Central Stars of Planetary Nebulae in Galactic Open Clusters: Providing additional data for the White Dwarf Initial-to-Final-Mass Relation

Accurate (<10%) distances of Galactic star clusters allow precise estimation of the physical parameters of any physically associated Planetary Nebula (PN) and also that of its central star (CSPN) and its progenitor. The progenitor's mass can be related to the PN's chemical characteristics and furthermore, provides additional data for the widely used white dwarf (WD) initial-to-final mass relation (IFMR) that is crucial for tracing the development of both carbon and nitrogen in entire galaxies. To date there is only one PN (PHR1315- 6555) confirmed to be physically associated with a Galactic open cluster (ESO 96 -SC04) that has a turn-off mass $\sim$2 M$_{\odot}$. Our deep HST photometry was used for the search of the CSPN of this currently unique PN. In this work, we present our results.Comment: 2 pages, 1 figure, IAU343 Synposiu

New Galactic Planetary Nebulae selected by radio and multi-wavelength characteristics

We have used the Cornish radio catalogue combined with the use of multi-wavelength data to identify 62 new Planetary Nebula (PN) candidates close to the Galactic mid-plane. Of this sample 11 have weak optical counterparts in deep narrow band H$\alpha$ imaging that allows their spectroscopic follow-up. We have observed eight of these candidates spectroscopically, leading to the confirmation of 7 out of 8 as PNe. All but one of our sample of newly detected PNe appear to be of Type I chemistry with very large [NII]/H$\alpha$ ratios. This indicates that our selection method heavily favours detection of this kind of PN. Cornish is a low Galactic latitude survey where young objects and Type I PNe (thought to derive from higher mass progenitors) are more plentiful, but where optical extinction is large. The very high success rate in correctly identifying PNe in this zone proves the efficacy of our radio and multiple multi-wavelength diagnostic tools used to successfully predict and then confirm their PN nature, at least in the cases where an optical counterpart is found and has been observed. The study reinforces the effective use of a combination of multi-wavelength and optical data in the identification of new Galactic PNe and especially those of Type I chemistries whose dusty environments often prevents their easy detection in the optical regime alone.Comment: 13 pages, 5 figure

Further Studies of the Association of Planetary Nebula BMP J16135406 with Galactic Open Cluster NGC 6067

Planetary Nebulae (PNe) that are physical members of Galactic open clusters are powerful probes that allow precise determination of their distance and crucially their initial mass on the main sequence. Here, we revisit the physical association of the PN BMP J1613–5406 with the open cluster NGC 6067 and present our preliminary results based on our new ESO/VLT FORS2 data. Our PN spectral data permit the calculation of a precise radial velocity and reddening to the PN that shows a tight consistency with the literature corresponding cluster parameters including importantly the radial velocity. Our measurements, combined with the agreement between the distances of the two objects and the fact that the PN is located well within the cluster boundaries, confirm that the PN is physically associated with the cluster. The cluster has a turn-off mass of around 5 solar masses that indicates a PN initial mass of around 5.6 solar masses. This is closer to the theoretical lower limit of core-collapse supernova formation than has ever been previously observed, providing a unique opportunity for further stellar and Galactic chemical evolution studies using this system

Improvements in electrochemical glucose biosensors

Diabetes is one of the leading causes of death and disability in the world. Even though insulin was discovered in 1920, an intense research on diabetes has been conducted during the last five decades and this is because of the market size. The huge demand is creating the need for the development of new approaches. This project involved the research aimed at better understanding and improvements in performance of glucose biosensors. In general, high surface area electrodes are desired as the high surface area provides more active sites for electrochemical reactions, and hence higher kinetic rate capability. Therefore, the determination of the active electrochemical surface area of the electrode is very important. A study has been conducted to determine the real electrochemical surface area of the Pelikan screen printed electrodes (SPEs) and a method has been optimised and established by Pelikan for the evaluation of their SPEs. Another very important issue that most of the current blood glucose monitoring tests are facing is the haematocrit effect, since the haematocrit differences observed in the blood samples can significantly affect glucose measurements. Therefore a study has been conducted in order to observe the absorption of the blood samples into the working electrode paste according to the haematocrit level. The second part of the study included the characterisation of the novel conjugated polymer made of N-(N, N’ diethyldicarbamoyl ethyl amido ethyl) aniline (NDDEAEA), the optimization of the conditions for the electrochemical polymerization, their application in grafting and finally the development of NDDEAEA based glucose biosensor. The new conducting polymer, acted as a matrix for the biosensor fabrication in this study, possesses macroiniferter properties and is capable of initiation free radical initiated addition polymerisation after formation of the polyaniline (PANI) material while preserving or even enhancing some of the PANI’s electrochemical properties. This material can potentially be used in the construction of novel Pelikan electrodes with enhanced integration functionalities, e.g. grafting non adhesive polymer coatings to assure that the poor performance in sensors as a result of impact of blood components can be mitigated. The final study included the development and optimisation of the reaction conditions for grafting a hyperbranched polymer onto the surface of the multi walled carbon nanotubes (MWCNT), using the A3 and B2 approach (described below). The aim of this work was achieving further increase in the sensitivity of Pelikan sensors.EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Autoantibodies against type I IFNs in patients with critical influenza pneumonia

