Understanding the Comorbidity of Asthma and Anxiety in Childhood: Characteristics, Vulnerabilities, and Treatment Implications

This study examined potential differences in youth (aged 7-17 years, 76% Caucasian, 52% female) with comorbid asthma and anxiety compared to youth with anxiety without asthma who received cognitive-behavioral therapy (CBT) alone, pharmacotherapy alone, the combination of pharmacotherapy or placebo pill in the Child/Adolescent Multimodal Study. Two groups were compared on negative self-talk; number of physical symptoms; parental anxiety; content of their worries; and presence of panic, generalized anxiety, and separation anxiety disorders across treatment conditions. Findings indicated that youth with asthma and anxiety were more likely to exhibit higher rates of negative self-talk than youth without asthma, possibly related to the realistic nature of asthma-related anxiety. This study also demonstrated that youth with asthma and anxiety demonstrated similar responses to traditional CBT when compared to youth without asthma. Given the large sample size, these findings support that traditional CBT and pharmacotherapy for anxiety may be an effective treatment for youth with mild to moderate asthma. Further research is needed to determine the efficacy of traditional CBT for youth with severe asthma

Mishlavim Project - the Inclusion of Youth With Special Needs Into National Youth Service in Israel: Program Evaluation Research (2003-2004)

Mishlavim Project - the Inclusion of Youth With Special Needs Into National Youth Service in Israel: Program Evaluation Research (2003-2004

Understanding the Comorbidity of Asthma and Anxiety in Childhood: Characteristics, Vulnerabilities, and Treatment Implications

Introduction: Given the high incidence of asthma and anxiety comorbidity, clinicians should be informed of the unique presentation of these clients in clinical practice. Although much is known about the development and characteristics of childhood anxiety, less is known about children with anxiety and comorbid asthma. Methods: This study, using archival data, examined the potential differences in children with comorbid asthma and anxiety compared to children with anxiety from a random controlled trial. These two groups were compared on negative self-talk, number of physical symptoms, parent anxiety, content of their worries, and presence of panic, generalized anxiety, and separation anxiety disorder. Both groups were compared on their responsiveness to traditional Cognitive Behavioral Treatment for Childhood Anxiety. Discussion: Findings will contribute to more effective ways of addressing asthma in psychotherapy

Volunteers of National Youth Service in Israel: A Study on Motivation for Service, Social Attitudes, and Volunteers\u27 Satisfaction

Volunteers of National Youth Service in Israel: A Study on Motivation for Service, Social Attitudes, and Volunteers\u27 Satisfactio

Collaboration: Talk. Trust. Write.

This essay describes the professional collaborative writing process and activities of several pairs of prominent authors in English education

Intraseasonal Dynamics and Dominant Sequences in H3N2 Influenza

Long-term influenza evolution has been well studied, but the patterns of sequence diversity within seasons are less clear. H3N2 influenza genomes sampled from New York State over ten years indicated intraseasonal changes in evolutionary dynamics. Using the mean Hamming distance of a set of amino acid or nucleotide sequences as an indicator of its diversity, we found that influenza sequence diversity was significantly higher during the early epidemic period than later in the influenza season. Diversity was lowest during the peak of the epidemic, most likely due to the high prevalence of a single dominant amino acid sequence or very few dominant sequences during the peak epidemic period, corresponding with rapid expansion of the viral population. The frequency and duration of dominant sequences varied by influenza protein, but all proteins had an abundance of one distinct sequence during the peak epidemic period. In New York State from 1995 to 2005, high sequence diversity during the early epidemic suggested that seasonal antigenic drift could have occurred primarily in this period, followed by a clonal expansion of typically one clade during the peak of the epidemic, possibly indicating a shift to neutral drift or purifying selection

The presence of postmenopausal bleeding as prognostic parameter in patients with endometrial cancer: a retrospective multi-center study

Abstract Background To date, there is no consensus on the utility of screening procedures for the early detection of endometrial cancer. The value of transvaginal ultrasound for screening of asymptomatic endometrial cancer has been discussed controversially. This study was conducted to evaluate whether asymptomatic patients with endometrial cancer have a better prognosis than symptomatic patients with endometrial cancer diagnosed after postmenopausal bleeding. Methods In the present multi-center study, the effect of the presence of postmenopausal bleeding on prognosis was evaluated retrospectively in 605 patients with endometrial cancer using patients' files. 543 patients (133 patients were asymptomatic, 410 patients were symptomatic) with endometrioid endometrial cancer were enrolled in all further analysis. Student's t-test, Cox regression analysis and Kaplan-Meier analysis were used were appropriate. Results Presence/absence of a postmenopausal bleeding was not associated with tumor stage (p = 0.2) and age at diagnosis (p = 0.5). Asymptomatic patients with endometrial cancer had a significantly higher rate of well and moderate-differentiated tumors compared to symptomatic patients (p = 0.008). In univariable and multivariable survival analysis, tumor stage, tumor grade, and patients' age at diagnosis, but not presence/absence of a postmenopausal bleeding, were associated with disease free and overall survival. Conclusion Asymptomatic patients with endometrial cancer have a higher rate of well differentiated tumors compared to patients with a postmenopausal bleeding prior to diagnosis. The prognosis of both groups of patients was similar.</p