Analysis of the simultaneity factor of fast-charging sites using Monte-Carlo simulation

Given the increasing number of battery electric vehicles, the availability of suitable fast-charging infrastructure is crucial. However, designing such sites requires enough capacity in the electric power grid. A major influencing factor on the effect of fast-charging sites on the power grid is the simultaneity factor, i.e. the share of installed power related to the theoretical maximum power. The aim of this work is to investigate optimal simultaneity factors for fast-charging sites depending on various influencing factors. Real-world charging data from the biggest German operator is used in a stochastic approach via Monte-Carlo Simulation. It was found that in most cases, fast-charging sites can be designed with a simultaneity factor of 0.5 to satisfy demand. Applying this would reduce the effect on the power grid as well as reduce costs and time to build charging infrastructure. In consequence, the demand of the rising electric vehicle number can be met more efficiently

Stratigraphy and sedimentology of a basement-onlapping shallow marine sandstone succession, the Charcot Bugt Formation, Middle–Upper Jurassic, East Greenland

A rocky shore developed in early Middle Jurassic times by transgression of the crystalline basement in Milne Land at the western margin of the East Greenland rift basin. The basement is onlapped by shallow marine sandstones of the Charcot Bugt Formation, locally with a thin fluvial unit at the base. The topography of the onlap surface suggests that a relative sea-level rise of at least 300 m took place in Early Bathonian – Middle Oxfordian times. The sea-level rise was punctuated by relative stillstands and falls during which progradation of the shoreline took place. Palynological data tied to the Boreal ammonite stratigraphy have greatly improved time resolution within the Charcot Bugt Formation, and the Jurassic succession in Milne Land can now be understood in terms of genetically-related depositional systems with a proximal to distal decrease in grain size. The sequence stratigraphic interpretation suggests that translation of the depositional systems governed by relative sea-level changes resulted in stacking of sandstone-dominated falling stage deposits in the eastern, basinwards parts of Milne Land, whereas thick, remarkably coarse-grained transgressive systems tract deposits formed along the western basin margin. The bulk of the Charcot Bugt Formation consists of stacked sandstone-dominated shoreface units that prograded during highstands. The overall aggradational to backstepping stacking pattern recognised in the Charcot Bugt Formation is comparable to that in the contemporaneous Pelion Formation of the Jameson Land Basin and in correlative units of the mid-Norway shelf and the Northern North Sea. We suggest that the long-term evolution of the depositional systems may have been controlled by long-term eustatic rise acting in concert with relative sea-level changes reflecting regionally contemporaneous phases of rift initiation, climax and gradual cessation of rifting

Rocking Newton’s cradle

In textbook descriptions of Newton’s cradle, it is generally claimed that displacing one ball will result in a collision that leads to another ball being ejected from the line, with all others remaining motionless. Hermann and Schmälzle, Hinch and Saint-Jean, and others have shown that a realistic description is more subtle. We present a simulation of Newton’s cradle that reproduces the break-up of the line of balls at the first collision, the eventual movement of all the balls in phase, and is in good agreement with our experimentally obtained data. The first effect is due to the finite elastic response of the balls, and the second is a result of viscoelastic dissipation in the impacts. We also analyze a dissipation-free ideal Newton’s cradle which displays complex dynamics.This work was funded by Enterprise Ireland (Basic Research Grant No. SC/2000/239/Y) for one of the authors (S. H.) and a Trinity College Dublin Research Studentship for another (G. D.