In an international cohort of 279 patients with hypoxemic influenza pneumonia, we identified 13 patients (4.6%) with autoantibodies neutralizing IFN-alpha and/or -omega, which were previously reported to underlie 15% cases of life-threatening COVID-19 pneumonia and one third of severe adverse reactions to live-attenuated yellow fever vaccine. Autoantibodies neutralizing type I interferons (IFNs) can underlie critical COVID-19 pneumonia and yellow fever vaccine disease. We report here on 13 patients harboring autoantibodies neutralizing IFN-alpha 2 alone (five patients) or with IFN-omega (eight patients) from a cohort of 279 patients (4.7%) aged 6-73 yr with critical influenza pneumonia. Nine and four patients had antibodies neutralizing high and low concentrations, respectively, of IFN-alpha 2, and six and two patients had antibodies neutralizing high and low concentrations, respectively, of IFN-omega. The patients' autoantibodies increased influenza A virus replication in both A549 cells and reconstituted human airway epithelia. The prevalence of these antibodies was significantly higher than that in the general population for patients 70 yr of age (3.1 vs. 4.4%, P = 0.68). The risk of critical influenza was highest in patients with antibodies neutralizing high concentrations of both IFN-alpha 2 and IFN-omega (OR = 11.7, P = 1.3 x 10(-5)), especially those <70 yr old (OR = 139.9, P = 3.1 x 10(-10)). We also identified 10 patients in additional influenza patient cohorts. Autoantibodies neutralizing type I IFNs account for similar to 5% of cases of life-threatening influenza pneumonia in patients <70 yr old

Improvements in electrochemical glucose biosensors

Diabetes is one of the leading causes of death and disability in the world. Even though insulin was discovered in 1920, an intense research on diabetes has been conducted during the last five decades and this is because of the market size. The huge demand is creating the need for the development of new approaches. This project involved the research aimed at better understanding and improvements in performance of glucose biosensors. In general, high surface area electrodes are desired as the high surface area provides more active sites for electrochemical reactions, and hence higher kinetic rate capability. Therefore, the determination of the active electrochemical surface area of the electrode is very important. A study has been conducted to determine the real electrochemical surface area of the Pelikan screen printed electrodes (SPEs) and a method has been optimised and established by Pelikan for the evaluation of their SPEs. Another very important issue that most of the current blood glucose monitoring tests are facing is the haematocrit effect, since the haematocrit differences observed in the blood samples can significantly affect glucose measurements. Therefore a study has been conducted in order to observe the absorption of the blood samples into the working electrode paste according to the haematocrit level. The second part of the study included the characterisation of the novel conjugated polymer made of N-(N, N’ diethyldicarbamoyl ethyl amido ethyl) aniline (NDDEAEA), the optimization of the conditions for the electrochemical polymerization, their application in grafting and finally the development of NDDEAEA based glucose biosensor. The new conducting polymer, acted as a matrix for the biosensor fabrication in this study, possesses macroiniferter properties and is capable of initiation free radical initiated addition polymerisation after formation of the polyaniline (PANI) material while preserving or even enhancing some of the PANI’s electrochemical properties. This material can potentially be used in the construction of novel Pelikan electrodes with enhanced integration functionalities, e.g. grafting non adhesive polymer coatings to assure that the poor performance in sensors as a result of impact of blood components can be mitigated. The final study included the development and optimisation of the reaction conditions for grafting a hyperbranched polymer onto the surface of the multi walled carbon nanotubes (MWCNT), using the A3 and B2 approach (described below). The aim of this work was achieving further increase in the sensitivity of Pelikan sensors

Exploring Free Floating Planets with Microlensing

About one year ago, the MOA microlensing team announced the discovery of a free floating planet population with the method of gravitational microlensing (Sumi et al. 2011). In this thesis, we test the possibility of these planets being in reality bound but getting confused as free floating because of the shape of their light curve. Following a review of extrasolar planets and a description of the method of gravitational microlensing, we simulate binary lensing events produced by several combinations of parameters for the source star, the lens star and the planet, the light curves of which, afterwards, are fitted to the light curve of a single lensing event. After rejecting some of the simulated events because of their unclear light curve, we determine which of the simulated binary microlensing events produce a light curve that cannot be differentiated to that of a free floating planet, their fitting parameters, the parameters that produced them and their relative frequency. Our results indicate that, for Jupiter mass free-floating planets, we expect less than 0.1 out of the 1000 events analysed by MOA to look like free floating systems yet be caused by bound planets within 100 AU of their host star. As a result, the comparison of our results with the results of Sumi et al. (2011) reveals that the population of exoplanets that Sumi et al. (2011) detected consists either from actually unbound planets or from bound planets with sky-projected separations from their host, longer than 100 AU

Integrating technological means in small museums: the case of The Historical & Folklore Museum Of Kalamata, Greece

This research aims to address the needs of small and local museums when it comes to the attraction of tourists, both foreign and domestic, through the use of new technological means. As a case study, the Historical & Folklore Museum of Kalamata that is located in the Messenian Prefecture, Greece has been chosen. This museum attracts more than 2000 visitors per year, and this can be considered a great number, taking into consideration its size and complicated layout. In order to make the right suggestions that would fit exactly the needs of the museum, intensive observation sessions took place. Two different sets of questionnaires were prepared and distributed via social media, and after the visitor tours. Moreover, interviews were carried out with all the employees, and also a complete space syntax analysis was conducted so as to outline the interaction between visitor and museum space. The proposals were based on the identified requirements and the space utilization. Some of the technologies proposed are: the creation of a user friendly website, mobile and tablet auto guides (mobile storytelling application), the creation of a computer “corner” on the ground floor for the needs of disabled people, TV screens showing stories and documentaries based on each thematic area of the museum, and VR and AR applications. Moreover, taking into consideration that there are 22 Folklore Museums in the Messenian Prefecture, 6 indoor and outdoor museums in the city of Kalamata, and since the building itself is considered an important architectural element of the city, the creation of an application that would embed the Historical and Folklore Museum of Kalamata in cultural routes of folklore and architectural interest was suggested. The majority of the proposals is low cost and can be easily adapted by small museums.