The Dardanella Blues

https://digitalcommons.library.umaine.edu/mmb-vp/5391/thumbnail.jp

Low-Dissipation Advection Schemes Designed for Large Eddy Simulations of Hypersonic Propulsion Systems

The 2nd-order upwind inviscid flux scheme implemented in the multi-block, structured grid, cell centered, finite volume, high-speed reacting flow code VULCAN has been modified to reduce numerical dissipation. This modification was motivated by the desire to improve the codes ability to perform large eddy simulations. The reduction in dissipation was accomplished through a hybridization of non-dissipative and dissipative discontinuity-capturing advection schemes that reduces numerical dissipation while maintaining the ability to capture shocks. A methodology for constructing hybrid-advection schemes that blends nondissipative fluxes consisting of linear combinations of divergence and product rule forms discretized using 4th-order symmetric operators, with dissipative, 3rd or 4th-order reconstruction based upwind flux schemes was developed and implemented. A series of benchmark problems with increasing spatial and fluid dynamical complexity were utilized to examine the ability of the candidate schemes to resolve and propagate structures typical of turbulent flow, their discontinuity capturing capability and their robustness. A realistic geometry typical of a high-speed propulsion system flowpath was computed using the most promising of the examined schemes and was compared with available experimental data to demonstrate simulation fidelity

Between Pragmatism and Idealism: Implementing a Systemic Approach to Capacity Development

Implementing a systemic approach to capacity development is more challenging than stakeholders expect and can be difficult to communicate to colleagues, donors and intended beneficiaries. This article explores challenges faced by the IDS Knowledge Services as it sought to turn an understanding of capacity development into practice. Drawing on the experience of one small scale programme it argues that: • for organisations to facilitate capacity development, they themselves need to change; • customary understandings of capacity development are an obstacle to effective demand?led approaches; • promoting critical reflection may be the most sustainable activity for facilitating capacity development. It concludes that the process of translating an understanding of capacity development into practice requires treading a line between pragmatism and idealism. This approach has ethical and practical challenges which capacity development practitioners need to counter by considering the impact that they have on others, by being aware of their own capacity and working to change understandings of capacity development

Dardanella

[Verse 1] Down beside the Dardanella Bay, Where Oriental breezes play, There lives a lonesome maid, Armenian. By the Dardanelles with glowing eyes, She looks across the seas and sighs, And weaves her love spell so Sirenian. Soon I shall return to Turkestan, I will ask for her heart and hand: [Chorus] Oh sweet Dardanella, I love your harem eyes, I’m a lucky fellow to capture such a prize, Oh Allah knows, my love for you And he tells you to be true, Dardanella, Oh hear my sigh, my Oriental, Oh sweet Dardanella, prepare the wedding wine, There’ll be one girl in my harem, when you’re mine. We’ll build a tent Just like the children of the Orient. Oh sweet Dardanella, my star of live divine. [Verse 2] When the Turkish Sultan saw her eyes, Oh he was taken by surprise, He said I’ll buy her for my Harem. I just told the Sultan to be nice. She can’t be brought for any price, She said to me she couldn’t bear him. So beneath the Oriental moon, I’ll be wooing my love real soon: [Chorus

Histological and transcriptomic effects of 17α-methyltestosterone on zebrafish gonad development.

BACKGROUND: Sex hormones play important roles in teleost ovarian and testicular development. In zebrafish, ovarian differentiation appears to be dictated by an oocyte-derived signal via Cyp19a1a aromatase-mediated estrogen production. Androgens and aromatase inhibitors can induce female-to-male sex reversal, however, the mechanisms underlying gonadal masculinisation are poorly understood. We used histological analyses together with RNA sequencing to characterise zebrafish gonadal transcriptomes and investigate the effects of 17α-methyltestosterone on gonadal differentiation. RESULTS: At a morphological level, 17α-methyltestosterone (MT) masculinised gonads and accelerated spermatogenesis, and these changes were paralleled in masculinisation and de-feminisation of gonadal transcriptomes. MT treatment upregulated expression of genes involved in male sex determination and differentiation (amh, dmrt1, gsdf and wt1a) and those involved in 11-oxygenated androgen production (cyp11c1 and hsd11b2). It also repressed expression of ovarian development and folliculogenesis genes (bmp15, gdf9, figla, zp2.1 and zp3b). Furthermore, MT treatment altered epigenetic modification of histones in zebrafish gonads. Contrary to expectations, higher levels of cyp19a1a or foxl2 expression in control ovaries compared to MT-treated testes and control testes were not statistically significant during early gonad development (40 dpf). CONCLUSION: Our study suggests that both androgen production and aromatase inhibition are important for androgen-induced gonadal masculinisation and natural testicular differentiation in zebrafish

Academic Vocabulary Strategies

This module will provide K-12 educators, in various content areas, with research-based academic vocabulary strategies that can be used to inform their instructional practices. The module explains the term academic vocabulary in depth and addresses the importance of students being able to read, interpret, and analyze vocabulary in context. After viewing several research-based strategies, the module will provide educators with tools to plan for and assess the implementation of the vocabulary strategies. Visit professional learning module.https://digitalcommons.gardner-webb.edu/improve/1010/thumbnail.jp