PHOSPHORUS DIGESTIBILITY AND PHYTATE DEGRADATION IN LONG YEARLINGS AND MATURE HORSES

Much of the phosphorus (P) in grain-based concentrates fed to growing horses is in the form of phytate-P. Little is known about the ability of young horses to degrade phytate-P or whether age affects mineral digestion in horses. The objective of this study was to examine the effect of age on P, calcium (Ca), and magnesium (Mg) digestibility and phytate-P degradation. Four long yearling geldings and 4 mature geldings were fed a diet of alfalfa cubes, timothy cubes and a pelleted concentrate. The diet contained 0.28% total P and 17.4% of that P was in the phytate form. There was a 14-d diet adaptation period followed by a 4-d fecal collection period. There was no difference in apparent P digestibility between the 2 age groups (P \u3e 0.05). Phytate-P disappearance was 94.8% and did not differ between ages (P \u3e 0.05). Apparent Ca digestibility tended to be higher in mature geldings (P = 0.0526), but apparent Mg digestibility did not differ between ages (P \u3e 0.05). Long yearlings have the same ability to digest P and Mg as mature geldings, but more research is needed to determine the effect of age on Ca digestibilities

FACTORS INFLUENCING PHOSPHORUS EXCRETION BY HORSES

Excessive phosphorus (P) excreted by animals can affect water quality and cause eutrophication. Better understanding of factors that influence P utilization and excretion in horses may reduce the environmental impact of P. Two animal experiments were conducted that examined P excretion by horses. The efficacy of titanium dioxide as an external marker to calculate digestibility was studied concurrently with both animal experiments. Additionally, pasture P concentrations were evaluated over the growing season using near-infrared spectroscopy (NIRS). Experiment 1 examined P excretion by post-lactational mares fed a low P diet immediately prior to weaning compared to non-lactating controls fed an adequate P diet. Post-lactational mares excreted more P compared to controls. Experiment 2 compared P excretion in horses fed to lose, maintain, or gain weight. Horses fed to lose weight tended to excrete more fecal P compared to horses fed to gain weight and had increased markers of bone turnover. The efficacy of titanium dioxide for estimating fecal output from limited fecal grab samples was variable. Titanium dioxide may be useful in situations where many fecal samples are collected over 5 d, but may not be as accurate if one fecal grab sample is expected to be representative of fecal output. Experiment 3 focused on examining the changes in pasture mineral concentration over the season using NIRS. A discussion of how these results may inform equine P supplementation programs is included. Overall, the work in this dissertation suggests that factors that influence P excretion in the horse include the dietary availability of P, physiological status, and active weight change. These variables can be incorporated into feeding programs to meet horses’ needs more closely while minimizing P excretion in the environment

Some old movies become classics - a case study determining the scientific value of ROV inspection footage on a platform on Australia's North West Shelf

© 2018 Thomson, Fowler, Davis, Pattiaratchi and Booth. The global oil and gas industry holds a vast archive of Remotely Operated Vehicle (ROV) inspection footage potentially containing useful long-term data on marine biological communities. With the upcoming era of decommissioning of oil and gas structures, it is timely to assess the usefulness of this footage for researching these communities. We used ROV inspection footage to characterize the sessile invertebrates and fishes associated with the Goodwyn Alpha Production Platform (GWA) on the North West Shelf of Australia between depths of 10 and 125 m during 2006 and 2008. Depth was a major driver of invertebrate assemblages, most likely due to specific requirements such as light, and differences between years were most likely from the physical detachment of species by cyclones and internal waves. Phototrophic species were mostly limited to the upper 50 m of the platform, including the hard coral Pocillopora sp. and the soft corals Nephthea sp. and Scleronephthya sp. In contrast, heterotrophic species including sponges, anemones, bryozoans, hydroids, bivalves such as Lopha folium and the hard coral Tubastrea spp., were distributed across all depths. We observed 1791 fish from at least 10 families and 19 species, including commercial species such as crimson seaperch (Lutjanus erythropterus), red emperor (L. sebae), saddle-tailed seaperch (L. malabaricus), mangrove jack (L. argentimaculatus) and trevally (Caranx spp.). Fish density increased significantly with depth during 2008, from a mean of 23 fish/50 m2 between 10 and 25 m to 3373 fish/50 m2 at 125 m, where small unidentified baitfish were abundant. The highest densities of commercial species occurred between 25 and 75 m depth, suggesting that mid-depth platform sections had high habitat value, a consideration when selecting decommissioning options. The greatest difficulties using the video were the poor lighting and resolution that inhibited our ability to identify sessile species with high taxonomic precision. However, the footage was useful for evaluating high-level biodiversity of the platform, understanding how fish and invertebrate communities changed with depth and comprehending the dynamic nature of the invertebrate community over time. Understanding the habitat value of structures will be necessary for making environmentally sound decommissioning decisions in the future

Comorbidity, Physical Function, and Quality of Life in Older Adults with Acute Myeloid Leukemia

Purpose of review: To describe the pathology, impact of comorbidities, functional limitations, symptoms, and quality of life (QOL) related to treatment of acute myeloid leukemia (AML) in older adults. Recent findings: AML is a rare aggressive hematologic disease that occurs most often in older adults. The prognosis for older patients with AML is markedly worse due to genetic mutations and patient characteristics such as comorbidities and functional limitations. Patient characteristics may influence treatment decisions, as well as impact symptoms, functional ability, health-related outcomes and (QOL). Summary: As the population continues to age, the number of people diagnosed with AML is expected to increase. Better management of comorbidities is imperative to improving QOL and other treatment related outcomes. Prospective, longitudinal and multi-site studies are warranted to further understand the interaction between these characteristics on symptoms, outcomes and QOL

