Scale of achievement self--efficacy for waterpolo goalkeepers

Una variable determinante en el rendimiento deportivo es la percepción de autoeficacia, de tal manera que los individuos con mayor percepción de autoeficacia son al mismo tiempo los que mejor afrontan las acciones motrices y los que buscan más retos deportivos. Al respecto, una pertinente línea de investigación es la creación de instrumentos que posibiliten la medida de la percepción de autoeficacia en deportes colectivos. Este trabajo presenta la Escala de autoeficacia de logro para porteros de waterpolo, siendo un instrumento original e inédito que permite evaluar la autoeficacia de logro de los porteros de waterpolo en la detención de lanzamientos. Su comunicación en la Revista Española de Educación Física y Deportes, tanto en idioma español como en lengua inglesa, permite su utilización en investigación y campeonatos internacionales. Esta es la primera escala a nivel internacional sobre autoeficacia en waterpolo.Perception of self-efficacy is a relevant variable in sport performance. In fact, sportsmen who have a good perception of self-efficacy are better in movement actions and sport challenges than ones with a misperception. In this regard, a pertinent line of research is the creation of instruments to measure of perception of self-efficacy in team sports. In this paper is presented the Scale of achievement self-efficacy for waterpolo goalkeepers. This questionnaire is an original instrument. Its publication in the Spanish Journal of Physical Education and Sports, both in Spanish and in English language, allows their use in research and international championships. This is the first instrument to measure self-efficacy in water polo

Application of a behavioral objective evidence of evaluation of the influence of others in the performance in soccer

Se presenta el desarrollo de una prueba objetiva basada en el uso de un dinamómetro manual para analizar la influencia que ejerce la presencia de otras personas significativas, como el entrenador o los compañeros, en jugadores de fútbol infantil, cadete y juvenil de la Comunidad Autónoma de Madrid. Su aplicación permite superar las limitaciones presentadas por las pruebas de autoinforme tradicionales, analizando la validez convergente que tienen los resultados obtenidos con los encontrados en la escala de “Influencia de la evaluación del rendimiento” del cuestionario de características psicológicas relacionadas con el rendimiento deportivo factorizado CPRD-f (Olmedilla, García y Martínez, 2006). Los resultados obtenidos muestran la utilidad del empleo de una técnica objetiva como la planteada en el análisis de la influencia que tienen los otros en el rendimiento individualAn objective test, by using a hand dynamometer is presented in order to analyze the influence of significant people as the coach or the team mates in grip strength performance of young soccer players. Through this objective test was possible to overcome the methodological limitations presented by the traditional self-reported measures. The convergent validity between the dynamometer test results and the values obtained from the “Influence of performance evaluation scale” of the Psychological Characteristics related to Sport Performance factored Questionnaire CPRD-f (Olmedilla, García y Martínez, 2006) was also analyzed. The results showed the usefulness of an objective test as the hand dynamometer to analyze the influential role of significant people on individual performanceApresentamos o desenvolvimento de uma prova objetiva baseada no uso de um dinamômetro manual para analisar a influencia que exerce a presença de outras pessoas significativas, como o treinador ou os companheiros nos jogadores de futebol infantis, cadetes e juniores da Comunidad Autónoma de Madrid. Sua aplicação permite superar as limitações apresentadas pelas provas auto-informes tradicionais, analisando a validez convergente que tem os resultados obtidos com os encontrados na escala de “influencia da avaliação do rendimento” do questionário de características psicológicas relacionadas com o rendimento esportivo fatorizado CPRD-f (Olmedilla, García y Martínez, 2006). Os resultados obtido mostram a utilidade da aplicação técnica objetiva como a proposta na analises da influencia que tem os outros no rendimento individualEsta investigación ha sido parcialmente financiada gracias al proyecto de I+D+I MICINN PSI2011-2700

An ancestry informative marker set for determining continental origin: validation and extension using human genome diversity panels

<p>Abstract</p> <p>Background</p> <p>Case-control genetic studies of complex human diseases can be confounded by population stratification. This issue can be addressed using panels of ancestry informative markers (AIMs) that can provide substantial population substructure information. Previously, we described a panel of 128 SNP AIMs that were designed as a tool for ascertaining the origins of subjects from Europe, Sub-Saharan Africa, Americas, and East Asia.</p> <p>Results</p> <p>In this study, genotypes from Human Genome Diversity Panel populations were used to further evaluate a 93 SNP AIM panel, a subset of the 128 AIMS set, for distinguishing continental origins. Using both model-based and relatively model-independent methods, we here confirm the ability of this AIM set to distinguish diverse population groups that were not previously evaluated. This study included multiple population groups from Oceana, South Asia, East Asia, Sub-Saharan Africa, North and South America, and Europe. In addition, the 93 AIM set provides population substructure information that can, for example, distinguish Arab and Ashkenazi from Northern European population groups and Pygmy from other Sub-Saharan African population groups.</p> <p>Conclusion</p> <p>These data provide additional support for using the 93 AIM set to efficiently identify continental subject groups for genetic studies, to identify study population outliers, and to control for admixture in association studies.</p

