1,785 research outputs found

    Art, Gaut and Games: the Case for Why Some Video Games Are Art

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    In this paper, I argue that there are some video games which are art. I begin my paper by laying out several objections as to why video games could not be art. After laying out these objections, I present the theory of art I find most persuasive, Berys Gaut’s cluster concept of art. Because of the nature of Gaut’s cluster concept, I argue that video games, as a medium of expression, do not need to be defended as a whole. Rather, like all other media of expression, only certain works are worthy of the title art. I then introduce and defend several games as art. After, I return to the initial objections against video games and respond in light of my defended cases. I conclude that video games, as a medium of expression, are still growing, but every day there are more examples of video games as art

    Construction of MV - and SMV - optimum designs for binary response models.

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    Recently, Dette and Sahm (1998) have put forward a procedure to construct MV-and SMV-optimurn designs for binary response models. In order to implement computationally this procedure some assumptions have to be made and some theoretical results must be proved. This paper provides the background to produce a computer code for computing local designs for different regions of the parameters of the model. Designs for some models used in practice are also provided as well as the efficiencies for estima the parameters

    Changes in murine anorectum signaling across the life course

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    Background: Increasing age is associated with an increase in the incidence of chronic constipation and fecal impaction. The contribution of the natural aging process to these conditions is not fully understood. This study examined the effects of increasing age on the function of the murine anorectum.Methods: The effects of increasing age on cholinergic, nitrergic, and purinergic signaling pathways in the murine anorectum were examined using classical organ bath assays to examine tissue function and electrochemical sensing to determine age‐related changes in nitric oxide and acetylcholine release.Key Results: Nitrergic relaxation increased between 3 and 6 months, peaked at 12 months and declined in the 18 and 24 months groups. These changes were in part explained by an age‐related decrease in nitric oxide (NO) release. Cholinergic signaling was maintained with age by an increase in acetylcholine (ACh) release and a compensatory decrease in cholinesterase activity. Age‐related changes in purinergic relaxation were qualitatively similar to nitrergic relaxation although the relaxations were much smaller. Increasing age did not alter the response of the anorectum smooth muscle to exogenously applied ACh, ATP, sodium nitroprusside or KCl. Similarly, there was no change in basal tension developed by the anorectum.Conclusions and Inferences: The decrease in nitrergic signaling with increasing age may contribute to the age‐related fecal impaction and constipation previously described in this model by partially obstructing defecation

    MAGIC sensitivity to millisecond-duration optical pulses

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    The MAGIC telescopes are a system of two Imaging Atmospheric Cherenkov Telescopes (IACTs) designed to observe very high energy (VHE) gamma rays above ~50 GeV. However, as IACTs are sensitive to Cherenkov light in the UV/blue and use photo-detectors with a time response well below the ms scale, MAGIC is also able to perform simultaneous optical observations. Through an alternative system installed in the central PMT of MAGIC II camera, the so-called central pixel, MAGIC is sensitive to short (1ms - 1s) optical pulses. Periodic signals from the Crab pulsar are regularly monitored. Here we report for the first time the experimental determination of the sensitivity of the central pixel to isolated 1-10 ms long optical pulses. The result of this study is relevant for searches of fast transients such as Fast Radio Bursts (FRBs).Comment: Proceedings of the 35th International Cosmic Ray Conference (ICRC 2017), Bexco, Busan, Korea (arXiv:1708.05153

    Role of advanced technology in the detection of sight-threatening eye disease in a UK community setting.

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    Background/aims: To determine the performance of combinations of structural and functional screening tests in detecting sight-threatening eye disease in a cohort of elderly subjects recruited from primary care. Methods: 505 subjects aged ≄60 years underwent frequency doubling technology (FDT) perimetry, iVue optical coherence tomography (iWellness and peripapillary retinal nerve fibre layer (RNFL) scans) and intraocular pressure with the Ocular Response Analyzer, all performed by an ophthalmic technician. The reference standard was a full ophthalmic examination by an experienced clinician who was masked to the index test results. Subjects were classified as presence or absence of sight-threatening eye disease (clinically significant cataract, primary open-angle glaucoma, intermediate or advanced age-related macular degeneration and significant diabetic retinopathy). Univariate and multivariate logistic regression analyses were used to determine the association between abnormal screening test results and the presence of sight-threatening eye disease. Results: 171 subjects (33.8%) had one or more sight-threatening eye diseases. The multivariate analysis found significant associations with any of the target conditions for visual acuity of <6/12, an abnormal FDT and peripapillary RNFL thickness outside the 99% normal limit. The sensitivity of this optimised screening panel was 61.3% (95% CI 53.5 to 68.7), with a specificity of 78.8% (95% CI 74.0 to 83.1), a positive predictive value of 59.5% (95% CI 53.7 to 65.2) and an overall diagnostic accuracy of 72.9% (95% CI 68.8 to 76.8). Conclusions: A subset of screening tests may provide an accurate and efficient means of population screening for significant eye disease in the elderly. This study provides useful preliminary data to inform the development of further larger, multicentre screening studies to validate this screening panel