High threshold universal quantum computation on the surface code

We present a comprehensive and self-contained simplified review of the quantum computing scheme of Phys. Rev. Lett. 98, 190504 (2007), which features a 2-D nearest neighbor coupled lattice of qubits, a threshold error rate approaching 1%, natural asymmetric and adjustable strength error correction and low overhead arbitrarily long-range logical gates. These features make it by far the best and most practical quantum computing scheme devised to date. We restrict the discussion to direct manipulation of the surface code using the stabilizer formalism, both of which we also briefly review, to make the scheme accessible to a broad audience.Comment: 18 pages, 28 figures, state distillation section correcte

Trace Mineral Leaching from Equine Compost

Mineral leaching from compost can be environmentally disruptive. Little information is available regarding trace mineral leaching from equine-sourced compost. The objective of this study was to quantify the mineral content and leaching potential of compost produced from feces of horses fed different amounts and forms (organic or inorganic) of trace minerals. Nine horses were fed three treatments in a 3 × 3 replicated Latin Square design. The dietary treatments were provided as a daily pellet: CON (pellet without added trace minerals), ING (added inorganic trace minerals), and ORG (added organic trace minerals). The added trace minerals were Co, Cu, Mn, and Zn. Feces were collected from each horse after a 16-day feeding period, combined with straw, composted, and then subjected to simulated rainfall to measure mineral mobility. Concentrations of Co, Cu, Mn, and Zn were greater in ING and ORG compared to CON compost (p \u3c 0.05); additionally, ING had greater Zn than ORG compost (p \u3c 0.05). More Cu leached from ING and ORG compared to CON (p \u3c 0.05). The most Zn leached from ING, followed by ORG, and the least amount leached from CON compost (p \u3c 0.05). Dietary trace mineral intake affected the trace mineral concentration in the compost and amount available to leach during rainfall events

Some old movies become classics - a case study determining the scientific value of ROV inspection footage on a platform on Australia\u27s North West Shelf

The global oil and gas industry holds a vast archive of Remotely Operated Vehicle (ROV) inspection footage potentially containing useful long-term data on marine biological communities. With the upcoming era of decommissioning of oil and gas structures, it is timely to assess the usefulness of this footage for researching these communities. We used ROV inspection footage to characterize the sessile invertebrates and fishes associated with the Goodwyn Alpha Production Platform (GWA) on the North West Shelf of Australia between depths of 10 and 125 m during 2006 and 2008. Depth was a major driver of invertebrate assemblages, most likely due to specific requirements such as light, and differences between years were most likely from the physical detachment of species by cyclones and internal waves. Phototrophic species were mostly limited to the upper 50 m of the platform, including the hard coral Pocillopora sp. and the soft corals Nephthea sp. and Scleronephthya sp. In contrast, heterotrophic species including sponges, anemones, bryozoans, hydroids, bivalves such as Lopha folium and the hard coral Tubastrea spp., were distributed across all depths. We observed 1791 fish from at least 10 families and 19 species, including commercial species such as crimson seaperch (Lutjanus erythropterus), red emperor (L. sebae), saddle-tailed seaperch (L. malabaricus), mangrove jack (L. argentimaculatus) and trevally (Caranx spp.). Fish density increased significantly with depth during 2008, from a mean of 23 fish/50 m2 between 10 and 25 m to 3373 fish/50 m2 at 125 m, where small unidentified baitfish were abundant. The highest densities of commercial species occurred between 25 and 75 m depth, suggesting that mid-depth platform sections had high habitat value, a consideration when selecting decommissioning options. The greatest difficulties using the video were the poor lighting and resolution that inhibited our ability to identify sessile species with high taxonomic precision. However, the footage was useful for evaluating high-level biodiversity of the platform, understanding how fish and invertebrate communities changed with depth and comprehending the dynamic nature of the invertebrate community over time. Understanding the habitat value of structures will be necessary for making environmentally sound decommissioning decisions in the future

Long-term effects of allergen sensitization and exposure in adult asthma: a prospective study.

BACKGROUND: : We investigated the effects of sensitization and exposure to common domestic allergens on longitudinal changes in lung function and bronchial hyperresponsiveness. METHODS: : Subjects attended 2 visits that were 4 years apart. Skin prick testing was performed and household dust samples were collected for quantification of mite, dog, and cat allergens at baseline. Measurements of lung function, exhaled nitric oxide, and bronchial hyperresponsiveness were completed at both visits. RESULTS: : Dust samples were collected in 165 of the 200 subjects completing both visits. Mean length of follow-up was 47 months. Bronchial hyperresponsiveness, measured at both visits in 86 subjects, deteriorated in those exposed to high mite allergen levels compared with those not exposed [mean (95% CI) doubling dose change PD20 = -0.44 (-1.07 to 0.19) vs 0.82 (0.27 to 1.36)], but improved in those exposed to high dog allergen levels compared with those not exposed [1.10 (0.33 to 1.86) vs 0.10 (-0.39 to 0.58)]. The associations were significant in the multivariate models. Cat allergen exposure was not associated with any changes in lung function, exhaled nitric oxide, or bronchial hyperresponsiveness. CONCLUSIONS: : In a 4-year prospective cohort of persons with asthma, exposure to high levels of dust mite allergens at baseline was associated with a subsequent increase in bronchial hyperresponsiveness

Equity and Access: Empowering Change Agents

All learners must have access and opportunity to engage meaningfully in the highest levels of mathematics. Mathematics specialists are uniquely situated to contribute to the creation of access and equity for all learners by addressing three target areas with their mathematics teachers and administrators. In order to catalyze change, mathematics specialists need to be prepared to target three obstacles to access and equity: beliefs and expectations, curriculum and instruction, and intervention. This preparation can take place through leadership courses intentionally created to explore the role of change agent and provide practice in negotiating the role