Diagnostics of Coronal Magnetic Fields Through the Hanle Effect in UV and IR Lines

The plasma thermodynamics in the solar upper atmosphere, particularly in the corona, are dominated by the magnetic field, which controls the flow and dissipation of energy. The relative lack of knowledge of the coronal vector magnetic field is a major handicap for progress in coronal physics. This makes the development of measurement methods of coronal magnetic fields a high priority in solar physics. The Hanle effect in the UV and IR spectral lines is a largely unexplored diagnostic. We use magnetohydrodynamic (MHD) simulations to study the magnitude of the signal to be expected for typical coronal magnetic fields for selected spectral lines in the UV and IR wavelength ranges, namely the H I Ly-$\alpha$ and the He I 10830 {\AA} lines. We show that the selected lines are useful for reliable diagnosis of coronal magnetic fields. The results show that the combination of polarization measurements of spectral lines with different sensitivities to the Hanle effect may be most appropriate for deducing coronal magnetic properties from future observations.Comment: 15 pages, 5 figures, Frontiers in Astronomy and Space Sciences, 201

The meaning of different forms of structural myocardial injury, immune response and timing of infarct necrosis and cardiac repair

Although a decline in the all-cause and cardiac mortality rates following myocardial infarction (MI) during the past 3 decades has been reported, MI is a major cause of death and disability worldwide. From a pathological point of view MI consists in a particular myocardial cell death due to prolonged ischemia. After the onset of myocardial ischemia, cell death is not immediate, but takes a finite period of time to develop. Once complete myocytes’ necrosis has occurred, a process leading to a healed infarction takes place. In fact, MI is a dynamic process that begins with the transition from reversible to irreversible ischemic injury and culminates in the replacement of dead myocardium by a fibrous scar. The pathobiological mechanisms underlying this process are very complex, involving an inflammatory response by several pathways, and pose a major challenge to ability to improve our knowledge. An improved understanding of the pathobiology of cardiac repair after MI and further studies of its underlying mechanisms provide avenues for the development of future strategies directed toward the identification of novel therapies. The chronologic dating of MI is of great importance both to clinical and forensic investigation, that is, the ability to create a theoretical timeline upon which either clinicians or forensic pathologists may increase their ability to estimate the time of MI. Aging of MI has very important practical implications in clinical practice since, based on the chronological dating of MI, attractive alternatives to solve therapeutic strategies in the various phases of MI are developing

Confocal laser scanning microscope, raman microscopy and western blotting to evaluate inflammatory response after myocardial infarction

Cardiac muscle necrosis is associated with inflammatory cascade that clears the infarct from dead cells and matrix debris, and then replaces the damaged tissue with scar, through three overlapping phases: the inflammatory phase, the proliferative phase and the maturation phase. Western blotting, laser confocal microscopy, Raman microscopy are valuable tools for studying the inflammatory response following myocardial infarction both humoral and cellular phase, allowing the identification and semiquantitative analysis of proteins produced during the inflammatory cascade activation and the topographical distribution and expression of proteins and cells involved in myocardial inflammation. Confocal laser scanning microscopy (CLSM) is a relatively new technique for microscopic imaging, that allows greater resolution, optical sectioning of the sample and three-dimensional reconstruction of the same sample. Western blotting used to detect the presence of a specific protein with antibody-antigen interaction in the midst of a complex protein mixture extracted from cells, produced semi-quantitative data quite easy to interpret. Confocal Raman microscopy combines the three-dimensional optical resolution of confocal microscopy and the sensitivity to molecular vibrations, which characterizes Raman spectroscopy. The combined use of western blotting and confocal microscope allows detecting the presence of proteins in the sample and trying to observe the exact location within the tissue, or the topographical distribution of the same. Once demonstrated the presence of proteins (cytokines, chemokines, etc.) is important to know the topographical distribution, obtaining in this way additional information regarding the extension of the inflammatory process in function of the time stayed from the time of myocardial infarction. These methods may be useful to study and define the expression of a wide range of inflammatory mediators at several different timepoints providing a more detailed analysis of the time course of the infarct

