LABORATORY PARAMETERS OF CEREBROSPINAL FLUID IN INDIVIDUALS WITH ENTEROVIRUS MENINGITIS: A DESCRIPTIVE STUDY

Introduction: Meningitis is the leading infectious syndrome that affects the central nervous system, and most cases are caused by viral infections, mainly enterovirus. The clinical diagnosis for meningitis etiology still presents major challenges. The analysis of polymerase chain reaction (PCR), white blood cells, red blood cells, glucose, protein, and lactate in the cerebrospinal fluid (CSF) provides the first clues to the diagnosis. However, the reference values of some parameters can suffer changes. Objective: Analyze laboratory parameters of CSF in patients with enterovirus meningitis according to age. Methods: A descriptive study was conducted based on data from a CSF reference service, located in São Paulo, Brazil, on 202 individuals who had enterovirus meningitis. Data was analysed by the Shapiro–Wilk and Kruskal–Wallis tests (CI = 95%, p <0.05) and represented by the median and percentile 25 and 75, respectively. Results: The cytological and biochemical parameters of the CSF shows us that proteins had median concentrations of 33.0mg/dL, glucose of 57.0mg/dl, lactate of 19.0mg/dL and the leukocyte of 119.0 cells/mm 3, with a predominance of lymphocytes (42%). It was found that age can cause cytological and biochemical changes in the parameters of CSF. Children younger than 2 years had a range percentage of neutrophils and monocytes different then children aged e” 2 and <6 years, and aged e” 6 and <10 years. The protein concentration range in CSF as well as glucose track can also change according to age. Conclusion: Age may lead to changes in cytological and biochemical parameters of CSF. CSF protein and glucose concentrations also change according to age

Corrosion and tribocorrosion behaviour of Ti6Al4V produced by selective laser melting and hot pressing in comparison with the commercial alloy

The corrosion and tribocorrosion behaviour of SLM-produced Ti6Al4V alloy was studied in comparison with its HP and commercial counterparts in 9 g/L NaClsolution at body temperature. Results showed that SLM processing route influenced the electrochemical response of the SLM-produced alloy by leading to a relatively lower quality for the passive film due to decreased beta phase and the formation of alpha' phase. However, after tribocorrosion, neither the total volume loss nor the volume loss under the influence of mechanical wear and wear accelerated corrosion showed any statistically significant difference between the processing routes.This study was supported by FCT with the reference project UID/EEA/04436/2013, by FEDER funds through the COMPETE 2020 - Program Operacional Competitividade e Internacionalizacao (POCI) with the reference project POCI-01-0145-FEDER-006941, together with projects NORTE-01-0145-FEDER-000018-HAMaBICo and PTDC/EMS-TEC/5422/2014. The authors would also like to acknowledge Prof. Grata Minas for the provision of the profilometry

REGISTRO DA LAGOSTA SAPATEIRA Scyllarides brasiliensis RATHBUN, 1906 (DECÁPODA: SCYLLARIDAE) NO GRANDE SISTEMA DE RECIFES AMAZÔNICOS, PARÁ, BRASIL

The slipper lobster Scyllarides brasiliensis Rathbun, 1906 (Scyllaridae Latreille, 1825) has a broad distribution in Western Atlantic, however with disjoint records in costal zones between 20 and 40 m, associated in bottoms of gravel and coral reefs. From Brazilian waters, this species has been recorded from States of Maranhão to Bahia and with sporadic records in States of São Paulo and Santa Catarina. Based on that, herein we report the northernmost record of S. brasiliensis in Brazil and its first observation from the Amazon Reef System (ARS). A male specimen was collected through the lobster fishing boat (commercial fishing) in State of Pará (01°23’53.952” N; 046°40’46.452” W) at the depth of 76.2 m. This new record increases the geographic distribution of S. brasiliensis from State of Pará (Brazil) and expands the knowledge of the crustacean biodiversity in the Amazon Reefs.Keywords: Amazon River Mouth; Bycatch, Lobster; Northernmost Record; Scyllaridae.A lagosta sapateira Scyllarides brasiliensis Rathbun, 1906 (Scyllaridae Latreille, 1825) possui uma ampla distribuição no Oeste do Atlântico, com distribuição disjunta em zonas costeiras entre 20 e 40 m, onde se encontra associada a fundos de cascalho e recifes de corais. Em águas Brasileiras, essa espécie tem sido registrada dos Estados do Maranhão à Bahia e com registros esporádicos nos Estados de São Paulo e Santa Catarina. Baseado nisso, aqui nos reportamos o registro mais ao norte de S. brasiliensis no Brasil e sua primeira observação para o Sistema de Recifes Amazônicos (SRA). Um espécime macho foi coletado através do barco de pesca de lagosta (pesca comercial) no Estado do Pará (01°23’53,952” N; 046°40’46,452” O), na profundidade de 76.2 m. Esse novo registro aumenta a distribuição geográfica de S. brasiliensis para o Estado do Pará (Brasil) e expande o conhecimento da biodiversidade de crustáceos para o Sistema de Recifes Amazônicos.Palavras-chaves: Fauna acompanhante, Foz do Rio Amazonas, Lagosta, Registro mais ao Norte, Scyllaridae

