1,056 research outputs found

    Exploratory Measurements of the (3-He,n) Reaction at Medium Energies

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    This work was supported by the National Science Foundation Grant NSF PHY 81-14339 and by Indiana Universit

    An Updated Description of Heavy-Hadron Interactions in Geant-4

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    Exotic stable massive particles (SMP) are proposed in a number of scenarios of physics beyond the Standard Model. It is important that LHC experiments are able both to detect and extract the quantum numbers of any SMP with masses around the TeV scale. To do this, an understanding of the interactions of SMPs in matter is required. In this paper a Regge-based model of R-hadron scattering is extended and implemented in Geant-4. In addition, the implications of RR-hadron scattering for collider searches are discussed

    Dielectronic Recombination in He+ Ions

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    This research was sponsored by the National Science Foundation Grant NSF PHY-931478

    Fibulin-1 Is Increased in Asthma – A Novel Mediator of Airway Remodeling?

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    Background: The extracellular matrix is a dynamic and complex network of macromolecules responsible for maintaining and influencing cellular functions of the airway. The role of fibronectin, an extracellular matrix protein, is well documented in asthma. However, the expression and function of fibulin-1, a secreted glycoprotein which interacts with fibronectin, has not been reported. Fibulin-1 is widely expressed in basement membranes in many organs including the lung. There are four isoforms in humans (A-D) of which fibulin-1C and 1D predominate. The objective of this study was to study the expression of fibulin-1 in volunteers with and without asthma, and to examine its function in vitro. Methodology/Principal Findings: We used immunohistochemistry and dot-blots to examine fibulin-1 levels in bronchial biopsies, bronchoalveolar lavage fluid and serum. Real-time PCR for fibulin-1C and 1D, and ELISA and western blotting for fibulin-1 were used to study the levels in airway smooth muscle cells. The function of fibulin-1C was determined by assessing its role, using an antisense oligonucleotide, in cell proliferation, migration and wound healing. A murine model of airway hyperresponsiveness (AHR) was used to explore the biological significance of fibulin-1. Levels of fibulin-1 were significantly increased in the serum and bronchoalveolar lavage fluid of 21 asthmatics compared with 11 healthy volunteers. In addition fibulin-1 was increased in asthma derived airway smooth muscle cells and fibulin-1C contributed to the enhanced proliferation and wound repair in these cells. These features were reversed when fibulin-1C was suppressed using an antisense oligomer. In a mouse model of AHR, treatment with an AO inhibited the development of AHR to methacholine. Conclusions: Our data collectively suggest fibulin-1C may be worthy of further investigation as a target for airway remodeling in asthma

    Citizen Science 2.0 : Data Management Principles to Harness the Power of the Crowd

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    Citizen science refers to voluntary participation by the general public in scientific endeavors. Although citizen science has a long tradition, the rise of online communities and user-generated web content has the potential to greatly expand its scope and contributions. Citizens spread across a large area will collect more information than an individual researcher can. Because citizen scientists tend to make observations about areas they know well, data are likely to be very detailed. Although the potential for engaging citizen scientists is extensive, there are challenges as well. In this paper we consider one such challenge – creating an environment in which non-experts in a scientific domain can provide appropriate and accurate data regarding their observations. We describe the problem in the context of a research project that includes the development of a website to collect citizen-generated data on the distribution of plants and animals in a geographic region. We propose an approach that can improve the quantity and quality of data collected in such projects by organizing data using instance-based data structures. Potential implications of this approach are discussed and plans for future research to validate the design are described

    Experimental tests of slender reinforced concrete columns under combined axial load and lateral force

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    The use of high strength concrete (HSC) in columns has become more frequent since a substantial reduction of the cross-section is obtained, meaning that slenderness increases for the same axial load and length, producing higher second order effects. However, the experimental tests in the literature of reinforced concrete columns subjected to axial load and lateral force focus on shear span ratios, according to Eurocode 2 (2004), clause 5.6.3., (M/(V·h)) lower than 6.5. This gap in the literature limits technological development for the construction of these structural elements. This paper presents 44 experimental tests on reinforced concrete columns subjected to constant axial load and monotonic lateral force. The aim of this is to gain greater knowledge of the types of elements which will also be of use in calibrating the numerical models and validating the simplified methods. The test parameters are strength of concrete (normal- and high-strength concrete), shear span ratio, axial load level and longitudinal and transversal reinforcement ratios. The strength and deformation of the columns were studied, and an analysis of the simplified methods from Eurocode 2 (2004) and ACI-318 (2008) concluded that both are very conservative. © 2011 Elsevier Ltd.The authors wish to express their sincere gratitude to the Spanish Ministry of Science and Innovation for the help provided through project BIA2009-10207 and to the European Union for the financial support from Feder funds.Barrera Puerto, A.; Bonet Senach, JL.; Romero, ML.; Miguel Sosa, P. (2011). Experimental tests of slender reinforced concrete columns under combined axial load and lateral force. Engineering Structures. 33(12):3676-3689. https://doi.org/10.1016/j.engstruct.2011.08.003S36763689331

