aplicación de un tratamiento multidisciplinar y multimodal puede mejorar de forma significativa la supervivencia en un grupo específico de pacientes con carcinomatosis peritoneal; b) Este tratamiento es costoso y complejo y supone una importante carga de trabajo para los profesionales y las instituciones, por lo que es esencial aplicar criterios rigurosos de selección de pacientes, fundamentados en la experiencia y en la evaluación por equipos multidisciplinares. Es esencial el diagnóstico precoz, el tratamiento de las complicaciones, el seguimiento de los pacientes y la evaluación continua de los resultados de morbilidad y supervivencia. c) los estudios randomizados en curso aportarán previsiblementeIntroduction: Research promoted since the early nineties by Sugarbaker et al in Washington, have demonstrated that many tumors of colorectal and appendiceal origen with peritoneal extension, may remain limited to the abdomen during relatively long periods before developing distant metastases. These findings have radically altered the consideration of peritoneal carcinomatosis from a systemic and almost terminal state, to a locoregional disease, with possibility of surgical and oncological rescue, and thus, increasing the survival. The results of experimental studies of radical cytoreductive surgery associated with hyperthermic intraperitoneal chemotherapy, have demonstrated better results in terms of long-term survival and quality of life than conventional treatments. The rationale for the current treatment of peritoneal carcinomatosis is organized around a multimodal treatment with three courses of action: 1. Preoperative intravenous induction chemotherapy, 2. Cytoreductive surgery and peritonectomy, and 3. Hyperthermic intraperitoneal chemotherapy (HIPEC). The scientific basis of this multimodal treatment is based on the synergism between the hyperthermia and several cytostatic agents (mitomycin-C, cisplatin, oxaliplatin, etc.), the direct heat cytotoxicity on tumor cells, and the pharmacokinetic advantages of chemotherapy administered intraperitoneally. Methodology: Program Objectives were the following: 1. Development of Multimodal surgical and oncologic treatment protocol; 2. Continuing education of the multidisciplinary group; 3. Ongoing training in the hyperthermic intraperitoneal perfusion chemotherapy; 4. Application of a Work Safety Protocol; 5. Definition of indicators; 6. Design of database for exploitation of results; 7. Monitoring of morbidity and mortality, and 8. Monitoring and analysis of survival. Clinical evaluation and preoperative tumor extension study. 1. Clinical Indications. Types of tumors; 2. Patient selection. Inclusion and exclusion criteria; 3. Preoperative Evaluation Oncology; 4. Preoperative radiological evaluation; 5. Clinical pathway algorithm; 6. Patients follow-up, and 7. Laboral safety. Results: Five years ago, we started cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for treatment of peritoneal carcinomatosis in the Hospital Son Llàtzer. 46 patients were operated (40 women and 6 men) with a mean age of 58.3 years (47-73 years). Of these 46 patients, 30 were patients with ovarian cancer, and underwent cytoreductive surgery followed by chemotherapy without applying systemic intraperitoneal chemotherapy. The program consisted of 17 patients who underwent a total of 20 procedures. The origin of the tumor was colorectal in 11 cases, appendiceal in 4 cases, gastric in 1 case, and one case with a diffuse multicystic peritoneal mesothelioma. The intraperitoneally chemotherapy administered was normothermic in 9 patients, and hyperthermic (HIPEC) in 11 cases. The perioperative mortality was 4.3% (three patients). The resectability index was 90.9%. In 17 cases (85%) it was possible to get a complete resection (CC-0). Overall morbidity was 40%. The most frequent complication was central catheter infection. Three patients required reoperation (postoperative bleeding, duodenal fistula, and segmental mesenteric ischemia). The mean operative duration was 6.5 hours. The average stay was 18.2 days. The median survival of patients with peritoneal dissemination of appendiceal and colorectal origin was 27 and 31 months respectively. Overall survival of patients with peritoneal carcinomatosis of colorectal origin was at one, two, and three years 71%, 60% and 50% respectively. Conclusions: a) The application of a multidisciplinary and multimodal treatment can significantly improve survival in a specific group of patients with peritoneal carcinomatosis. b) This treatment is expensive, complex and represents a significant workload for professionals and institutions, so it is essential to apply strict criteria for patient selection, based on experience and the evaluation by multidisciplinary teams. Similarly, it is essential to achieve an early diagnosis, treatment of complications, patient monitoring, and continuous evaluation of morbidity outcomes and survival. c) Randomized studies currently underway will provide more evidence on the expected benefit of this treatment, and establish lines to improve results

Residuos de coco. Arte y vermicompostado para su reutilización

[EN] Coconut waste is difficult to eliminate and although it is useful as a substrate in gardening, its long life makes it useful for other activities, being widely used within the art to make crafts and decorative works both in jewelry, ornaments, instruments, etc.. In addition, some parts of the coconut with difficult reuse after agro-industrial use can be processed by composting transforming it into a useful resource as a fertilizer, given its high proportion of nutrients. Its usefulness in art is mentioned and the results related to the reuse of coconut waste from a start-up in Ecuador after the agro-industrial use of coconut are presented. The composted waste was prepared by adding rabbit manure and water, and analyzed at different stages of the composting process. During the waste transformation process, parameters such as temperature and humidity were controlled, a high temperature is required to disinfect the final product and maintaining humidity around 60% to facilitate the process. The results show the nutrient richness of the final product, suitable for use as a fertilizer, having begun trials to be used also as a substrate v for plant development. The study is part of a Cooperation Project of the Polytechnic University of Valencia in the School of Agronomy and Rural Environment.[ES] Los residuos de coco son difíciles de eliminar y aunque presentan utilidad como sustrato en jardinería, su larga vida los hace útil para otras actividades, siendo muy utilizado dentro del arte para realizar manualidades y obras decorativas tanto en joyeria, adornos, instrumentos, etc. Además algunas partes del coco con dificil reutilización tras u uso agroindustrial puede procesarse por compostado transformándolo en un recurso útil como fertilizante, dada su alta proporción en nutrientes. Se menciona su utilidad en el arte y se presentan los resultados relativos a la reutilización de residuos de coco procedentes de una empresa emergente de Ecuador después de la utilización agroindustrial del coco. Los residuos compostados se prepararon adicionando estiercol de conejo y agua, y se analizaron en diferentes etapas del proceso de compostaje. Durante el proceso de transformación del residuo se controlaron parámetros como la temperatura y la humedad, se precisa una temperatura elevada para realizar la desinfección del producto final y manteniendo la humedad alrededor del 60% para facilitar el proceso. Los resultados muestran la riqueza en nutrientes del producto final, apto para su utilización como fertilizante, habiéndose iniciado los ensayos para poder utilizarse también como sustrato v para el desarrollo vegetal. El estudio se enmarca dentro de un Proyecto de Cooperación de la Universitat Politécnica de Valencia en la Escuela de Agronomia y del Medio Rural.Trabajo realizado en el marco del Proyecto de Cooperación de la Universitat Politècnica de València. Programa Adisedo Cooperación. Años 2020-2022. «TÍTULO DEL PROYECTO: Evaluación de la sostenibilidad del establecimiento de una fábrica artesana de productos de coco en la subregión de Sanquianga (departamento de Nariño, Colombia)».Soriano Soto, MD.; García Mares, FJ.; García-España Soriano, L. (2022). Residuos de coco. Arte y vermicompostado para su reutilización. En Actas del III Congreso Internacional sobre Patrimonio Alimentario y Museos. Editorial Universitat Politècnica de València. 281-288. https://doi.org/10.4995/EGEM2021.2021.14899OCS28128