REGISTRO DA LAGOSTA SAPATEIRA Parribacus antarcticus (LUND, 1793) (DECAPODA, SCYLLARIDAE) NO GRANDE SISTEMA DE RECIFE DA AMAZÔNIA, PA/ BRASIL

The sculptured slipper lobster Parribacus antarcticus (Lund, 1793), Family Scyllaridae Latreille, 1825, is reported for the first time on the Great Amazon Reef System, Pará, Brazil. The specimen, three females and two males, were collected in October and November 2019, at depths from 75.6 up to 101.4 m, by commercial fishing fleet. This report extends the area of occurrence of this specie on northern Brazil. Keywords: Bycatch; Northern coast; lobster fishery.  A lagosta sapateira Parribacus antarcticus (Lund, 1793), pertencente à família Scyllaridae Latreille, 1825, é relatada pela primeira vez no Grande Sistema de Recifes da Amazônia, Pará, Brasil. Os espécimes, três fêmeas e dois machos, foram coletados nos meses de outubro e novembro de 2019, na faixa de profundidade de 75,6 m a 101,4 m, durante pesca comercial para lagostas. O atual registro amplia o conhecimento da área de ocorrência dessa espécie no Norte do Brasil.Palavras-chave: Fauna acompanhante, Pesca da lagosta, Litoral Norte

Trombose de veia porta: revisão de literatura e relato de caso

Os autores apresentam o caso de uma mulher de 78 anos, com trombose venosa de veia porta. De acordo com uma hipótese recente, tromboses venosas, em geral, ocorrem apenas quando vários fatores são combinados. Esses fatores incluem distúrbios herdados ou adquiridos pró-trombótico, outros fatores trombofílicos, e fatores locais.  O diagnóstico é realizado através da ultrassonografia abdominal com Doppler. A questão central da terapêutica é o uso de anticoagulante. O tratamento é direcionado para as complicações, incluindo profilaxia primária e secundária de hemorragia digestiva alta (que resulta da ruptura de varizes esofágicas), e derivações porto-sistêmicas, em casos selecionados. Dessa forma, uma abordagem diagnóstica e terapêutica adequada é desejável na tentativa de se reduzir a morbimortalidade. Os autores apresentam uma breve revisão da literatura, e discutem o caso clínico

Diretriz sobre Diagnóstico e Tratamento da Cardiomiopatia Hipertrófica – 2024

Hypertrophic cardiomyopathy (HCM) is a form of genetically caused heart muscle disease, characterized by the thickening of the ventricular walls. Diagnosis requires detection through imaging methods (Echocardiogram or Cardiac Magnetic Resonance) showing any segment of the left ventricular wall with a thickness > 15 mm, without any other probable cause. Genetic analysis allows the identification of mutations in genes encoding different structures of the sarcomere responsible for the development of HCM in about 60% of cases, enabling screening of family members and genetic counseling, as an important part of patient and family management. Several concepts about HCM have recently been reviewed, including its prevalence of 1 in 250 individuals, hence not a rare but rather underdiagnosed disease. The vast majority of patients are asymptomatic. In symptomatic cases, obstruction of the left ventricular outflow tract (LVOT) is the primary disorder responsible for symptoms, and its presence should be investigated in all cases. In those where resting echocardiogram or Valsalva maneuver does not detect significant intraventricular gradient (> 30 mmHg), they should undergo stress echocardiography to detect LVOT obstruction. Patients with limiting symptoms and severe LVOT obstruction, refractory to beta-blockers and verapamil, should receive septal reduction therapies or use new drugs inhibiting cardiac myosin. Finally, appropriately identified patients at increased risk of sudden death may receive prophylactic measure with implantable cardioverter-defibrillator (ICD) implantation.La miocardiopatía hipertrófica (MCH) es una forma de enfermedad cardíaca de origen genético, caracterizada por el engrosamiento de las paredes ventriculares. El diagnóstico requiere la detección mediante métodos de imagen (Ecocardiograma o Resonancia Magnética Cardíaca) que muestren algún segmento de la pared ventricular izquierda con un grosor > 15 mm, sin otra causa probable. El análisis genético permite identificar mutaciones en genes que codifican diferentes estructuras del sarcómero responsables del desarrollo de la MCH en aproximadamente el 60% de los casos, lo que permite el tamizaje de familiares y el asesoramiento genético, como parte importante del manejo de pacientes y familiares. Varios conceptos sobre la MCH han sido revisados recientemente, incluida su prevalencia de 1 entre 250 individuos, por lo tanto, no es una enfermedad rara, sino subdiagnosticada. La gran mayoría de los pacientes son asintomáticos. En los casos sintomáticos, la obstrucción del tracto de salida ventricular izquierdo (TSVI) es el trastorno principal responsable de los síntomas, y su presencia debe investigarse en todos los casos. En aquellos en los que el ecocardiograma en reposo o la maniobra de Valsalva no detecta un gradiente intraventricular significativo (> 30 mmHg), deben someterse a ecocardiografía de esfuerzo para detectar la obstrucción del TSVI. Los pacientes con síntomas limitantes y obstrucción grave del TSVI, refractarios al uso de betabloqueantes y verapamilo, deben recibir terapias de reducción septal o usar nuevos medicamentos inhibidores de la miosina cardíaca. Finalmente, los pacientes adecuadamente identificados con un riesgo aumentado de muerte súbita pueden recibir medidas profilácticas con el implante de un cardioversor-desfibrilador implantable (CDI).A cardiomiopatia hipertrófica (CMH) é uma forma de doença do músculo cardíaco de causa genética, caracterizada pela hipertrofia das paredes ventriculares. O diagnóstico requer detecção por métodos de imagem (Ecocardiograma ou Ressonância Magnética Cardíaca) de qualquer segmento da parede do ventrículo esquerdo com espessura > 15 mm, sem outra causa provável. A análise genética permite identificar mutações de genes codificantes de diferentes estruturas do sarcômero responsáveis pelo desenvolvimento da CMH em cerca de 60% dos casos, permitindo o rastreio de familiares e aconselhamento genético, como parte importante do manejo dos pacientes e familiares. Vários conceitos sobre a CMH foram recentemente revistos, incluindo sua prevalência de 1 em 250 indivíduos, não sendo, portanto, uma doença rara, mas subdiagnosticada. A vasta maioria dos pacientes é assintomática. Naqueles sintomáticos, a obstrução do trato de saída do ventrículo esquerdo (OTSVE) é o principal distúrbio responsável pelos sintomas, devendo-se investigar a sua presença em todos os casos. Naqueles em que o ecocardiograma em repouso ou com Manobra de Valsalva não detecta gradiente intraventricular significativo (> 30 mmHg), devem ser submetidos à ecocardiografia com esforço físico para detecção da OTSVE.   Pacientes com sintomas limitantes e grave OTSVE, refratários ao uso de betabloqueadores e verapamil, devem receber terapias de redução septal ou uso de novas drogas inibidoras da miosina cardíaca. Por fim, os pacientes adequadamente identificados com risco aumentado de morta súbita podem receber medida profilática com implante de cardiodesfibrilador implantável (CDI)