Influence of Smoking on Colonic Gene Expression Profile in Crohn's Disease

BACKGROUND: The development and course of Crohn's disease (CD) is related to both genetic and environmental factors. Smoking has been found to exacerbate the course of CD by increasing the risk of developing fistulas and strictures as well as the need for surgery, possibly because of an interaction between smoking or nicotine on macrophage function and the intestinal microvasculature. Several genes are involved in the pathogenesis of CD, and in this study the gene expression differences of the descending colonic mucosa were investigated in CD (smokers or never smokers) and controls (smokers or never smokers). AIM: To identify any difference in gene expression of the descending colonic mucosa between smoking and never-smoking CD patients (and controls) by determining genetic expression profiles from microarray analysis. METHODS: Fifty-seven specimens were obtained by routine colonoscopy from the included material: CD smokers (n = 28) or never-smokers (n = 14) as compared to fifteen healthy controls (8 smokers and 7 never-smokers). RNA was isolated and gene expression assessed with Affymetrix GeneChip Human Genome U133 Plus 2.0. Data were analyzed by principal component analysis (PCA), Wilcoxon rank sum test and multiple linear regressions. Real-time (RT) PCR was subsequently applied to verify microarray results. RESULTS: The PCA analysis showed no intrinsic clustering of smokers versus never-smokers. However, when Wilcoxon rank sum test corrected with Q values were performed, six known genes were significantly expressed differently in the inflamed CD smokers as compared to the inflamed CD never-smokers: ring finger protein 138 (RNF138), metalothionein 2A (MT2A) and six transmembrane epithelial antigen of the prostate 3 (STEAP3), SA hypertension-associated homolog, PGM2L1 and KCNJ2. The subsequent RT-PCR-analyses verified, however, that only RNF138, MT2A and STEAP3 were significantly up-regulated in CD smokers in specimens with inflammatory activity of the descending colon. CONCLUSIONS: The present study demonstrates that the genes, RNF138, MT2A, and STEAP3 are differently expressed in the inflamed descending colon of smoking versus never-smoking CD patients, which might be of relevance for the poorer clinical course among CD smokers. Many gastroenterologists are still not totally aware of the benefits of smoking cessation in relation to CD, and do not put much effort into getting the patients to quit, therefore more information on the negative effects of smoking, seems warranted

Potential impact of texture analysis in contrast enhanced CT in non-small cell lung cancer as a marker of survival: A retrospective feasibility study

The objective of this feasibility study was to assess computed tomography (CT) texture analysis (CTTA) of pulmonary lesions as a predictor of overall survival in patients with suspected lung cancer on contrast-enhanced computed tomography (CECT). In a retrospective pilot study, 94 patients (52 men and 42 women; mean age, 67.2 ± 10.8 yrs) from 1 center with non-small cell lung cancer (NSCLC) underwent CTTA on the primary lesion by 2 individual readers. Both simple and multivariate Cox regression analyses correlating textural parameters with overall survival were performed. Statistically significant parameters were selected, and optimal cutoff values were determined. Kaplan-Meier plots based on these results were produced. Simple Cox regression analysis showed that normalized uniformity had a hazard ratio (HR) of 16.059 (3.861-66.788, P < .001), and skewness had an HR of 1.914 (1.330-2.754, P < .001). The optimal cutoff values for both parameters were 0.8602 and 0.1554, respectively. Normalized uniformity, clinical stage, and skewness were found to be prognostic factors for overall survival in multivariate analysis. Tumor heterogeneity, assessed by normalized uniformity and skewness on CECT may be a prognostic factor for overall survival

Modular Open-Source Design of Pyrolysis Reactor Monitoring and Control Electronics

Industrial pilot projects often rely on proprietary and expensive electronic hardware to control and monitor experiments. This raises costs and retards innovation. Open-source hardware tools exist for implementing these processes individually; however, they are not easily integrated with other designs. The Broadly Reconfigurable and Expandable Automation Device (BREAD) is a framework that provides many open-source devices which can be connected to create more complex data acquisition and control systems. This article explores the feasibility of using BREAD plug-and-play open hardware to quickly design and test monitoring and control electronics for an industrial materials processing prototype pyrolysis reactor. Generally, pilot-scale pyrolysis plants are expensive custom designed systems. The plug-and-play prototype approach was first tested by connecting it to the pyrolysis reactor and ensuring that it can measure temperature and actuate heaters and a stirring motor. Next, a single circuit board system was created and tested using the designs from the BREAD prototype to reduce the number of microcontrollers required. Both open-source control systems were capable of reliably running the pyrolysis reactor continuously, achieving equivalent performance to a state-of-the-art commercial controller with a ten-fold reduction in the overall cost of control. Open-source, plug-and-play hardware provides a reliable avenue for researchers to quickly develop data acquisition and control electronics for industrial-scale experiments

Terapijska procena ličnosti - kolaborativni pristup

Studies in the field of psychodiagnostis usually apply to presentation of some techniques and innovations in order to improve the quality and reliability of the obtained data. However, it remains to be answered how are all these data and their interpretation and integration used, and what their purpose is. Therapeutic evaluation has been developed as a new and logical answer to the old question. The paper presents the basic principles of this approach to personality evaluation.Radovi iz oblasti psihodijagnostike uglavnom se odnose na prikaz pojedinačnih tehnika i novina u cilju poboljšanja kvaliteta i pouzdanosti dobijenih podataka. Međutim, postavlja se pitanje kako se svi ti podaci i njihova interpretacija i integracija koriste, čemu ili kome zapravo oni služe? Terapijska procena nastala je kao nov i logičan odgovor na ovo staro pitanje. U ovom radu predstavljene su osnovne postavke ovog pristupa proceni ličnosti