2,799 research outputs found
Beyond "the Relationship between the Individual and Society": broadening and deepening relational thinking in group analysis
The question of âthe relationship between the individual and societyâ has troubled group analysis since its inception. This paper offers a reading of Foulkes that highlights the emergent, yet evanescent, psychosocial ontology in his writings, and argues for the development of a truly psychosocial group analysis, which moves beyond the individual/society dualism. It argues for a shift towards a language of relationality, and proposes new theoretical resources for such a move from relational sociology, relational psychoanalysis and the âmatrixial thinkingâ of Bracha Ettinger which would broaden and deepen group analytic understandings of relationality
Developmental stage-specific regulation of the circadian Clock by Temperature in Zebrafish
The circadian clock enables animals to adapt their physiology and behaviour in anticipation of the day-night cycle. Light and temperature represent two key environmental timing cues (zeitgebers) able to reset this mechanism and so maintain its synchronization with the environmental cycle. One key challenge is to unravel how the regulation of the clock by zeitgebers matures during early development. The zebrafish is an ideal model for studying circadian clock ontogeny since the process of development occurs ex utero in an optically transparent chorion and many tools are available for genetic analysis. However, the role played by temperature in regulating the clock during zebrafish development is poorly understood. Here, we have established a clock-regulated luciferase reporter transgenic zebrafish line (Tg (â3.1) per1b::luc) to study the effects of temperature on clock entrainment. We reveal that under complete darkness, from an early developmental stage onwards (48 to 72âhpf), exposure to temperature cycles is a prerequisite for the establishment of self-sustaining rhythms of zfper1b, zfaanat2, and zfirbp expression and also for circadian cell cycle rhythms. Furthermore, we show that following the 5â9 somite stage, the expression of zfper1b is regulated by acute temperature shifts
Accurate exchange-correlation energies for the warm dense electron gas
Density matrix quantum Monte Carlo (DMQMC) is used to sample exact-on-average
-body density matrices for uniform electron gas systems of up to 10
matrix elements via a stochastic solution of the Bloch equation. The results of
these calculations resolve a current debate over the accuracy of the data used
to parametrize finite-temperature density functionals. Exchange-correlation
energies calculated using the real-space restricted path-integral formalism and
the -space configuration path-integral formalism disagree by up to
\% at certain reduced temperatures and densities . Our calculations confirm the accuracy of the configuration
path-integral Monte Carlo results available at high density and bridge the gap
to lower densities, providing trustworthy data in the regime typical of
planetary interiors and solids subject to laser irradiation. We demonstrate
that DMQMC can calculate free energies directly and present exact free energies
for and .Comment: Accepted version: added free energy data and restructured text. Now
includes supplementary materia
The sign problem and population dynamics in the full configuration interaction quantum Monte Carlo method
The recently proposed full configuration interaction quantum Monte Carlo
method allows access to essentially exact ground-state energies of systems of
interacting fermions substantially larger than previously tractable without
knowledge of the nodal structure of the ground-state wave function. We
investigate the nature of the sign problem in this method and how its severity
depends on the system studied. We explain how cancelation of the positive and
negative particles sampling the wave function ensures convergence to a
stochastic representation of the many-fermion ground state and accounts for the
characteristic population dynamics observed in simulations.Comment: 11 pages. 6 figure
Open-source development experiences in scientific software: the HANDE quantum Monte Carlo project
The HANDE quantum Monte Carlo project offers accessible stochastic algorithms
for general use for scientists in the field of quantum chemistry. HANDE is an
ambitious and general high-performance code developed by a
geographically-dispersed team with a variety of backgrounds in computational
science. In the course of preparing a public, open-source release, we have
taken this opportunity to step back and look at what we have done and what we
hope to do in the future. We pay particular attention to development processes,
the approach taken to train students joining the project, and how a flat
hierarchical structure aids communicationComment: 6 pages. Submission to WSSSPE
Riding a Spiral Wave: Numerical Simulation of Spiral Waves in a Co-Moving Frame of Reference
We describe an approach to numerical simulation of spiral waves dynamics of
large spatial extent, using small computational grids.Comment: 15 pages, 14 figures, as accepted by Phys Rev E 2010/03/2
No association betweenP53codon 72 polymorphism and risk of squamous cell carcinoma of the head and neck
An initial report suggested that patients homozygous for the arginine allele at codon 72 ofP53were at increased risk for human papillomavirus (HPV)-related cervical cancer, but other groups have not confirmed this finding. Since approximately 18â36% of head and neck cancers are HPV-related, we examined the genotypic frequencies at that locus in 163 cases with squamous cell carcinoma of the head and neck (SCCHN) and 163 ethnically matched controls. We found no significant excess of arginine homozygotes in cases compared to controls (P= 0.50). No significant differences in allele frequencies were observed when the data were stratified by tobacco exposure or by cancer site. These findings suggest a limited role, if any, for thisP53polymorphism in SCCHN.© 2000 Cancer Research Campaig
The democratic origins of the term "group analysis": Karl Mannheim's "third way" for psychoanalysis and social science.
It is well known that Foulkes acknowledged Karl Mannheim as the
first to use the term âgroup analysisâ. However, Mannheimâs work is
otherwise not well known. This article examines the foundations of
Mannheimâs sociological interest in groups using the Frankfurt
School (1929â1933) as a start point through to the brief correspondence
of 1945 between Mannheim and Foulkes (previously
unpublished). It is argued that there is close conjunction between
Mannheimâs and Foulkesâs revision of clinical psychoanalysis along
sociological lines. Current renderings of the Frankfurt School
tradition pay almost exclusive attention to the American connection
(Herbert Marcuse, Eric Fromm, Theodor Adorno and Max Horkheimer)
overlooking the contribution of the English connection through
the work of Mannheim and Foulkes
Tolerance of septoria leaf blotch in winter wheat
For individual varieties, tolerance of septoria leaf blotch was quantified by the slope of the relationship between disease and yield. Variation in disease severity and the associated yield responses were provided across two sites and three seasons of field experiments. Slopes were fitted by residual maximum likelihood for two contrasting models: (i) a fixed-effects model, where no prior assumptions were made about the form of the variety slopes; and (ii) a random-effects model, where deviations in individual variety slopes away from the mean variety slope formed a normal random population with unknown variance. The analyses gave broadly similar results, but with some significant differences. The random model was considered more reliable for predicting variety performance. The effects of disease were quantified as symptom area and green canopy duration. Models of the relationship between symptom area and yield were site-specific. When site effects were not taken into account, these models had poor predictive precision. Models based on the canopy green area gave robust predictions of yield and were not site-specific. Differences in disease tolerance were detected in a comparison of 25 commercial winter wheat varieties. Tolerance was not detected directly through symptom measurements, but instead through measurements of canopy green area, which provides a measurement of the effects of disease that accounts for differences in canopy size across sites and seasons. The varieties showing greatest tolerance tended to have lower attainable yield than the intolerant varieties. Presence of the 1BL/1RS chromosome translocation, which has been reported to increase radiation use efficiency, appeared to be associated with intolerance
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