Double di ffential fragmentation cross sections measurements of 95 MeV/u 12C on thin targets for hadrontherapy

During therapeutic treatment with heavy ions like carbon, the beam undergoes nuclear fragmentation and secondary light charged particles, in particular protons and alpha particles, are produced. To estimate the dose deposited into the tumors and the surrounding healthy tissues, an accurate prediction on the fluences of these secondary fragments is necessary. Nowadays, a very limited set of double di ffential carbon fragmentation cross sections are being measured in the energy range used in hadrontherapy (40 to 400 MeV/u). Therefore, new measurements are performed to determine the double di ffential cross section of carbon on di erent thin targets. This work describes the experimental results of an experiment performed on May 2011 at GANIL. The double di ffential cross sections and the angular distributions of secondary fragments produced in the 12C fragmentation at 95 MeV/u on thin targets (C, CH2, Al, Al2O3, Ti and PMMA) have been measured. The experimental setup will be precisely described, the systematic error study will be explained and all the experimental data will be presented.Comment: Submitted to PR

Análise de custos da assistência à saúde aos portadores de diabetes melito e hipertensão arterial em uma unidade de saúde pública de referência em Recife - Brasil = Analysis of health care costs of patients with diabetes mellitus and hypertension in a public health reference unit in Recife - Brazil

Objective: To analyze health care costs of patients with diabetes mellitus and hypertension, and to estimate the cost of medium complexity outpatient procedures, compared with the standard reimbursement values used in Brazil. Materials and methods: We analyzed direct health costs in a public health reference unit in Recife/PE, in 2007. Costs were determined and allocated using the techniques of absorption costing and apportionment. Results: Direct costs and the amount reimbursed by the SUS totaled R$4,855,291.82 and R$ 2.118.893,56, respectively. The greatest groups of expenditure were medications, with R$1,762,424.42 (36.3$ 996,637.82 (20.5%); and personnel, with R$ 978,096.10 (20.1%). All procedures had higher estimated costs than what is reimbursed by the SUS. Conclusions: Drugs were associated with the highest health care costs, a considerable difference was observed between estimated costs and the amount reimbursed by the SUS. Arq Bras Endocrinol Metab. 2011;55(6):406-1

Monitoring Of 14 Mev Neutrons

Long-lived fission products and minor actinides produced in nuclear power plants are the most radiotoxic nuclear wastes. They can be transmuted into stable nuclei or into nuclei with shorter lifetime thanks to the so-called Accelerator Driven Systems (ADS), consisting of the coupling of an intense high energy proton beam, a spallation target and a sub-critical reactor core. For safety reasons, an on-line and robust measurement of the reactivity during loading and power operation is mandatory. The investigation of the relationship between the current of the accelerator and the power level (or neutron flux) of the reactor appears to be powerful, any change in reactivity being accessible through the measurement of the current and the flux. Such a relationship will be studied in an experiment to be performed at the YALINA facility (JIPNR Sosny - Belarus) in the framework of the EUROTRANS IP (6$^{th}$ FP). At this installation, 14 MeV neutrons are produced in T(d,n)$^{4}$He reactions by a deuteron beam impinging on a TiT target. Due to the tritium consumption over time, the intensity of the deuteron beam cannot be used for the monitoring of the neutron beam. The source neutron yield itself has to be accessed. This contribution describes the performance of a three-element silicon telescope dedicate

Comparison of two analysis methods for nuclear reaction measurements of 12C +12C interactions at 95 MeV/u for hadrontherapy

During therapeutic treatment with heavier ions like carbon, the beam undergoes nuclear fragmentation and secondary light charged particles, in particular protons and alpha particles, are produced. To estimate the dose deposited into the tumors and the surrounding healthy tissues, the accuracy must be higher than ($\pm$3% and$\pm$1 mm). Therefore, measurements are performed to determine the double differential cross section for different reactions. In this paper, the analysis of data from 12C +12C reactions at 95 MeV/u are presented. The emitted particles are detected with \DeltaEthin-\DeltaEthick-E telescopes made of a stack of two silicon detectors and a CsI crystal. Two different methods are used to identify the particles. One is based on graphical cuts onto the \DeltaE-E maps, the second is based on the so-called KaliVeda method using a functional description of \DeltaE versus E. The results of the two methods will be presented in this paper as well as the comparison between both

12C nuclear reaction measurements for hadrontherapy

International audienceHadrontherapy treatments require a very high precision on the dose deposition ( 2.5% and 1-2mm) in order to keep the benefits of the precise ions' ballistic. The largest uncertainty on the physical dose deposition is due to ion fragmentation. Up to now, the simulation codes are not able to reproduce the fragmentation process with the required precision. To constraint the nuclear models and complete fragmentation cross sections databases; our collaboration has performed an experiment on May 2008 at GANIL with a 95 MeV/u 12C beam. We have measured the fluence, energy and angular distributions of charged fragments and neutrons coming from nuclear reactions of incident 12C on thick water-like PMMA targets. Preliminary comparisons between GEANT4 (G4BinaryLightIonReaction) simulations and experimental data show huge discrepancies

Risk factor control in hypertensive and diabetic subjects attended by the Family Health Strategy in the State of Pernambuco, Brazil : the SERVIDIAH study = Controle dos fatores de risco em hipertensos e diabéticos acompanhados pela Estratégia Saúde da Família no Estado de Pernambuco, Brasil : estudo SERVIDIAH

The SERVIDIAH study (Evaluation of Health Services for Diabetic and Hypertensive Subjects) was conducted in 2010 in the State of Pernambuco, Brazil. A multi-stage random sample of 785 hypertensive and 823 diabetic patients was drawn from 208 Family Health Strategy (FHS) units selected throughout 35 municipalities. Patients underwent a structured interview and weight, height, blood pressure and HbA1c levels (for diabetic patients) were measured. Mean age was approximately 60 years, and women were overrepresented in the sample (70%). 43.7% of hypertensive subjects and 25.8% of diabetic subjects achieved adequate blood pressure control and 30.5% of diabetic subjects had HbA1c levels below 7%. Despite 70% of the patients being overweight or obese, few had adhered to a weight-loss diet. The study of this representative sample of hypertensive and diabetic patients attended by the FHS in the State of Pernambuco shows that improvements in the management of hypertension and diabetes are needed in order to prevent the occurrence of serious and costly complications, especially given the context of increasing incidence of these two conditions

A hybrid radiation detector for simultaneous spatial and temporal dosimetry

In this feasibility study an organic plastic scintillator is calibrated against ionisation chamber measurements and then embedded in a polymer gel dosimeter to obtain a quasi-4D experimental measurement of a radiation field. This hybrid dosimeter was irradiated with a linear accelerator, with temporal measurements of the dose rate being acquired by the scintillator and spatial measurements acquired with the gel dosimeter. The detectors employed in this work are radiologically equivalent; and we show that neither detector perturbs the intensity of the radiation field of the other. By employing these detectors in concert, spatial and temporal variations in the radiation intensity can now be detected and gel dosimeters can be calibrated for absolute dose from a single irradiation