Utilización de Internet para la enseñanza de sistemas digitales

Las nuevas tecnologías de la información y la comunicación han creado grandes expectativas en educación, pues permiten superar las limitaciones de tiempo y lugar, abaratando incluso los costes. Además, no debe olvidarse que los medios informáticos ofrecen una serie de características que favorecen el aprendizaje significativo a través de actividades de tipo interactivo. Por eso, nos parece importante su aplicación a la enseñanza de la Informática, y en particular de los sistemas digitales. En esta ponencia se presenta un sistema multimedia, basado en Internet, que se está desarrollando con el fin de aplicarlo a la docencia de sistemas digitales en la asignatura Fundamentos de Informática. La ponencia presenta una descripción general de dicho sistema, así como de las herramientas y métodos utilizados para su construcción

The structure of Leptospira interrogans GAPDH sheds light into an immunoevasion factor that can target the anaphylatoxin C5a of innate immunity

Leptospirosis is a neglected worldwide zoonosis involving farm animals and domestic pets caused by the Gram-negative spirochete Leptospira interrogans. This bacterium deploys a variety of immune evasive mechanisms, some of them targeted at the complement system of the host’s innate immunity. In this work, we have solved the X-ray crystallographic structure of L. interrogans glyceraldehyde-3-phosphate dehydrogenase (GAPDH) to 2.37-Å resolution, a glycolytic enzyme that has been shown to exhibit moonlighting functions that potentiate infectivity and immune evasion in various pathogenic organisms. Besides, we have characterized the enzyme’s kinetic parameters toward the cognate substrates and have proven that the two natural products anacardic acid and curcumin are able to inhibit L. interrogans GAPDH at micromolar concentration through a noncompetitive inhibition modality. Furthermore, we have established that L. interrogans GAPDH can interact with the anaphylatoxin C5a of human innate immunity in vitro using bio-layer interferometry and a short-range cross-linking reagent that tethers free thiol groups in protein complexes. To shed light into the interaction between L. interrogans GAPDH and C5a, we have also carried out cross-link guided protein-protein docking. These results suggest that L. interrogans could be placed in the growing list of bacterial pathogens that exploit glycolytic enzymes as extracellular immune evasive factors. Analysis of the docking results indicates a low affinity interaction that is consistent with previous evidence, including known binding modes of other α-helical proteins with GAPDH. These findings allow us to propose L. interrogans GAPDH as a potential immune evasive factor targeting the complement system

Factors influencing participation in colorectal cancer screening programs in Spain

To analyze the sociodemographic and organizational factors influencing participation in population-based colorectal cancer screening programs (CRCSP) in Spain, a retrospective study was conducted in a cohort of people invited to participate in the first 3 screening rounds of 6 CRCSP from 2000 to 2012. Mixed logistic regression models were used to analyze the relationship between sociodemographic and organizational factors, such as the type of fecal occult blood test (FOBT) used and the FOBT delivery type. The analysis was performed separately in groups (Initial screening-first invitation, Subsequent invitation for previous never-responders, Subsequent invitation-regular, Subsequent invitation-irregular intervals). The results showed that, in the Initial screening-first invitation group, participation was higher in women than in men in all age groups (OR 1.05 in persons aged 50–59 years and OR 1.12 in those aged 60–69 years). Participation was also higher when no action was required to receive the FOBT kit, independently of the type of screening (Initial screening-first invitation [OR 2.24], Subsequent invitation for previous never-responders [OR 2.14], Subsequent invitation-regular [OR 2.03], Subsequent invitation-irregular intervals [OR 9.38]) and when quantitative rather than qualitative immunological FOBT (FIT) was offered (Initial screening-first invitation [OR 0.70], Subsequent invitation for previous never-responders [OR 0.12], Subsequent invitation-regular [OR 0.20]) or guaiac testing (Initial screening-first invitation [OR 0.81], Subsequent invitation for previous never-responders [OR 0.88], Subsequent invitation-regular [OR 0.73]). In conclusion, the results of this study show that screening participation could be enhanced by inclusion of the FOBT kit with the screening invitation and the use of the quantitative FIT.This Project was funded by the Fondo de Investigación Sanitario with cofunding from FEDER [PI12/00944