459 research outputs found
Applying and Extending the Sustainable Value Method related to Agriculture â an Overview
Sustainable Value is a method to measure the contribution of an economic entity, such as a farm or the entire agricultural sector, towards the sustainability (sustainable development) of a region, a country or on a global scale. A positive sustainable value is created once resources are used more efficiently than by a benchmark. It shows the excess return that is created or lost by the use of economic, environmental and social resources by an economic entity relative to a benchmark. The purpose of this paper is to give an overview on the characteristics and requirements of the SV and to provide information on (a) possible applications and (b) extensions of the SV method related to the agricultural sector. A particular emphasis is put on the choice of sustainability indicators (resource figures, welfare figure) to be included, the generic steps of SV calculation, the meaning of weighting and aggregation in the SV, the role of the Return-to-Cost Ratio in taking farm size into consideration, and the interpretation and communication of the results of an agriculture-related SV assessment. After sketching out possible extensions and variations of the SV method, the paper closes with a summary of those aspects to keep in mind when applying the SV to agriculture.sustainability contributions, value, measurement, Environmental Economics and Policy,
Reshaping Global Change Science for the 21st Century: Young Scientistsâ Perspectives
Humanity is facing unprecedented environmental, social, and economic challenges. We ask what the role of the global science community should be in tackling these challenges. Increased awareness of the social context in which science is being produced; acceptance of the importance of controversy; and reflection around normative assumptions underlying research are needed. To help solve humanityâs grand challenges scientists need to move towards a transdisciplinary view of science where knowledge emerges from a collaborative environment and where young scientists are trained to work across disciplinary boundaries and engage with policy communities
Defect distribution in a-plane GaN on Al2O3
The authors studied the structural and point defect distributions of hydride vapor phase epitaxial GaN film grown in the [11â20] a direction on (1â102) r-plane sapphire with metal-organic vapor phase deposited a-GaN template using transmission electron microscopy, secondary ion mass spectrometry, and positron annihilation spectroscopy. Grown-in extended and point defects show constant behavior as a function of thickness, contrary to the strong nonuniform defect distribution observed in GaN grown along the [0001] direction. The observed differences are explained by orientation-dependent and kinetics related defect incorporation.Peer reviewe
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Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets
The majority of today's antimicrobial therapeutics is derived from secondary metabolites produced by Actinobacteria. While it is generally assumed that less than 1% of Actinobacteria species from soil habitats have been cultivated so far, classic screening approaches fail to supply new substances, often due to limited throughput and frequent rediscovery of already known strains. To overcome these restrictions, we implement high-throughput cultivation of soil-derived Actinobacteria in microfluidic pL-droplets by generating more than 600000 pure cultures per hour from a spore suspension that can subsequently be incubated for days to weeks. Moreover, we introduce triggered imaging with real-time image-based droplet classification as a novel universal method for pL-droplet sorting. Growth-dependent droplet sorting at frequencies above 100 Hz is performed for label-free enrichment and extraction of microcultures. The combination of both cultivation of Actinobacteria in pL-droplets and real-time detection of growing Actinobacteria has great potential in screening for yet unknown species as well as their undiscovered natural products
Re-shaping Sustainability Science for the 21st Century: Young Scientistsâ Perspectives
Humanity is facing unprecedented environmental, social and economic challenges. We ask what the role of the sustainability science community should be in tackling these challenges, focusing particularly on young scientistsâ perspectives on the issue. On the basis of a questionnaire and a workshop with young scientists, we identify four major challenges facing humanity and develop three guidelines for sustainability science that seeks to address them. Results show that to help address humanityâs grand challenges, sustainability scientists need to move towards a trans-disciplinary system view of science and sustainability science problems. According to this view knowledge emerges from a collaborative and transdisciplinary environment and young scientists are trained to work across disciplinary boundaries and engage with policy communities
Supersymmetry in carbon nanotubes in a transverse magnetic field
Electron properties of Carbon nanotubes in a transverse magnetic field are
studied using a model of a massless Dirac particle on a cylinder. The problem
possesses supersymmetry which protects low energy states and ensures stability
of the metallic behavior in arbitrarily large fields. In metallic tubes we find
suppression of the Fermi velocity at half-filling and enhancement of the
density of states. In semiconducting tubes the energy gap is suppressed. These
features qualitatively persist (although to a smaller degree) in the presence
of electron interactions. The possibilities of experimental observation of
these effects are discussed.Comment: A new section on electron interaction effects added and explanation
on roles of supersymmetry expanded. Revtex4, 6 EPS figure file
Towards a Sustainable Governance of Information Systems: Devising a Maturity Assessment Tool of Eco-Responsibility Inspired by the Balanced Scorecard
Part 3: Section 2: Sustainable and Responsible InnovationInternational audienceThe assessment of the maturity of Information System (IS) regarding its contribution to corporate social responsibility policy is considered as a stake for organizations. However, few research efforts have been dedicated to this evaluation and even less to the elaboration of a management tool. This paper adopts an engineering perspective to develop a performance assessment approach in this field. Theoretically, this communication (1) mobilizes the methodology of engineering research to build a measurement system of the IS maturity in relation to the economic, social and environmental performance, (2) extends the researches about the sustainable balanced scorecard (SBSC) to the field of IS governance. Practically, this study provides organizations with a global approach to this complex phenomenon as well as a guide to assess it. The originality of this research lies in the application of the conceptual framework of the SBSC to a new research domain
Aspf2 From Aspergillus fumigatus Recruits Human Immune Regulators for Immune Evasion and Cell Damage
The opportunistic fungal pathogen Aspergillus fumigatus can cause life-threatening infections, particularly in immunocompromised patients. Most pathogenic microbes control host innate immune responses at the earliest time, already before infiltrating host immune cells arrive at the site of infection. Here, we identify Aspf2 as the first A. fumigatus Factor H-binding protein. Aspf2 recruits several human plasma regulators, Factor H, factor-H-like protein 1 (FHL-1), FHR1, and plasminogen. Factor H contacts Aspf2 via two regions located in SCRs6â7 and SCR20. FHL-1 binds via SCRs6â7, and FHR1 via SCRs3â5. Factor H and FHL-1 attached to Aspf2-maintained cofactor activity and assisted in C3b inactivation. A Îaspf2 knockout strain was generated which bound Factor H with 28% and FHL-1 with 42% lower intensity. In agreement with less immune regulator acquisition, when challenged with complement-active normal human serum, Îaspf2 conidia had substantially more C3b (>57%) deposited on their surface. Consequently, Îaspf2 conidia were more efficiently phagocytosed (>20%) and killed (44%) by human neutrophils as wild-type conidia. Furthermore, Aspf2 recruited human plasminogen and, when activated by tissue-type plasminogen activator, newly generated plasmin cleaved the chromogenic substrate S2251 and degraded fibrinogen. Furthermore, plasmin attached to conidia damaged human lung epithelial cells, induced cell retraction, and caused matrix exposure. Thus, Aspf2 is a central immune evasion protein and plasminogen ligand of A. fumigatus. By blocking host innate immune attack and by disrupting human lung epithelial cell layers, Aspf2 assists in early steps of fungal infection and likely allows tissue penetration
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