    What do young athletes implicitly understand about psychological skills?

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    One reason sport psychologists teach psychological skills is to enhance performance in sport; but the value of psychological skills for young athletes is questionable because of the qualitative and quantitative differences between children and adults in their understanding of abstract concepts such as mental skills. To teach these skills effectively to young athletes, sport psychologists need to appreciate what young athletes implicitly understand about such skills because maturational (e.g., cognitive, social) and environmental (e.g., coaches) factors can influence the progressive development of children and youth. In the present qualitative study, we explored young athletes’ (aged 10–15 years) understanding of four basic psychological skills: goal setting, mental imagery, self-talk, and relaxation. Young athletes (n = 118: 75 males and 43 females) completed an open-ended questionnaire to report their understanding of these four basic psychological skills. Compared with the older youth athletes, the younger youth athletes were less able to explain the meaning of each psychological skill. Goal setting and mental imagery were better understood than self-talk and relaxation. Based on these findings, sport psychologists should consider adapting interventions and psychoeducational programs to match young athletes’ age and developmental level

    Effective flexural stiffness of slender reinforced concrete columns under axial forces and biaxial bending

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    Most of the design codes (ACI-318-2008 and Euro Code-2-2004) propose the moment magnifier method in order to take into account the second order effect to design slender reinforced concrete columns. The accuracy of this method depends on the effective flexural stiffness of the column. This paper proposes a new equation to obtain the effective stiffness EI of slender reinforced concrete columns. The expression is valid for any shape of cross-section, subjected to combined axial loads and biaxial bending, both for short-time and sustained loads, normal and high strength concretes, but it is only suitable for columns with equal effective buckling lengths in the two principal bending planes. The new equation extends the proposed EI equation in the "Biaxial bending moment magnifier method" by Bonet et al. (2004) [6], which is valid only for rectangular sections. The method was compared with 613 experimental tests from the literature and a good degree of accuracy was obtained. It was also compared with the design codes ACI-318 (08) and EC-2 (2004) improving the precision. The method is capable to verify and design with sufficient accuracy slender reinforced concrete columns in practical engineering design applications. © 2010 Elsevier Ltd.The authors wish to express their sincere gratitude to the Spanish "Ministerio de Ciencia e Innovacion" for help provided through projects BIA2008-03734 and BIA2009-10207 and to the European Community with the Feder funds.Bonet Senach, JL.; Romero, ML.; Miguel Sosa, P. (2011). Effective flexural stiffness of slender reinforced concrete columns under axial forces and biaxial bending. Engineering Structures. 33:881-893. doi:10.1016/j.engstruct.2010.12.009S8818933

    Cosmological evolution of interacting dark energy in Lorentz violation

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    The cosmological evolution of an interacting scalar field model in which the scalar field interacts with dark matter, radiation, and baryon via Lorentz violation is investigated. We propose a model of interaction through the effective coupling βˉ\bar{\beta}. Using dynamical system analysis, we study the linear dynamics of an interacting model and show that the dynamics of critical points are completely controlled by two parameters. Some results can be mentioned as follows. Firstly, the sequence of radiation, the dark matter, and the scalar field dark energy exist and baryons are sub dominant. Secondly, the model also allows the possibility of having a universe in the phantom phase with constant potential. Thirdly, the effective gravitational constant varies with respect to time through βˉ\bar{\beta}. In particular, we consider a simple case where βˉ\bar{\beta} has a quadratic form and has a good agreement with the modified Λ\LambdaCDM and quintessence models. Finally, we also calculate the first post--Newtonian parameters for our model.Comment: 14 pages, published versio
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