437 research outputs found

    Book Reviews

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    Book reviews of: Armies of Deliverance: A New History of the Civil War By Elizabeth R. Varon. College Edition. (New York: Oxford University Press, 2021. Maps, acknowledgments, timeline, notes, suggested readings, glossary, index. Pp. xxv, 531. 29.99paper.ISBN:9780199335398.)HurtinWords:DebatingFamilyProblemsintheTwentiethCenturySouth.ByTedOwnby.(ChapelHill:TheUniversityofNorthCarolinaPress,2018.Acknowledgements,illustrations,notes,index.Pp.xiv,334.29.99 paper. ISBN: 978-0-19-933539-8.) Hurtin’ Words: Debating Family Problems in the Twentieth-Century South. By Ted Ownby. (Chapel Hill: The University of North Carolina Press, 2018. Acknowledgements, illustrations, notes, index. Pp. xiv, 334. 90 cloth, 29.95paper,29.95 paper, 22.99 electronic. ISBN: 978-1-46964-700-5.) Illusions of Emancipation: The Pursuit of Freedom & Equality in the Twilight of Slavery. By Joseph P. Reidy. (Chapel Hill: University of North Carolina Press, 2019. Acknowledgements, illustrations, map, notes, index. Pp. 1, 506. 39.95Hardcover,39.95 Hardcover, 29.99 E-Book. ISBN: 978-1-4696-4836-1.) Civil War Monuments and the Militarization of America. By Thomas J. Brown. (Chapel Hill: University of North Carolina Press, 2019. 384 pp., 6.125 x 9.25, 87 halftones, notes, bibl., index, Paper, 29.97,9781469653747.)ReconstructionPoliticsinaDeepSouthState:Alabama,18651874.ByWilliamWarrenRogers,Jr.(Tuscaloosa:UniversityofAlabamaPress,2021.Acknowledgments,illustrations,notes,bibliography.Pp.1,439.29.97, 978-1-4696-5374-7.) Reconstruction Politics in a Deep South State: Alabama, 1865–1874. By William Warren Rogers, Jr. (Tuscaloosa: University of Alabama Press, 2021. Acknowledgments, illustrations, notes, bibliography. Pp. 1, 439. 54.95 cloth. ISBN: 978-0817320744.) Fugitivism: Escaping Slavery in the Lower Mississippi Valley, 1820–1860. By S. Charles Bolton. (Fayetteville: The University of Arkansas Press, 2019. Acknowledgements, appendix, notes, index. Pp. x, 302. 34.95cloth.ISBN:9781682260099.)BernardodeGaˊlvez:SpanishHerooftheAmericanRevolution.ByGonzaloM.QuinteroSaravia.(ChapelHill:UniversityofNorthCarolinaPress,2018.Acknowledgements,appendix,notes,bibliography,index.Pp.xi,602,34.95 cloth. ISBN: 978-1-68226-009-9.) Bernardo de Gálvez: Spanish Hero of the American Revolution. By Gonzalo M. Quintero Saravia. (Chapel Hill: University of North Carolina Press, 2018. Acknowledgements, appendix, notes, bibliography, index. Pp. xi, 602, 38.00 cloth. ISBN: 9781469640792.

    RXTE-PCA observations of 1A 1118--61: timing and spectral studies during an outburst

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    We report detailed timing and spectral analysis of RXTE-PCA data obtained from observations during the outburst of a transient X-ray pulsar 1A 1118--61 in January 2009. The pulse profile showed significant evolution during the outburst and also significant energy dependence - a double peaked profile upto 10 keV and a single peak at higher energy. We have also detected quasi-periodic oscillations (QPO) at 0.07--0.09 Hz. The rms value of the QPO is 5.2% and it shows a significant energy dependence with highest rms of 7% at 9 keV. The QPO frequency changed from 0.09 Hz to 0.07 Hz within 10 days. The magnetic field strength calculated using the QPO frequency and the X-ray luminosity is in agreement with the magnetic field strength measured from the energy of the cyclotron absorption feature detected in this source. The 3-30 keV energy spectrum over the 2009 outburst of 1A 1118--61 can be well fitted with a partial covering power-law model with a high energy cutoff and an iron fluorescence line emission. The pulse phase resolved spectral analysis shows that the partial covering and high energy cutoff model parameters have significant changes with the pulse phase.Comment: Accepted for publication in MNRA

