21,515 research outputs found
Multiobjective analysis for the design and control of an electromagnetic valve actuator
The electromagnetic valve actuator can deliver much improved fuel efficiency and reduced emissions in spark ignition (SI) engines owing to the potential for variable valve timing when compared with cam-operated, or conventional, variable valve strategies. The possibility exists to reduce pumping losses by throttle-free operation, along with closed-valve engine braking. However, further development is required to make the technology suitable for accept- ance into the mass production market. This paper investigates the application of multiobjective optimization techniques to the conflicting objective functions inherent in the operation of such a device. The techniques are utilized to derive the optimal force–displacement characteristic for the solenoid actuator, along with its controllability and dynamic/steady state performance
Is it possible to accommodate massive photons in the framework of a gauge-invariant electrodynamics?
The construction of an alternative electromagnetic theory that preserves
Lorentz and gauge symmetries, is considered. We start off by building up
Maxwell electrodynamics in (3+1)D from the assumption that the associated
Lagrangian is a gauge-invariant functional that depends on the electron and
photon fields and their first derivatives only. In this scenario, as
well-known, it is not possible to set up a Lorentz invariant gauge theory
containing a massive photon. We show nevertheless that there exist two
radically different electrodynamics, namely, the Chern-Simons and the Podolsky
formulations, in which this problem can be overcome. The former is only valid
in odd space-time dimensions, while the latter requires the presence of
higher-order derivatives of the gauge field in the Lagrangian. This theory,
usually known as Podolsky electrodynamics, is simultaneously gauge and Lorentz
invariant; in addition, it contains a massive photon. Therefore, a massive
photon, unlike the popular belief, can be adequately accommodated within the
context of a gauge-invariant electrodynamics.Comment: 10 page
Impact of knee marker misplacement on gait kinematics of children with cerebral palsy using the Conventional Gait Model — a sensitivity study
Clinical gait analysis is widely used in clinical routine to assess the function of patients with motor disorders. The proper assessment of the patient’s function relies greatly on the repeatability between the measurements. Marker misplacement has been reported as the largest source of variability between measurements and its impact on kinematics is not fully understood. Thus, the purpose of this study was: 1) to evaluate the impact of the misplacement of the lateral femoral epicondyle marker on lower limb kinematics, and 2) evaluate if such impact can be predicted. The kinematic data of 10 children with cerebral palsy and 10 aged-match typical developing children were included. The lateral femoral epicondyle marker was virtually misplaced around its measured position at different magnitudes and directions. The outcome to represent the impact of each marker misplacement on the lower limb was the root mean square deviations between the resultant kinematics from each simulated misplacement and the originally calculated kinematics. Correlation and regression equations were estimated between the root mean square deviation and the magnitude of the misplacement expressed in percentage of leg length. Results indicated that the lower-limb kinematics is highly sensitive to the lateral femoral epicondyle marker misplacement in the anterior-posterior direction. The joint angles most impacted by the anterior-posterior misplacement were the hip internal-external rotation (5.3° per 10 mm), the ankle internal-external rotation (4.4° per 10 mm) and the knee flexion-extension (4.2° per 10 mm). Finally, it was observed that the lower the leg length, the higher the impact of misplacement on kinematics. This impact was predicted by regression equations using the magnitude of misplacement expressed in percentage of leg length. An error below 5° on all joints requires a marker placement repeatability under 1.2% of the leg length. In conclusion, the placement of the lateral femoral epicondyle marker in the antero-posterior direction plays a crucial role on the reliability of gait measurements with the Conventional Gait Model
Impacts of in vivo and in vitro exposures to tamoxifen: comparative effects on human cells and marine organisms
