28 research outputs found

    Discussant\u27s response no. 2 to Illegal acts: What is the auditor\u27s responsibility?

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    https://egrove.olemiss.edu/dl_proceedings/1077/thumbnail.jp

    International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways.

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    Primary biliary cirrhosis (PBC) is a classical autoimmune liver disease for which effective immunomodulatory therapy is lacking. Here we perform meta-analyses of discovery data sets from genome-wide association studies of European subjects (n=2,764 cases and 10,475 controls) followed by validation genotyping in an independent cohort (n=3,716 cases and 4,261 controls). We discover and validate six previously unknown risk loci for PBC (Pcombined<5 × 10(-8)) and used pathway analysis to identify JAK-STAT/IL12/IL27 signalling and cytokine-cytokine pathways, for which relevant therapies exist

    International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

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    Fundamental financial accounting concepts

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    xxxvii, 761 p. ; 28 cm

    Survey of Accounting

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    xxxv, 683 p. : Ill.; 28 c

    Survey of accounting

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    xxxii, 688 p.; 29 cm

    Survey of accounting

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    xxxiii, 688 hlm. : ilus. ; tab. ; 27,5 cm
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