32 research outputs found

    Central Santa Catarina coastal dunefields chronology and their relation to relative sea level and climatic changes

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    During the past decades, there have been contrarian explanations for the formation and stabilization of coastal dunefields: while many authors believe the dunes formation would be enhanced by falling sea level, others argue that a rising or stable sea level context would be favorable. For Brazilian coastal dunefields, the second hypothesis seems to be more consistent with the luminescence ages found so far; however, most of these data were obtained without using the SAR protocol. Another point of concern is the role of climate change in the aeolian system, which is still not very clear. The aim of this paper is to try to clarify these two questions. To this end, five coastal dunefields were selected in central Santa Catarina coast. The remote sensing and dating results allowed the discrimination and mapping of at least four aeolian generations. Their age distribution in relation to the global curve of relative sea level variation during the Late Pleistocene allows us to suggest that the formation of Aeolian dunefields in the coastal context is supported by stable relative sea level. However, relative sea level is not the only determinant for the formation and preservation of the aeolian coastal dunes. Evidences of climatic control indicate that the initiation of dunefields would be favored by periods of less humidity while their stabilization would occur preferably during the periods of rain intensification, connected to monsoon activity

    Portaria 044/CCB/2009

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    Coordenadora Módulo I - Fonoaudiologia - Eliane Goldfeder

    A EXPANSÃO DA CADEIA DA SOJA NA AMAZÔNIA: OS CASOS DO PARÁ E AMAZONAS

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    Desde o início da década de 1990, a Amazônia legal brasileira vem sendo palco da expansão do plantio de soja e da atuação de empresas esmagadoras de grãos. Nos últimos anos a logística instalada pelo complexo agroindustrial sojicultor, a partir de produtores, fornecedores de insumos, processadores de matérias primas, assume um caráter estratégico e promove o avanço de novas fronteiras agrícolas no interior da região. A abundância de terras agriculturáveis, juntamente com a facilidade de escoamento via transporte fluvial através dos rios que cortam a bacia amazônica para o oceano Atlântico e daí para mercados consumidores na América do Norte, Europa e Ásia, são elementos que chamam a atenção das grandes tradings internacionais, e de empresas nacionais, que visam o mercado interno, mas principalmente o agronegócio exportador. Esses grupos empresariais criam vínculos econômicos entre o espaço regional e o comércio internacional. Neste sentindo este artigo busca analisar o contexto mais geral desta discussão, discutindo o lugar estratégico da cadeia de soja no processo de inserção global do sistema agroalimentar brasileiro, mas centrado foco em dois estudos de caso na região amazônica: Santarém no Pará e Humaitá no Amazonas

    RAR-independent RXR signaling induces t(15;17) leukemia cell maturation.

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    Although retinoic acid receptor alpha (RARalpha) agonists induce the maturation of t(15;17) acute promyelocytic leukemia (APL) cells, drug treatment also selects leukemic blasts expressing PML-RARalpha fusion proteins with mutated ligand-binding domains that no longer respond to all-trans retinoic acid (ATRA). Here we report a novel RARalpha-independent signaling pathway that induces maturation of both ATRA-sensitive and ATRA-resistant APL NB4 cells, and does not invoke the ligand-induced alteration of PML-RARalpha signaling, stability or compartmentalization. This response involves a cross-talk between RXR agonists and protein kinase A signaling. Our results indicate the existence of a separate RXR-dependent maturation pathway that can be activated in the absence of known ligands for RXR heterodimerization partners
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