Response to the letter by Meng-jun Zhan et al. regarding the paper \u201cA technical report from the Italian SARS-CoV-2 outbreak. Postmortem sampling and autopsy investigation in cases of suspected or probable COVID-19\u201d

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In situ spectroscopy of the solar corona

Context. Future spacecraft missions, such as the proposed Solar Probe mission, will venture close to the Sun, allowing spectrometers measuring emission from heavy ions or neutrals in the solar wind to have radial lines of sight (LOS) pointing away from the Sun, or indeed in any direction other than sunwards. Aims. We show that a radial LOS gives excellent solar wind diagnostics, with tight constraints on ion density, outflow velocity, and effective temperature parallel to the coronal magnetic field. In addition, we present the concept that a spectrometer onboard a spacecraft reaching the solar corona can yield measurements somewhat similar to an in situ sampling instrument, in that the 3D velocity distribution and density of the emitting ions can be measured. Methods. The well-studied O VI doublet at 1031.96 and 1037.6 Å and the H Ly-α line at 1215.67 Å are chosen as examples. Solar wind parameters obtained from a 2D three-fluid magnetohydrodynamic (MHD) model, and formulations for collisional and radiative emission along a radial LOS, are used to calculate spectral line profiles for these lines at various heights within a streamer and coronal hole. Results. For O VI, the collisional line profiles directly measure the ion velocity distribution in the radial direction, with the general Doppler shift of the profiles related to the bulk ion outflow velocity and the width of the line related to the effective ion temperature parallel to the magnetic field. An obvious skew in the collisional profiles is seen in regions with a high gradient in outflow velocity and/or temperature. The resonant (or radiative) line profiles behave very differently from those currently observed in 90° scattering. They are more closely related to the profile and distribution of the exciting chromospheric spectrum: the lines are narrow and are centered at wavelengths mirrored around the rest wavelength of the ion emission, allowing easy separation of the collisional and radiative components. Despite the Ly-α line being much more intense than the O VI lines, the large width and high intensity of the Ly-α radiative component in comparison to the collisional component is such that these two components cannot be separated. The Ly-α line is therefore less suitable for solar wind diagnostics. Conclusions. The prospect of coronal in situ spectral observations, combined with simultaneous in situ sampling measurements of the solar wind and magnetic field will give unsurpassed constraints on models of solar wind heating and acceleration

Hepatic laceration due to umbilical venous catheter malpositioning

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Visibility of prominences using the He i D3 line filter on PROBA-3/ASPIICS coronagraph

We determine the optimal width and shape of the narrow-band filter centered on the He i D3 line for prominence and coronal mass ejection (CME) observations with the ASPIICS (Association of Spacecraft for Polarimetric and Imaging Investigation of the Corona of the Sun) coronagraph onboard the PROBA-3 (Project for On-board Autonomy) satellite, to be launched in 2020. We analyze He i D3 line intensities for three representative non-local thermal equilibrium prominence models at temperatures 8, 30, and 100 kK computed with a radiative transfer code and the prominence visible-light (VL) emission due to Thomson scattering on the prominence electrons. We compute various useful relations at prominence line-of-sight velocities of 0, 100, and 300 km s−1 for 20 Å wide flat filter and three Gaussian filters with a full-width at half-maximum (FWHM) equal to 5, 10, and 20 Å to show the relative brightness contribution of the He i D3 line and the prominence VL to the visibility in a given narrow-band filter. We also discuss possible signal contamination by Na i D1 and D2 lines, which otherwise may be useful to detect comets. Our results mainly show that i) an optimal narrow-band filter should be flat or somewhere between flat and Gaussian with an FWHM of 20 Å in order to detect fast-moving prominence structures, ii) the maximum emission in the He i D3 line is at 30 kK and the minimal at 100 kK, and iii) the ratio of emission in the He i D3 line to the VL emission can provide a useful diagnostic for the temperature of prominence structures. This ratio is up to 10 for hot prominence structures, up to 100 for cool structures, and up to 1000 for warm structures