3,063 research outputs found

    Effect of the Ozonization Degree of Emu Oil over Healing: An Emerging Oxidation Treatment

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    This chapter deals with the ozonization process of the emu oil, the objective of this study was to quantitatively determine the peroxide value (PV) to measure the degree of ozonation, the peroxide value measures the number of peroxide groups in the ozonized oil. The ozone oxidizes the unsaturated chemical functions present in the oil giving a high cure rate for epidermal wounds. The healing process is not completely understood and there are different approaches, therefore, it was determined qualitatively if it has healing and inflammation properties, but the results of our studies have shown that the length and width of the wounds were healing quickly thanks to the peroxidation rate of the oils. In addition, both tests were correlated to obtain a greater appreciation of their functions, the mechanism involves a decrease in the inflammation of the wounds and stimulates the process of scar formation

    A marine chlamydomonas sp. emerging as an algal model

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    The freshwater microalga Chlamydomonas reinhardtii , which lives in wet soil, has served for decades as a model for numerous biological processes, and many tools have been introduced for this organism. Here, we have established a stable nuclear transformation for its marine counterpart, Chlamydomonas sp. SAG25.89, by fusing specific cis ‐acting elements from its Actin gene with the gene providing hygromycin resistance and using an elaborated electroporation protocol. Like C. reinhardtii , Chlamydomonas sp. has a high GC content, allowing reporter genes and selection markers to be applicable in both organisms. Chlamydomonas sp. grows purely photoautotrophically and requires ammonia as a nitrogen source because its nuclear genome lacks some of the genes required for nitrogen metabolism. Interestingly, it can grow well under both low and very high salinities (up to 50 g · L ‐1 ) rendering it as a model for osmotolerance. We further show that Chlamydomonas sp. grows well from 15 to 28°C, but halts its growth at 32°C. The genome of Chlamydomonas sp. contains some gene homologs the expression of which is regulated according to the ambient temperatures and/or confer thermal acclimation in C. reinhardtii . Thus, knowledge of temperature acclimation can now be compared to the marine species. Furthermore, Chlamydomonas sp. can serve as a model for studying marine microbial interactions and for comparing mechanisms in freshwater and marine environments. Chlamydomonas sp. was previously shown to be immobilized rapidly by a cyclic lipopeptide secreted from the antagonistic bacterium Pseudomonas protegens PF‐5, which deflagellates C. reinhardtii

    Intravenous single dose of tranexamic acid safely reduces blood loss and the need for transfusion in elderly patients with hip fracture. A randomized double-blinded controlled trial at 1-year follow-up

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    Background: A hip fracture usually presents significant blood loss in the perioperative period, with a transfusion rate of 20-60%. In order to reduce the complications associated with this procedure, the administration of Tranexamic Acid (TXA) has been implemented in the treatment of perioperative anemia. The objectives were to evaluate the effectiveness and safety of a single dose of intravenous Tranexamic Acid (TXA) in reducing perioperative blood loss and the requirement for transfusion in elderly patients undergoing hip fracture surgery within one postoperative year. Methods: A double-blind randomized controlled trial was conducted on 129 patients with hip fractures. After randomization, at the start of the surgery, 65 patients received a single dose of 1 gram of intravenous TXA (TXA group), and 64 received a placebo (placebo group). The primary effectiveness outcomes were the total blood loss and transfusion rate. The primary safety outcome was the rate of thromboembolic events. Data on surgical or medical infection, readmission and death were also collected. Results: The TXA group had a significant decrease in blood loss (p = 0.006) and requirement for transfusion (p < 0.001) compared with the placebo group. Likewise, there were no thromboembolic events in the TXA group and seven in the placebo group (p = 0.006). Mortality within 1-year postoperatively was not significantly different (p = 0.115). Conclusion: Using a single dose of intravenous TXA at the start of the surgery significantly reduces blood loss and the requirement for transfusion without increasing the risk of thromboembolic events or mortality within 1-year postoperatively in patients with hip fracture undergoing surgery. Registration number: NCT03211286. https://clinicaltrials.gov/ct2/show/NCT03211286. Level of evidence: I

    Puesta a punto y simulación del concentrador fresnel lineal de 86 m2 instalado en San Carlos

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    En este trabajo se muestra la puesta a punto de un Concentrador Lineal tipo Fresnel el cual está siendo instalado en la ciudad de San Carlos (Salta) en el marco del proyecto PFIP 2009 del MINCYT. El prototipo de concentrador fue construido a escala real con un factor de concentración cercano a 40 y un área de colección de 86m2 correspondientes a dos módulos instalados en serie. El ensayo preliminar permitió corroborar el correcto desempeño de las partes que forman el sistema completo. Mediante el software SIMUSOL se simuló el comportamiento térmico del equipo en condiciones normales de funcionamiento. Este programa es una herramienta útil para simulación de sistemas térmicos y predice correctamente el comportamiento de este equipoFil: Altamirano, Martin. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Salta. Instituto de Invest.en Energia No Convencional; Argentina;Fil: Hongn, Marcos Ezequiel. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Salta. Instituto de Invest.en Energia No Convencional; Argentina;Fil: Fernandez, C.. Universidad Nacional de Salta; Argentina;Fil: Bárcena, Humberto Francisco. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Salta. Instituto de Invest.en Energia No Convencional; Argentina;Fil: Hoyos, Daniel. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Salta. Instituto de Invest.en Energia No Convencional; Argentina;Fil: Saravia Mathon, Luis Roberto. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Salta. Instituto de Invest.en Energia No Convencional; Argentina;Fil: Flores Larsen, Silvana Elinor. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Salta. Instituto de Invest.en Energia No Convencional; Argentina;Fil: Gea, Marcelo Daniel. Universidad Nacional de Salta; Argentina;Fil: Placco, Cora. Universidad Nacional de Salta; Argentina;Fil: Suligoy, Hugo Cesar. Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Salta. Instituto de Invest.en Energia No Convencional; Argentina

