Leontief and the Future of the World Economy

Along this document we have revised the experiences with world models and its performance to develop alternative forecast scenarios. Particularly, we have described with some details the Leontief’s world model, developed in 1979 and the main scenarios derived from that model. Finally, we propose a tentative research agenda with the aim of improve that successful experience with the aid of the most recent statistical developments.Forecast, World Economy;Input-Output Models

Linking cross-impact probabilistic scenarios to input-output models

Forecast, World Economy;Input-Output Models

Scenario Models of the World Economy

The purpose of this paper is threefold: First it discusses the case for building an IO-based model of the world economy, second, it discusses the type and the necessary characteristics of such a model and finally it highlights a road map for its construction. In the process it argues for the following set of propositions: a) the necessity of reviving the notion of world models b) the need to take on simultaneously the social-economic and environmental challenges and their interdependence c) the suitability of the IO framework as the basis of the next generation of world models d) the importance of bringing theory to bear on the development of the model and on policy analysis e) the importance of community for the development, support and diffusion of the model and its uses f) asserting the importance of the role of IIOA in building that community g) a focus on interdisciplinarity rather than on the export of economic logic alone to the social and environmental dimensions h) the importance of a scenario-based approach and i) the need to develop and integrate the financial side along with the real side of the economy.Forecast, World Economy;Input-Output Models

Precios relativos y estructuras de los mercados: diálogo fuera del tiempo con Luigi Solari

En el presente documento se recogen los planteamientos clásicos, en términos de modelos basados en tablas Input-output, del análisis de la influencia de las restricciones de producción y de consumo sobre las principales variables de un sistema económico, inicialmente en equilibrio. En el contexto de la política económica, se trata de estudiar las reestructuraciones de precio y de valor agregado impuestas por eventuales reducciones de la capacidad de producción de ciertos sectores. El documento concluye con una interpretación de la Nueva Economía desde las premisas básicas de este planteamiento.Input-Output Analisys; Consumption functions Systems; New Economy; Relative prices

Input-Output in Europe: Trends in Research and Application

Indubitably born in the USA, input-output analysis has an important European history, from its very beginnings in the Soviet Union to the postwar huge development of I/O techniques in West and North Europe. This paper studies the European experience of input-output analysis by surveying and analyzing some of the national experiences and especially the works in Great Britain of Richard Stone and his team. We show in particular how European economists have taken leadership in I/O research since the 1950s and more recently with the creation in 1989 of the journal of the International Input-Output Association, Economic System Research. In the latter European influence tends to focus works on theoretical and methodological issues more than empirical issues and applicationsInput-Output Analysis, Leontief, Stone, Applied economics, SAM, Computable General Equilibriun Models

CRISPR/Cas9 system and fluorescence enhanced BA-LIFT bioprinting technique as a toolbox for the study of the Immune System

Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Ciencias, Departamento de Biología Molecular. Fecha de lectura: 24-09-2020In this work, the CRISPR/Cas system genome editing toolbox and the fluorescence enhanced BA-LIFT laser bioprinting tools have been used to study the immune system cells behavior. CD69 is tightly regulated at the transcription level by the CNS2 regulatory region, whose epigenetic marks define as a bivalent regulatory element that match with the previously definition of CD69 as a bivalent gene. By CRISPR/Cas9 transcriptional assays and genome editing, two major areas within the CNS2 enhancer with antagonistic but complementary regulatory activities in vivo were defined in T cells: a Core E region of ~60 bp with a dual repressor and activator function; and a 5’ region adjacent to the Core E (5’C) of ~160 bp where the major activation transcriptional machinery is associated. Deletion of the Core E led to a CD69 overexpression both at resting and after stimulation, supporting its repressive role at steady state and avoiding CD69 overexpression upon stimulation. The Core E is enriched in the Oct1 and Chd4 TFs, whose bivalent function have been previously defined. RNA-seq analysis of ΔCore E T cells showed that CD69 overexpression is associated with an increase of the chemokine receptors CCR1, CCR2 and CCR5 at steady state, and of its ligands CCL3L3, CCL4 and CCL4L1 after stimulation, highlighting the role of CD69 in the regulation of chemokines and its receptors, as has been previously observed in mouse models. The role of the human ERAP2 aminopeptidase in the antigen presentation was assessed by generating a functional ERAP2 KO in B cells. Comparison of the HLA-B*27:05 ligandomes of ERAP+/+ and ERAP-/- cells determine that ERAP2 destroy ligands with N-terminal basic residues and peptides with minority anchor motifs at P2 (K and Q). A compensation effect in other peptide positions was observed, since the overall stability of the peptides remained constant. A newly developed fluorescence enhanced BA-LIFT laser bioprinting technique has been integrated. A laser-based bioprinting device for accurate identification, selection and printing of single or grouped cells within a complex population was developed and validated. FE BA-LIFT has proven to be an efficient and precise tool with high viability and resolution when depositing biological material in hydrogels or scaffolds with different characteristics. An IFN-γ human NK cell reporter has been generated by CRISPR/Cas9 to be used for the validation of the FE BA-LIFT bioprinte

Wh-relative clauses in English and their Spanish and German equivalents. A preliminary study

Traballo Fin de Grao en Lingua e Literatura Inglesas. Curso 2015-2016In this study I will investigate wh-relatives in English, Spanish and German, paying particular attention to the prepositional type, which has so far been relatively underexplored. Taking English wh-relatives as tertium comparationis (Kidd, 2011) and using a corpus-based methodology, this paper will describe whatever parallelisms and divergences emerge when comparing these constructions with their equivalents in Spanish (Bosque et al., 1999: 395-522; Mackenzie and Martínez Caro, 2012) and German (Lehmann, 1984; Krenn & Volk, 1993). Part 1 presents an overview of wh-relative clauses in English, Spanish and German, offering a revision of the relevant theoretical notions. Part 2, on the other hand, offers an empirical analysis based on the tokens of wh-relative clauses found in my corpus. Chapter 3 provides a description of the corpus on which this investigation is based: the Simon Fraser University review corpus (SFURC

Las relaciones entre los valores y principios cooperativos y los principios de la normativa cooperativa

Este trabajo propone un marco conceptual para entender las relaciones entre valores y principios cooperativos, por un lado, y también entre estos y los principios jurídicos de la normativa cooperativa. La Declaración Sobre la Identidad Cooperativa permite vislumbrar la postura de la Alianza Cooperativa Internacional sobre los valores. Los valores que proclama son valores éticos concebidos desde una postura utilitarista en la que los principios cooperativos son guías de conducta para la consecución de tales valores. Estos valores y principios éticos se relacionan con la normativa cooperativa a través de los principios jurídicos. Cuando son reconocidos en normas, los principios cooperativos generan principios jurídicos explícitos. Cuando son reconocidos por jueces, se reconocen como principios jurídicos implícitos. Sin embargo, ambas categorías presentan ciertos problemas de interpretación y alcance de sus mandatos que los diferencian de los principios cooperativos contemplados desde el plano ético

Quality of Air Sensors Emulator

Quality of Air Emulator descriptio