    Real-Time Measurements of Engine-Out Trace Elements: Application of a Novel Soot Particle Aerosol Mass Spectrometer for Emissions Characterization

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    Lubricant-derived trace element emissions are the largest contributors to the accumulation of incombustible ash in diesel particulate filters (DPF), eventually leading to filter plugging and an increase in engine fuel consumption. Particulate trace element emissions also pose adverse health effects and are the focus of increasingly stringent air quality regulations. To date, the rates and physical and chemical properties of lubricant-derived additive emissions are not well characterized, largely due to the difficulties associated with conducting the measurements. This work investigated the potential for conducting real-time measurements of lubricant-derived particle emissions. The experiment used the Soot Particle Aerosol Mass Spectrometer (SP-AMS) developed by Aerodyne Research to measure the size, mass and composition of submicron particles in the exhaust. Results confirm the ability of the SP-AMS to measure engine-out emissions of calcium, zinc, magnesium, phosphorous, and sulfur. Further, emissions of previously difficult to detect elements, such as boron, and low-level engine wear metals, such as lead, were also measured. This paper provides an overview of the results obtained with the SP-AMS, and demonstrates the utility of applying real-time techniques to engine-out and tailpipe-out trace element emissions. Application of the SP-AMS for engine exhaust characterization followed a two-part approach: (1) measurement validation, and (2) measurement of engine-out exhaust. Measurement validation utilized a diesel burner with precise control of lubricant consumption. Results showed a good correlation between CJ-4 oil consumption and measured levels of lubricant-derived trace elements in the particle phase. Following measurement validation, the SP-AMS measured engine-out emissions from a medium-duty diesel engine, operated over a standard speed/load matrix. This work demonstrates the utility of state-of-the-art online techniques (such as the SP-AMS) to measure engine-out emissions, including trace species derived from lubricant additives. Results help optimize the combined engine-lubricant-aftertreatment system and provide a real-time characterization of emissions. As regulations become more stringent and emission controls more complex, advanced measurement techniques with high sensitivity and fast time response will become an increasingly important part of engine characterization studies.United States. Environmental Protection Agency (Grant RD834560

    Cancer-related chronic pain

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    BACKGROUND: Disparities in cancer survival and pain rates negatively impact quality of life (QOL). This study examines cancer-related chronic pain (CP) and its impact on QOL in diverse cancer survivors. METHODS: This survey study focused on current and past pain, health, and QOL in black and white cancer survivors. Participants with breast, colorectal, lung, and prostate cancer and multiple myeloma were recruited through the Michigan State Cancer Registry. Analysis of variance was used to examine outcome differences by pain status, race, and sex. Hierarchical regressions explored predictors for experiencing pain. RESULTS: The subjects (N = 199) were 31% black, 49% female, and 57 to 79 years old; 19.5% experienced current pain, and 42.6% reported pain since diagnosis. Women experience more pain ( P < .001) and greater pain severity ( P = .04) than men. Blacks experienced more pain interference and disability ( P < .05). Experiencing pain is related to greater depressive symptoms, poorer functioning, and more symptoms. In hierarchical regressions, female sex predicted pain since diagnosis; pain severity for pain since diagnosis was predicted by black race and female sex. CONCLUSIONS: The authors extend the literature by showing that 20% of diverse cancer survivors had cancer-related CP, and 43% had experienced pain since diagnosis, revealing racial and sex disparities in cancer-related CP's incidence and impact on QOL. Having pain was related to poorer QOL in several domains and was more frequently experienced by women. Although black race was not related to pain prevalence, it was related to greater severity. This study reveals an unaddressed cancer survivorship research, clinical, and policy issue. Cancer 2011. © 2010 American Cancer Society.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/83753/1/25761_ftp.pd

    Mitochondrial ATP fuels ABC transporter-mediated drug efflux in cancer chemoresistance

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    Chemotherapy remains the standard of care for most cancers worldwide, however development of chemoresistance due to the presence of the drug-effluxing ATP binding cassette (ABC) transporters remains a significant problem. The development of safe and effective means to overcome chemoresistance is critical for achieving durable remissions in many cancer patients. We have investigated the energetic demands of ABC transporters in the context of the metabolic adaptations of chemoresistant cancer cells. Here we show that ABC transporters use mitochondrial-derived ATP as a source of energy to efflux drugs out of cancer cells. We further demonstrate that the loss of methylation-controlled J protein (MCJ) (also named DnaJC15), an endogenous negative regulator of mitochondrial respiration, in chemoresistant cancer cells boosts their ability to produce ATP from mitochondria and fuel ABC transporters. We have developed MCJ mimetics that can attenuate mitochondrial respiration and safely overcome chemoresistance in vitro and in vivo. Administration of MCJ mimetics in combination with standard chemotherapeutic drugs could therefore become an alternative strategy for treatment of multiple cancers