    Identifying patterns and recommendations of and for sustainable open data initiatives:A benchmarking-driven analysis of open government data initiatives among European countries

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    Open government and open (government) data are seen as tools to create new opportunities, eliminate or at least reduce information inequalities and improve public services. More than a decade of these efforts has provided much experience, practices, and perspectives to learn how to better deal with them. This paper focuses on benchmarking of open data initiatives over the years and attempts to identify patterns observed among European countries that could lead to disparities in the development, growth, and sustainability of open data ecosystems. To do this, we studied benchmarks and indices published over the last years (57 editions of 8 artifacts) and conducted a comparative case study of eight European countries, identifying patterns among them considering different potentially relevant contexts such as e-government, open government data, open data indices and rankings, and others relevant for the country under consideration. Using a Delphi method, we reached a consensus within a panel of experts and validated a final list of 94 patterns, including their frequency of occurrence among studied countries and their effects on the respective countries. Finally, we took a closer look at the developments in identified contexts over the years and defined 21 recommendations for more resilient and sustainable open government data initiatives and ecosystems and future steps in this area.</p

    Identifying patterns and recommendations of and for sustainable open data initiatives: a benchmarking-driven analysis of open government data initiatives among European countries

    Get PDF
    Open government and open (government) data are seen as tools to create new opportunities, eliminate or at least reduce information inequalities and improve public services. More than a decade of these efforts has provided much experience, practices, and perspectives to learn how to better deal with them. This paper focuses on benchmarking of open data initiatives over the years and attempts to identify patterns observed among European countries that could lead to disparities in the development, growth, and sustainability of open data ecosystems. To do this, we studied benchmarks and indices published over the last years (57 editions of 8 artifacts) and conducted a comparative case study of eight European countries, identifying patterns among them considering different potentially relevant contexts such as e-government, open government data, open data indices and rankings, and others relevant for the country under consideration. Using a Delphi method, we reached a consensus within a panel of experts and validated a final list of 94 patterns, including their frequency of occurrence among studied countries and their effects on the respective countries. Finally, we took a closer look at the developments in identified contexts over the years and defined 21 recommendations for more resilient and sustainable open government data initiatives and ecosystems and future steps in this area.Regional Government of Andalusia, Spain (Research projects number P20_00314 and B-SEJ-556-UGR20).Institutional support of the University of Pardubice and by European Social Fund via IT Academy programme, University of Tartu (Estonia

    Chemical analysis of early-type stars with planets

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    Aims. Our goal is to explore the chemical pattern of early-type stars with planets, searching for a possible signature of planet formation. In particular, we study a likely relation between the λ Boötis chemical pattern and the presence of giant planets. Methods. We performed a detailed abundance determination in a sample of early-type stars with and without planets via spectral synthesis. Fundamental parameters were initially estimated using Strömgren photometry or literature values and then refined by requiring excitation and ionization balances of Fe lines. We derived chemical abundances for 23 different species by fitting observed spectra with an iterative process. Synthetic spectra were calculated using the program SYNTHE together with local thermodynamic equilibrium ATLAS12 model atmospheres. We used specific opacities calculated for each star, depending on the individual composition and microturbulence velocity vmicro through the opacity sampling method. The complete chemical pattern of the stars were then compared to those of λ Boötis stars and other chemically peculiar stars. Results. We compared the chemical pattern of the stars in our sample (13 stars with planets and 24 stars without detected planets) with those of λ Boötis and other chemically peculiar stars. We have found four λ Boötis stars in our sample, two of which present planets and circumstellar disks (HR 8799 and HD 169142) and one without planets detected (HD 110058). We have also identified the first λ Boötis star orbited by a brown dwarf (ζ Del). This interesting pair, the λ Boötis star and brown dwarf, could help to test stellar formation scenarios. We found no unique chemical pattern for the group of early-type stars bearing giant planets. However, our results support, in principle, a suggested scenario in which giant planets orbiting pre-main-sequence stars possibly block the dust of the disk and result in a λ Boötis-like pattern. On the other hand, we do not find a λ Boötis pattern in different hot-Jupiter planet host stars, which does not support the idea of possible accretion from the winds of hot-Jupiters, recently proposed in the literature. As a result, other mechanisms should account for the presence of the λ Boötis pattern between main-sequence stars. Finally, we suggest that the formation of planets around λ Boötis stars, such as HR 8799 and HD 169142, is also possible through the core accretion process and not only gravitational instability.Fil: Saffe, Carlos. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: Miquelarena Hollger, Paula Andrea. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: Alacoria, José Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: Flores Trivigno, Matias Gaston. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: Jaque Arancibia, Marcelo Daniel. Universidad de La Serena; ChileFil: Calvo, Daniela. Universidad Nacional de San Juan; ArgentinaFil: Martin Girardi, Gimena. Universidad Nacional de San Juan; ArgentinaFil: Grosso, Monica Gladys. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; ArgentinaFil: Collado, Ana Elisa. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio. Universidad Nacional de San Juan. Instituto de Ciencias Astronómicas, de la Tierra y del Espacio; Argentin
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