389 research outputs found
The effect of confounding data features on a deep learning algorithm to predict complete coronary occlusion in a retrospective observational setting
An experimental evaluation of StatHand:A free application to guide students’ statistical decision making
Arming the Outlaws: On the Moral Limits of the Arms Trade
There is a general presumption against arming outlaw states. But can that
presumption sometimes be overturned? The argument considered here
maintains that outlaw states can have legitimate security interests, and
that transferring weapons to these states can be an appropriate way of
promoting those interests. Weapons enable governments to engage in
wrongful oppression and aggression, but they also enable them to fend off predators in a manner that can be beneficial to their citizens. It clearly
does not follow from the fact that a state is oppressive or aggressive that it will never be a victim of wrongful aggression itself, and while an outlaw
state’s primary aim in repelling such aggression will often be the
preservation of its own power, its defensive manoeuvres will sometimes
also serve its citizens’ interests. In short, supplying weapons to outlaw
states may sometimes contribute to the protection of innocents
Nuclear Transparency to Intermediate-Energy Protons
Nuclear transparency in the (e,e'p) reaction for 135 < Tp < 800 MeV is
investigated using the distorted wave approximation. Calculations using
density-dependent effective interactions are compared with phenomenological
optical potentials. Nuclear transparency is well correlated with proton
absorption and neutron total cross sections. For Tp < 300 MeV there is
considerable sensitivity to the choice of optical model, with the empirical
effective interaction providing the best agreement with transparency data. For
Tp > 300 MeV there is much less difference between optical models, but the
calculations substantially underpredict transparency data and the discrepancy
increases with A. The differences between Glauber and optical model
calculations are related to their respective definitions of the semi-inclusive
cross section. By using a more inclusive summation over final states the
Glauber model emphasizes nucleon-nucleon inelasticity, whereas with a more
restrictive summation the optical model emphasizes nucleon-nucleus
inelasticity; experimental definitions of the semi-inclusive cross section lie
between these extremes.Comment: uuencoded gz-compressed tar file containing revtex and bbl files and
5 postscript figures, totalling 31 pages. Uses psfi
Acceleration of relativistic beams using laser-generated terahertz pulses
Dielectric structures driven by laser-generated terahertz (THz) pulses may
hold the key to overcoming the technological limitations of conventional
particle accelerators and with recent experimental demonstrations of
acceleration, compression and streaking of low-energy (sub-100 keV) electron
beams, operation at relativistic beam energies is now essential to realize the
full potential of THz-driven structures. We present the first THz-driven linear
acceleration of relativistic 35 MeV electron bunches, exploiting the collinear
excitation of a dielectric-lined waveguide driven by the longitudinal electric
field component of polarization-tailored, narrowband THz pulses. Our results
pave the way to unprecedented control over relativistic electron beams,
providing bunch compression for ultrafast electron diffraction, energy
manipulation for bunch diagnostics, and ultimately delivering high-field
gradients for compact THz-driven particle acceleration.Comment: 8 pages, 4 figure
Assessment of the conjunctival microcirculation for patients presenting with acute myocardial infarction compared to healthy controls
Quantitative assessment of the conjunctival microcirculation using a smartphone and slit-lamp biomicroscope
Purpose: The conjunctival microcirculation is a readily-accessible vascular bed for quantitative haemodynamic assessment and has been studied previously using a digital charge-coupled device (CCD). Smartphone video imaging of the conjunctiva, and haemodynamic parameter quantification, represents a novel approach. We report the feasibility of smartphone video acquisition and subsequent haemodynamic measure quantification via semi-automated means. Methods: Using an Apple iPhone 6 s and a Topcon SL-D4 slit-lamp biomicroscope, we obtained videos of the conjunctival microcirculation in 4 fields of view per patient, for 17 low cardiovascular risk patients. After image registration and processing, we quantified the diameter, mean axial velocity, mean blood volume flow, and wall shear rate for each vessel studied. Vessels were grouped into quartiles based on their diameter i.e. group 1 (<11 μm), 2 (11–16 μm), 3 (16–22 μm) and 4 (>22 μm). Results: From the 17 healthy controls (mean QRISK3 6.6%), we obtained quantifiable haemodynamics from 626 vessel segments. The mean diameter of microvessels, across all sites, was 21.1μm (range 5.8–58 μm). Mean axial velocity was 0.50mm/s (range 0.11–1mm/s) and there was a modestly positive correlation (r 0.322) seen with increasing diameter, best appreciated when comparing group 4 to the remaining groups (p < .0001). Blood volume flow (mean 145.61pl/s, range 7.05–1178.81pl/s) was strongly correlated with increasing diameter (r 0.943, p < .0001) and wall shear rate (mean 157.31 s − 1, range 37.37–841.66 s − 1) negatively correlated with increasing diameter (r − 0.703, p < .0001). Conclusions: We, for the first time, report the successful assessment and quantification of the conjunctival microcirculatory haemodynamics using a smartphone-based system. </p
Fructose reprogrammes glutamine-dependent oxidative metabolism to support LPS-induced inflammation
A Simple HEPA Filtering Facepiece
Shortages of efficient filtering facepiece respirators leave the public vulnerable to transmission of infectious diseases in small particle aerosols. This study demonstrates that a high-filtration-efficiency facepiece capable of filtering out >95% of 0.05μm particles while being worn can be simply produced with available materials
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