24,101 research outputs found
Quantum Inequalities on the Energy Density in Static Robertson-Walker Spacetimes
Quantum inequality restrictions on the stress-energy tensor for negative
energy are developed for three and four-dimensional static spacetimes. We
derive a general inequality in terms of a sum of mode functions which
constrains the magnitude and duration of negative energy seen by an observer at
rest in a static spacetime. This inequality is evaluated explicitly for a
minimally coupled scalar field in three and four-dimensional static
Robertson-Walker universes. In the limit of vanishing curvature, the flat
spacetime inequalities are recovered. More generally, these inequalities
contain the effects of spacetime curvature. In the limit of short sampling
times, they take the flat space form plus subdominant curvature-dependent
corrections.Comment: 18 pages, plain LATEX, with 3 figures, uses eps
Optimization of controlled environments for hydroponic production of leaf lettuce for human life support in CELSS
A research project in the food production group of the Closed Ecological Life Support System (CELSS) program sought to define optimum conditions for photosynthetic productivity of a higher plant food crop. The effects of radiation and various atmospheric compositions were studied
Stochastic Spacetime and Brownian Motion of Test Particles
The operational meaning of spacetime fluctuations is discussed. Classical
spacetime geometry can be viewed as encoding the relations between the motions
of test particles in the geometry. By analogy, quantum fluctuations of
spacetime geometry can be interpreted in terms of the fluctuations of these
motions. Thus one can give meaning to spacetime fluctuations in terms of
observables which describe the Brownian motion of test particles. We will first
discuss some electromagnetic analogies, where quantum fluctuations of the
electromagnetic field induce Brownian motion of test particles. We next discuss
several explicit examples of Brownian motion caused by a fluctuating
gravitational field. These examples include lightcone fluctuations, variations
in the flight times of photons through the fluctuating geometry, and
fluctuations in the expansion parameter given by a Langevin version of the
Raychaudhuri equation. The fluctuations in this parameter lead to variations in
the luminosity of sources. Other phenomena which can be linked to spacetime
fluctuations are spectral line broadening and angular blurring of distant
sources.Comment: 15 pages, 3 figures. Talk given at the 9th Peyresq workshop, June
200
Cosmological and Black Hole Horizon Fluctuations
The quantum fluctuations of horizons in Robertson-Walker universes and in the
Schwarzschild spacetime are discussed. The source of the metric fluctuations is
taken to be quantum linear perturbations of the gravitational field. Lightcone
fluctuations arise when the retarded Green's function for a massless field is
averaged over these metric fluctuations. This averaging replaces the
delta-function on the classical lightcone with a Gaussian function, the width
of which is a measure of the scale of the lightcone fluctuations. Horizon
fluctuations are taken to be measured in the frame of a geodesic observer
falling through the horizon. In the case of an expanding universe, this is a
comoving observer either entering or leaving the horizon of another observer.
In the black hole case, we take this observer to be one who falls freely from
rest at infinity. We find that cosmological horizon fluctuations are typically
characterized by the Planck length. However, black hole horizon fluctuations in
this model are much smaller than Planck dimensions for black holes whose mass
exceeds the Planck mass. Furthermore, we find black hole horizon fluctuations
which are sufficiently small as not to invalidate the semiclassical derivation
of the Hawking process.Comment: 22 pages, Latex, 4 figures, uses eps
Quantum Field Theory Constrains Traversable Wormhole Geometries
Recently a bound on negative energy densities in four-dimensional Minkowski
spacetime was derived for a minimally coupled, quantized, massless, scalar
field in an arbitrary quantum state. The bound has the form of an uncertainty
principle-type constraint on the magnitude and duration of the negative energy
density seen by a timelike geodesic observer. When spacetime is curved and/or
has boundaries, we argue that the bound should hold in regions small compared
to the minimum local characteristic radius of curvature or the distance to any
boundaries, since spacetime can be considered approximately Minkowski on these
scales. We apply the bound to the stress-energy of static traversable wormhole
spacetimes. Our analysis implies that either the wormhole must be only a little
larger than Planck size or that there is a large discrepancy in the length
scales which characterize the wormhole. In the latter case, the negative energy
must typically be concentrated in a thin band many orders of magnitude smaller
than the throat size. These results would seem to make the existence of
macroscopic traversable wormholes very improbable.Comment: 26 pages, plain LaTe
Quantum Inequalities and Singular Energy Densities
There has been much recent work on quantum inequalities to constrain negative
energy. These are uncertainty principle-type restrictions on the magnitude and
duration of negative energy densities or fluxes. We consider several examples
of apparent failures of the quantum inequalities, which involve passage of an
observer through regions where the negative energy density becomes singular. We
argue that this type of situation requires one to formulate quantum
inequalities using sampling functions with compact support. We discuss such
inequalities, and argue that they remain valid even in the presence of singular
energy densities.Comment: 18 pages, LaTex, 2 figures, uses eps
Relation Between Einstein And Quantum Field Equations
We show that there exists a choice of scalar field modes, such that the
evolution of the quantum field in the zero-mass and large-mass limits is
consistent with the Einstein equations for the background geometry. This choice
of modes is also consistent with zero production of these particles and thus
corresponds to a preferred vacuum state preserved by the evolution. In the
zero-mass limit, we find that the quantum field equation implies the Einstein
equation for the scale factor of a radiation-dominated universe; in the
large-mass case, it implies the corresponding Einstein equation for a
matter-dominated universe. Conversely, if the classical radiation-dominated or
matter-dominated Einstein equations hold, there is no production of scalar
particles in the zero and large mass limits, respectively. The suppression of
particle production in the large mass limit is over and above the expected
suppression at large mass. Our results hold for a certain class of conformally
ultrastatic background geometries and therefore generalize previous results by
one of us for spatially flat Robertson-Walker background geometries. In these
geometries, we find that the temporal part of the graviton equations reduces to
the temporal equation for a massless minimally coupled scalar field, and
therefore the results for massless particle production hold also for gravitons.