Catálogo Taxonômico da Fauna do Brasil: setting the baseline knowledge on the animal diversity in Brazil

The limited temporal completeness and taxonomic accuracy of species lists, made available in a traditional manner in scientific publications, has always represented a problem. These lists are invariably limited to a few taxonomic groups and do not represent up-to-date knowledge of all species and classifications. In this context, the Brazilian megadiverse fauna is no exception, and the Catálogo Taxonômico da Fauna do Brasil (CTFB) (http://fauna.jbrj.gov.br/), made public in 2015, represents a database on biodiversity anchored on a list of valid and expertly recognized scientific names of animals in Brazil. The CTFB is updated in near real time by a team of more than 800 specialists. By January 1, 2024, the CTFB compiled 133,691 nominal species, with 125,138 that were considered valid. Most of the valid species were arthropods (82.3%, with more than 102,000 species) and chordates (7.69%, with over 11,000 species). These taxa were followed by a cluster composed of Mollusca (3,567 species), Platyhelminthes (2,292 species), Annelida (1,833 species), and Nematoda (1,447 species). All remaining groups had less than 1,000 species reported in Brazil, with Cnidaria (831 species), Porifera (628 species), Rotifera (606 species), and Bryozoa (520 species) representing those with more than 500 species. Analysis of the CTFB database can facilitate and direct efforts towards the discovery of new species in Brazil, but it is also fundamental in providing the best available list of valid nominal species to users, including those in science, health, conservation efforts, and any initiative involving animals. The importance of the CTFB is evidenced by the elevated number of citations in the scientific literature in diverse areas of biology, law, anthropology, education, forensic science, and veterinary science, among others

A new species of the genus Mezilaurus Taubert (Lauraceae) for the Brazilian flora

(A new species of the genus Mezilaurus Taubert (Lauraceae) for the brazilian flora). The species was named Mezilaurus vanderwerffii F. M. Alves & J.B. Baitello and is characterized by leaves with dense, glandular dots on the adaxial surface. The species is reported for Cerrado, Cerradao, and Semideciduous Forest surrounding the Pantanal Matogrossens

Nectandra Rol. ex Rottb. (Lauraceae) in Mato Grosso do Sul State, Brazil

(Nectandra Rol. ex Rottb. (Lauraceae) in Mato Grosso do Sul State, Brazil). This paper presents the taxonomic study of the species of Nectandra from Mato Grosso do Sul. Eight species of Nectandra were identified through the morphological analyses of specimens collected in different regions from the State: N. amazonum Nees, N. cissiflora Nees, N. cuspidata Nees, N. falcifolia (Nees) J.A. Castigl. ex Mart. Crov. & Piccinini, N. gardneri Meisn., N. hihua (Ruiz & Pav.) Rohwer, N. megapotamica (Spreng.) Mez and N. psammophila Nees. Identification key, morphological descriptions, geographic distribution, habitat, fenologic aspect, taxonomic comments, and illustrations are presented