    Limits on WWZ and WW\gamma couplings from p\bar{p}\to e\nu jj X events at \sqrt{s} = 1.8 TeV

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    We present limits on anomalous WWZ and WW-gamma couplings from a search for WW and WZ production in p-bar p collisions at sqrt(s)=1.8 TeV. We use p-bar p -> e-nu jjX events recorded with the D0 detector at the Fermilab Tevatron Collider during the 1992-1995 run. The data sample corresponds to an integrated luminosity of 96.0+-5.1 pb^(-1). Assuming identical WWZ and WW-gamma coupling parameters, the 95% CL limits on the CP-conserving couplings are -0.33<lambda<0.36 (Delta-kappa=0) and -0.43<Delta-kappa<0.59 (lambda=0), for a form factor scale Lambda = 2.0 TeV. Limits based on other assumptions are also presented.Comment: 11 pages, 2 figures, 2 table

    Search For Heavy Pointlike Dirac Monopoles

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    We have searched for central production of a pair of photons with high transverse energies in ppˉp\bar p collisions at s=1.8\sqrt{s} = 1.8 TeV using 70pb170 pb^{-1} of data collected with the D\O detector at the Fermilab Tevatron in 1994--1996. If they exist, virtual heavy pointlike Dirac monopoles could rescatter pairs of nearly real photons into this final state via a box diagram. We observe no excess of events above background, and set lower 95% C.L. limits of 610,870,or1580GeV/c2610, 870, or 1580 GeV/c^2 on the mass of a spin 0, 1/2, or 1 Dirac monopole.Comment: 12 pages, 4 figure

    The Dijet Mass Spectrum and a Search for Quark Compositeness in bar{p}p Collisions at sqrt{s} = 1.8 TeV

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    Using the DZero detector at the 1.8 TeV pbarp Fermilab Tevatron collider, we have measured the inclusive dijet mass spectrum in the central pseudorapidity region |eta_jet| < 1.0 for dijet masses greater than 200 Gev/c^2. We have also measured the ratio of spectra sigma(|eta_jet| < 0.5)/sigma(0.5 < |eta_jet| < 1.0). The order alpha_s^3 QCD predictions are in good agreement with the data and we rule out models of quark compositeness with a contact interaction scale < 2.4 TeV at the 95% confidence level.Comment: 11 pages, 4 figures, 2 tables, submitted to Phys. Rev. Let

    Zgamma Production in pbarp Collisions at sqrt(s)=1.8 TeV and Limits on Anomalous ZZgamma and Zgammagamma Couplings

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    We present a study of Z +gamma + X production in p-bar p collisions at sqrt{S}=1.8 TeV from 97 (87) pb^{-1} of data collected in the eegamma (mumugamma) decay channel with the D0 detector at Fermilab. The event yield and kinematic characteristics are consistent with the Standard Model predictions. We obtain limits on anomalous ZZgamma and Zgammagamma couplings for form factor scales Lambda = 500 GeV and Lambda = 750 GeV. Combining this analysis with our previous results yields 95% CL limits |h{Z}_{30}| < 0.36, |h{Z}_{40}| < 0.05, |h{gamma}_{30}| < 0.37, and |h{gamma}_{40}| < 0.05 for a form factor scale Lambda=750 GeV.Comment: 17 Pages including 2 Figures. Submitted to PR

    Measurement of the WW Boson Mass

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    A measurement of the mass of the WW boson is presented based on a sample of 5982 WeνW \rightarrow e \nu decays observed in ppp\overline{p} collisions at s\sqrt{s} = 1.8~TeV with the D\O\ detector during the 1992--1993 run. From a fit to the transverse mass spectrum, combined with measurements of the ZZ boson mass, the WW boson mass is measured to be MW=80.350±0.140(stat.)±0.165(syst.)±0.160(scale)GeV/c2M_W = 80.350 \pm 0.140 (stat.) \pm 0.165 (syst.) \pm 0.160 (scale) GeV/c^2.Comment: 12 pages, LaTex, style Revtex, including 3 postscript figures (submitted to PRL
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