Within the class of modes we study, we also find that the requirement of zero
production of massless scalar particles is not consistent with a non-zero
cosmological constant. Possible implications are discussed.Comment: Latex, 24 pages. Minor changes in text from original versio
Energy Density-Flux Correlations in an Unusual Quantum State and in the Vacuum
In this paper we consider the question of the degree to which negative and
positive energy are intertwined. We examine in more detail a previously studied
quantum state of the massless minimally coupled scalar field, which we call a
``Helfer state''. This is a state in which the energy density can be made
arbitrarily negative over an arbitrarily large region of space, but only at one
instant in time. In the Helfer state, the negative energy density is
accompanied by rapidly time-varying energy fluxes. It is the latter feature
which allows the quantum inequalities, bounds which restrict the magnitude and
duration of negative energy, to hold for this class of states. An observer who
initially passes through the negative energy region will quickly encounter
fluxes of positive energy which subsequently enter the region. We examine in
detail the correlation between the energy density and flux in the Helfer state
in terms of their expectation values. We then study the correlation function
between energy density and flux in the Minkowski vacuum state, for a massless
minimally coupled scalar field in both two and four dimensions. In this latter
analysis we examine correlation functions rather than expectation values.
Remarkably, we see qualitatively similar behavior to that in the Helfer state.
More specifically, an initial negative energy vacuum fluctuation in some region
of space is correlated with a subsequent flux fluctuation of positive energy
into the region. We speculate that the mechanism which ensures that the quantum
inequalities hold in the Helfer state, as well as in other quantum states
associated with negative energy, is, at least in some sense, already
``encoded'' in the fluctuations of the vacuum.Comment: 21 pages, 7 figures; published version with typos corrected and one
added referenc
The averaged null energy condition and difference inequalities in quantum field theory
Recently, Larry Ford and Tom Roman have discovered that in a flat cylindrical
space, although the stress-energy tensor itself fails to satisfy the averaged
null energy condition (ANEC) along the (non-achronal) null geodesics, when the
``Casimir-vacuum" contribution is subtracted from the stress-energy the
resulting tensor does satisfy the ANEC inequality. Ford and Roman name this
class of constraints on the quantum stress-energy tensor ``difference
inequalities." Here I give a proof of the difference inequality for a minimally
coupled massless scalar field in an arbitrary two-dimensional spacetime, using
the same techniques as those we relied on to prove ANEC in an earlier paper
with Robert Wald. I begin with an overview of averaged energy conditions in
quantum field theory.Comment: 20 page
Are routinely collected NHS administrative records suitable for endpoint identification in clinical trials? Evidence from the West of Scotland coronary prevention study
Background: Routinely collected electronic patient records are already widely used in epidemiological research. In this work we investigated the potential for using them to identify endpoints in clinical trials.<p></p>
Methods: The events recorded in the West of Scotland Coronary Prevention Study (WOSCOPS), a large clinical trial of pravastatin in middle-aged hypercholesterolaemic men in the 1990s, were compared with those in the record-linked deaths and hospitalisations records routinely collected in Scotland.<p></p>
Results: We matched 99% of fatal study events by date. We showed excellent matching (97%) of the causes of fatal
endpoint events and good matching (.80% for first events) of the causes of nonfatal endpoint events with a slightly lower
rate of mismatching of record linkage than study events (19% of first study myocardial infarctions (MI) and 4% of first record linkage MIs not matched as MI). We also investigated the matching of non-endpoint events and showed a good level of matching, with .78% of first stroke/TIA events being matched as stroke/TIA. The primary reasons for mismatches were record linkage data recording readmissions for procedures or previous events, differences between the diagnoses in the routinely collected data and the conclusions of the clinical trial expert adjudication committee, events occurring outside Scotland and therefore being missed by record linkage data, miscoding of cardiac events in hospitalisations data as âunspecified chest painâ, some general miscoding in the record linkage data and some record linkage errors.<p></p>
Conclusions: We conclude that routinely collected data could be used for recording cardiovascular endpoints in clinical
trials and would give very similar results to rigorously collected clinical trial data, in countries with unified health systems such as Scotland. The endpoint types would need to be carefully thought through and an expert endpoint adjudication committee should be involved.<p></p>
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