Tamoxifen (TAM) is a first generation-SERM administered for hormone receptor-positive (HER+) breast cancer in both pre- and post-menopausal patients and may undergo metabolic activation in organisms that share similar receptors and thus face comparable mechanisms of response. The present study aimed to assess whether environmental trace concentrations of TAM are bioavailable to the filter feeder M. galloprovincialis (100 ng L-1) and to the deposit feeder N. diversicolor (0.5, 10, 25 and 100 ng L-1) after 14 days of exposure. Behavioural impairment (burrowing kinetic), neurotoxicity (AChE activity), endocrine disruption by alkali-labile phosphate (ALP) content, oxidative stress (SOD, CAT, GPXs activities), biotransformation (GST activity), oxidative damage (LPO) and genotoxicity (DNA damage) were assessed. Moreover, this study also pertained to compare TAM cytotoxicity effects to mussels and targeted human (i.e. immortalized retinal pigment epithelium - RPE; and human transformed endothelial cells - HeLa) cell lines, in a range of concentrations from 0.5 ng L-1 to 50 μg L-1. In polychaetes N. diversicolor, TAM exerted remarkable oxidative stress and damage at the lowest concentration (0.5 ng L-1), whereas significant genotoxicity was reported at the highest exposure level (100 ng L-1). In mussels M. galloprovincialis, 100 ng L-1 TAM caused endocrine disruption in males, neurotoxicity, and an induction in GST activity and LPO byproducts in gills, corroborating in genotoxicity over the exposure days. Although cytotoxicity assays conducted with mussel haemocytes following in vivo exposure was not effective, in vitro exposure showed to be a feasible alternative, with comparable sensitivity to human cell line (HeLa).info:eu-repo/semantics/publishedVersio
Very High Mach Number Electrostatic Shocks in Collisionless Plasmas
The kinetic theory of collisionless electrostatic shocks resulting from the
collision of plasma slabs with different temperatures and densities is
presented. The theoretical results are confirmed by self-consistent
particle-in-cell simulations, revealing the formation and stable propagation of
electrostatic shocks with very high Mach numbers (), well above the
predictions of the classical theories for electrostatic shocks.Comment: 6 pages, submitted to Phys. Rev. Let
Beam loading in the nonlinear regime of plasma-based acceleration
A theory that describes how to load negative charge into a nonlinear,
three-dimensional plasma wakefield is presented. In this regime, a laser or an
electron beam blows out the plasma electrons and creates a nearly spherical ion
channel, which is modified by the presence of the beam load. Analytical
solutions for the fields and the shape of the ion channel are derived. It is
shown that very high beam-loading efficiency can be achieved, while the energy
spread of the bunch is conserved. The theoretical results are verified with the
Particle-In-Cell code OSIRIS.Comment: 5 pages, 2 figures, to appear in Physical Review Letter
A global simulation for laser driven MeV electrons in -diameter fast ignition targets
The results from 2.5-dimensional Particle-in-Cell simulations for the
interaction of a picosecond-long ignition laser pulse with a plasma pellet of
50- diameter and 40 critical density are presented. The high density
pellet is surrounded by an underdense corona and is isolated by a vacuum region
from the simulation box boundary. The laser pulse is shown to filament and
create density channels on the laser-plasma interface. The density channels
increase the laser absorption efficiency and help generate an energetic
electron distribution with a large angular spread. The combined distribution of
the forward-going energetic electrons and the induced return electrons is
marginally unstable to the current filament instability. The ions play an
important role in neutralizing the space charges induced by the the temperature
disparity between different electron groups. No global coalescing of the
current filaments resulted from the instability is observed, consistent with
the observed large angular spread of the energetic electrons.Comment: 9 pages, 6 figures, to appear in Physics of Plasmas (May 2006
Topological insulator particles as optically induced oscillators: towards dynamical force measurements and optical rheology
We report the first experimental study upon the optical trapping and
manipulation of topological insulator (TI) particles. By virtue of the unique
TI properties, which have a conducting surface and an insulating bulk, the
particles present a peculiar behaviour in the presence of a single laser beam
optical tweezers: they oscillate in a plane perpendicular to the direction of
the laser propagation, as a result of the competition between radiation
pressure and gradient forces. In other words, TI particles behave as optically
induced oscillators, allowing dynamical measurements with unprecedented
simplicity and purely optical control. Actually, optical rheology of soft
matter interfaces and biological membranes, as well as dynamical force
measurements in macromolecules and biopolymers, may be quoted as feasible
possibilities for the near future.Comment: 6 pages, 5 figures. Correspondence and requests for Supplementary
Material should be addressed to [email protected]
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