A Quarter-Century of Normalization and Social Role Valorization

During the late 1960s, Normalization and Social Role Valorization (SRV) enabled the widespread emergence of community residential options and then provided the philosophical climate within which educational integration, supported employment, and community participation were able to take firm root. This book is unique in tracing the evolution and impact of Normalization and SRV over the last quarter-century, with many of the chapter authors personally involved in a still-evolving international movement

A Quarter-Century of Normalization and Social Role Valorization

During the late 1960s, Normalization and Social Role Valorization (SRV) enabled the widespread emergence of community residential options and then provided the philosophical climate within which educational integration, supported employment, and community participation were able to take firm root. This book is unique in tracing the evolution and impact of Normalization and SRV over the last quarter-century, with many of the chapter authors personally involved in a still-evolving international movement

A new species of treehopper in the genus Cladonota Stål (Hemiptera: Membracidae: Membracinae: Hypsoprorini) from Costa Rica, with preliminary observations of its behaviour and natural history

England, Sam J., Flynn, Dawn J., Robert, Daniel (2020): A new species of treehopper in the genus Cladonota Stål (Hemiptera: Membracidae Membracinae: Hypsoprorini) from Costa Rica, with preliminary observations of its behaviour and natural history. Zootaxa 4750 (4): 596-598, DOI: https://doi.org/10.11646/zootaxa.4750.4.1

Levels of developmental assets and educational outcomes in young people in transitional living in Canada

"Developmental assets may be defined as significant relationships, skills, opportunities or values that protect young people in the presence of risk and promote their resilience. The purpose of this study was to discover whether high, medium, and low levels of developmental assets among transition-age young people in care were related to selected educational outcomes. If so, child welfare staff could potentially use their knowledge of a youth's level of assets to plan an appropriate level of educational assistance that would enable the youth to be more successful in his or her transition. The sample was composed of 567 young people (322 females and 245 males), aged 18-20 years, who were residing in a transitional living program in Ontario, Canada. The three levels of developmental assets were found to have statistically significant relationships with the seven educational outcomes examined that ranged between small-to-medium and strong in size. The educational outcomes consisted of the educational level in which the youth was currently enrolled, the highest educational level attained, average marks in school, participation in volunteering, employment, education or training, development of skills useful for employment, and adequacy of planning for the youth's education. The implications of the findings for rendering educational assistance to youths in particular need were discussed." (author's abstract)"Entwicklungsressourcen können als signifikante Beziehungen, Fähigkeiten, Chancen und Werte bestimmt werden, die Jugendliche in Risikolagen schützen und ihre Belastbarkeit fördern. Im Mittelpunkt der vorliegenden Studie stand die Frage, ob hohe, mittlere und niedrige Entwicklungsressourcenniveaus betreuter Jugendlicher in der Übergangsphase mit ausgewählten Bildungserfolgen in Zusammenhang stehen. Ist dies der Fall, könnten Fachkräfte ihr Wissen um die Entwicklungsressourcen von Jugendlichen nutzen, um eine angemessene pädagogische Begleitung zu planen, die Jugendlichen hilft, den Übergang erfolgreicher zu gestalten. Die Stichprobe der Studie setzte sich aus 567 jungen Menschen (322 Mädchen und 245 Jungen) im Alter von 18-20 Jahren zusammen, die ein Übergangsprogramm in Ontario (Kanada) durchliefen. Die Ergebnisse der Untersuchung zeigen, dass die drei Niveaus in unterschiedlicher Stärke statistisch signifikant mit Erfolgen in den sieben untersuchten Bildungsbereichen korrelieren. Diese umfassten den momentan angestrebten Bildungsabschluss, den höchsten bereits erreichten Bildungsabschluss, den Notendurchschnitt in der Schule, Partizipation in freiwilligen Engagements, Arbeit/ Beschäftigung, Bildung oder Training, die Entwicklung beschäftigungsrelevanter Fähigkeiten, sowie zukunftsorientierte Bildungspläne. Abschließend werden Folgerungen für die Begleitung von Jugendlichen mit spezifischen Bedürfnissen diskutiert." (Autorenreferat

Contaminate Control Device

A contaminate control device for filtering contaminates from a gas such as air is provided. The device includes a housing having a first inlet and a first outlet. An axial flow filter is fluidly coupled between the first inlet and the first outlet, the axial flow filter has a second inlet and a second outlet. A second filter disposed about the axial flow filter and is fluidly coupled between the first inlet and the first outlet, the second filter having a third inlet on an inner diameter and a third outlet disposed on an outer diameter. A flow restrictor is fluidly coupled between the second inlet and the first inlet

Anatomical and molecular properties of long descending propriospinal neurons in mice

Long descending propriospinal neurons (LDPNs) are interneurons that form direct connections between cervical and lumbar spinal circuits. LDPNs are involved in interlimb coordination and are important mediators of functional recovery after spinal cord injury (SCI). Much of what we know about LDPNs comes from a range of species, however, the increased use of transgenic mouse lines to better define neuronal populations calls for a more complete characterisation of LDPNs in mice. In this study, we examined the cell body location, inhibitory neurotransmitter phenotype, developmental provenance, morphology and synaptic inputs of mouse LDPNs throughout the cervical and upper thoracic spinal cord. LDPNs were retrogradely labelled from the lumbar spinal cord to map cell body locations throughout the cervical and upper thoracic segments. Ipsilateral LDPNs were distributed throughout the dorsal, intermediate and ventral grey matter as well as the lateral spinal nucleus and lateral cervical nucleus. In contrast, contralateral LDPNs were more densely concentrated in the ventromedial grey matter. Retrograde labelling in GlyT2GFP and GAD67GFP mice showed the majority of inhibitory LDPNs project either ipsilaterally or adjacent to the midline. Additionally, we used several transgenic mouse lines to define the developmental provenance of LDPNs and found that V2b positive neurons form a subset of ipsilaterally projecting LDPNs. Finally, a population of Neurobiotin (NB) labelled LDPNs were assessed in detail to examine morphology and plot the spatial distribution of contacts from a variety of neurochemically distinct axon terminals. These results provide important baseline data in mice for future work on their role in locomotion and recovery from SCI

Evaluation of “Dream Herb,” Calea zacatechichi

A recent surge in the use of dietary supplements, including herbal remedies, necessitates investigations into their safety profiles. “Dream herb,” Calea zacatechichi, has long been used in traditional folk medicine for a variety of purposes and is currently being marketed in the US for medicinal purposes, including diabetes treatment. Despite the inherent vulnerability of the renal system to xenobiotic toxicity, there is a lack of safety studies on the nephrotoxic potential of this herb. Additionally, the high frequency of diabetes-associated kidney disease makes safety screening of C. zacatechichi for safety especially important. We exposed human proximal tubule HK-2 cells to increasing doses of this herb alongside known toxicant and protectant control compounds to examine potential toxicity effects of C. zacatechichi relative to control compounds. We evaluated both cellular and mitochondrial functional changes related to toxicity of this dietary supplement and found that even at low doses evidence of cellular toxicity was significant. Moreover, these findings correlated with significantly elevated levels of nephrotoxicity biomarkers, lending further support for the need to further scrutinize the safety of this herbal dietary supplement