    Good Sleep Quality Improves the Relationship Between Pain and Depression Among Individuals With Chronic Pain

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    Individuals with chronic pain often experience co-existing sleep problems and depression-related states. Chronic pain, sleep problems, and depression interrelate, and have been shown to exacerbate one another, which negatively impacts quality of life. This study explored the relationships between pain severity, pain interference, sleep quality, and depression among individuals with chronic pain. Secondly, we tested whether sleep quality may moderate the relationship between pain and depression. A cross-sectional survey was completed by 1,059 adults with non-malignant chronic pain conditions (Mage 43 years, 88% identified as women) and collected measures related to pain severity, pain interference, sleep quality and depression. Multiple regression analyses found that pain severity, pain interference and sleep quality are all significantly associated with depression. Secondly, moderated regression analyses revealed that sleep quality moderates the relationship between pain interference and depression among individuals with chronic pain such that good sleep quality attenuates the effect of pain interference on depression, and poor sleep quality amplifies the effect of pain interference on depression. These findings suggest that sleep quality may be a relevant therapeutic target for individuals with chronic pain and co-existing depression

    An overview on the obsolescence of physical assets for the defence facing the challenges of industry 4.0 and the new operating environments

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    Libro en Open AccessThis contribution is intended to observe special features presented in physical assets for defence. Particularly, the management of defence assets has to consider not only the reliability, availability, maintainability and other factors frequently used in asset management. On the contrary, such systems should also take into account their adaptation to changing operating environments as well as their capability to changes on the technological context. This study approaches to the current real situation where, due to the diversity of conflicts in our international context, the same type of defence systems must be able to provide services under different boundary conditions in different areas of the globe. At the same time, new concepts from the Industry 4.0 provide quick changes that should be considered along the life cycle of a defence asset. As a finding or consequence, these variations in operating conditions and in technology may accelerate asset degradation by modifying its reliability, its up-to-date status and, in general terms, its end-of-life estimation, depending of course on a diversity of factors. This accelerated deterioration of the asset is often known as “obsolescence” and its implications are often evaluated (when possible), in terms of costs from different natures. The originality of this contribution is the introduction of a discussion on how a proper analysis may help to reduce errors and mistakes in the decision-making process regarding the suitability or not of repairing, replacing, or modernizing the asset or system under study. In other words, the obsolescence analysis, from a reliability and technological point of view, could be used to determine the conservation or not of a specific asset fleet, in order to understand the effects of operational and technology factors variation over the functionality and life cycle cost of physical assets for defence

    Authentic leadership’s effect on customer orientation and turnover intention among Portuguese hospitality employees: the mediating role of affective commitment

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    Purpose: Hospitality employees’ attitudes and behaviors play a crucial role in enhancing customer satisfaction and service quality and ultimately firms’ success; therefore, organizations must have skilled, customer-oriented staff. More research is required to help hospitality managers gain insights into the best strategies to promote and retain customer-oriented employees. This study specifically sought to provide a more comprehensive understanding of the ways that authentic leadership (AL) can affect employees’ customer orientation and turnover intention, including exploring affective commitment’s (AC) potential mediating role. Design/methodology/approach: The sample included 350 employees from different hospitality organizations in Portugal. Data were collected using anonymously completed structured questionnaires available online or in a paper-and-pencil format. Findings: The results demonstrate that AL has a positive effect on customer orientation and a negative effect on turnover intention. Moreover, they indicate that AC mediates the relationships between AL and both customer orientation and turnover intention. All hypotheses received empirical support. Practical implications: Hotel managers can increase employees’ AC and customer orientation by engaging in AL behaviors. Similarly, management can avoid having employees voluntarily leave their jobs using more AL styles and strengthening employees’ affective bonds to their organization. Originality/value: Prior hospitality studies have rarely focused on AL. This study is the first to analyze AL’s effect on customer orientation and AC’s role as a mediator variable in the relationships between AL and customer orientation and turnover intention, thus integrating all these variables into a single research model.info:eu-repo/semantics/acceptedVersio
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